Document a4v6aL7GJo78zDk7qj0g04kj9
DEPARTMENT OF HEALTH & HUMAN SERVICES
Public Health Service
Center* for Disease Control National Institute for . Occupational Safety & Health Robert A. Taft Laboratories 4678 Columbia Parkway Cincinnati OH 45326-1998
June 3, 1987
Mr* Peter L. de la Cru* Lev Office* of Keller and Hechman 1150 17th Street, N.W. Suite 1000 Washington, D.C. 20036
Deer Mr. de le Cruzt
We vrote to IARC In Lyon, ** ve hed Indicated, end received e reaponee from Dr. A. Aitlo, Officer in Charge, Unit of Carcinogen Identification and Evaluation. A copy of hie letter la enclosed.
In response to this letter, we have changed our listing* in the Registry of Toxic Effecte of Chemical Substances (EXECS) to conform with IARC criteria. In fact, we have reviewed all IARC citations to bring them Into conformity with the IARC criteria defined in Supplement 4 and subsequent monograph*. We now uea the IARC terminology of "Sufficient Evidence," "Limited Evidence," Inadequate Evidence," and "Mo Evidence" of carcinogenicity.
In view of the IARC letter, end also applying the criteria, the SXBC8 record for polyvinyl chloride nov carries the following elections:
IARC Cancer RevlewiAnimal Inadequate Evidence IARC Cancer Revlev:Humen Inadequate Evidence
I regret that this whole process we* slow in reaching a resolution, but it did raise an issue of Importance for ub. Tour Inquiries helped ua t focus on our need for reviewing older citations. The criteria that IARC now uses simplify our task in reporting the conclusions of the IARC working group* more accurately.
Sincerely yours,
Enclosure
Doris V. Svset Editor, BTECS Priorities and Research Analysis Branch Division of Standards Development
and Technology Transfer
BR 005275