Document a1kDgEKzj254rBpQoO920Vg6N

FILE NAME: Oil Industry and American Petroleum Institute (API) DATE: 1950 Nov 10 DOC#: API014 DOCUMENT DESCRIPTION: Meeting Minutes & Attendee List - API Medical Advisory Committee For Infermati or. Only - Not For Publication AMERICAN PETROLEUM INSTITUTE MEDICAL ADVISORY COMMITTEE TWELFTH MEETING Minutes of Meeting November 10, 1950 Biltmore Hotel Los Angeles, California CORRECTED PAGE members present Kieffer Davis - Chairman B. B. Reeve - Vice Chairman Marshall Clinton - Secretary V. C. Baird L. E. Curtis T. M. Frank A. E. Hoag T. J. Kelly James W. Long E. F. Luongo M. N. Newquist R. C. Page (Rep. by T.E. Allen) Chas. A. Swan E. Richmond Ware MeIver Woody ASSOCIATES PRESENT L. C. Beard, Jr. J. S. Boylan R. C. Cole R. W. Faulk L. M. Henderson (Rep. by R.J. Askevold) J. E. Hill R. M. Landon H. P. Lankelma (Rep. by F.J. Sanders) D. W. Larmer (Rep. by C.K. Hewes) K. G. Mackenzie R. M. Shepardson H. D. Wilde GUESTS Richard Dillon - Standard Oil Company of California, Lbs Angeles Philip Drinker - Harvard University, Boston R. E. Eckardt - Standard Oil Company (New Jersey), New York Charles Henri Hine - Shell Development Company, Emeryville A. W. Horton - University of Cincinnati, Cincinnati Robert A. Kehoe - University of Cincinnati, Cincinnati R. C. Mlthoff - California Research Corporation, San Francisco John J. Phalr - University of Cincinnati, Cincinnati H. W. Prince - Standard Oil Company of California, El Segundo API STAFF D. V. Stroop Total in Attendance - 37 MEMBERS ABSENT W. 0. Armstrong F. F. Boys Wm. Crookshank D. M. English J. P. Holt W. R. Levis E. K. Linder Robert B. Lynn Clark R. Miller API 07064 ASSOCIATES ABSENT E. W. Adams W. R. Argyle R. D. Bent C. L. Erown C. R. Brora L. 0. Crockett . - 2- J. B. DeLaune T. E. DeVilliers Allan E. Dooley E. S. Driver N. J. Gothard COSEECTED PAGE E. W. Isom C. E. McKay C. A. Neilson V. H. Price E. B. Eoaper F. M. Watkins ACTION I MINUTES OF ELEVENTH MEETING The committee voted to approve the minutes of the eleventh meeting as circularized. II ' REPORT OF SUBCOMMITTEE ON CABCTNOGENICITY - DR. Me TVER WOODY. CHAIRMAN On behalf of the subcommittee, Doctor Woody reported five reconsaen dations for adoption and transmittal to the Safety Committee of the Board of Directors, as follows: 1. That the progress report of the fettering Laboratory be received as presented. 2. That copies of the report be sent to the British Institute of Petroleum. 3. That the work of the fettering Laboratory be continued and that the present scope be maintained under the supervision of this subcommittee. b. That funds be provided, not in excess of $100,000. 5. That, although publication of the entire report would be premature, it might be well to publish the standardization procedures, with a statement to the effect that too high a concentration of a carcinogen conceals its relative potency unless the frequency of application is reduced. ACTION The committee voted to accept the report with the understanding that the matter of publishing all or any part of the report would be more specifically and fully discussed prior to release of any information or statements on the work at fettering Laboratory. API 07065 - 3- Nctes: 1. Copies cf the progress report of the Kettering Laboratory vere circularized to all members and associates prior to November 10; therefore, copies are not attached to these minutes. Additional copies may be obtained by members and associates upon request to D. V. Stroop. 2. A brief summary of the Kettering project has been prepared by Doctor Kehoe. Copies were given tc those in attendance at the Los Angeles meeting and are attached to the minutes which are being sent to those who did not attend the meeting. Extra copies may be obtained upon request. 