Document a13b26enzvKrx4JjMR7gRQ2eb
c
0 P Y
DEPARTMENT OF HEALTH. EDUCATION. AND WELFARE
PUBLIC HEALTH SERVICE NATIONAL INSTITUTES OF HEALTH
BETHESDA. MARYLAND 20014
May 23, 1974
NATIONAL CANCER INSTITUTE
Dr. Kenneth D. Johnson Manufacturing Chemists Association Suite 411 1825 Connecticut Avenue, N.W. Washington, D.C. 20009
Dear Dr. Johnson:
Attached is a list of chemicals which are being assayed for carcinogenicity
by the Bioassay Operations Segment of the National Cancer Institute. Please
review this list and if you wish additional details on the test procedures,
please provide us with a request for that information.
Thank you for your interest.
Sincerely yours
Enclosure
Chief, Carcinogen Bioassay and Program Resources Branch
Carcinogenesis, DCCP, NCI Landow Building, Room C325
VVC 000006224-
CHEMICALS BEING TESTED FOR CARCINOGENICITY BY THE BIOASSAY OPERATIONS SEGMENT CARCINOGENESIS PROGRAM, DCCP, NCI
APRIL 3, 197A
Chemicals tested In this program are selected on the basis of human exposure, production levels and chemical structure. They, should not be considered as suspected carcinogens by virtue'of being in the testing program.
VVC 000006225
CHEMICALS BEING TESTED FOR CARCINOGENICITY BY CARCINOGENESIS PROGRAM, DCCP, NCI
NCI # CHEMICAL NAME
C01967 C021 08 C04035_ C018B7 C03770 C03974 CO 54 4 7 C025U0 CO 27 66 CO 14 45 C0 3349 C02755 CO 4137 CO 1536 COU682
C0U002 C02095 CO 1514
CO 1 4 56 CO 00 4 4 C05458 C0G055 C047 5 1 C034 19 CO 24 3 7 C02960 CO 54 69
CO 37 36 " C02039 C02255 CO 22 66 C01821 CO 1718 C01707 C02460 *
ACEN APHTMENB, 5-NITRO-
ACETAMIDE ACETAMIDE, N,N-DIALLYL-2-CHLORO-
ACETANILIDE, 3-AMINO-4-ETHOXY-
ACETANILIDE, 4'-(CHLORCACETYL)-
ACETIC ACID, (ETHYLENEDINITRILO)TETRA, TRISODIUM ACETIC ACID, MERCA PTO-, MONOSODIUM SALT
ACETIC ACID, NICKEL (2 + ) SALT ACETIC ACID, NITRILOTFI -
ACETIC ACID, NITRILQTRI-,TRISODIUM SALT
ACETOHYDROXAMIC ACID, N-FLOUREN-2-YL-N-HYDROXY
P-ACETOPHENETIDIDE
ACRIDINE, 3,6-DIAKINO-, MONOHYDROCHLORIDE) -
AC90NYCINE
ACTINOMYCIN D
1-ADAMANTANA MINE ........
............
....... ........ .
ADIPAMIDE
ADRIAMYCIN
AFLATOXIN B1
AIDRIN N-ALLYHYDRAZINE
AMID EM
"...................... .......................
4-AttINOBlPHEHYL, 3,2 *-DIHETHYL-
4-AMINOBIPHENYL, 4'-FLU0U0-
AMINOCHLORODIPHENYL ETHER AMMONIUM , (2- CM LOR 0 ETHYL) TRIHE^H YL- , CHLORIDE
N-AMYLHYDRAZINE
ANILINE
...........
ANILINE, P-CHLOROAtJILINE, 2,4- DIM ETHOXY-, HYDROCHLORIDE..................
ANILINE, 3,4-DIMETIIOXY-, HYDROCHLORIDE
ANILINE, N ,N - DIMKTIIY L-F-NITROSO-
ANILINE, 4,4 -SULFONYI.DI-
ANILINE, 4,4 -THIODI-
'
ANILINE,2,4,6-TRICHLORO-
SALT
<
<o o o o o o
O'
ro N O'
April 3, 197A
CAS #
SEGME
60-35-5 93-71-0
140-49-8 150-38-9 367-51-1 373-02-4 139-13-9 5064-31-3
53-95-2 62-44-2 952-23-8 7008-42-6 50-76-0 768-94-5 628-94-4
1162-65-8 309-00-2
133-90-4 13394-86-0
999-81-5
142-04-1 106-47-8
130-89-6 00-08-0
139-65-1
BOS BOS BOS
BOS BOS BOS BOS BOS BOS BOS . BOS BOS BOS BOS BOS BOS nos BOS BOS BOS BOS BOS
BOS BOS
BOS BOS BOS
BOS BOS BOS BOS BOS BOS BOS EOS
NCI* # CHEMICAL NAME
CO 2 2 99 ANILINE, 2,4,5-TRIMETHYL-
.CQ3587._ a?JT ms, 2,4,5*TRIMETHYL-# HYDROCHLORIDE
C02208 ANILINE, 2,4,6-TRIMETHYL, HYDROCHLORIDE
C02993 P-AN I SI DINE, 2-METHYL-
CO 1999 ANISOLE, 2, 4-DIAMIN0-, SULPHATE
C03032 ANISOLE, 2,3,5,6-TETRACHLORO-4-NITRO-
C01730 ANTHRANILIC ACID
C03510 ANTHRANILIC ACID, CINNAMYL ESTER
CO 1945 A NTH R A NILIC ACID, 4-NITFO-
C019 7 6 ANTHR AQHINONE, 2-AMINO
CO 3634 ANTHRAQUINONE, 1,4-DI-P-TOLUIDINO-
CO 3 6 4 5 ANTHRAQUINONE, 1,4-DIMETHYLAMINO-
CO 1923 ANTURAQUINONE, 2-METHYL-1-NITRO- ........__
C06042 ANTI-SEBORRHEIC SHAMPOO...............
