Document ZbJmjxZYN4MEqkDmOBJr8RQ8
FILE NAME: Union Carbide (UC)
DATE: 1956 Sept
DOC#: UC338
DOCUMENT DESCRIPTION: Industrial Hygiene Quarterly - Prepared Discussion Henry F. Smyth, Jr.
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Industrial
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ASSOCIATION
Quarterly
VATERLESS SKIN SER witU tke PAXI
VOLUME 17. NUMBER 3 SEPTEMBER. 1956
Q1ENE AMERICAN INDUSTRIAL HY
ASSOCIATION
liately
ing lied by a
Volume 17
SEPTEMBER, 1956
Number 3
er with
in vivaient
Symposium on T hreshold L im its
Present Trends in MAC'S ......................................................... Warren A. Cook
o O
The Need for Threshold Lim its........................................ Miriam Sachs, M.D.
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Prepared Discussion........................................................... Henry F. Smyth, Jr.
'ill have rial ;hemical
sound
irity
Methods of Establishing Threshold Limits................... James H. Sterner, M.D. Prepared Discussion..............................................Herbert E. Stokinger, Ph.D. Engineering and Chemical Application of Standards ... .Allen D. Brandt, Sc.D. Prepared Discussion................................................................ Arthur C. Stern Prepared Discussion ............................................. Theodore C. Waters, LL.B.
A utomatic I n strum entation for A ir P ollution Monitoring-- A P rogress
&
R eport on A uto m a tic Dir ec t io n a l A ir Sa m p l i n g .................William A. Munroe 298
f lesign,
>f ;ontrol of
tion.
A V ersa tile P ortable A ir Sa m p l e r ..........................H .S . Jordan and R. N. Mitchell 303
Determ in a tio n of I n tern a lly Deposited R adioactive I sotopes
from E xcretion A n a l y s e s ............................................................... Wright H. Langham Criteria for a n E valuation o f N o ise P r o b l e m s ....... Charles R. Williams, Ph.D.
F lo w Calibra tio n o f H ig h -V o lu m e S a m ple r s .....................................................................
Bernard D. Tebbens, Sc.D., and Donald M. Iieagy, M.S. 327
R ecent I ndustrial H ygiene Developm ents-- A Symposium
In the Field of Air Pollution......................................................Henry N. Doyle In the Field of Chemistry..............................................Ralph G. Smith, Ph.D. In the Field of Engineering...........................................Leslie Silverman, Sc.D.
In the Field of Noise.................................................................. Vaughn H. Hill
In the Field of Radiation.............................................................Saul J. Harris In the Field of Toxicology...................................Herbert E. Stokinger, Ph.D.
H y g ie n ic guide ser ies ..........................................................................................................................
P r esid en t's page ....................................................................................................................................
Selected T it l e s and A b s t r a c t s .....................................................................................................
B ook R ev iew ................................................................................................ ............................................ A I H A I n d u str ia l A sso cia tes, O f f ic e r s , D irectors, a n d Co m m i t t e e s ......................
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American I ndustrial H ygiene Association Quarterly, published by the American Industrial Hygiene As sociation in March, June, September, and December. H oward N. S chui.s . Editor; H erbert J . W eber. Advisory Editor; L loyd E. Gordon, Associate Editor; W illiam S. J o h n so n , Advertising Editor; P au l D.' H alley, Cir
culation Editor; A . D . Cloud, Publisher; D obis F lournoy, Editorial Assistant. Publication and Editorial O f fices. G06 North Michigan Avenue. Chicago 11, Illinois. Subscription *4.00 per year in the United States: $4.60 per year in Canada; $6.00 per year in other countries. Single copies, $1.60--except the June, 1966, issue which is $2.00. Copyright, 1956, the A merican I ndustrial H yoiene A ssociation. Entered as second class m at
ter May 3, 1948, at the post office a t Sheboygan, Wisconsin, under the Act of March 3, 1879. The A merican Industrial H yoiene A ssociation Quarterly reserves the right to edit all advertisements and to refuse advertis
ing copy when it does not meet the high professional standards adopted by the Association.
ber, 1956
ng of 260 we to be .cent with roentgens me week? ne within ve should larily be se the exunnecesworking below the ined with expense, w a pracrved--not ssing the er limits Even the some efen if the ' the in ult from prevent j should etectable ninate it
the im practice. ate, and aly as a ever has 11permit nan haz-
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Radiation 1955.