3. Copies of both reports will be sent to members of the Safety Committee of the Board of Directors and to the General Committee, Division of Refining. HI REPORT OF CONSULTANT - ERCFESSCR PHILIP DRINKER Professor Drinker said he had no formal report to make but wished to remind the members that he is serving as consultant on industrial-hygiene problems and as such he will be glad to attempt to answer reasonable questions received from members and others cooperating in the work of the API Medical Advisory Cosmlttee. He expects to attend both the annual and aid-year meetings of the committee and to keep committee members posted on MAC values current or suggested by the various agencies concerned. He or his colleagues will be available for a limited number of brief plant visits and inspections upon payment of travel expense by interested companies;, provided, of course, that any prolonged studies or extended plant inspections would have to be especially arranged to cover costs of services as well as travel expense. Note: For convenient reference Professor Drinker's office and home addresses are recorded as follows: Office: Harvard University School of Public Health 55 Shattuck Street Boston 15, Massachusetts Telephone: LOngwood 6-2380 Home: 12 Hubbard Park Cambridge 38, Massachusetts Telephone: ELiot k-28l3 IV REPORT OF SUBCOMMITTEE ON PERMISSIBLE CONCENTRATIONS - DR. V. C. BAIRD. CHAIRMAN On behalf of the subconmittee, Doctor Baird reported that the final report of the API project at the Harvard School of Public Health has been received and sent to all members anti associates. API 07066 action T He also reported, two recommendations, as follows: # 1. That the Subcommittee on Permissible Concentrations, as originally constituted, bo dissolved, and that future specific problems be referred to specifically consti tuted subcommittees, as was done in the case of the Subcommittee on Economic Poisons. 2. That the attention of the Medical Advisory Consulttee be called to the fact that no provision has been made to review periodically and keep the Toxicological Bevieve up-to-date, that it is desirable to do so, and that consideration be given to the appointment of a Sub committee on Toxicological Reviews to consider ways and means of doing this. The committee voted unanimously to: 1. Accept the subcommittee report. 2. Authorize the chairman to appoint a Subcommittee on Toxicological Reviews. 3. To discharge the Subcommittee on Permissible Concen trations with a rising vote of thanks to the chairman and members for the excellent results they had accomplished. V REPORT OF SUBCOMMITTEE OH CUTTING FLUIDS - DR. B. B. REEVE. CHAIRMAN On behalf of the subcommittee, Doctor RSeve reported as follows: Inasmuch as erroneous or misleading information continues to appear in public press, it is the recommendation of this subcommittee that the members sond to the API material appearing in publications, trade Journals, technical literature, etc., on cutting oil dermatoses. That such -articles be submitted to the members of this subcommittee for review and consideration and they in turn submit same to the API Medical Advisory Conmittee with their recommendation for handling or disposing of such material. Vie also wish to call to your attention a letter sent to you by Mr. Stroop on October 2k, 1950 informing you of the setting-up of two sub panels of the Hygiene Panel of the Marketing Division. One of those eub-panela ia on Cutting Fluid Hygiene. The chairman is W. H. Oldacre. One of the duties of this sub-ponol is to study the problem of cutting oil dermatoses as it pertains to the petroleum Industry. API 07067 - 5- We have been assured of the closest contact between this subcommittee and that of our own, and as soon as they have developed a program it will be submitted to the members of our Subcommittee on Cutting Fluids for review and consideration and they in turn will submit same with their recommendations to the API Medical Advisory Committee for final action. ACTION The committee voted to accept the report. VI REPORT CF SUBCOMMITTEE ON FLUORIDES - DR. A. E. HOAG. CHAIRMAN On behalf of the subcommittee, Doctor Hoag reconmended that the Medical Advisory Coamiittee should include in its budget for 1951-52 an itom of $2,500 for continuation of the cooperative work on fluorides at Kettering Laboratory, but that the expenditure of the fund should be contingent on the continuing support of a majority of the other cooperating groups. (Copy of subcommittee report is attached as Appendix A.) ACTION The committee voted to adopt the subcommittee recommendation. VII REPORT OF SUBCOMMITTEE ON MEDICAL POLICIES AND PRACTICES - DR. L.E. CURTIS. CHRMN On behalf of the subcommittee, Doctor Curtis reminded those present that the subcommittee's program was limited to the gathering and dissemination of information