Document ZnX56Yd50QO97Bx4LovOaKYgp

June 24, 1966 Mr. Prank Bole Dleoast Foreman Briggs A Stratton Corp. N. lWth Street Milwaukee, Wisconsin Dear Nr. Bold Dr. Hoamer of our Chloago offloe has aeked me to forward toxicity and aafe handling Information for Pydraul A-200. Animal toxlelty studies with iiiri;espr4i$et have Indicated that the oral lethal dose (SDcq) to rats Is 10,500 milligrams per kilogram. The lethal dose when the material was applied undiluted to the unbroken akin pf rabbits is approximately We oonclude from the above that acoidental ingestion on the part of htssans la not a particular hacard In view of the high oral lethal dose in rate. Similarly, single massive akin exposurea should not be Immediately hazardous. The lethal dose obtained In skin penetration studies is suoh, however, that prolonged and repeated akin oontaot should be avoided beoause or possible systemlo effects. In addition, prolonged and repeated skin contact may lead to skin irritation. We also feel that vapor Inhalation should be avoided when the fluid Is heated to elevated temperatures. Such exposure again relates to prolonged or repeated exposures rather than short-term massive or acute exposures. In the case or the latter, workmen would not voluntarily expose themselves to concentrations that are hazardous beoause of irritation of the respiratory traot. The use of Pydraul A-200 in Industrial hydraulic fluid appli cations should not present toxloity hazards during the trans fer of the fluid from original containers to the hydraulic system. Obviously when the fluid Is within the hydraulic system, there should be no exposure and consequently, no hazard. In the event of rupture of hydraulic lines and MONS 091170 Hr. Frank Bolz June 24, 1966 Page 2 subsequent splashing or spraying of the fluid on the heated surfaces, vapors of the fluid and possible decomposition produote (depending on the temperature of the heated surface) may be Irritating If Inhaled to the degree that workmen will not voluntarily expose themselves to toxic concentrations. No hazardous exposure should result during the Interval required to shut down the system and obtain suitable respiratory protective devioes during repairs to the system. We would not anticipate any greater hazards during routine maintenance of a system containing Pydraul A-200 than would be present if the system contained a phosphate base fluid. It would appear to be good praotlee to wipe dry any equipment before doing any welding on surfaces whioh might be "wetted" with or have a film of either type fluid on them. If the above Information does not answer your specific questions please let me know direotly or through Br. Hosmer. Very truly yours. R. Emmet Kelly, M.D. Medical Dlreotor REKimJb co i D. I>. Hosmer, Monsanto, Chgo MQNS 091171