Document ZBd17ZYpK1gzLdMXDaaOb1xGJ
FILE NAME: Asbestos Mining (ASMI)
DATE: 1928 May
DOC#: ASMI002
DOCUMENT DESCRIPTION: Journal Article - Pulmonary Asbestosis in South Africa
fAY 26, ] 1928
PULMONARY ASBESTOSIS IN SOUTH AFRICA.
r
T lt r pRfTTSIf MRDtciL Journal
885
UIAIONARY ASBESTOSIS IN SOUTH
b(Fuitg.ev7e).n Plahraggeocloydtossiswewroas sneoetn, cocnofminpeldetetoly(heen. cslmosaelld.-rapn.diHoicillic,u, bent order to allow them to occupy the space within the
AFRICA.
(With Special Plate.)
ctoegllesth1e(11frigw. ith7).theItcrywsatsallitnheoumgahltleithamt aytbhr-aeve fobereeingntheliodio-. of the fibrosis, as tile connective tissue, both in distribuutiioi,n,i
BY
F. W. SIMSOX, M.B., C'h.B.Fd.,
aanddusfot romcactuipoant,iownaosf vtehrey lsuungggse.stiAvet ofhfocshaamngeestimreesullitioingInstrtoemre of pneumonia and protracted recovery must be taken mlo
lOLOG'OT AT THE SOUTH AFRICAN IN STITUTE FOR MEDICAL RESEARCH, JOHANNESBURG.
fciobnrossidisciiastinoont, asiilnucnecoamn muonnreosocelvined1cnpeneeuammoonngisat, vnialltiives-ubwseoqrkuienngt
ias ' on known for some time th a t workers exposed on tho mines in South Africa.
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chde inun-ithve partmepoasrpahtieorne oafrisaisnbgestforos mmastoemriealsprsoucfefsesresfromm ConsultatioCnasoefs tihiei arnecdoridvs (aNnods. p6re4c1i9ouasndhi6s7to3l1o).gical si'' m->
r10o1h1male\v dniosat bailitsyo.urcTeheof mdiannignegr, onfs thasebemstoinseriasl mitisneeldf ocafsems,atbeortihal oifrowmhicthheshsoawmeed mloibnaer phnaseumreovneiaal.ed Ttwheoreavdtah-i m\en,.iir
Jey roicnk owpheinch qsutiifllmecos.ntaAinfstefribrseoritningp,aytahbelere qureamntaiitnys. Jung of this rock causes a considerable degree of dust
l(ilt'itgle. 8c)onannedctivreeiraticstsiulee cirnycsrteaallsien,e bpuatrticthlees uwneurseuaplr-..setinmt. ,m\'1ns ohfisttoheryseocfasleesn.gth of serene in the null was oblamed with either
1sueixea, gganerdateedxpionsutrhee tcoartdhieng daunsdty spatimnnoisnpgheorfe asisbessttoilsl ic mil!-.
vaFriuertytheofr s.hsatupdeys, hofut tthhee mgoolsdtencomyemlloonwfohromdsiohsadslilnovo.nrdl oda
s iyoflipttelresoncos nwceorrnkiningg twheithpaatshboelsotogsicalilaschbaenengesfouinndthilel oarfincelulyb-pshoainpteedd tcauidl s aTnhdey aw seeegmnoenn-teredfrabcotdilve ttoappeorilnag'I/:to.1
whiimngincali-rees, maingdht ibto wofasinttheoreusgt.ht th a t a record of the tluigrhnte,dsoblulabclke mandstrtoenngdeadt itdos,loasned,thoenirraoiustilninge,to ain1osdethtloo,.r:-,
1 iSnepStoeumthbeerrn2nRdh,o1d9e2s6ia, tfhoerwmaerddiecdaltoofftihceer Soofuatihl aAsbfreisctaons tfreeraroteedvamwditeh hthoety dilguatvee Inadrowchelllo-miicarkaecdid Panrudsspiaonta-sbnlnue1
.1tuatepolostr-mMoerdteicmalcRaseesefaorrchhitshtroeloegsimcaalllesxpaemciimnaetnisono.f lung rireoanctiroena.ctioNno cpoiuglmd ebnet doxe'tceocpttedtlminsothsetruscectutiroenss geixvainmgintehde
C i (No. 9026).