from and to the committee members on subjects of mutual Interest relating to medical policies and practices. The specific subjects to be included in the program are based upon inquiries from members, or by committee assignments, or by consensus of subcommittee members as approved by the committee. Ee stated that the only subject actively handled by the subcconiittoe was the compilation of 19^9 medical-departmental forms. He recommended that this compilation should be kept up-to-date by an annual request for latest revisions on all forms. ACTION Ihe cannittee voted to accept the report and to continue the subcommittee. VIII IN APPRECIATION On behalf of the associate members, K. G. Mackenzie proposed that the Medical Advisory Committee should rocognize and express appreciation of the valuable services rendered by Doctor Mclver Woody. Ee preposod the presentation of a suitably inscribed and subscribed certificate worded as follows: API 07068 - 6- The Medical Advisory Connittee of the American Petroleum Institute recognizes the valuable services of Its first Chairman MeITER WOODY, M.D. and expresses Its appreciation of his Inspiring leader> ship as one of Its founding members and as Chairman of its Subcommittee on Carcinogenicity. Los Angeles, California Novomber 10, 1950 (Space for signatures) ACTION By rising vote the connittee recognized and expressed Its appreciation of the valuable services rendered by Doctor Woody and voted to record this action In the minutes and to prepare and present the certificate as proposed. IX REPORT OF SUBCOMMITTEE OH FIRST AID - DR. M. N. KEWQPIST. CHAIRMAN On behalf of the subcommittee, Doctor Newquist moved the acceptance of the following report: Pursuant to action taken at the April 1950 meeting of the Medical Advisory Committee, a Subcommittee on First Aid was appointed to review from a medical standpoint the proposed First-Aid and Safety-Training Course to be sponsored by the API. Due to certain objections to proposed awards and schools for Instructors, the subject was referred back to the Central Committee on Accident Prevention for review and/or modification by Its Committee on First Aid. In the Interim the Committee on First Aid, of which C. A. Miller Is chairman, has changed the title of the proposed "First-Aid and Safety-Training Course" so that It now reads, "American Petroleum Institute, First-Aid and Safety-Training Cuide for the Men and Women of the Petroleum Industry." This change was made to avoid Implication of duplicating or replacing other standards for flrst-ald training. If the proposed API schools for Instructors and awards for life savlx and rendering other meritorious first aid are eliminated, and If the guide and other visual aids are made available at nominal cost, It would seem that the API flrst-ald program would be more attractive to the various companies. Your subccamlttee believes that there is a need In the petroleum Industry for abbreviated training and retraining in the fundamentals of first aid. The scope of the proposed guide appears to be generally adequate and Includes the following essontlal points In flrst-ald training: API 07069 1. Artificial respiration. 2. Control of bleeding. 3. Treatment of shock. Care of open wounds and burns. 5. Care of dislocations and fractures. 6. Transportation of injured. Since we arc now in the atomic ago and in view of existing circum stances, this subcommittee believes that the proposed guide should include a brief presentation of appropriate measures to be taken by individuals before, during, and after atomic attack. In this connection, it is emphasized that individual defense efforts should be coordinated with that of the local civilian defense program. If and when the proposed Guide for First Aid and Safety Training has had official approval in principle by the API, your subcommittee will again review the guide in conference with the Committee on First Aid in an effort to finalize it. It is planned to circularize the guide to members of the Medical Advisory Committee for comment prior to its release. In connection with injuries resulting from specific hazards, this subcommittee believes that it is the responsibility of the respective medical and safety departments concerned, to determine tho nature of the first aid to bo rendered. ACTION The report was accepted. X REPORT OF SUBCOMMITTEE ON ECONOMIC POISONS - DR. T. J. KELLY. CHAIRMAN On behalf of tho subcommittee, Doctor Kelly moved the acceptance of tho report and adoption of two subccmmittoo actionem as follows: A quorum representation of the Subcommittee cn Economic Poisons has given consideration and genoral discussion to: 1. The nature and extont of tho problem of economic poisons as it rclatos to the petroleum Industry. 