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MMicichhaaeell AA. SSeamnotorroollUUSS--CCoorrppoarartaetl3eM3MIUU 0S112222007 01:23PM 01/22/2007 01:23 PM TToo. cc bbecec `Subject Subject PhilipeHof BE Europe IMUS@IM-Corporate JpPDaohalilteleip.LpL_.eBBBHouactocoefofnn/nBfh/UUEosS-f-Ef-CCuUorSoro-prppCoeoro/rar3atpMteeo//rU3SaSMHt@ A/aULS3SSMM@@ II-UCM3S-Mo@CrI-poCMor-orpCarpooteorrrapaoltreeata John L. Butenhoff/US-Cerporate/3M/US@3M-Corporate Re: Re: FFcw:: CConosidnerastioins ofdorrcecoonndrudcutcaitinngtg aaiPPFFoOOAAnaavvisiaann rreepprroo sstuuedyyD~) yPPohhiuilrliippeppaeer,l,ioeorvveenroraatlelll: I "aapmomssffiiinbniegliwwtiyitthhoftthfheieandarirgngguumrmeeepnrntotsseyfyofoeuucthhsaawvvheeerrnaaiiscseeodnd.d.uTTchhleeinoognnlSlyy oounnaeesttcthhuaadtthyI|.qquueIesssthtiiioosnnwiishsatththeeyaoonunee iinn `mymcoeeouaamrnpn,eo,uaoonrrrdlii.eisr tinttotthhthieaan:ttk"aatpnnhoiyysssrrpeeibhpprirlriaootysddeuuoccnfttefiiivenveeddsieenffg1ff0eerccbettespsrwrwoeooewuufolflrddedcbbetseed waatorhreeCnasepuctltouoronsfefdccutaauchpeptiintvpilvgioinytsty,u., ctthhhaaatt is not related study." Is this is not related 0 the what to the you compound. I think this phrase needs to be reworded to capture the point. W Wee ccaann ddiissccuussss bbrriieeffllyy alatteerr tthhiiss mmoorrniinngg dduurriinngg oouurr ccoonnffeerreennccee ccaalll,l. TTMhihkaaenn.kkss,, Mike MDMiiricechchtaoaerel,AAlE..nSSvaianrnottnoomrreoontal, Heal, 3SDSaMairffeeeEcttntyyoteara,rnnpEddrniRRsveeeigrgouSunelralmavttieoocnrreyytsa.AAl,ffffHaaieirrasslth, T3BBelMllddg:g.E.6n225t33e166r.p--71r13iBs83e--.116S003e7r4vices Fox:Tel: Fax: 651.733-1958 651-733-6374 651-733-1958 NiNonotttieiccneed::edTT0hhibisseee--ammparialii,lv,aiitnneccllcuuoddmiinmnggunaainncyyataaitttoaancchhoeenddlyffiiflleoerss,,thcceoonnrtetaaciiinnpsiseniintf(osnr)mnafatiomonetthharaabtotmvmmea.ayyabIbefetcyoocnuofiniadfriedeonetnniontatilaa.l.n IiItntitssended irrineetcceininppidieecenndtt,,altopnpllyuebeaeaastsdaeieapnnciorohitvmtiinaeffytynettghhscee.omssTeemnhnudedeneruircnaiiammtuimotmenhedoidorainiatzlyteeeldflyyorreaatcnnheddeipddtre,eelclueeisptteeei,eonodrrti(sddse)sesesntmtairronmoayyettitdhhoiinass,beeo-i-vmmseata.iiilblIufaatynnioodduna,alalllrocecfroopnepiopieetrssaoonofdfiuinti,tct,etnidoenfd Ptiihhnisiclsliueped-p-imemnagaHiilOal NnooryBr Eaaann-ttyyEacupphraamrro[epoonefft3sifit.,V. IiisTsUhNnSOeottuppneearrummthiitotteredizeaadnnddremmcaeayiypbtb,eeusuuern,ilaadwwisufsulel.mination, distribution, or reproduction of Philippe Hoff/BE-Europe/3M/US HPPohhiHillIiippBppEee.Europe/aWUS HofflBE-Europel3MIUS 1011/5152/20000770033::8400 A20M0 To To DMMiliccohhaLaeBclAaAlc.SoSanan/ntUotoSrrCoo//oUUSrS-CpCooorrprpooarraatttea/e3I/MMM/UUASS@U@CISoM3r@Mp-oICCroMoarrt-ppeoorraattee JDaolhe