Document a487qg3w87kJ88KVBY6oGrDJB

V '= \ Oa'feba Bffoofes t Sapean** fe fcbe t m t o t Sagls?lofcer tnsulafctag . fSafesrlal Rotearfe A* Esti* 13D* and W lllerd F# tctil , M*S* Xha a ctu a l oathode aployad la lasulafelng basaos wlfeb Sha &ype o f poo3fiool aonuftarad by (Su &8Xo~P$bs* load Qon^aflqf t o * ofesoraod by vtsifeing saaeral alte afc whleh fchta aasfe ma in pragreaa* Saos tria ^ayying anafe asposur oaaoelafead wlfeh d lffe r e n t oparafeics and fcha preeaafeloaa feaketi ag&isiSfe anoh ep atar $*0 seas# 2fea nagnifendo til oxpoaura fea anafes la ttoa various paratiesas f a. Job la Oinclan&fei tsaa dsfesnalnod by soU ostiag; so r e le s o ais? la fcho Sasedilata u ic in ity worbassa* un&@r varying ooadittc^w and aafe&aafelag fea quantlfey ot ana pondo nafe# ' fa load eonbont o f a ana p a o eh inaala.fe.lns saatorlal nao dafeerolnad by apeatroggapbi* en alyaa la os?ar fe sale s a o s .sa tn a te f tu significan Sha load ttcpocniva o t feh norteas Xa arde? fe observe the affGOfes o f m a sa apostara fe feh dusta o f fehe insnlafelng m feerlel m greop f a s * er s lte te * fo r exealna feln and afeady fro a large'greap agoged in inaulafelg b a ild in g s* Tha seisfeln na m s la b ia t lo n fe tha langfeh o f etaployaenfe o f non groupGd in oslas ora In v areos p&rfea o f th e euixtrsr* Fresa feh ava* la b io Informfeton# a h&vm in Tabla X, Ife asa &ppartife felmfe feha gron? In.Basfe aran# Se Jersey# had boan aployad len g est* ubi la feh largos fe greup la any ono Xoanfeo, and# therofaro# tbe on sioat ro a d lly * 2 -. ** a cc essib le# m s situ a te d ab m it P lain s# Connecticut* Thm& t m groups esobined could bs expected te provide v a r ia b ility of ssp osare in clu d in g t o g r e a te st Which had oeotirred# sad sin c e sime o f feos who had been Isi t o s e groups had discontinued t o wo &# t o r e bad besa no fa c to r o f c o le e tir e o l i a t o t i on* t o d l t a y ores happened to fee employed tem porarily in White P lein s a t the ttn e .of tb s esa s i aafeou o f the ia lite Plais groap* T heir In clu sion brought th e to ta l number &t m n sssaiood up to tBCBt^sevesi* fo to d a * .' Duet assopite m m o o lleo to d in th e a t t ic o f a house in process of being in su lated # la r e la tio n to both ha&#p&eking and blowing* samples were a lso c o lle c te d a t th e a ir pusp used to blow t o in su lation * She m odified $reenbuy@*Sait$i Incinger was employed w ith the standard U aaM rivm t auction ap p arato* The technique o f c o lle c tio n # handling and counting mm sim ila r to t o t described by Bloom field and :D allavalle CD* . The oam plets h isto r y o f d i previous and p resent employment .and o f p rvien s H in c a s mm recorded fo r each, man# togeth er w ith h is ago# h is fam ily h isto ry # the gen om i s ta te o f h is health# and the presence or absence- o f sympbs o f l i t o t e or organic d isea se* S p ecia l a tte n tio n oca given to t o duration o f th e p resent employment and t o nature o f th e day work# w ith referen ce to eep otcee to d usts o f insula* tin g m ateriel A eeisp leta p h y sica l m s m tm tlm mm given each m n# in* eluding t e s t s o f the sp e c ia l sonsos and -of muscular power# a n a ly sis o f the urin fo r i t s rea ctio n and fo r albumin and sugar# and a m icroscopie study o f t o blood* That la* to say# a thorough search as made fo r any and a l l p h y sica l a i t o n t or eh n om ialltlee# t o s e observations were recorded on t o fossui reproduced in fig u r e s 1 and 2* A s a je le o f b leed and te c samples o f u rin e were obtained , *&gh oea in ehoiaieally loan ooatelnera propers*! 