C02697 A PC
C03383 APHOXIDE
C04728 A RABINOSYLCYTOSINE
C02120 L-ARGININE GLUTAMATE
C0U364 ARSENIC
__ ____________ ,,____
C04104 AURAMINE
CO 6 393 AVADEX
CO 1569 5-AZACYTIDINE
C06371 AZIRIDINE, 2-methyl-
CO 292 6 azobenzene
COOU31 B AYLUSCIDE
C05470 BEN7.ALK0NIUM CHLORIDE
C03576 7H-BENZ (DE) ANTHRACEN-7-CNE
C02426 BENZENE, 1-CHLORO-2,4-DINITRO
C02404 BENZENE, 1-CHL0R0-4-NITR0C004 19 BENZENE, PENTACHLORONITRO-
1
com 15 BENZHYDROL, 4,4'-BIS (DIMETHYLAMINO)-
C03361 BENZIDINE
CO 1912 BENZIMIDAZOLE, 6-NITRO-
<
C05481 BENZOIC ACID, P-AHINO
CO5492 BENZOIC ACID, SODIUM SALT
/
/
7
/
/
CAS #
segment
137-17-7 BOS
BOS
BOS
102-50-1
BOS
BOS
2438-80-2 BOS
118-92-3 BOS
87-29-6 BOS
BOS
117-79-3 BOS
120-80-3 BOS
128-92-7 BOS
129-15-7 BOS
xx-xx-x BOS
8003-03-0 . BOS
545-55-1
BOS
147-94-4 BOS
4320-30-3 BOS
7440-30-2 BOS
492-00-8 do:
2303-16-4 BOS
320-67-2 BOS
75-55-8 BOS
103-33-3 BOS
1420-04-8 BOS
8001-54-5 BOS
82-05-3 BOS
97-00-7 BOS
100-00-5 BOS
82-60-8 BOS
119-58-4 BOS
92-87-5 . BOS
94-52-0 BOS
150-13-0 BOS
532-32-1 BOS
NCI # CHEMICAL NAME
CO 550 5 BENZOPHENONE
C02006 B ENZ 0 PEIEMOME, 4 ,4 '-BIS (DIMETHYLAMINO)-'
''
CO 0282 BENZO (A) PYRENE
C03R50 P-BENZOQUINONE, DIOXIME....................................................
C03521 IH-BENZOTRIAZOLE
Z05516 benzoylhydrazine
................
...........
:05533 BENZYLHYDRAZINE DIHYDROCLORIDE
:0171 "BIGUANIDE, 1-PHENETHYL- `
.............. .............
;02 664 BIPHENYL, CHLORO
;0 1525 BLEOMYCIN
:01592 1,4-BUTANEDIOL, DIMETHANESULFONATE
:0 1434 1-BUTANOL, 4-(BUTYLNITROSAMINO)~
:05549 N-BUTYLHYDRAZINE HYDROCLORIDE
:0 2131 N-BUTYLUREA
.......... .............
:06188 BUTYRIC ACID, BENZYL ESTER
:0 3405 BUTYRIC ACID, 4-(P-(BIS (2-CHLOROETHYL) AMINO) PHENYL) -
:0 2 52 8 CADMIUM
:02573 CADMIUM CHLORIDE'
:02551 CADMIUM OXIDE
0271 1 CADMIUM SULPHIDE
................ ... ........................................ '.................... .
02733 CAFFEINE
'00691 CALCIUM C HROMATE(DUST)
00077 CAPTAN
0 4 808 CARBANALIDE,4,41-DIACETYL-BIS-(AMIDINOHYDRAZONE) ,DIMETHANE SULFONATE
05550 CARBAMIC ACID,&BUTYL ESTER
02835 CARBAMIC ACID, DIMETHYLDITHIO-,"SODIUM SALT ................ .....................
00602 CARBAMIC ACID, ETHYL ESTER
04024 CARBANILIC ACID, M-CHLORO-, 4-CHLOBO-2-BUTYNYL ESTER
01898 CAR3AZOLE, 3-AMINO-9-ETHYL-
j
03043 CARBAZOLE, 3-AMINO-9-ETHYL, HYDROCHLORIDE
04591 CARBON DISULFIDE
03452 CARBON TETRACHLORIDE
06417 CARBONIC ACID, CYCLIC ETHYLENE ESTER
<
05527 CARCINOGENIC DEOXYRIBONUCLEIC ACID
04773 CARMUSTINE
...................................... ....
0
o o o
o
O' IrSo>
CD
.
CAS #
119-61-9 .90-94-8
50-32-8 105-11-3
95-14-7 613-94-5 1073-62-7 114-06-3 1336-36-3 11056-06-7
55-98-1 3817-11-6 7400-27-3
103-37-7 305-03-3 7 440-43-9 10108-64-2 1306-19-0 1306-23-6
58-08-2
133-06-2
592-35-8 128-04-1
51-79-6 101-27-9 132-32-1
75-15-0 56-23-5 96-49-1
154-93-8
SEGHBBT
BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS
NCI # CHEMICAL NAME
CAS #
C05572 CARRAGEENAN
C00099 ` CHLOHDANE COO 40 8 CHLORODENZILATE
C02686 CHLOROFORM CO 38 61 5DETA -C IIOLAN-24-OIC ACID, 3-ALPHA-HYDROXY-
C01558 CHOLESTEROL, (P- (BIS (2-CHLOROETHYL) AMINO) C03203 CHROMIC ACID(H2 CR 04), LEAD_ (2 + )_ SALT _(1.S
C04273 ' CHROMIUM
................... ..
C06906 CHROMIUM INDUSTRIAL RESIDUE
CO 073 7 CHROMIUM OXIDE (CR 2 03)
C06917 CHROMOMETHYL ETHER
C00680 CHRYSOTILE
C00679 CIGARETTE SMOKE,TOBACCO __
_
CO 692 9 ' CIGARETTE TOBACCO TAR
CO559 4 CITRIC ACID CO 560 7 CITRIC ACID, SODIUM SALT
C07056 COAL DUST
C07067 COAL TAR CO70 7 0 COAL TAR, ACIDIC FRACTION
____ _____
C07089 COAL TAR, BASIC FRACTION
C07090 COAL TAR, NEUTRAL PORTION
C04411 CODALTOCENE
C07103 COUMARIN
C03598 P-CRESOL, 2,6-DI-TERT-BUTYL- ..................................
