Document aJy6QN9ZD2zQpOdQNmYx4GMYY
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CHAPTER 46
1957 Guide %
Table 1. Temperatures and Humidities Applicable to Industbial Aib
Conditioning--(Continued)
Process
Temp. F
R.H.%
PAINT APPLICATION
;V:
Lacquers; Air drying................................................................................. Baking.......................................................................................
Oil Paints Air drying.................................................................................
"Paint Spraying............................................................................
70-80 180-300
60-80 75
60 60
Spray booths to have.100 fpm face velocity. Make-up air must be preheated. Ovens must have air removed to keep fumes below explosive concentration. Equipment must be explosion-proof throughout
Room or Process
Temp. F PHARMACEUTICAL
R.H.%
Rm*)1 animal nvnm
70 to 80 75 to 80
80 70 to 80
80 90 75 to 80 70 80 78 to 80 80
75 80 80 70 to 80 74 to 78
75 to 78
15 to 35 35
30 30 to 50 5 to 10
47 to 48
Gelatin capsules require varying relative humidities, depending upon aiae of capsule. Moisture content should not exceed 0.25 gr per cu ft. Various kinds of gelatin require different temperatures.
Penicillin incubation process requires holding temperature within | deg F, with temperatures and hu midity rigidly controlled during all manufacturing phases.
Ampule filling requires a 20 peroent relative humidity when especially fine powders are used.
Uncoated tablet manufacturing requires accurate control of temperature and relative humidity, since low relative humidity causee formation of a hard outer layer, and high relative humidity retards drying at the proper rate.
Liver extracts require a low relative humidity after they are dried. Temperatures higher than SO F will cause the extracts to deteriorate.
Tablet coating requires the control of the temperatures of all ingredients and the temperature of air in troduced to coating pans.
Sterile conditions are essential in many pharmaceutical processes. Provide suitable air exhaust to re move surplus material from tablet compressing machine.
Air filtration is generally required, with positive air filtration in some areas.
Actual Rooms in Pharmaceutical Laboratories In the following tabulation each of the items mentioned is equivalent in metabolism to one man:
QuANnrr
Animal
Weight Each
673 White Mice
21 g
110 Rats
200 g
73 Rats
400 g
70
Guinea Pigs
410 g
21 Rabbits
2.6 kg
16 Cats
3.0 kg
16 Monkeys
3.0 kg
5 Dogs
14.0 kg
Dogs are generally the worst offenders as far as odor generation is concerned.
Decontamination of exhaust air is recommended in populated areas.
For good air quality conditions the following space per animal and total air circulation (all outdoor or
decontaminated in recirculation) should be provided:
Animal
cu ft
cfm
Mice
3 0.5
Rats
4 0.75
Guinea Pigs
6 1.0
Rabbits
10 1.9
Hamsters
8 1.5
Cats
35 10.0
Dogs
16C 28.0
Process and Product Air Conditioning
1125
Table 1. Temperatures and Humidities Applicable to Industbial Aib
Conditioning--(Continued)
Pbooess
| Temp. F | R.H. %
PHOTO STUDIO
Dressing Room. Drying Room... . Printing Room ... Setting^Room.. ..
Developing Room
Storage Rcx>*
74 75-80
70 72 70-75
60
30-40 50 70
65 60
45
Heat liberated during printing, enlarging and drying processes is removed through an independent ex haust system, which also serves the lamp houses ana dryer hoods.
Dust control is essential, and absolute filtration is required in some areas.
Process
Temp. F PHOTO MATERIAL
R.H. %
20-125 65-75
70-75 70-75 60-80 40-50
40-80 40-60 40-65
40-65 45-50 40-50
Spray water must have algae inhibitor. Positive dust control must be maintained and absolute filtra tion is essential.
In nitrate film area take proper precautions against fires. Recirculated air used for film drying is passed through activated carbon filters.
Relative humidity for film storage should never exoeed 60 percent with a minimum of 25 percent.
Process Manufacturing areas:
PLASTICS
Absolute filtration is required in some areas. Collection and removal of dust and fumes is essential.
Temp. F
80 75 to 80
R.H.%
25 to 30 45 to 65
Process
PLYWOOD
Temp. F
R.H.%
Cold Prwwing
90 60 90 16 to 25
POULTRY RAISING
Incubator....... Brooder:
1st week....... 2nd week.... battery room: Starting CrowiniF
*88 storage___
-
70-75
70-75 50-60
70 60-60 45-60
30-60
60 60
70-75 50-60 70-80
Maximum ventilation is required for laying quarters during the summer months, while an attempt is Bi&de to mamfa a temperature 10 deg above or below outdoor temperature during the winter, to minimise
condensation on the exterior walls. This applies to houses not'having forced ventilation systems.
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Process
Temp. F PRECISION MACHINING
Spectrographic analysis............................. basket atom* * Pecial assembly room..
Cement A glue storage.......... `TecWon parts maehmmg...........................
75-80
75-80 100 65 75
R.H. %
45-60 35-40
60 40 45-60