Document a1RkY0Y4aXr7Yqe1p0LQEz8Za

April C, 1957 Nr, James o, Lofstrom it&nd&rcl oil Company 30 Rockefeller Plaza Itow York SO, New York Dear Nr, lofstromi I have bean asked to forward to you toxlei$y-data^n our fluids, Pydraul V-9, Pydraul 150, Pydraul 600, and Pydraul AffK Prdraui p-9 Thar* has bean considerable toxicity research on Pydraul r-9, Attached la a diaouaalon and Interpretation of the taxloity atudlea. The re suite are also summarized In a briefer fashion an page 18 of the attached Pydraul P-9 Technical Bulletin. Pydraul iso lht toxicity report on Pydraul 150 indicates that It le practically lnnoeueui when fed orally to rata alnea the animal* survived single doeea of 2tt,5 grams per kilogram with lose of appetite and aevert diarrhea aa the only toxic effects. The fluid apparently la not absorbed through the unbroken akin of rmbblta since this epecles survived doeea up to 9,5 gratae per kilogram of body weight. In rabbit akin and eye Irritation atudles, Pydraul 150 was no more Irritating than a 100 soap solution tested similarly. As indicated with Pydraul P-9 above, however, Pydraul 150 trill eauoo severe pain If there la aooldental splashing In the eyes of humans, Bats survived a 6-hour exposure to an atmosphere saturated with Pydraul 150 vapors. Pydraul 60Q The oral lethal dose for rats In approximately 30.5 grama per >< Ho urs*. When applied undiluted to the unbroken skin of rabbits tlu lethal dose was from 3.9 to 5.2 grama per kilogram. Animal skin and eye irritation atudlea Indicated that Pydraul oOO it not a akin Irritant. Me know from experience with humane that accidental splashing in the eyea does oauae severe pain but no permanent Injury. Rats survived a 6-hour exposure to an atmosphere saturated with the vapors of Pydraul 600. MONS 091001 If> Janes 0. temrcm--Pag 2--April 8, 1957 The oral lethal dooe In rets it approximately to t,rohm par idlo^rsn i>ntf th> aJ.niifua lethal dooo by u'iJ.n absorption fin rab* l i .0 to fs.O grane per kllograw. Rabbit akin and eye Irritation stodlss JjKUaatu that Rydraul AO la not a serious .'.rrltsnt, Aooldeatai sontaat nlt;h the eyes in the case of hunana will result In Irritation but no permanent damage, .lets survived a G-hour exposure to an atmosphere saturated with vapors of Pydraul AC. if t 3an be of any further ur. istanae, please lot ns know, Slnoerely youro. xrvtfli Enoloeurea oe If. M. 0, PV-swer Elmer f, v:hcler Assistant Dlrwtor Medloal Department