C01467 CYCASIN
_ ___
C056 18 CYCLAMATE, CALCIUM SALT...........
C02277 CYCLAMATE,SODIUM SALT
C04900 CYCLOPHOSPHAMIDE.......................................... ...
CO0102 DACONIL
)
C06053 DANDRUFF CONTROL C01683 DARAPRIM
__
C04693 " DAUNOMYCIN C04933 0,P'-DDD CQ0475 PrP*-DDD C00555- DDE ......
i
........ .................................
,< ,
oo o
ro * r>soi
....... ........... ..
PHENYL) ACETATE )
.............................
__ 9000-07-1 7 ...... rv' 57-74-9
510-15-6 67-66-3
434-13-9 * 3546-10-9
7758-97-6 7 440-47-3
............. '
"
* 1308-38-9
12001-29-5
............. ...................
............ ............. ..
77-92-9 994-36-5
......"
8007-45-2 j
........... ....... ` .... .. ...........
91-64-5
...............................
.Wi
128-37-0
__ _ 14901-08-7
~ ............ .........................
139-06-0
139-05-9
,", ,
..........
..................50-10-0
1897-45-6.
XX-XX-X
50-14-0
.........................
20830-81 -3
5.3-1.9-01
72-54-8
34,24-82-5
SEGMENT
BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS
BOS BOS BOS BOS BOS DOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS SQS
noon n n n n o n n n n o n o O o O O o n o n n n o o O O O n n n n
Oo Xs X?
K> N>
O x= _k
O -C=
o
--ok
o
.c to
o ON
o
o
o to
o
o i_n
o
o --k
o
c u>
o ro
xs
o .c
Ul
o Ul o
o xr
CD
o ru
o
o Ul xs
o
UJ ro
o -4
o c X
_oi
CTi
--o*
ON
o
cn cn
o U) ON
o Ui
o
UJ UN
o Lu ON
o Ui ON
o Ui
UN
o Ul
ON
o UI ON
o
m ON
o
Ui CO
o UN
o -4
..
O - NO a Ui ro --k 4 NO to NO .e a c a to Ui a ON vo ON UN ON CO
o ON UI ON UI SS UJ ON 3 to
ON *4 3 CO cn a so
sO -cr -4 CD O' NO Ul CD o o to ui
o UJ o
3 -J ON UI to
O NO -k UN
I
*
ns *-t * * %
3 to
*3 -
*o
G--
H1 1 i
ao a o
OH M H
X3 3 3
xa W a
oH
Ha
H a
H
*o o o O
ax X X
tao
Xa
X a
cXs
x a 3
a a 4
az C4
za N
ao O
4
ra
G a
X
a
z a
eag oz
a
Z
o z
a o e-*
aa
g
w 3 a 4 a o
--4 a
ns z a o
X M
ns z a a
-- t t-3 a
i o ES o
awXa
MaaM
a H s* z
X z z *
o X a T3
aazG
o i aO
X 3 t-9
X t zO
aH i
za C4
O C*
G
Mz H
z 3 50
XMo
o O V)
aao
o
(
r*
cs M a a o z M
Z
oO
Ma
1O
GX
wO
1a
no
X ns
na az o 3
ns s*
a
z
ao
i-3 az
ga
a
a z
ao
Xo
aX
za
M n
ag
a
W
Ggo
a
n
a
n
a
n
X X"
o Oa
aao
o o 50
g
az a
*--*
a
X X
O 3
a a
a ^2
a ** o
a
a
3a
a
M
az
za
a
X
SB*
za
ia
az
a
50
o 01 o
G a a G a X a a >--*
z
G
a
>
n aa s* a a
oa a 50
aa Ga
a
X to a
5* u>
a3
z
1
Ga
aa
50
o
zi z
3
Ons
a to
aO
50 G
OX
aa o 1' 1a
3 O
to
o a 03 a o 3 o 3
Z
z a a o a
o a <33 "O o rg
O o G
a n a a
o
a
o a CO a 53 N X
aa
z
a
3 X
Gto O n
3
a
O to
a
G
to
G a a tn z CS) X a 3 3 a
z
M
Z
1
to1 n
3
a o a o W a
GGaOG
aaaaa
3 CD 3 CO 3
aaa aa
53 z z z z
ts C4 X ts) tS)
oO Oo
s 1 I 1 1
a
a i
a
i
a i
a i
a
o
a
aa
o
a
aa
XoooO
a czwo
Xa z
X
a z
X
a z
X
a *z
N> ro % to
OJ UI to -4
1
**o
U>
1
G
a
a CD n
to a
1 a
on
3a
G o -4 G
aa 1 a
333 3
Wz
az
\ G
az
CO CS) a C4
oo3
a1
3
a z
CS)
ao
o a
n
--
o a r>
X --
an
o
z
a
z 33 o aO
x to z
Ui 3 a
CO >
z C4
aO
ia
O M
_k
17
G a 3
za
ts)
s*
3
O w
a aG z a
G a 3* to X a a
z a a
o a
Xa a a o
Gz a ao >a
io o a3 oa X X
a
3
a oo
G
3 0O1 a z. a
!1
M
a1
G