1n the laboratory, ooro returned to the laboratory fo r an a ly sis* th e Blood end on ra*t f1t3 am* s Si <3 s I0 I 4$1*4 4o3 m2 43 c *ar4i Oos $ Sr1*i >*fij0 <sOps*i. W H0ES as *e? e 2? ''i & a oa0"!`l 3rO-3t 0 O E& K3 So gi fi Bi 4c,>- fHt f0,,i og * g* b 0B fo, |- u 43 *8 8| *% e 1I 1*4 4&g3 0iSs a1> J0S S*i Hi ,pc, a ft* 3 4CO33 533 \ \ *k* mu mmemployed In blovin g operations unions due precautions taken# S danger o f heavy n o ta i poisoning sould be sconti a t those d u st conoontratt ana* I f there ero s ig n ific a n t q u a n t!ties o f such n o ta la In a so lu b le sta to In the tufttcrlsl Even r e la tiv e ly Insoluti ompounde o f 1m&9 fo r example* sou id be p o te n tia lly dfi&geraus* Hare* however* xm arc d ea lin g in son measure w ith h y p o th etica l a tto rsi, such as the proportion o f s to r ia i a c tu a lly in haled as compared w ith th at svalleaed * as ell as i t s s o lu b ility and a b so rb a b ility In the lungs md la the alim entary t r a c t . I t seemed beat 'to d osi v itti thee m atters p r a c tic a lly mm mth ro n g the study o f th e eapooed rather than by methods based hypotheses* Hovever* the to ta l lead content o f tv samples o f 'the rock* v o X m a determined by an a ly sis# A a m p io o f m aterial such as i s put through th e b lovor shaved a -len d con ten t o f l#12$* vhll & a m p io o f fe a t packed by hand was 0#9^$ le a d . Arseni de te rm in a ti cm or nob mad kocauss of te ch n ics! d i f f i c u l t i e s duo t th e u n ta re of th e n a to ria l# irfe s&cfc e x p o s i t i o n o f fee rock-wool v i l i b detenainod a t a la te r date# ih spefcregxvsa'which ver# taken t measure lead q u a n tita tiv e ly demonstrated th e presence o f la rg e quantit ie s o f Iron* appreciable quant! t i c s of alu sstn im and manganese# to g e th e r w ith tra c e s o f copper ohraeaiua n ick el and t i n . . TB*' in fa#Won obtained from the semination of each m q m vmwas considered f i r s t unit* In a as there o lic io a l ideas mme f assy occupational I lln e s s os? dissas # So' s s a i l l or complaining vaguely f g en era lly poor h ealth # I sa had l o s t voight* ap p etito or atrengtk* or was Hhsr aay combination of symptoms or p h y sica l sig n s su ggestivo o f silicosi : or f Xe&d or arson! p oison in g. Hi# only ccEtsiou involved tts te e th and gens and fee upper resp ira to ry tract# sev era l sen had com e cold s in various sta g es and most el* th e e shoved some degree o f redness and ir r ita tio n o f the m cous mes&raaes o f . & & tr>i *4 aS 8 t i 8 l " # ce* I! m * S s a -I <Hf tmrit r* S **ash* * *%8 *_og. fi aa a 1 1! i OG* e 5 !s cH H# Se e i t *4 * pai * <H tfit S If* I* a a> 0 5 h 1 1 S B i & * ,f? tGo AegH < $ tri Usr*i % H the m m m piat* only a tm had good tooth m. clean healthy guets* Iloscver, despite the frequency of dentei caries and spongy, congestive, under study rep resen t a rather eid e range w ith resp ect te ticr ago In ta b les 4 and 5* the v a ria tio n I s s y s to lic and d ia s t o lic blood pressure of the group i s shown* (th e c irc u la to r y cyst shows evidence o f impair moat or abnormal fu n ction in n est co ses o f chronic or s*abacutc in te sio a iO, S A8 <_U* <u e g B * B3 II 40 Zm $ 3 g Si I g 4 i 5*0H>4l 56 oFOn-4 ,mg D, *4 0 fb fi 0 1 M tH* t ! 