Document b5OR9yyMdYjXBLBdkb8zvG3z6

940 CHAPTER 44 . 1952 Guide Table 1. Temperatures and.Humidities; Applicable toIndustrial Air Conditioning--(Continued) Process | Temp. F K.H. % PAINT APPLICATION "- Lacquers: Oil Paints - 70-90 . . 180-300 75 60 60 Spray booths to have 100 fpm face velocity. Make-up air must be preheated. Ovens must have air removed to keep fumes below explosive concentration; Equipment must be explosion-proof throughout Room or Process Temp. F PHARMACEUTICAL R.H.% Biological manufacturing............................ .............................. Liver extracts............................................ ..; `. '.V.. - 70 to 80 75 to 80 80 70 to 80 80 90 75 to 80 70 80 78 to 80 80 78 75 ' 80 80 - 70 to 80 . 74 to 78 75 to 80 ., 75 to 78 30 to 35 40 35 15 30 30 to 50 40 ' 5 to 10 35 to 40 50 35 20 to 30 50 . . 40 47 to 48 ' Gelatin capsules require varying relative humidities, depending upon size of capsule. Moisture content should not exceed 0.25 gr pier cu ft. Various kinds of gelatin require different temperatures. Penicillin incubation process requires, .holding temperature within i deg F, with temperatures and hu midity rigidly controlled during all manufacturing phases. Ampule filling requires a 20 percent relative humidity when especially fine powders aroused.: Uncoated tablet manufacturing requires accurate control of temperature'mid relative humidity, since low relative humidity causes formation of a hard outer layer, and high relative humidity retards drying at the proper rate. Liver extracts require a low relative humidity after they are dried. Temperatures higher than 80 F will cause the extracts to deteriorate. ' Tablet coating requires the control of the temperatures of all ingredients and the temperature of air in troduced to coating pans. -t. ' Sterile conditions are essential in many pharmaceutical processes. Provide suitable air exhaust to re move surplus material from tablet compressing machine. Air filtration is generally required, with positive air filtration in some areas. Animal Rooms in Pharmaceutical Laboratories In the following tabulation each of the items'mentioned is equivalent in metabolism to one man: Quantity Animal Weight Each 672 110 73 70 21 16 .16 5 White Mice Rats Rats i:Guinea Pigs Rabbits Cats Monkeys Dogs 21 g 200 g 400 g 410 g 2.6 kg . 3.0kg . 3.0 kg . 14.0 kg . Dogs are generally, the worst offenders as far as.odor generation is concerned. t Decontamination of exhaust air is recommended in populated areas. For good air quality conditions the following space per animal and total air circulation (all outdoor or decontaminated in'recirculation) should be provided: nimft.1 . cu ft . . ,, . cfm Mice 3 ... 0.5 Rats 4 . 0.75 Guinea Pigs 6 1.0 Rabbits 10 1.9 Hamsters 8 1.5 Cats 35 10.0 Dogs 150 28.0 Industrial'Air Conditioning 941 , Table lv < Temperatures'and Humidities Applicable to Industrial ' Air Conditioning--(Continued) Process Temp. F R.H. % PHOTO STUDIO 74 75-80 70 72 70-75 60 ......... 50 - . 70 - - : 65 60 45 `r ' Heat liberated during printing, enlarging and drying processes is removed through an independent ex haust system, which also serveathelamp houses and dryer hoods. Dust control is essential, and absolute filtration is required in some areas. Process '. .Temp. F PHOTO MATERIAL R-H.% ; Nitrate Film Storage..7...................................................... 20-125 65-75 70-75 70-75 60-80 40-50 40-80 40-60 40-65 40-65 45-50 40-50 Spray water must have algae inhibitor. Positive dust control must be maintained and absolute filtra tion is essential. In nitrate film area take proper precautions against fires. . . ^ Recirculated air used for film drying is passed through activated carbon filters. Relative humidity for film storage should never exceed 60 percent with a minimum of 25: percent.' Process PLASTICS Manufacturing areas: ' Cellophane wrapping.;Li..;.. . .. ____. ... .>y .. ........... t*.. Absolute filtration is required in some areas. Collection and removal of dust'and fumes 'is essential. Temp. F ; 801 . 75 to 80 . ' R.H. % 25 to 30 45 to 65 ' n Process Temp. F R.H.% PLYWOOD 90 60 90 15 to 25 POULTRY RAISING Incubator.... ........................... ............................. Brooder: 1st week.............................................. .=.............................. 2nd week............................................................................. Battery room: Starting............................................................................... Growing........................................................................... . Egg storage............................................................................ 70-75 70-75 50-60 70 50-60 45-60 30-60 60 60 70-75 50-60 70-80 Maximum ventilation is required for laying quarters during the summer months, while an attempt is made to maintain a temperature 10 deg above or below outdoor temperature during the winter, to miwwiM condensation on the exterior walls. This applies to houses not having forced ventilation systems. Process Temp. F PRECISION MACHINING Spectrographic analysis......................... Gear matching A 'special assembly room Gasket storage........................................... Cement & glue storage.............................. Precision parts machining....................... . 75-80 75-80 100 65 75 R.H.% 45-50 35-40 50 40 45-50