Document aB96z6Bw95B4dY56qx1QaVnmN

INTERNAL CORRESPONDENCE UNION CARBIDE CORPORATION old ridgebury road, oanbury. ct obsit To On/won u-eaoon Araa Susan G. Austin, Sc.D. HS & EA Epidemiology p2 Coov" _ November 11, 1982 o^o,n,nS^5 4 A Ar-- auomx Epidemiology, P2 Recalculation of ETO Exposure In The UCC~ Texas City Case ControT"Stu3y Dear Susan: While attempting to validate specific department codes which used ethylene oxide, an omislson was discovered on the original chemical-department group list (reference: 1/30/81 document from R.L. Frantz to S.S. Lefflngwell). Our in-house case-control study will have to be updated to reflect this discovery. The omislson was that ethylene oxide was not Included in DG016 (Chemicals Lab). The number of persons who had DG016 In their work history, and were not previously counted as exposed to ethylene oxide Is Included In the following table: ADDITIONAL EMPLOYEES EXPOSED TO ETHYLENE OXIDE WITH ADDITIONS TO TOTAL NUMBER OF EMPLOYEES WITH KNOWN EXPOSURES IN PARENTHESES Overall 15-Year Latency Cases Control 1 Control 2 Hourly Ctl 1 Hourly Ctl 2 1 i1) 4 (2) 1 i 2 (2) 1 (0) 1 (!) 3 (1) 1 0) 1 (1) 1 (0) The numbers In parenthesis are persons who were previously treated as unknown, so these persons are added to the total number In each group as well as the total number exposed. 1`ve enclosed changes that should be made on the case control report. Please let me know If you have any questions. ARS:gac Enclosure Sincerely, ^-- A. Robert Schnatter UCC 053171 XftBLE 3. Bcposure Status Of Cases And Controls for Five Chemicals (feed Or Produced At The Texas City Plant (1941-1977) CHBMICAL BENZENE DIETHYL SULFATE ETHYLENE DICHE0RIDB ETHYLS* GOODE VINYL CUIORIDB Btposed N (1) 1 (-8) 5 (23.8) 5 (23.8) 4 n.o .......... * 4 (19.0) CASES thexposed N () 8 (38.1) 6 (28.6) 6 (28.6) 1 7 (33.3) 1 CONTROL I 1 Unknown | Reposed Uhexposed unknown (Exposed N (%> 1 N () 1 N (%) N (*) IN () 1 1 12 (57.1)| 11 (13.8) 18 1 1 (22.5) 51 (63.8)1 5 (6.2) 1 1I 10 (47.6)( 17 (21.3) 18 (22.5) 45 (56.3)113 (16.3) 11 11 10 (47.6) | 14 (17.5) 19 (23.8) 47 (58.8)114 (17.5) to. 47.k! l. Ik.* 1 &ft*o 4? (IW) <49- 4.f h1 1a1u -0 11 11 10 (47.6)1 12 (15.0) 20 (25.0) 48 (60.0)(13 (16.2) CONTROL 11 Uhexposed N (%> 21 (26.3) 19 (23.8) 17 (21.3) 14 20- JAOCSA.)l 19 (23.8) Uhknown N (t) 54 (67.5) 48 (60.0) 49 (61.3) 47 U.* 4* (6t*0) 48 (60.0) ucc 053172 Table 4A. Proportions f Cases and Controls Bcposed to Five Chemicals at UCC Texas City CHEMICAL SEN^C UESUr SULFATE ETHYLQE DICHLORIDE EBIHBJE OXIDE VBKL CHLORIDE ALL CASES Peroent TOtal deposed 9 11.1 GLIGMAS Percent Total Bcposed 8 12.5 CONTROL I Percent Total Bcposed 29 37.9 OOMIROL II Percent Total Deposed 26 19.2 U 45.5 10 40.0 35 48.6 32 40.6 11 45.5 l( 4#- 10 50.0 33 42.4 31 45.2 lo 40.0 u 3^.4 & y.y *** ' 11 36.4 10 40.0 32 37.5 32 40.6 Table 4B. Proportions of Cases and Hourly Controls Bcposed to Five Chemicals at UCC Texas City CHBUCAL EQ4ZENE DIEnKLSULFATE ethxxbe DICHUDRIDE ETHIfLQC OXIDE VTNXL CHLORIDE ALL CASES Percent Total Bcposed 9 U.l GLIOMAS Percent Total Bcposed 8 12.5 CONTROL I Percent Ttotal Bcposed 26 38.5 CONTROL II Percent Total Bcposed 24 16.7 11 45.5 10 40.0 31 48.4 30 40.0 11 45.5 M S&t 10 50.0 jO.ft 30 43.3 36 29 44.8 y.s 11 36.4 10 30.0 29 37.9 29 37.9 UCC 053173 Table 5A. Proportions of Cases and Controls Exposed to Five Chemicals at UOC Texas City at Least IS Years Prior to Death CHEMICAL RFM7.F7JF DIETHYL* SULFATE ETHYLENE DICHLORIDE EIHYL0E OXIDE VINYL CHLORIDE AIL CASES Percent Total Exposed 9 11.1 GLIOMAS Percent Total Deposed 8 12.5 CONTROL I Percent Tbtal Exposed 30 26.7 CONTROL 2 Percent Tbtal Exposed 23 4.3 10 40.0 9 33.3 33 42.4 27 29.6 10 40.0 9 36*0 44.4 js.i 31 31 32.3 26 o50*o JUm 34.6 10 30.0 9 33.3 33 30.3 27 33.3 Table SB. Proportions of Cases and Hourly Controls Exposed to Five Chemicals at OX Texas City at Least 15 Years Prior to Death CHEMICAL DIETHYLSULFATE ETHYLENE DICHDDRIDE ETHYLDE OXIDE VINYL CHLORIDE AIL CASES Percent Tbtal Deposed 9 u.i GLIOMAS Percent Tbtal Deposed 8 12.5 CONTROL I Percent Tbtal Deposed 26 26.9 CONTROL II Percent Tbtal Deposed 22 4.5 10 40.0 9 33.3 29 44.8 26 30.8 10 40.0 9 44.4 27 33.3 25 36.0 1C IU as at.c IM 26- i' 10 30.0 9 33.3 29 31.0 25 32.0 r ucc 053174