LnL_. BBuatceonnh/oUlSfU-CS-orCpoorrpaoter/a3tMe/SUMSI@US3@MI-MC-oCropropraotreate John L. Butenhoff/US-Corporate/3M/US@3M-Corporate `SSuubbjjeeCccCtt Fw: ConsidfrecorndaucttiingaoPnFOsA avian repro sty Fw: Considerations for conducting a PFOA avian repro study Mike, Dale, John, Mike, Dale, John, "sTtThuhadaynn.kk Myyooauuyf|fooarsyykoouuyrrouIinnfppouufttooounnrtthhieenaPPlIlOaasSKtHicCosSnEEuutrhro0eppaeergggurrmooeuunpptSasUtugigRogEneSsbttiioonnessS1too0lcctoohonnadd|uucwccttanaa sPPhFFarOOe AAthbbeiirrsdderreeapprrrgoouddmuueccntttiioosnnin w1ws0triutitdhninyegg. oMwwnieaittsyhh ImtthhaeeesnktPPilyloaaonssuettidifcocsrisEnEymuuoryruoornppofeeitnggearrloobuOuepplK.o. woBB,naasttshheeaetdd: on our con callof 12 argumentation below on our conf call of 12 Jan, | noted so that I can Jan, I noted as arguments in acdion share these arguments in as arguments in addition to the ones mentioned in my note below, that: iteitmwwbooauurllkddinmmgaakokene smmouorrceeahsseepnnrsseoe t1sootuccdooymm.pplleettee tthhee PPFFOOAA ddaattaa ppaacckkaaggee oonn aaccuuttee ttooxxiiciityy ddaattaa ffirisst bbeeffoorree ther areethical concelinnksed to embarking on such a repro study. there are ethical concerns linked to ttesteingsoonntvveeritrteebbnrraattgeess.. Exhibit 2727 2277227..00000011 3IMM_MMNNO033443366992244 I wililll aadddd tthheessee aaddddtiitioonnaall aarrgguummeennttss ttoo tthhee oonneess|I hhaavvee sshhaarreeddwwitithhyyoouu iinn mmyy nnoottee bbeellooww.. BBeesstt rreeggaarrddss,, 3PPhMhiilliEippuppieeoHHpOOeFBFMFFEA EHSER Specialist H3HBMe-e1mr8mEe3sue1risolDoapiaaeenn&gM77emEA EHS&R Specialist TBBBee-el1l:lg8gi34iu31um2m.D2ie7g2e2m48 70 TTTMroeribilmmi:ilin+ene:3et2.t:+23887233222427224844888887771000 632 MFFEa-axmox:ab:iill++e:33: 22p+h322o277f224f722@844m55m88m111.44 832 com E-mail: phoff@mmm.com ..... FFoorrwwaarrddeedd bbyy PPihiplipppoe HHooNffI/BBEE--EEuurrooppee/r3aMM/IUUSS oonn 1155/0011//22000077 1100::3344 --..... PHPhOhiHliliIippBppEee.Europer3WUS To MichaeAl SantorolUS Corporate MUS HofflBE-Eu[opel3MIUS 2112008-- 10:35 23/11/2006 10:35 To DJMDioiicehcttnhriiaccLeh.hl BASSui.inlnSnneaaanoeetvhoveore/oBll/UEBiE-SUE--SuCE-rouoCrrppooeopr/r3eapM/toeMS//Ur3UHaSMStS/Ue.S DaleL Bacon/USCorporate/MIUS John L. Butenhoff/US-Corporate/3M/US Dale L. Bacon/US-Corporate/3M/US Subjectcc Subject CCoonnssiiddeerraattiioonnss ffoorr ccoonndduucctiinnggaa PPFFOOAA aavviiaann eresptrooststuuddyy sTTthhueedy.aattttTaahccehheeiddntdderrnaaftfttsddtoooccduuimmsteernintbtuctcoeonntttiaasiinndssoppcrruoom//cecononnt aaarrmggouunmmgeentnthtsse ffPooIrraccsooinncddsuuEcucttriinongpgeaaAPPFFPOOAAaFdaavvhiiOaoannc rr1ee0ppxrrogorddouuuccptt.iioonn d`smitmuesecmcmlyubb.seesTrrehssdesstooinhtttheihnasoattatSiasoggtmorroeoduuieppsxttrddieebencuctiitssewiiioottnhnhisccJaaodnnhoncbbueeamnmmdeaandDdtaeealmoo.nnonwwGghheHetthtthheheeaPrr ltoatoswctcaiocosnsndEdbuuueccrttotipssreuunccAohhtPaa1F0Ossptturuadeddsyyehoonofrtcnntotohlo.te.x|cghIornhaosauvivdpeeerations. 