Sprterosenngce hoyfdriorocnhloarnicd faocuidn,d nheagvaintigve,beweans utesestdedto fdoir--otlhvee
ee smubojnetchts wmas thaemaaasslbeeesatdosultmnilal,tivaen,d,wheoxchepadt fwororkaedshfoorrt i before his death, had had a good record of health,
othuot hiryodnrofcrholmoricfreaschid segcatvioensa. veAryftedristtrienacttinrged-tphienkseecotiloomnwith potassium thiocyanate, and the red-pink colour di-
n'si.neanwdee(khse bpeofsotr-emodreteamth fbinedinsugfsfersehdowferdommialciaurtye ttuubbeerr- involving the lungs, liver, spleen, and pericardium. The
Taphpeesaercetdionosn wthoerearded-eitxioanmionfeda asonldutsihoonwoefd mthcaret itnhiee mchalojorirdite.
1t8woasf a(nhye evhiidsetonlcoegiocfalfiberxoasmisininatitohne lwunagss twohicahscemrtiagihnt bief othfestheetegsotsldeint wyealslowconbcolduideesd htahdatbetehne dsitsrsuocltvuerdesoucto.ntaPirnoemd
telymailslcrairbeedextpoostehde tnoataurveeroyf hdiussteymaptlmoyomspehnetr,es,ince workers
a largo percentage of iron. As controls, sections of lungs from a large number of
awrt lufrnogms tshheowteudberacucloerstiasi_nandamaosusonct iaotefd cfoinbnroescitsi,vesectitsiosunes fe which had no obvious connexion with the tuberculous
cmuilnoesirss wonerotheexRamanindedw.hoBhoaddiesdiseudchfraosmhsaivliecobseisenanddcstcuiibbecidabove were found in nono of these, nor was tho Prussian
s`ds. stIrut ctwuaress,alwsoithforuonudndtehdatofcucrluiobu-sshagpoelddenendysell(oFwig.se1g)-, embedded in this fibrous tissue, together with very minute,
bcalusees rewahcetiroenthoor optihgemr etnetst wfoasr iorbovniopuoslsyitivoel ehxaccemptatoingctnlioou-us
v ughretfhreactciulerioupsarstiecglmese,ntetdheboldaiettserwepreresruemmaabrklyed suipliocna,, ohraidginw.orkAedsifnogrletweaesnetyo-feiaghmt iyneearrswains athlsoo himaeemstaimtitaetemdi;nleise
fiortrhmeerd infvibersotuigsattiiosnsuewaws acsararitetrdibouutte.dattothethetimper,esaenndce thoef ian qthueartNerortyheaorfs Fi/niigtlhame l,goalndd msuinbesseqoufenttlhye fBoransdev, enSoauntdh
w' as not until SCepasteemibi e(rN2o9. th1,101196)2.7, when a portion of from a second case was sent by the medical officer from
Ablfardicdae.r. TMhoaccroasucsoepioclalldyealltiho wpualsmocaniaeriynolmooat ogflanthdos wgaolrln enlarged, pigmented, and fibrosed. The pigment was dink
aimnveesmtiiglla,tetdh.at Tthheis fpoireeciognofboludniegs wanads ffriobrmosias mwaelree amdourlet wruistth-codlioluutreedhyadnrdochglaovreic aarmidaraknedd pPortuassssiiuanm bfleune ocraeaacutiiiolen.
