Document a473kMv5RLEaV3MMOY19yG5BN

y.; ce: Meiiara, 48OCJt*..rdFM....BKHKleeiihrbtebsoaeyerr`: CONTACT REPORT R. Reales v K. Svariwocd P. Weiner 3u'ect- MMMBnMM Zeiephone Conversation with. ir. DeFrance Clarke, Assistant Manager, Fine Chemicals Divioion, Union Carbide Chemicals Company Jev York, New York January 3, 19 58 fmese -f Cal*. A cali as made to Kr Clarke for the purpose of t V* . ' ' . ' . -' . " _ . ' . . ,-. ' ", ' 'j' -U 1 . Checking the statua of Carbide's work on preparing a (flotation Cor suppiginj us with orijanomaa^aese compounds. V,.- ; ;. . Informing Carbide that Ethyl's patents claiming AP-3 and AP-30 an codecs; Lens of natter have issued . - a . - . ' utatup of Carbide's 'Cork - ..... " Mr. Clarke irjdicated that Carbide la nearly ready to discuss their ,;rcpc3itica for supplying us vith Grgaujoraaaaaaese compounds. He Indicated tnat he ni^it like to visit with us in Baton Rouge the latter part of the week if January 13 if their studies arecompleted. 1 told him that this: : jouxu be cext-sfactor* with us and we should be glad to discuss their studies with tuea at that time. . . ` '... 'V. ....7 -r''t Mr. c:.arke said that Carbide is still only in the laboratory scale 1.; the production of AK~33X**type compounds. They are still hesitant to send 3 camples for testing because they are not sure they are yet producing coo pounds which Will be representative of their commercial product* He said he vouii check with his organisation to confirm this* I f he found they were , further advanced, he would send us a cample. : Mxic' .epical Properties of AK-33X Mr. Clarke asked if we were concerned over the toaleologicefc^^ ; properties of AK-33X. I told, hi that we had at least'another''two voris tc do before we could set qua&ttative standards for tolerable 2 J a d t * 0 0 $ i ^ AX-33X compounds. However, preliminary studies completed by Dr. Keboe have `-pi indicated .that the materials should be no more hazardous than tetraethyllead:'^ ana that them. their toxicity should not constitute a barrier to our marketing V'.-"..-: U 'vV,'" ` aWr's*trf:"-:' Mr. Clarke said his concern steamed from the fact, that'data Carbide had accumulated showed that inhalation of IOC parts pay m flUaq of. y V the MCF derivative (AP-3) killed six out of six test animals. He said.that ,p ;*e aid ;ct have a good datum plane with which to compare this, but that t h e ; ; j~ata ca sed ais some concern. He said he thought that these data had already* vi ; been 33.t ur. Kehoe. He will check with his organisation to see that , \t .i Ihe.v are they have not already been sent. . il Status of Our Program la response to Mr. Clarice's questions, I repeated for hi the status of our program. X informed hia that we are still on schedule cn our cartet survey and application studies and that our process development projrraa 13 still reared to comaercializatioa la early 1'560. I told hi we were still open-minded on the relative aerita of the C? and the MCP deriva tives. We are engaged in application studies on doth compounds, and it is stili. too early to tell which is preferred fro the overall standpoint of effectiveness, digestibility la the engine, and availability of raw materials. Mr. Clarke asked when cur anoageiaeat was going to make its decision on whether or not we wanted to market cur new antiknock. I told ain we had already crossed this hurdle and that we are planning to sell it if a narket is developed. Ethyl's Patents I irrformd Mr. Clarke that Ethyl's patents, lumbers 28l8bl6 arid 23l$kl7, claiming aF-3 and AP-33 as compositions of natter have issued. I agreed to send him a copy of each of these patents as soon as they are received. 28lSklo claims broadly cydo-pentadienyl aetal compounds of a rare gas structure. 2olS^17 claims AP-5 and AP-5Q specifically. PAM/3 1-- 7--pS .1* McKin K f 001S 324