3 o to < O
1
i
3 B X 3 a to G
W 88
1
>
w3
a
aO
t>o
%
cr>
o
a o
an*
.a
0 a no
a
1 t* l
oo
to 0
o4
0Z900000 OAA
1n
SMS
of a o
o
o wZ M o t> r* eg 3 a
33
z
UJ
i o 3 3 3
oo
sO
3
A Ul Ui m 3 3
sO m o NO mX {= UJ 3 -4 Xs to 3 NJ to 3 _k 3 3
3 *4 to 3 to _
to ro o
Ul C? 3 Ul 3 to NO JO to
_k to
s* a
O O ? Ul 3 o --* -4 *4 3 a e 3 3 3 3 _k a 3 3 -4 to 3 C? xs 3 a C-
1 1 1 1I t1 11 it11I 1 1 i 1 1 1 1 11 t1
1 4*
sO Ul 3 _* -4 Ul to -4 NO *4 Ul _k ~4 XT ro 3 Ul to o 3 to _k 3 Ul IS 3 o
ON --* to 3 Ul X --k UJ to Ul 3 to wk 3 to o 3 _k 4 3 to 3 NO to 3 to 3
_
I
1
11I1
itt|t111|*1
1 1 1 1 1 1 1 1 1 ~4
1
O Ul Ul Ul NO
o 3 to Ul o Ui 4 ui O 3 3
to 3 NO o
Ul to O 3 X:
Ul
33 33 3 3 3 3 3 3 3 3333 33 3 3 333 3 3 3 3 3 333 3 3 3 3 3
OO (A O)
O 3
O a
o a
O V)
O a
O a
O a
O a
O a
O a
O a
O a
o a
O a
OO aa
O a
O a
O a
O a
o a
o a
o a
O a
O a
O a
o a
o a
o a
O a
O a
O a
o a
a
3 a
3 M
foci CHEMICAL NAME
CAS
SEGMENT
C05050 DiriET HY LAMINE, N-NITROSO-
C036Q9 P-PIOXANE
COO 395 DIOX A TII ION
C02700 DIPENTYLAMINE, N-NITROSO-
CO 2080 DIFIIEN Y1A MI NE , N-NITROSO-
C02244 DIPHENYLAMINE, 4-NITROSO-
C04171 2-DIPHENYLIMINE, 4-AMINO-
CO 5061 - DlPROPYLAMINE, N-NITEOS0-
C02959 DISULFIDE, BIS(DIETHYLTHIOCARBAMOYL)-
C03009 2,5-DITH10BIUREA
C07147 DODECANE
CO 5674 DODECYLAMINE, N,N-DIMETHYL-, ACETATE
C01605 EMETINE
CO 0157 ENDRIN
CO1570 ESTRADIOL MUSTARD
CO 0522 ETHANE, 1,2-DIBPOMO-
C0U535 ETHANE, 1,1-DICHLORO-
CO 051 1 ETHANE, 1,2-DICHLORO-
CO 20 6 8 ETHANE, 1 ,1-DICHLORO-2,2-BIS (P-ETHYLPHENYL) -
CO 4604 ETHANE, HEXACHLORO-
CO 3 554 ETHANE, 1, 1,2,2,-TETFACHLORO-
CO 4626 ETHANE, 1,1,1-THICK LORO-
C0U579 ETHANE, 1 ,1,2-TRICHLORO-
CO 04 64 ETHANE, 1,1; 1-TP.I CH LORO-2,2-BIS(P-CHLOROPHENYL) -
C05685 ETHANOL, 2-HYDRA 2IN0-
C06406 ETHER, BIS(2-CHLOROETHYL) -
CO 3996 ETHREL
CO 56 96 ETHYL HYDRAZINE HYDROCHLORIDE
CO 458 0 ETHYLENE, TETRACHLORO-
CO 454 6 ETHYLENE, TRICHLORO-
'
C03281 ETHYLEMEDIAMINE, N-1-NAPHTHYL-, DIHYDROCHLORIDE
CO 57 09 ETHYLUREA
CO 42 39 FERROCENE
<
C00168 GARDONA
<
CO 4353 GOLD
o
62-75-9 BOS
... 123-91-1 BOS
78-34-2 BOS
13256-06-9
BOS
86-30-6 BOS
. 156-10-5 BOS
BOS
621-64-7
BOS
97-77-8 BOS
BOS
112-40-3 BOS
1920-05-4 BOS
483-18-1
BOS
72-20-8 DOS
BOS
106-93-4 BOS
75-34-3
BOS
107-06-2 BOS
72-56-0 BOS
67-72-1
nos
79-34-5 BOS
71-55-6 BOS
79-00-5 BOS
50-29-3 BOS
109-84-2 BOS
111-44-4 BOS
BOS
BOS
127-18-4 BOS
79-01-6 BOS
1465-25-4 BOS
625-52-5 BOS
102-54-5 BOS
961-11-5 BOS
7440-57-5 BOS
o o ................. ................. ................ ............................. .... o ON' 1W-*
MCI * CHEMICAL NAME
C05710 GRIS EOF U LVIN
'CO 48 1 9 GUANAZOLE
CO 14 2 3 GUANIDINE, 1-METHYL-3-NITR0-1-NITR0S0-
CO 00 66 GUSATHION
CO 60 75 HAIR SPRAY
C00180 HEPTACHLOR
C02653 HEXACHLOROPHENE
' C05 094 ' HEXAMETIIYLENEIMINE, N-NITROSO-
CO 214 2 HEXANAMIDE
CO 5721 1,3-HEXANEDIOL, 2-ETHYL-
C03054 HYDANTOIN, 1,3-DICHLORO-5,5-DIMETHYL-
CO 473 9 H YDF A ZIN E , 1 - ACET Y L-2 -PICOLINO YL-
CO 57 3 2 HYDRAZINE,1,1-DIMETHYL-
CO 574 3 HYDRAZINE, 1,2-DIMETHYL-, DIHYDROCHLORIDE "....... . ......