1 C4S en fi tilos* and for tihafc reason any unusual trends is blood presauro are of infortiamo is group stu d io s of teala sgontio) of tbs fir inataeos of igiflantily falgfe eystiolie bloM pressure* four were lo pofsons oros? forty yean* of eg 'Shs on rather los figuro (100) osoiunred in sa m& d is a b ility # or other evidence o f in fe c tio n In. the fo m o f suppurative g in givitis# ' Tables ?* # and 9* g iv e th e r e s u lts o f the study o f the eryth rocytes (rod blood corp u scles) o f the blood# ' inasmuch. ns lead absorption tends to causa m in crease In the am ber o f *otlppled* aiyt&roeyfces# and a la te r decrease in the t o ta l ntm&er o f erythrocytes# together w ith a drop in the hemoglobin o f the blood# th ese observations have a d ir e c t bearing on the q u estion s o f lea d ebaorption In those men# The one la eryfshrecyt ouhb o f 5#ls.S0#0O0* as not aeomapanled by other evid en ces o f abnormality* the -hasoglehia Value in th is ease being v e il w ith in normal lim its# The r e su lt la not e f p h y sie io g ic a l sig n ifica n ce# therefore# A ll the hemoglobin determ inations (Ib w instrum ent) gave r e s u lts 1 th in th e normal range* The study o f the s tip p lin g o f the erythrocyte*# llSmrarlse y ield ed normal r e su lts* O bservations among large numbers o f apparently normal persona o u tsid e the lead trades* mode by the methods used In th is study* have been reported elseeh ere (4) and provide a b a sis fo r th e in terp reta tio n o f th eee fin d in gs# The one r e s u lt o f -14.0 stip p le d s^threaytee per 50 m icroscopic f ie ld s I s unusual# but such, value occur In e n tir e ly normal end h ealth y persons# d l l the other r e s u lts are s e l l w ithin the cm ternary normal lim its# The a n a ly tic a l r e s u lts obtained on the blood and u rin e mm recorded-In Tablet* 10#11 and 22*. The q u a n titie s o f load found in the blood o f th ese men cover . range o f v a r ia b ility ouch m has been reported p reviou sly in a group o f normal h ealth y students <5)'* There I s no abnormal r e s u lt in th e e n tir e group# Tho an alyses o f the u rine fo r lead d e e y ield ed r e s u lts w ithin tbe normal rang as p rev io u sly defeemlned fo r la rg e groups o f norms! persons ($ ){ 6)# I t la quite certain# therefore* that the in halation of the duct of the ainoral*Moel has not r e su lte d In m appreciable lead absorption on the part o f these men# Hu* a rsen ic determ inations on the u rin e are su b ject to s t a lla r Interpretafeto * ' Bfe panga' o f B oreal v a l es fo r upinary raenle la nofc &u XI esfefeXiehed m i a fe m m o f lo a d , b at fe mean exeroticfn o f a llm lfe d aoufeer' o f s t t a l persona.has m fcav afe&ied orreaponda to fe&t eetlsaed Sa tM s grenp e f saet tb e alar PoXafcXvoXy .hlgb p oeu lts (1** 0*0 suso* o f %03 p mop. pr U f e r f tipia) abe* a ooprslafclon e ith tii Mgfeer load fia d toga* p tfe lse daratton r e^parent aevorlfcy o fe s oeeupaetoael. expoaupo The; say f e pegerded a pande reau lta uareXafed fe fe oeNaupation. '' Tm esaatn ato o f fe :&*rey f i l m