2. The committee's responsibility in meeting this problem with regard to tho scope of its activity. General discussion, including correspondence from Mr. Conley of tho American Modical Association, from Doctor Baird, Doctor Kehoe, Doctor Hoag, and Mr. Griffith, was centered about tho scope of the problem of tho oil Industry's responsibility in the matter, and sufficiency of information presently available on tho subject. In this discussion a line of demarcation was drawn between the medical responsibility with regard to physiologic offects and the non-medical responsibility with regard to Investigation of reBldueB. The consensus of opinion wub that there is insufficient knowlodge available at present on the physiologic effects of certain vohiclos and solvonts used in economic poisons. The committee members agreed that it would be the API 07070 -8- intcnt of this committee to investigate physiologic effects if so requested. A motion was made and carried, as follows: That a recommendation be made to the appropriate committee of the API to determine which petroleum products, and in what amounts, may exist as spray residue on food products. A second motion was alsc made and carriod, as follows: That a letter be addressed to Mr. Conley indicating the interest cf this committee in the problem of physiologic effects cf economic poisons, and that the cornaittce, if requested by the API, will attompt to investigate physiologic and hoalth aspects of the problem and develop information regarding any potential hazards to hoalth which may exist in the use of petroleum products as vehicles or solvonts in pesticides, insecticides, fungicides, and other economic poisons. ACTION The committee votod to accept the report. XI REPCRT OF SUBCOMMITTEE CN EYE HAZARDS - IB. F. F. BOYS. CHAIRMAN In the absence cf Doctor Boys, the chairman reported that the subcommittee was remaining inactive pending the formulation of the objectives of the Hygiene Panel of the Institute's Lubrication Committoe. It is under stood that the Hygiene Panel will call upon the subcommittee for advice on medical phases of its work. ACTION The conmittoc received the report and voted to continue the subcommittee. --' > XII REPORT OF EDITORIAL SUBCOMMITTEE - DR. MARSHALL CLINTON, CHAIRMAN Doctor Clinton reported on status of subcommittee work, as follows: The present status in regard to publication of the various Toxicological Reviews is as indicated on tho attached memorandum preparod by Mr. Stroop (See Appendix B for status of unpublished Toxicological Reviews). Comments on the reviews which have boon approvod for publication have gradually been collected and copies of the comments are now in the hand of the Editorial Subconsnittoe So far, tho subcommittee has not met wnri integrated these into tho various reviews, since the General Committoe, Division of Refining, and the Safety Committee of the Board of Directors havo ~ not yet decided on the matter of publishing these reviews. ACTION The progress report was received. API 07071 -9- CCESZCTED __ PAGE . XIII KETTERING LABORATORY PROGRAM OF EDUCATION IN INDUSTRIAL MEDICIKE Upon request Doctor Kehoe described in detail the program of graduate work in industrial medicine which was being established as a result of the favorable response to his letter of May 9 and memorandum of March 15 on this subject. Doctor Kehoe's explanation and the ensuing discussion brought about a better understanding of the matter and dissolved objections which had been voiced by some members. XIV HEW BUSINESS AND ADJOURNMENT In the absence of any new business, the chairman announced the convening of an executive session at 2:00 P.M., and the adjournment of the open meeting. THOSE PRESENT V. C. Baird L. C. Beard, Jr. R . C . Cole L. E. Curtis R. E. Eckardt R. W. Faulk T. M. Frank EXECUTIVE SESSION Kieffer Davis - Chairman _ B. B. Reeve - Vice Chairman Marshall Clinton - Secretary A. E. Hoag T. J. Kelly R. M. Landon E. P. Luongo - K. G. Mackenzie M. N. Newqulst W. H. Price F. J. Sanders R. M. Shepardson D. V. Stroop Chas. A. Swan E. Richmond Ware Mclver Woody A INSPECTION AND CERTIFICATION OF INDUSTRIAL MEDICAL ESTABLISHMENTS Those present discussed a memorandum dated August 1950 which vas addressed to the Fund Raising Committee, American Inundation of Occupational Health, relating to a program for inspection, consultation, and certification for individual industrial medical establishments which has been provided for many years by the American College of Surgeons. API 07072 - 10' It was the consensus of thoso present that the service which has boon provided, by the American College of Surgeons was important and its continuation Bhould have the support of industry. B BUDGET FOB FISCAL YEAR 1951-52 Budgetary rococmcndations were submitted as follows: 1. University of Cincinnati Carginogenic ity Fluorine Study* 2. Philip Drinker Minimum $85,000 0 5,000 Maximum $100,000 2,500 5,000 TOTAL $90-,000 $ 107,500 It was reported that oil-company contributions to the API Medical Research Fund for 1950-51 as of Novembor 1, 1950 totaled $9^,825. ACTION The committoc votod to adopt and to ask approval cf the budget recommendations for 1951-52, and to request authority for the Institute to solicit contributions from oil companies in the same amounts as those given in 1950. Note: In the absence of a meeting of tho Safety Conmittoe of the Board, the Program and Budgot Review Committee was asked to roviow and the Executive Committee of the Board was asked to approve a 1951-52 budget of estimated expenditures in the amount of $100,000, and to authorize the solicitation of $9^,825 cn the basis cf 1950 contributions. The necessary approvals and authorizations were grantod. 1 OPEN AND CLOSED MEETINGS OF MEDICAL ADVISORY COMMITTEE AND ITS SUBCOMMITTEES t .......................................... ~~ ; Members expressed opinions that the committee work was being delayed and in some csbos Jeopardized by the number cf guests in attendance, particularly I when guests arc unknown and unidentified. It was generally agreed that invited guests should be privileged to attend but in each case all members should be notiflod in advance of such attendance, if possible. j * Contingent upon continuation of cooperative work by industrial group, end I that API share of cost shall not exceed 25 per cent of tho total cost I during the year. API 07073 CTICN - 11- / The committee voted as a matter of policy that future meetings of the Medical Advisory Committee end its subcommittees should be "closed" except for the first of the two sessions of the Medical Advisory Committee;. I) PUBLICATION OF RESEARCH DATA Mombers discussed at length the problems Incidental to the publication of research data resulting from Project M2 at Kettering Laboratory. Reference was made to the second paragraph on page 28 of the current interim report which stated: "However, it was apparent to all who considered this problem critically that the results obtained in the determination of the physical properties of materials or with their effect on experimental animals could not be translated readily or directly into probable human reactions. Likewise, oven if a correlation of physical properties and the response of man should be demonstrated under a given set of circumstances, it would be difficult to relate isolated observations to the various levels of possible employed exposure associated with the several refining processes." ACTION The committee voiced its sympathetic understanding of the need for prompt publication of research data resulting from the work at Kettering Laboratory, but votod that the first article cf the scries should be a general introductory paper prepared by Doctor Kehoe to prepare tho way fdf the more specific data which would be published subsequently. ACTION E * THIRTEENTH MEETING . The committee voted to hold its thirteenth meeting at the Hotel Haddon Hall, Atlantic City, Now Jorsoy, on Friday and Saturday, April 20-21, 1951> immediately preceding the meeting of tho American Association of Industrial Physicians and Surgoons. F ADJOURNMENT There being no further business to be considered, the meeting was adjourned. Approved: