Document aDJ561peODLjNV7xjn6009NJN

( !t 'Dec. 14, 1932 PLAINTIFF'S EXHIBIT Dr. B. L. Yosbnrgh, General Slectric Company, Schenectady, H. Y. ' Dear Dr. Yosburgh: I think you can tell Hr. Doll that his last proposal, to use an alcohol denatured with 9.05 y by volume of Iso propanol- rill be quite safe, even if he has no artificial 1 ventilation. You are quite right that,according to That 1 is called Tti'chardson's Lax, the toxicity of the alcohols goes up as the series goes up, but. thatJlow hag no mean ing in industry. It is based on anlraalskxperiments in which the alcohols were given by intrav^ncus Injections, iiacht, of Johns Hopkins repeated Richardson's worTc and got the same results, but when he tried to do the same by in halation experiments he found quite different results, in fact inethyl alcohol was the only one to intoxicate markedly and iso-propyl alcohol had no effect at r.ll. .. Ybu see, in these Inst experiments, which am the only ones applicable to industry, &aoht was testing vola- tility,'and when one does that the series is just reversed. The higher the alcohol, the lower the volatility, that for .us it .works out just the opposite of Richardson s law. The iso-prepyl alcohol will not volatilize and so, industrial ly it is safe. Ae a matter of fact, re do not have any trou- ^ ble with alcohols practically, except methyl alcohol, the ! most volatile of all. ' Sincerely yours Alice Hamilton, 2-i.D. f