by fe fereo radiologafea reaulfeed la . fe general. agreecmife fe&fe'tbene ero a tatoosferabl* pafeologi .roooGoea op deposita wMoh oouXd eopfcair&y b afeferibufeod to sacupatl^im l exposuro to duafca* l a oeveral eaaee- fep@ % s m dlaferlbufelon of flo r e a s feangea suggeafeive e f IsoXpionfe a lllo o s le bufe f ann a ta o r oharaotsr aa aofe to fe oorfealBly dlffepentlAtM d fresa fe aeoendagy effeofes of ohronle p aubaeate upper respirafeory iafeofeion# Gao of fe radilos! con su ltante ospressod fe o lr Jolnfc o p in i n , fea fe fe *Xsioas ara aere onaorous le fe l group of aea febaa e se erd tn a ril? see e la sim ila r raesber o f adulfe boafe fila s !2&svr* fcher b eta s a saaXX groe? wb bave nono ****** to spoak of# ose auftt pender hefcher r .fe bisa, fia d Inga aro o f sig n ific n o s X co not so how m aa b s m * ** tmfetl a eeaaiderabl* t im In terra l bao elapecd cud aaetSkar serla f fllssa {hm baos) ;sae <m fe ssaa greup o f sea ~ - X-eeaeuap la 'fe eo o elu sleii feefe netbing bae fea feund 3aili can b atfePRfttMgA fe Mi in d u str ia l fso fe r o to o l^ fe ** X. Bi sefchodo asad la tenutatlng- fe lld ia g o i f e Jatule-Piobop rock so o l tavotoe 'eeeetdepeble esposo* t o duafe r ls in s fpo*a fe jsafeptal* Bao hand packlag operat i oa oao soen fe p o o u lt la suspendas sessewhat le s o fea 500#0OO daot p e r tlo le o pop ubis fo o t t e f e fe alrji in fch lrtdate . v le ln lf e of feo operating puaip# fehe p a r ti le s sm borod a p p ro slm fely 4 Uch m 8,OO0#OO p a r tia le s per oA Se Sont 2* Tim a&fcaro o f fcho a a t e r la l'te mm& as b suggost. bit p o a cib llib y o t a s i l t c o s i s hasard* iaa content (opproskeatoiy i* fch s ilic io * nafcorlal la o f d a u W t g^ ifiteu ie b3seeretion? Ilia . oreone cocfeemt ims not daterai nad 3 sfcmdy o f 27 mas f foa a vmto#* ^ w i te tsor tfca fo a r yfters o f or? mro te buste in b astiog fci in a u la tln s m fcsrlal* fa tla d t ho acy tn ie st Tidenot or occupation! dlaecs or llln ea a * lu sfcudy o f fehe Xoad aa am ante am aattcn f Staea non d iscloaed no itenea o t absorption f laad or arsonte 1 Quanti tla s abovo thafc htel*. 1:33 boe shomi to oeour cessons al- partut n iteo n t oooupatioaal spcau `J n&dlographie ehejit s&teationa atmmtA a ertaa ^ridons of o- '.national plnmarjr dteaaae asoh a oaur la aararo ospoauro ta a iilo a # `fharc aaa gsaabite avloaoo o f th dovotopmnb f pulaonary changea* but th vidente eue not sa ffio isn fcly iwineng fco- j u s t lf y a dlsgaoetai of 'oarly e ttto o a ie ta aay cas# -' foforoac^g 1* Sieeesfilel* J*J* and Danamallc* 3*M*$ U# 3* Pdblte B eelth SaXlofetn- 3* 31?* (1935> 2* Oholak# bf Q a ea titettre apeeteegraphte teteaain ab loa o f IJad 1 B io lo g ieo t M ateriel* lad# ad Sag* Ofeesi** 7s 2^?* (3*955) 3# Cinalngs Bonald 2* v Saate tsi Afcrseepteref abhes o f Eafetsafelon ad 8Igiiean eef teeo&d Bympmi^x. a S ille e e le * asplograra iSatesI X&aur&nee Cosapany <3.955)* . ' lu Xfchoe* 8hert mt Ttm Dte&noet* of lead ?isatg ta tbe Liglit o f B m ont Xnfo&Bebi* Jour* o f tid# (C inotm ;ti) 16s 52?# (1955) 5 Bfthoe 'Hofcert a 9$ fhmsana, Prsderlk, aad CTaotae,, Jacobs nonasX Vbsorptttt<o and Escx^tlea of hm.d0 J Am HA* loi}g 90# (1955) 6# Kehoe Bobert ## bsnaim# Predcrlok# and ChoXak# Jacobs Or. tti Lead ssoftfefetd its W&m Ssm xlom Life* J* Induafc# liyg m *w m . \( 0003004