C 018 54 HYDRAZINE, 1,1-DIPHENYL-
CO 5754 HYDRAZINE, PHENETHYL-, SULFATE (1:1)
C03429 IIYDR AZINE, SULFATE
CO6302 BIS(2-HYDROXYETHYL) DITHIOCARBAMIC ACID, POTASSIUM SALT
C03258 HYDROXYLAMINE, N-NITPOSO-N-PHENYL-, AMMONIUM SALT
C05776 deta-hydroxypropyl-propylnitrosamine
CO 483 1 HYDROXYUREA
C 0 4 7 1 7 IMIDAZOLE CARBOXAMIDE, DIMETHYLTRIAZENO
CO4091 IMIDAZ0LE-1-ETHANOL, 2-(P-FLUOROPHENYL)-5-NITRO-
C01616 IMIDAZOLE MUSTARD
CO 3 37 2 2-IMIDAZOLIDINETHIONE
' CO 347 4 ' IMURAN
....................... .......... ......................*......... .
CO 426 2 IRON
C06268 ISOBUTYRIC ACID, PHENETHYL ESTER
C02175 ISOCYANIC ACID, 3, 3 -DIMET HOX Y-f4,4 -BIPHENY LENE ESTER
CO 57 8 7 ISONICOTINAMIDE
C05798 ISOHICOTINIC ACID
C05801 ISONICOTINIC ACID HYDRAZIDB..........
CO 1638 ISOPHOSPHAMIDE
C00U86 .KELTHANE
<
C00191 KEPONE
n
CAS ft
SEGMENT
126-07-8 503-88-8 * 70-25-7
86-50-0 xxx-xx-x
76-44-8 70-30-4 932-83-2 628-02-4 94-96-2 118-52-5 17433-31-7 57-14-7 306-37-6 530-50-7 156-51-4 10034-93-2 23746-34-1 135-20-6
127-07-1 4342-03-4 4548-15-6
96-45-7 446-86-6 7439-89-6 103-48-0
9 1-93-0
55-22-1 54-85-3 3778-73-2 115-32-2 143-50-0
BOS
BOS BOS BOS
BOS BOS
BOS BOS BOS DOS BOS BOS BOS BOS . BOS BOS BOS BOS BOS BOS BOS BOS DOS BOS DOS
BOS BOS
BOS BOS BOS BOS BOS BOS BOS BOS
NCI CHEMICAL NAME
CO 1470 CO 4 34 2 CO 3407 C 028 9 1 C03532 CO 4660 C03543 CO 0 204 CO 5378 CO 0215 CO 2517 CO4408 CO 3214 C04853 CO 4 94 4 CO 4 886 CO 4375 CO 4 513 CO 414 8 CO 3849 C046 37 CO 0 53 3 CO 4 568 CO 3190 C0467 1 CO 04 97 CO 716 9 C07170 C07181 C07192 CO230O CO 44 99 CO 3010 CQ5118 ,
y
LASIOCARPINE LEAD
LEAD SUPACETATB LEDATE LEVOMINE BLUE BN-M LEVOMINE RED KB-S LEVOMIN E RED PT-S LINDANE LUCANTHONE MALATHION MANGANESE
MANGANESE ACETYLACETGNATE MANGANESE OXIDE (MN C 2) MELPHALAN O-NELPHALAN 6-MERCAPTOPORINE MERCURY MERCURY OXIDE METHANE, BROMO-
MKTIi ANESULFONIC ACID, IODO-, METHANE, TRICHLOROFLUOROMETHANE, TRICHLORONITROMETHANE, TRIIODO-
SODIUM
SALT
METHANSULFON-M-ANISIDE,4'-(9-ACRIDINYLAMINO)-,MONOHYDROCHLORIDE
METHOTREXATE
METHOXYCHLOR
2-METHYLBENZ(A)ANTHRACENE
5-METHYLBENZ (A) ANTHRACENE1
7-METHYLBENZ (A) ANTHRACENE ,
8-METHYLBENZ (A) ANTHRACENE
4,4*-METHYLENE-BIS-(2-CHLOROANILIHE) HYDROCHLORIDE
METHYL MERCURY CHLORIDE ,, 1 ...
METHYL ORANGE ,B.
METHYLPRO.PYLNITROSAMINE
5
rethylthioinosine
o oo
.............. ... ......... -- oo ------O' N
v>
'
CAS #
SEGMENT
303-34-4 BOS
7439-92-1 BOS 1335-32-6 BOS 19010-66-3 BOS
119-92-6 BOS * 136-28-7 BOS
103-21-9 BOS
58-89-9 BOS 479-50-5 BOS 121-75-5 BOS 7439-96-5 BOS
BOS 1313-13-9 BOS
148-62-3 BOS BOS
50-44-2 BOS 7439-97-6, BOS
BOS 7U-03-9 BOS 126-31-8, BOS 75-69-4 BOS 76-06-2 BOS 75-47-8 BOS
BOS 59-05-2 BOS 72-43-5 BOS
BOS 2319-96-2 BOS
BOS 2381-31-9 BOS
BOS 115-09-3 BOS 54,7-58-0 BOS
BOS 342-69-8 BOS
NCI CHEMICAL NAME
C01 990 MICHLEP'S HYDRIDE
C06428 MIREX
CO 4 706 MITOMYCIN C
CO 4 3 31 MOLYBDENUM
CO 216 4 MORPHOLINE, 4-NITROSO
C05834 MYRISTIC ACID, ISOPROPYL ESTER
C02915 2-NAP H THY LA MINE, N-PHENYL-
C03021 1,5-NAPHTHALENEDIAMINE
CO 19 56 NAPHTHALENE,1-NITRQ
C00351 NICKEL
..................
CO 444 4 NICKEL COPPER ALLOY
C04422 NICKEL IRON ALLOY
C04433 NICKEL IRON MOLYBDENUM ALLOY
CO 4466 NICKEL ISODECYLOPTHOPHOSPHATE
CO 44 55 NICKEL TITANATE
CO 584 5 NICOTINAMIDE
C05G56 NICOTINE, HYDROCLORIDE
C05867 NICOTINIC ACID
C040B0 NICOTINIC ACID, 2 - (3 -CHLORO-O-TOLUIDI NO) -
CO 4 0 4 6 NITRALIN
CO 042 0 NITROFEN
C05141 NITROSODIHYDROURACIL
C05152 NITROSOETHYLURETHAN
CO 516 3 NITROSOGUVACOLINE
CO 5174 NITROSOMETHYL DODECYCLAMINE
C05185 " NITRO SOME TflYLPH ENID ATE
.....................................