1otdpo1ristotchhbueeasbggslreyroodunuoppthtaiasbssitoppnrrsaoso//ccmoonenussa.e.xwc|ItieaanltlshsteoownbbiteehdlloiiJeceovuvhemenettnhhataan.ttdss|oDoammamleeet.aahIdi~fdnledkiliitttniootghnnaaialntl ipaatarrwrggtauuismcmuebelnaentrttstsaebrccooonuuoulltddttohbbeeepfraaoeddlslddeoeenwddit ntbbhguuett these should considerations these should probably not be in such a written document. I am thinking in particular about the following: phoishsgigihhbiccolosstttyooofffbbfiiirndrdirrenepgprroroessptrtuouddeyyffects when conduciing Suasctuhdy unfSpuatnouvfsdaosyviubowriuilaitrtyahbblfolaeefvfipopnouodlrltiiantiibgcclaaelrleoccpullriimtomcaaeottfemefeeaacrwrtsooounuwn'nhdtdeppnpererocrfbofllanuub~oollruryocachtcihanhevegmemsiiauccacbalhilssgaiiinnsmtggpueeadncnyeterraallssoo hat that the the impact impact ofa o1' a bird bird repro. repro polfspiototurlidiatciyucanawlolirtpphirrseefaasstvssiouuorurneerauoonbnndleePProFFuROOtEcAAoAmwCwiKeilll,wmmroooesnsst'tpt pepprcrrootobbibaavabbebillyyoyftl1heheaaaevddetatooavaPPLl)FFiagOObii/mA~lpyaaassocftaaa""ssPuuFbbOssttAaannbccieerdoorffeeepqrquouiisvvtaaulldeeynnttwccioohnnccaeernn"" fffboaayrvvPooauuFurrtOaahbbAollreeitshaooeuutitoptccrnooemmsuesne.ud.reNeNrootRowwEhttAhahaCvaetHi,PtssiFreerOeeeAsmmpssaesctththaiaavte"t sooounnfbllysythttteahhneeacv"e"aPPoiTlfTa"ebqppilauaitrirytvt aooolfffea"`nPPtPBBTcFToO"nwcAwielirbllnirbb"deericcesoopennrvsoseiidsndteeuhrrideegyddhewftroo.ithbbeea mmeett bi0bnroydPppaarFrertOtpiircAcouultlshaatreruccdpooirnenesccseesarrurnnareoonftofotaauuhbttaehhvooderertifPtiaieeFusslOtaaArbbeoaoqusuuttiarbbei"idrsrdduu/bA~nsPdPteaFFrnOOceexrrieesopptfrrioeongqeeufcfffihveeeaccmtltesisncat lcolnegciesrlna"tioisn even higher. applicablteo PFOA andbird and won'tbydefault be required under REACH. repro studies are not be default required under won't by default be required under REACH. existing chemical legislation applicable to PFOA CCoommmmeennttss aarree wweellccoommee.. `[{aSattatatnacichGhmrmOeeUnnStt-""Cccooornnpssioiddreearrtaaett/iioo3nnMssUSoo]nn ccoonndduuccttiinngg aa PPFFOOAA aavviiaann rreepprroo ssttuuddyy..ddoocc"" ddeelleetteedd bbyy MMiicchhaaeell AA.. Santoro/US-Corporate/3M/US] BBeesstt rreeggaarrddss,, 3PPhMhiilliEippuppreeoHHpOOeFBFEMFEA EHSER Specialist 3M Europe&MEA EHS&R Specialist 22772277..00000022 33MM_MMNNO033443366992255 HH6e1em8rme3se1silDaaiaaenng77em TBBBee-el1l:lg8gi3+iu1u3mm2D2i7e2ge2m08 70 TTTMroeriiblmm:iilin+na:3et2:t:+238872332224.27224644888878770100 832 MFFEomaxoxa.b:iill+3e3:22p+2h327o272f242i72@484m55i88m111m44 832 com E-mail: phoff@mmm.com 22772277..00000033 3IMM_MMNN0304334639629626.