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^appletseat to I n t e n t Koport o f March 23 1981
The field investigation,, ss described in the Interim ftsnort, was carried out an planned except that the period of time was extended to sixteen oaths instead of twelve, primarily for reasons of convenience in the completion of the second aeries of clinical examinations, `on this account there were five rounds of sampling of the urine, instead of the intended four, and the final samples of blood were obtained for comparison with the initial samples after an interval of approximately fifteen oaths instead of twelve.
All of the data, including those of the clinical examinations, had been usserubied by the end of the year 1901, and were subjected to careful scrutiny and statistical analysis. The final report is la preparation, but has hiron delayed in its completion because of other duties and obligations within the Scpartfiscat of preventive Medicine and industrial Health {of which The Tottering laboratory is an integral part) Including those associated with rudviafce instruction.
The data of primary importance are those indicative of the experience of the personnel engaged in the pertinent operationsof the petroleum industry.with respect to potential exposure to lead in the form of the tctraaetbyllead which has been added to gasoline. Other items of i n f a r c t i o n bearing on the atter under investigation, but less crucial in relation to the question of exposure t o #and absorption of, lead, are the clinical findings (physical and .laboratory findings, including hemtoiogical and ;-:-ray observations).' For present purposes these m y be disposed of briefly, Hone of the sen Included la the survey gave any evidence of illness referable to the absorption of lead, whether of complaints, physical sign
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or &fl;tmatological deviations. As to the latter, all of the findings uJc.y'?
in all of the personnel eome within normal limts, and the terminal findings, to the extent of their differences from the initial data, were in the direction of improvement. (This^almost certainly, was a fortuitous circumstance, whether of seasonal or other import^ The differences were significant in the statistical sense, but were not remarkable in the physiological sense.
The radiological observations were not intended to be especially relevant with respect to potential exposure to lead, but were regarded as desirable for other hygienic reasons. There were no findings that required further investigation.
The terminal samples of urine were obtained in July and August of 1961, the next-to-last series having been obtained in May and June. The second (final) series of samples of blood were obtained in July and August, at the time of the collection of the final series of samples of urine. Only a few of the men who were included initially were missing in the final round of sampling (and examination). Such minor discrepancies are shown by the numbers of samples represented in the several tables of data.
The analytical data, relative to the urine and blood, for the entire period of this survey, are assembled in a series of tables numbered from 1 through 10, attached hereto. Tables 1,2,3,7 and 9 are extensions of Tables 7,8,9 and 10 of the Interim Report (with some slight difference in arrangement). The "supplementary" tables, however, contain all of the analytical data and can be substituted for and added to those set forth in Part 2 of the Interim Report.
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in that there is no evidence of the
tee of occupational exposure to
lead, on the part of these men, because of the substitution of tetraaethyllead
for tetraethyllead in the gasoline which was being dispensed and otherwise
handled by them in the filling stations.
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Note: The additional information obtained in the final period of the survey of the lead in the air at the occupational sites contributed nothing new or aberrant. The data presented in Tables 1,2.3,4,5 and Q cf'/[`e \ehxTare entirely adequate in their representation of th facts with reference to lead in the atmospheric environment of the workmen in the various occupations
Director, The Kettering laboratory Department of Preventive Medicine
and Industrial Health.
Date: April 15, 1S62
^Prepared in time for a meeting and full discussion of the situation in the Office of the Assistant Secretary of Defense, Washington, D.C.,* April 17, 1962.
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