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Industrial Hygiene Quarterly
279
' . Prepared Discussion
which is recorded in some of the threshold limit values. Whether we want him to or
Dt
HENRY F.lSM YTH, JR.
not, he ( and that includes every one of us at
'
Mellon Institute
times) will use threshold limits as estimates of comparative toxicity to meet his urgent
Pittsburgh
requirement for finding some basis for opin
ion.
r . s a c h s has established that the vast To what extent is he wrong? A threshold
majority of our colleagues recognize limit based on comfort, irritation or good
their need for a list of threshold limits. Sheengineering practices certainly is not com
distinguishes between the need of the official parable to one based on pathological effect.
agencies for a screening device to apply to But the former limit is certainly lower than
thousands of industrial processes they en one based on injury. The error is on the side
counter in field work, and the need of the of safety if it is stated that material A has
private industrial hygienist for an engineer a threshold limit based on comfort higher
ing bench mark for planning and evaluating than that of material B which is based on
environmental control. To satisfy each of injury, therefore material A should be used
these needs vapor concentrations must be in the process.
measured under operating conditions before No matter which material is chosen it
the threshold limits values can be useful.
will be employed, by persons subjected to the
There is a third group which uses thresh same degree of industrial hygiene and medi
old limits and needs them because nothing cal scrutiny. By choosing the material with
better suited to the need is available. Every the higher threshold limit the probability of
one of our profession is a part-time member safe operation has been increased, even if
of this group and some are full-time mem the basis on which the choice was made is
bers. Reference is made to the arm-chair in not numerically sound.
dustrial hygienist. He may never measure a There is one "important short-coming in
concentration and he may never observe an this argument which points out an im
industrial operation. He uses threshold lim portant way in which threshold limits do not
its to advise upon the selection of a chemical meet the needs of the arm-chair industrial
for a particular application, to select a suit hygienist. If the volatility of a material with
able application for a little known chemical a high threshold limit is greater than that
and to bolster sales arguments for a chemi of a material with a low limit, then in a
cal or mixture of chemicals.
particular process the less toxic material
When the industrial hygienist is asked to may be more hazardous, because a greater
advise whether acetone, propyl acetate, or vapor concentration will be in the atmos
methylene chloride would be the safest sol phere.
vent in a particular application, it may be I maintain that the list of threshold lim
believed that his answer is based on a pro its is our best available source for judg
found knowledge of toxicology, but actually ments on comparative toxicity of vapors to
he recalls the threshold limits, or refreshes humans. It can be improved for this pur
his memory by consulting the list while the pose, but there is nothing better for us to
questioner waits on the telephone. Then the use. However, it refers to toxicity, not to
answer is given as if the list recorded com hazard. It is the single-phased toxicity of K.
parative toxicities, perhaps adding a bit of B. Lehmann. A table of comparative hazards
qualitative information on fire hazard and would go back to Lehmann's two-phased
type of injury from an excess.
toxicity by combining vapor pressure (or
What better data are available for the evaporation rate) with toxicity. This table
arm-chair industrial hygienist than the an of comparative hazards is what the arm
nual list of threshold limits ? He must have chair industrial hygienist really needs. It
some guidance if he is to do more than toss a would go a long way toward satisfying all
coin. If he is given a list based on uniformly of his needs, particularly if it included in
conducted animal experiment, he is deprived formation on nature of injury, on the penal
of the benefit of the years of carefully ob ty for exceeding the limit and on the degree
served and evaluated ' human experience of hygienic urgency for observing the limit.
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