CO 519 6 NITROSOPHENMETRAZINE
C04740 1-NITROSOUREA,1-(2-CHLOROETHYL)3-CYCLOHEXYL
C020B4 NITROUS ACID, SODIUM SALT
|
C03952 NORPHENAZONE
CO 5878 ORNITHINE, N5-CARBAMOYL-, L-
C06439 OXAHIDE, DITHIO-
..... ..........
C03350 1, 2 OXATHIOLANE, 2,2-DIOXIDE
C03394 .2-OXETA NONE
<
C04126 2-0XETAN0NE, 3,3-DIMETHYL-
<
*. .....................
.
CAS ft
SEGMENT
101-61-1 2305-85-5
50-07-7 7439-98-7
59-89-2 110-27-0 135-88-6 2243-62-1
86-57-7 7440-02-0
98-92-0 2820-51-1
59-67-6 177 37-65-4
4726-14-1 1836-75-5
614-95-9
13010-U7-4 7632-00-0 89-25-8 372-75-9 79-40-3 1120-71-4 S7-57r8 1955-45-9
BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS ' BOS BOS BOS BOS BOS BOS BOS BOS
BOS BOS BOS BOS BOS BOS BOS BOS BOS
BOS BOS
BOS BOS
.NCI-
CHEMICAL NAME
C04068 C05Q89 C902 26 CO 17 9 6 CO 562 9 CO 5561 C03963 C05903 CO 2948 C02904 CO 3 30 5 C02482 C0 32 92 CO 24 93 CO 4160 CO 39 41
C05890 C03316 C03930 CO U159 CO 22 22 CO 22 33 CO 5914 C05925 C00588 C04922 CO 49 2 2 CO 297 1
CO 3612 CO 59 3 6 CO 360 1 C00237 CO 5298 C02813 C02824
OXYCARBOXIME
.........
.............................. ...... _
BETA-OXYPROPYL-PROPYLNITROSAMINE
P'A. \ 1 *i ION
PHENANTHRIDINIUM, 3, 0-DIA MI N0-5-METHYL-6-PHENYL-, BROMIDE
PHENETHYLAMIHE, ALPHA-METHYL-, SUIFATE (2:1), ()- ...............
PHENICARBAZIDE
PHENOL, 4-AMINO-2-NITRO-
_________
. _________________
PHENOL, P-METHOXY-
.....................
...... ..
PHENOL, 2,2'-THIOBIS(4,6-DICHLORO)-
PHENOL, 2,4,6-TR1CHLORO-
H-PHENYLENEDIAMINE, 4 CHLORO-
M-PHENYLENEDIAMINE, DII1YDR OCHLOP IDE
O-PHENYLENEDIAMINE, 4-CHLORO-
O-PHENYLENEDIAMINE, DIHYDROCHLORIDE................................
O-PHENYLENEDIAMINE, N1(TRIS(HYDROXYMETHYL)METHYL)-4-NITRO-
O-PHENYLENEDIAMINE, 4-NITRO-
P-PHENYLENEDI AMINE
P-PHENYLENEDIAMINE, 2-CHLORO-
P-PIIENYLENEDIAMINE, DIH YDROCHLORIDE
P-PHENYLENEDIAHINE, N,N'-BIS (2-HYDROXYETHYL)-N-METHYL-2-NITRO-
P-PIIENYLENEDIAMINE, 2-NITRO-
P-PH ENY LENEDIA MINE, N-PHENYL-, HYDROCHLORIDE
P110R ROL
PHORBOL ESTER
PHOSPHAMIDON
PHOSPHORODIAMIDIC ACID, N,N-BIS(2-CHLOROETHY L) -N!-3-HYDROXYPROPYL CYCLOHEXYLAMINE SALT
PHOS PHOROTHIOIC ACID, 0,0-DIMETHYL 0- (P-NITROPHBNYL) ESTER
PHTHALAMIDE
PHTHALAZINE, 1-HYDRAZINO-, MONOHYDROCHLORIDE
PHTHALIC ANHYDRIDE
PICLORAM
PIPERIDINE, 1-NITROSO-
PIPERONYL BUTOXIDE
<
PIPERONYL SULFOXIDE
5
CAS #
5289-89-1
56-38-2 518-67-2
103-03-7 119-34-6 150-76-5
97-18-7 88-06-2 5131-60-2 541-69-5 95-03-0
99-56-9 106-50-3 615-66-7 624 -18-0
5307-14-2 2198-59-6 17673-25-5
297-94-4
298-00-0 85-41-6
304-20-1 85-44-9
`1910-02-1 100-75-4 51-03-6 120-62-7
SEGMENT
DOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS BOS _ BOS BOS BOS BOS BOS BOS BOS DOS DOS BOS BOS BOS BOS BOS BOS BOS BOS _ BOS BOS BOS BOS BOS
HI 9 CHEMICAL NAME Z02595 POWDERED PYREX
:04897 ;04079 :oosoo :06U40 :0 461 5 :03905 03076 05958 :01785 :0 3907 03839 03509 01672 05969 '05356 05947 05970 04659 00760 02506 06097 00362 02744 04295 04308 04284 05961 06451 04057 05992 04320 01503 06462 06473
PREDNISONE PROPANE, 1-CIILOPO-2-NITROPROPANE, 1,2-DIBROMO-3-CHLORO1,2-PPOPANEDIOL, 3-CHLORO-
*
PROPENE, 3-CHLOROPROPENE, 1,3-DICHLORO-
PROPIONIC ACID, 3-NITRON-PFOPYLHYDRAZINE HYDROCHLORIDE PYRAZINECARBOXAMIDE PYRIDINE, 2-(CHLOROMETHYL)HYDROCHLORIDE
PYRIDINE, 3-(CHLOROMETHYL)HYDROCHLORIDE PYRIDIHEACETAMIDE, THIO-
PYRIDIUM PYROGALLOL PYRROLIDINE, 1-NITROSOQUINOLINE, 8-((4-AMIN0-1-METHYLBUTYL)AMINO) -6-METHOXYRESORCINOL RETINOL ACETATE
RETINOL,ALL-TRANSSACCHAHINE SACCHARIN, SODIUM SAFROLE