e, wAhboouhtadSebpeetenmebmerp,lo1y9e2d6,inhethew- masilladfomritatedpertioodhoofsptiwtaol
Oseccctaiosniontahlo
rulsutn-cgoslosuhioewdodsu
ha p
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isdlieiftstiswo erfoibrvoissiisblea.n
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ed, afntodiitlaptenreu(mSeopntieam, baenrd1h9athd, a19l2o7n)greilaldnemssit.tedHien waadsydinisg tion. HS was very emaciated, and had (he physical signs
ifreown larregaoctaiorena.s oHf ifsitboiloosgisi.calThseecwtiohnolso loufngthgoavlearagomnairkeeailshowed moderately well defined, but irregulaily shaped,
ifhirnmonlyarbyotuunbderdcouwlonsisbywaitdhhefsiibornoss,is.theArtooatutgolpasnydstheenlalurgnegds <hrd, and the lungs on section hard and fibrous with an
Tmhaosseaslveooflawr ewlla-lflosrmweedre ascliegllhutllayr thfiicbkroeunsedt,isasnude t(hFeirge. w9ais
itelreaabtlhyere-nlilkaergceodn.sistence. The me'senteric gla.nds wero also ablomododveerassteelsdeagnrdee borfonccohnin. ecAtivelartgisesuqeuiannctrietayseofropuingdmethnet
itrooluosgictahlicskeecntiionngs sohfowtheed aplgeeunrear,altirzaebdehcuultaem,odaenrdatealdveegorleaer I n ' addition, there was a much more marked fibrosis
oanf da lryeidndgishfr-eberowinn aclovleooulir, waalvsecoolanrtawinaeldls,111anpdhabgeotcwyetiecn cethlles fibres of the newly formed fibrous tissue. The greater part
?evdascinulairrresygsutleamr-shaanpdedbrnoondchdil.es,Tchhisieffliybroruelsatetidssuteo wthaes at, the elements arranged in an irregular manner, and
owfasthaisnoptihgemr evnatrigeatvyeotfhepignmonenrte, aicntiomnu.chTsnmaadlldeirtioqnn,authtietrie,
(edrseosmemb'-l*amncaell'ltyompthheocoyrtidceralcyc,umwuhloartlieodnsa(rFraing.ge2m).enTt haenrde iwnasthientifmoramteloyf mcrixyesdtalwliniteh rtehferaicrtoilno-copnarttaiicnlein-'g. dTuhsot. laTttienr-
7i*0?d-eefiInfitionofof the sicliactoatrirch.nilodcuhlaeng(eFsi,g.an3d), mTahney borfontchhei wluhnegthwerastheespseacmiaellypeceuxlaiamrinbeoddietso wdeereterbmeiinnge, foirfmpedossfirbolme,
iW'foaisn*ng?o*4cedvid"ednucest ocfeltlusb"erfciullleodsiswoitrh apchuatgeopcnyeteudmopnaricticcloens.ypM. ' Embedded in the fibrous tissues, lying free in
adudset powshiticohf cfeornrtiacinierodn bdouthst afesrrionustheanedasefeomf ean iarosbne.stoAs careful and thorough scareli va- made, hut no partiile-
Won(Fsgigo.b4lr)u, and conta.i.n...e.d.. in P
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88 M a y 2 O, iqS]
PULMONARY ASBESTOS1S IN SOUTH AFRICA.
Tux B * it tm
JdtW CA i. J*WWA*
, xl fuuinnh tlio findings of Sir Kenneth Goadby1 and HiInCaidodnimtio,2n to the human lungs showing asbestosi,s, Dr. Aiie!.stt\MiuMjm-ioi dlaialso soutppthlieedSomuethwAithfritchaen lIunnsgtsituotio afogruiMneead-ipciagl waslbiueshtosdisie.d TihnisDaenciemmablerw, a1s92e7x,pofsreodm tocaaunsesasobethsteors tdhuasnt ahtomuorsspahedraeyeoxnpeeraimchenotfall!ivft.v Tdhae>sl.engTtihmofliresxi peoxsuproesuwieastotwook optlatthee osnamFeobyeruara.iy T4hteh,as1b9e2s5l,ifoarnmd ctohmepolausntd ounsedApfroirl t1hset SexouplehriemrnenRtsh'wodaessian. chHryissototilloeg*icoalbtaseincetidonsfrosmhowtheed ma,inseligihnt gneitneerieasitmiuegd tfeiabrtonsiios wanads tahne mpeersceamsee mof pthigemgeonltd,enhuytelltohwo hhuulmioasn {pKuiigm. on1.1u)y, assiibmeslatoisisto. those seen in the lungs o^f tuAuiiatolmapniamnsaol nshboewtwedeetnh atthethehufuibmronsicsawseass amnodrethueipeidxpaenrida,\ntiemuas!].