Klrffcr Davis, M.D. Chairman Marshall Clinton. M.D. Secretary 1-5-51 API 07074 For Information Only - Not For Public atlcn APPENDIX A To Minutes of 12th Meeting of Medical Advisory Consaittee REPORT TO THE API MEDICAL ADVISORY COMMITTEE BY THE SUBCOMMITTEE ON FLUORIDES Dr. A. E. Hoag - Chairman November 10, 1950 Doctor Hoag called attention to Doctor E.' J. Largent's publication entitlod "Effocts of Fluorides on Men and Animals." Reference was made to the visit by Doctors Davis and Hoag to Kettering. Doctor Eehoe said that several othor companies had Joined the cooperative sponsoring group; that he was of the opinion said sponsoring group would continue its support. A report has been issued by Kettering on the work to dato but had not yot reached API represen tatives. The main objective of the work at Kettering is to determine the mechanism of the metabolism of the fluoride ion in men and determine what harmful effects, if any, obtain. Studios ore also in progress on inhalation of HF to more adequately define toxic concentrations. Attention was called by Doctor Kchoo Xb the availability through the sponsoring companies of their independently financed work on effects of HF on vegetation. Doctor Hoag Bolicitod the opinion of various porsons re continuod support. The ccnsonsus was the work should be continued and the discuBBion culminated in a motion by Doctor Roeve that it be recommended to tho API Medical Advisory Consulttoo to budget $2,500 for continuation for another year, but that expenditure thoreof be contingent on the continuing support of the majority of the other sponsoring groups. API 07075 For Information Only - Not For Publication APPENDIX B To Minutes of 12th Mooting of Medical Advisory Committee STATUS OF UNPUBLISHED TOXICOLOGICAL REVIEWS November 1950 Toxicological Reviews approved by Medical Advisory Committee for publication, and distributed to General CoTMittee, Division of Refining. May 31 1930: Acetic A c i d .............................................. Acotone ......................................... Bcta-Naphthol ............................................ Butyl Acetate ................. ........................... Carbon Monoxide .......................................... Cyclohexane .............................................. Hydrogen Fluoride ........................................ Mothylcyclohexane ........................................ Phosphoric Acids ......................................... June June June June Juno Juno June June June 1950 1950 1950 1950 1950 1950 1950 1950 1950 Revised Drafts: "Anmonium Molybdato ....................................... "Ammonium Nitrate ........ ............................... "Amyl Acetate ............................................. Arsine .................................................... Butadlonc .............................. .................. D.D.T..................................................... "Ditcrtiary Butyl Para Cresol ............................. "Hydroqulnone ............................................. "Maleic Anhydride .... ..................................... "Mcsitylono ............................... ............. Naphthalone ................... ................^ ......... Nickel Carbonyl .......................................... Propyl Alcohols ........ .................................. "Silica ................................................... Thlophenyl and the Aromatic Morcaptans ................... "U.O.P. # 5 ................................................ Juno 19^9 June 19**9 February 19^9 May 1950 April 1950 April 1950 August 19^7 March 1950 May I9U8 March I9U9 March 1950 February 1950 April 1950 August 19^7 August 19^7 Juno 19**9 Tentative Drafts: Copper Naphthenate ................. ...................... Methyl Alcohol ......................................... . "Phonylalphanaphthylaminc & Phonylbotanaphthylamlno ....... Pyridine ....................................... .......... Solvent Naphtha .......................................... TTlchlorothyleno ...................................... . Triethanolamine ..................................... ....... February 1950 May 1950 July 19U7 February 1950 February 1950 May 1950 February 1950 Approved for publication April 2k, 1950 by the Medical Advisory Committee. API 07076