Document ZB5XYBaGNb50VxYdD9B8KbD2L

fcl ! O0 c=a Industrial Hygiene Digest April. 19f 377 General Immunological Response and Disease Incidence in Workers Exposed to the Action of Carbon Bisulphide. L. M. Kashin. Gigiena i Sanit. 23-26 (June, 1965). Russian. An attempt was made to determine the effect of Bmall concentrations of carbon disulfide or immunological reactivity of the body and on morbidity with temporary disability in worker! a rayon factory. A drop in general immuniloglcal reactivity and a rise in morbidity rate ' observed in workers exposed to the action of carbon disulfide at concentrations both above below the maximum permissible level (lOmg. /cu.m. ). A relationship was demonstrated'b tween the state of general immunological reactivity and that of morbidity with temporary disability; the morbidity rate dropped with a rise of body reactivity. - Aerospace Med. Ab 378 Dynamic Investigation of Adrenal Cortex Function in Subjects with Symptoms of Benzol Poisoning. A. Cavallerl and A. Saivadeo, Lavoro Umano 17, 165-171 (April, 1965). leal: The adrenocortical function was studied in eight patients between 20 and 59 years of age wi hematological symptoms of benzene poisoning, and compared with data from an equal numb of normal subjects between the same ages. Basal values of 17-ketosterolds and 17-hydrox qorticoids excreted In the urine were found to be almost identical. The response to exoger. corticotrophin (ACTH) was lower in subjects with symptoms of benzene poisoning, but the difference was not statistically significant. These data indicate that no significant change i adrenocortical function occurs during benzene poisoning. -- Aerospace Med. Ab 379 Hazards of Insecticide Applications in Quebec. Z. Jegier. Can. J. Public Health 56, 233-238 (June, 1965). A comprehensive two-year study was made commencing in 1962 by the Research Institute o Industrial Hygiene and Air Pollution of the School of Hygiene, University of Montreal, of us of insecticides throughout Quebec Province with emphasis on occupational health hazards ai routes of entry such as oral, respiratory, and dermal in persons applying insecticides by o door and indoor spraying. Although Indoor applicators were frequently exposed to above cu rent threshold limit values, the maximum recorded exposure value was but 1.4% of the toxi dose (systox) because of the short duration of the spraying cycle (Durham and Wolfe proced' on dermal LDgg). Carelessness and unfamiliarity with the dangers of toxic materials were encountered throughout the survey. Indoor spraying in greenhouses and cattle barns, and its effect on professional exterminators in various areas, such as restaurants and hospitali that utilized lindane vaporizers were investigated. In outdoor applications, both ground ap plicators and aircraft pilots were surveyed for respiratory and dermal exposures. Respiri exposures were calculated from: (1) air concentration values and an assumed lung ventilati of 444 liters per hour; and (2) from respiratory filter pad deposits. Dermal exposures we: determined by absorbent pad collections (Berkow's method). Mean respiratory exposures t malathion, sevin, parathlon, and guthion during air blast spraying were 0.08, 0.29, 0,03 a 0. 26 mg. /hr. , respectively. Pilots' mean respiratory exposure to endrin was calculated ai 0. 01 mg. /hr. Only 11% of workers used respirators; 48% had no protection whatsoever. A hospital kitchen test on continuous vaporization of lindane disclosed a threshold limit value above 0. 78mg, /cu.m. The necessity of vigilance during application and with regard to chr rather than acute effects is indicated by the study. There are 11 references. Public Health Eng. Absts. 380 An Approach to the Separation, Identification, and Determination of at Least Ten Oraanophosphate Pesticide Residues in Raw Agricultural Products, D. F. McCaulley. J. Assn. Offlc. Agr. Chemists 48, 659-665 (June, 1965). This paper describes the preliminary developments of a method that permits relatively rap qualitative determination of residues of a number of common phosphate pesticide compound! Extraction is followed by vacuum sublimation, gas-liquid chromatography, 'and infrared ana sis. A wide variety of vegetables and fruits can be analyzed by the general procedure. Public Health Eng. Absts. 381 Sequelae of Acute Organic Phosphate Poisoning. I. R. Tabershaw and W. C. Cooper. J.Occ. Med. , 5-20 (Jan. 1966). A group of 235 individuals reported by California physicians as occupationally poisoned by organic phosphate insecticides during 1960 was selected for a study of possible sequelae. Follow-up was carried out three or more years after acute poisoning. Of the 235 individual.' 175 (74%) were located and 117 (50%) were examined. Of the 117 individuals examined, 114 .17 03122104