\e Tihnis thies hreuamdailny ceaxsepslaitnheadn biyn tthhee edxifpfeicriumltyentianl picodwmdeinr,g atnhde ttooutghhe apsibeessctnocse foibfrea tocoma paurnaitfiovremlyly smfianlol apdiojepsotirftoiornm ocfotmhoporuoncdks.dusFtowr h"icdhuisstinusgua"llayniamssaolcsiaateldimwitiethd apmroopuonrttioonf cdounstat iniss pavaartiilcalbelse, ofansduffoifcietnhtilsy osnmlyall adismmeanll ssiiolincsositso' tphcoi msiizl e ooff tthheeirmraejaocrhitiyngofthtehe lupnagrticallevse5oliw. hiIcnh llueancgh, tmheentailovneeodli aisbobveet,wetehne 1p,uaratincdles3(ua, pipneatrhelahrgaeerm, abtiutet .thvoosne hporieopaaiored mfruocmh assmbeasllteors tfhoar n" tdhuestgirnega"terexnpuemrimbeerntos,f ainn athsbeeswtoosikdinugst matimll otshpehecroendpirtoiodnusceadrcexvpoeir\imdeinfftearlelyn.t fFrionme dvueisyt isfinceonptianrutioculselsy riecmacahiningsuthspeeantdmedospfhoerrea, nayndleonngltyh thoof <tiomnce-. nTtrhaet-ieougiaids uraellaychiende,icathseenm rneummabinersmuonvteil oar mleasxsimcuomn sintaonrtdedrurtiongprowdourckeincghahnoguerss.m Teximpesriimt ewntialll haenimseaelns sthhoawt, i.inng atthmeo's-apmhoeiedeagprpereoxoifmfiabtrinosgisthinatthoof tshaemewolernkigntgh mofilltimwiel,l haTveimto ahmeooubnttainoefd. fibrosis in two of the human cases p(Creasmri',noi oafnadsbjeis)toswadsudq,uitthee idneiftiinailter,ataendo,f pirfodduucotioton wthaes monpitdhewhRenan(do.mpIaticids wdiifthficputletxetont-sdtaaytenoan-dmeffoin(ittievetismileicofsoisr inhoen-pmriood<uucvtieonsiIonfosamn, abpuptremcoiadbelren doebgsreeie\ aotifonfibtreonsdiss mto sphuorwe/ athmatodietl aistchin mthaerkendeigfihbbroosuirshhoaodd taofketnenplyaceearas.fterInonCeayseeari i(-lmIovmo'-i.k Iint itsheknnouwlln, thhuatt tthhies wraafse coofmfpilbircoautesdtibssyuetujbireoi-dbyiuDinotnern'iouns`,i\ bmutudeivegnieaaltleorwiinngdufosrt dibisiesastehsecocmonpnlieccattievde atiss-uilel! umn oicilasodemfinCiteasi'fibi rowsaiss raafpteidr, twion yCeaasres noithweroerkwains ilul1bnluulrlewittlhii-nowom\ kidenwcaes oicotumbpelrectuedlosiDs.is. Cooke,6 S tuart pMu(liRhoonnaalidv, aasnhdesOfolsiivse,r7anpdubplisuhsediontshetior tphaapteras dsheoatlilngaitwieitlhe ohnd utliireisi.ui1H1ioMuibnje'i !dcaspMpeibaelded ainndthoeiii/nAiwiuarst. suTspheec-temdnlwaihietyn tthine IIimimdmagit-u. leAaspmpeatllieod-,r alnodcoordmedwhoierke,g'itchse faasrbteostocsondfiunsat aiex(pIannwsi)btlielr.foi Wfluh'et(hluemr gCoNthemr athseheslutintogrsmm etohmepiroucmasles waraes
q,.the i<oiapppieoadlisli fmugheIInl' ice<haonugleosf itaujs\ ismucphoss(i{bnles toin stahye, In litiee l Mioii oi Sonili Afina* and Rhodesia there are mobatna\ineadsbeh-utots twmoinoesth, erfroimnterseusmtiongof\arwuinlcihes calrnegsfoottulned isntivaeml;e, h,icccciontnddoilsilceovcainvd, atimn*oscithce.miAstinyiosoifte wishicah cohamspanroatsiiiemenilaer(,mto|detc(rdoi')eiwdooliikteed inout(,(imhuptosiittiaopnp. ealsRoloth bethseosme eweohmat-'
poof ufnodusr csoanmtpailnesaolfaragmeopsietroc8enshtaogweedoftbffettrwrqeneisi i3r%ona.v.dAp4a4lip^*s
c1e6n.5t, anodf F40e.O5, pearn dc1eenitg. htUspamtoptlhese'opfrecsreonetidtohleitree* hbaisrtwWee
ndoeatehxaammionnagtiothnosoef wpoorskt-inmgoritnemthimllsatwerhiearle ftrhoeisqe cmaisneesra*
arcChtrrye.astoetdil.e oNr osesrupcehntminaetearsibael shtoass ubseueanllmy acdoentaavinaisla2blteo.