SALICYLIC ACID ACETATE SELENIC ACID, MONOSODIUM SALT SELENIOUS ACID (H2 SE 03), DISODIUM SALT SELENIUM OXIDE (SE 02) SEMICARBAZIDE,MONOHYDROCHLORIDE SEMICARBAZIDE, THIO
'
`. ....... *
....... ' '` ' "
SILANE, 2-CHLOROMETH YLALLYL,".......... *, SILICONE OXIDE SILVER
SMOKE CONDENSATE-CIGARETTE SODIUM AZIDE SODIUM SULFIDE (NAHS)
< o
o
*`l
CAS ft
SEGMENT BOS
53-03-2 BOS
'
2425-66-3
BOS
96-12-8 BOS
96-24-2
BOS
107-05-1
BOS
4 542-75-6 BOS
504-88-1
BOS
BOS
98-96-4
BOS
BOS
BOS
26414-86-8 BOS
136-40-3 BOS
87-66-1
BOS
930-55-2
BOS
90-34-6
BOS
108-46-3 BOS
127-47-9
BOS
60-26-8
BOS
81-07-2
BOS
128-44-9
BOS
94-59-7 BOS
' 50-78-2
BOS
10112-94-4
BOS
10102-18-8
BOS
7446-08-4 BOS
563-41-7
BOS
79-19-6 BOS
BOS
BOS
7440-22-4. ii
BOS BOS
26628-22-8 BOS
16721-60-5 BOS l ! llll .
Ndl # * CHEMICAL NAME CO 026 0 STANNANE, HY DRO XYTRIP HENY L
T -- "V
`"'MW''
....................................................... ................ ......... `.............
CAS # 76-87-9
SEGMENT BOS
CO 2722 STANNOUS CHLORIDE .............
*"
C02459" U'-S x lLBENAHINE, 2,5-DIMETHOXY-
................................................................................. ' ...........
C072U9 STILBEiiE
COU 9 11 STILI3 ENE, N, N-DIMETHYL-4-A MI NO-
.............................
........................
CO 3623 STILDENE, 2,2',4,4',6,6'-HEXANITRO-
CO 2 2 11 STYRENE,BETA-NITRO-
_ __ ________________ ________
C03827 SUCCINIC ACID, MONO (2,2-DIMETHYLHYDRAZIDE)-
C02562 SULFURIC ACID, CADMIUM SALT (1:1)
...................
CO 6008 TALC
C02857 TELLURIUM, TETRAKIS (DIMETHYLDITHIOCARBAMATO)-
C07261 N-TETRADECANE
C02471 TETRAFLUORO-M-PHENYLENE DIAMINE DIHYDROCHLORIDE
_______________ ______
CO 6 5 75 1,1,3,3-TETRAMETHYL-DISILAZANE, 1,3-BIS(CHLOROHETHYL) -
C 0 3 0 6 5 THIAZOLE, 2-AMINO-5-NITRO-
_
..
CO 1809 THIAZOLE, 2-AMINO-5-SULFANILYL-
C00566 THIO DANE
' ; * ` ' > ` ` ' l' ` ' 1 " 1
CO 4 55 7 THIOPHENE, 2,5-DIHYDRO-,1,1-DIOXIDE-
CO 1 64 9 THIO TEPA
____ _
__ . .......... ................ ......... ....... ,, .....
CO U 2 51 TITANIUM
............... ...
C02504 TITANIUM ACETYLACETONATE
COU240 TITANIUM OXIDE (TI 02)
C04502 TITANOCENE DICHLORIDE
CO1810 P-TOLUAM IDE, N-IS0PROPYL-ALPHA-(2-METHYLHYDRAZINO) MONOHYDROCHLORIDE
C02302 TOLUENE-2,U-DIAMINE
___ _
_ ............
C013 32 TOLUENE-2,5-DIAMINE, SULFATE
CO 1865 TOLUENE, 2,4-DINITRO-
C023U6 M-TOLUIDINE HYDROCHLORIDE
CO 20 51 O-TOLUIDINE, 5-CHLORO-
CO 2 3 6 0 O-TOLUIDINE, 4 -CIILORO-, HYDROCHLORIDE
CO 2335 O-TOLUIDINE, HYDROCHLORIDE
C018 43 O-TO LUIDINE, 5-NITRO-
....................................
C06020 O-TOLUIDINE, 4 - (O-TOLYL AZO) -
<
C02040 P-TOLUIDINE, 3-CHLORO
n
C02357- ,P-TQLDIDINE, HYDROCHLORIDE
0 . oo
o _ _____
__ .................................. .................... _ 4
fOo' ui -
"7772-99-8 BOS
BOS
588-59-0 BOS
838-95-9 i BOS
20062-22-0 BOS
102-96-5 , BOS
1596-84-5 BOS
10124-36-4 BOS
14807-96-6 BOS
30145-38-1 BOS
BOS
BOS .
BOS
121-66-4 BOS
473-30-3 BOS
115-29-7 DOS
77-79-2 BOS
52-24-4 7440-32-6
BOS
nos
BOS
13463-67-7 BOS
BOS
366-70-1 , BOS
,95-80-7 BOS
6369-59-1 BOS
121-14-2 BOS
, BOS
95-79-4 BOS
3165-93-3 BOS
636-21-5 BOS
99-55-8 ' BOS
97-56-3 BOS
95-74-9 BOS,
$*10-23-8 BOS
UCI' I CHEMICAL MAKE CO2153 ' p-tolylurea
C00259 CO 3441 C02391 C00373 CO 04 4 2 CO 3781
:01729. 704820 701490
CO 2119 703247 703805 701763 702846 701752 701774 704524 703816 702073 703792 703327 702777 702017 7021 86 703883 703894 703872 704319 700113 700453 704842 704864 706484 704013
TOXAPHENE
TRIAZENE, 3,3-DIHETHYL-1-PHENYL-
S-TRIAZINE, 2,4-DIAMI NO-6-PHENYL-...........
