Document a1pOVKYN05gqoQyRv400N2R99
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PERSONAL AND CONFIDENTIAL
AR226-2852
Copies to
E. I. du Pont de Nemours and Company Haskell Laboratory for Toxicology and Industrial Medicine
HASKELL LABORATORY REPORT NO. 825-76
MR NO
Material Tested
Results: Dose
0.1 ml undiluted test material 0.1 ml undiluted test material
Haskell No. 10,642
Sample Ready for Testing
9-28-76
Other Codes!
EYE IRRITATION TEST IN RABBITS
ss
Material Submitted bv Organic Chemicals Depar ment, Chambers Works
-
Treatment of Eyea
Not washed
Washed
Cornea
Ocular Effects Iris
Conjunctiva
Small area of slight opacity 1-4 hours, receding to localized microscopic surface sheen at one day.
None
Redness: Mild 1 hour - 3 days. Swelling: Slight 1 hour - 1 day. Discharge: Moderate 1-4 hours. Hemastixposit|.ve at 1 hour, slightly positive at 4 hours.
Localized area of slight opacity at 1 hour.
None
Rednegs: Slight 1 hour - 3 days. Swelling: Mild 1 hour - 1 day. Slight 2-3 day Disctjar^ie: Moderate 1-4 hours. Hemastix- || positive at 4 hours.
Sanitteed. Does not contain tscacbi
Compaq
2- -
^H!5SZ:l j H H B ) )roduced a sma11 area of Slight corneal opacity and mild conjunctivitis with no iritio affD,,t <
rabbit e > . Corneal opacity was reversible and the eye was normal within 7 days. An^eye dosed with the c o m TM
a
promptly washed had transient minimal corneal opacity and mild Conjunctivitis with no iltic effect The eve
i
within 4 hours except for a persistant mild conjunctival irritatioi which was normai w i S n 7 diys"'
* n0nnal
Although only temporary mild ocular effects occurred, good hygienic practice would be to final,
i
water after any eye contact with this material.
practice would be to flush copiously with
DFE:ms Report No. 825-76 Date Issued: November 5, 1976
Report by: Approved by:
Doris F. Edwards Toxicologist
CfJ.'i'k&'/i&n)
Raymond W. Morrow Chief, Dermal and Ocular Toxicology Section
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