panearlycseinst,ofofDrF.eCOooiksoe'ms ocrapsheosuhsolywerdep3lapceirngcemnta, gonf eFweO^, aTi1
t2h.4e4 Rpheor dceesniatn. mDirn. eMralc,Oraacocoorfditnhgo tGo ovMerrr.miAen. t LC.lieHmailcl
Dasnbheostroastoruys,edJobhyanDners. bMuragv,roangoalryds&etdo thine FhiesOacnoimntaelnt of .t!
mApenptasr,enatnldy feovuennd waitmh uvcehryloswmearllpeprecrecnetnagtaeg--esnaomf e'Elye,O0-4
goWldeinthyerlelogwardbodtioes tahree fuonrmuseudalinsttrhuectluunregs.and ch..c,inic
npualtmuroenaorfy thaesbgesotlodseins, yuelnlotiwl bmoadnieys mfoourned ciansesthehalvuengba#-
elixttalme incaend abnedsmtaoterde.exTpehreirme einstanlowdoorkubhtasthbaetenthedyonaervee'
spoamrteicwulaayrlyasswoictihatetdhewFitehOthceonatsebnets,toesi,thoerr, opfrotbhaeblyas, bme$
ihtisgehlferorpoefrctehnetadguest ooff tihroenm, iwll.hicTh hims adyusbtecodnetraiivnesdftpmsuuj
froTmhrtehee ploodsseibfriolimtieswhreicghartdhiengasbtheostofsorims matiinoend.of'the gold-
*yel(l1o)wInbodthiees faorremwoofrthay goefl,maesntsiuogng:ested by Dr. Stua
Mc(2D)onAasldp.articles of ferruginous quartz formed i,n the jun
quundaretrz ccohnadnigteiodnsin scimomilparosittoionwaesataherreinsgu,lt oorf cfoemrrbuigniant^u
wit itmh acyonbsetitmueennttisonoefdththeabt ocdryoefilduoidlist.e, Iwnhiscuhppisorat nofalktli
stiiolincawtehewnitehxpfoersreodustoirwoena,thisereisnpge.ciaSlloydiluiambleis troemdeocvoemd,pot;
isreotn froexei;dizthedereantdhehnydrreastueldts toa ffoerrmrugilinmouosnitqe,uaartnzd wsillml
pIot sissesesxestrethmeelfyinehlayrdfi,braonuds csotrluoucrtuedreaorficthhegoorldigeinnaylelmloiwne.r;'
iqsupaonstsitiybleofthfaetrroaucshairnogne assuscohciaastetdhiwsitohccculnrs-ywsoittihle,thaendsntul
co(l3o)urPohfagthoecybtoosdiisesofinththesee lustnrgusctiusrevseriys saugvgeersytivpero. mine);
tfheeastue rceelilns mthaey lhuanvges, baenedn riet swpoansstihbloeu, gfhirtstt,hfaotrthsoemaectcihoanrt;
in chemical composition, then a building up and mouldfr
intTohethefibvraoruiosustissshuaepeschsaenegne. in the lungs of the aboVj-
tmheenrtieosnueltd ocfaasesreaocf tiwonorkonerstheinpaasrbtsesotofsthmeiltlisssuisesprtoobbag}t
thoSugfofilcdieenntyeclalosews boofdiepsulamnodnaarysmaasllbeqsutoasnistityhaovfe sniloicta.b*#
riencfeocrdtieodn tboybaspseeciafnic oipnifnliaomnmuaptoonrythperoclieasbseilsitysutcoh saescotnudtk*
creucloosridse, d,buwt hiitchishavveery bseuegngeesxtiavmeintehdat htiwstooloogficatllmly-,e ha'
sahnowasnbetsutobserdcuulsotsioscccuopmatpiolincaotifngthethlouncghs.anges produced,I]
favBoeusirdeosf tuthbeesreculcoassiess bethinegroa icsomstpilllicaftuinrgthfearctoevr.idence*#*
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cul1o11sis1. 910 Dr. Collis10 reported on the relati.onshi.p -'if
5asbdeesattohss dfruosmt tpohtphuislims ohnaadryoctucubrerrecduloinsisf,iveanydeafiosuanmd ong
a staff of less than forty workers employed at a facto#
vhete asbestos is woven.
foiIn dcaotnacluasniodn,mIatweirsihal tofrroemcordanmyextphearnimksenttoalDra.mMinaavkrogto W
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ltuhnogsRooOf caonhteanetmoaftitae smaminpeler; oftoasDbers. toMs;cCanrade toforMrh.isP.anLaolnygsmisor
for las valuable assistance in preparing the microphotograpns.-,
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