................ ............... .
S-TRIAZOLE, 3-AMINO-
TRIFLURALIN
`"
........................... "
TRIMETHYL PHOSPHATE _
_
____________________ ______ ___ ____
TRIPTOPHAN, 'L- ............
URACIL MUSTARD
URACIL, 2-THIO
.................... ..
UREA
UREA, 1 -(P-ACETYLPHENYL) SULFONYL)-3-CYCLOHBXYL- ^
UREA, (2-BROMO-2-ETHYLBUTYRYL) -
_ _ r -. c
UREA, 1 -BUTYL-3-(P-TOLYLSULFONYL) -......................... "
....... ~
UREA, 3- (P-CHLOROPHENYL)-1,1-DIMETHYL-
UREA, 1 - { (P-CHLOROPHENYL) SULFCNYL)-3-PFOPYL-
UREA, 1-CYCLOHEXYL-3- (4-METHYLMET ANILYL) -
UREA, N ,N*-DICYCLOTHIO-
UREA, 1,3-DIETHYL-2-THIO-
_ 1 'M " _
UREA, (P-ETHQXYPHENYL)- ............... ..................................
.........
UREA, 1 -ETHYL-3-(5-NITFO-2-THIAZOLYL) -
UREA, 1- (HEXAHYDRO-1H-AZEPIN-1-YL) -3- (P-TOLYLSCJLFONYL) -
UREA, 1 -METHYL-1-NITROSO-
UREA, '1 -PHENYL-2-THIO-
UREA, 1,1,3 TRIMETHYL-2-TH10-
URIDINE, 5-BROMO-2*-DEOXY-
--
URIDINE, 21 -DEOXY-5-FLUORO-
URIDINE, 2 * -DEOXY-5-IODO-
VAHADIUH
VAPONA
^ ........................
VEGADEX VINBLASTINE
c_
____
- o - ......................*
...... - -
VINCRISTINE VINYLENE CARBONATE VITAVEX
% g oo ro
....
CAS #
1319-80-8 7 227-91-0
91-76-9 61-82-5 1582-09-8
73-22-3 66-75-1 141-90-2 57-13-6 968-81-0 77-65-6 64-77-7 150-68-5 94-20-2 565-33-3 1212-29-9 105-55-5 150-69-6 1 39-94 -6 1156-19-0 684-93-5 103-85-5 2489-77-2 59-14-3 50-91-9 54-42-2 7440-62-2 62-73-7 95-06-7 865-21-4 57-22-7
5234-6B-4
SEGMENT BOS
BOS BOS BOS BOS BOS BOS BOS r i BOS BOS BOS BOS BOS BOS i BOS BOS BOS BOS BOS BOS nos BOS BOS BOS DOS BOS BOS BOS DOS BOS BOS BOS BOS BOS BOS--"
ttCI #' CHEMICAL NAME E00646 X OR GAMMA RADIATION
CO6031 ' XENON
.............................
CO23 13 2,4-XYLIDINE HYDROCHLORIDE
C02324 2,5-XYLIDINE HYDROCHLORIDE
C00544 ZECTRAN
C03929 `ZINC
CO 447 7 ZINC ACETYLACETONATE
C04400 ' ZIRCONOCENE DICHLOHIDE'........
CAS *
SEGMENT BOS
'7440-63-3
315-18-4 ,7440-66-6
' BOS
BOS BOS BOS BOS BOS BOS
CONFIRMED CASES OF LIVER ANGIOSARCOMA AMONG PVC WORKERS
COUNTRY
CASE
if
United States 01
United States 02
United States 03
United States 04
United States 05
United States 06
United States 07
United States 08
United States 09
United States 10
United States 11
United States 12
United States 13
W. Germany 01
W. Germany 02
Great Britain 01
Norway
01
Sweden
01
Sweden
02
BIRTH DATE
00-00-22 ' 00-00-34 00-00-15 00-00-24 00-00-12 00-00-29 05-03-22 05-06-20 00-00-31 08-16-13 05-27^09 ll-rl7-18 12-01-21 07-26-31 06-04-30 00-00-01 12-23-15 00-00-27 00-00-11
1st PVC WORK
12-09-48 11-15-55 11-28-45 07-06-52 06-19-44 01-37-62 08-00-44 10-07-46 05-28-45 06-00-51 1G-J4-46 09-13-49
08-19-44 10-14-57 10-01-57
00-00-46 03-00-50 00-00-51 00-00-45
'
DX ANGIO SARCOMA
03-00-71 05-00-70 12-00-73 08-00-67 04-00-64 02-00-74 00-00-68 08-00-61 03-01-74 05-00-68 Q3vG0-7Q 05-00-69 05-00-74 00-00-71 00-00-69 12-00-72 12-20-71 00-00-70 00-00-72
Note *00* indicates unknown date
AGE AT DX
49 36 58 43 52 45 45 41 43 55 61 50 53 40 39 71 56 43 61
YRS 1st PVC TO DX
TOT YRS PVC
22 16 14 13 ' 28 28 15 15 20 18 12 12 24 18 15 15 29 17 17 J7 23 23
20 ` 15 30 30
14 14 11 11
26 20 22 21
19 1.8 27 23
DATE OF DEATH
03-03-73 09-28-71 12-10-73 01-07-68 04-09-64 ALIVF 03-23-68 08-29-61 ALIVE 05-10-68 G3-_16t-7Q. 05-02-69 ALIVE 12-14-71 01-25-69 12-00-72 01-04-72 00-00-70 00-00-72