Document Z4vgyMJNEr5nkVnZ6BG0846Z7

oo FF MOErxagiyatni2in0zg0at0CihoenmifocralEscoTnaosmki}FcoCroceopMeereattiionng and Development rice AR286 - 0632 Re M0 Sep-6 py 5:57 PROS Assessment Approach in OECD quetonhs ereregcaerntdliynrguclheidcainfeocrhmnaotlioognyoannPdFhOeSpapnrdoiprsinastseos ciatetdodp aerkievativiegshtosfetshea duemsbseirnobfytihmpeomrtaajnot manufacture to phase ut production for mst ses during he current yer. CorpoAnreanatntdnistoihvnrsecotmopfasntiudeise.s Enfdfortths reeinufnodremrawtiaoynboentPeFeOnSUaSn EPtsAdaenridva3tMivteosdhissbiebeundtevhiesloipnfeodrbmyat3ioMn 10Membercountries,possibly via CD-ROM. A understanding fo co-ordinate forts leadintgo group of OECD preparation of Membrcountries havedevelopedan informal erecnin levels assessmenont PFOS and is ecovmbeinse,thisThweosrekcotuontprrieepsaprleanatoscdricvindiengrelsepveolnsasisbeislsmfeonrtvaorfiotuhse ahsupemcatns oafntdheeansvsiersosnmmeennttaalndhahzeanrds0, environmental fat, uses and exasures, and risk associated ith PFOS and is derivatives. This assessment would be used to inform countriesregarding the issues associated with the possible phasoefspoecuiftic uses and pertotveirduenadebrasstiasnfdoirngionfforhemedisjuuedsgewmheincths.mrsetgabredicnognscriidteircaeld uisneesxaolfuPaFtOinSg. suTbhsisiuweosrkwhciocuhldaaelsboeicnongtprribouptoesetdo ufsaorh, ethemOaEtCotDPRiSOecSvrasnetadriias dasebeienareftqourietshtevredeitsaaskseOsFaC)weMleambterhrcosuenst.ieTsoasnds,stihnrtohuigshcoI-FoCpSe,rantoinv-e Msoecmibaetredcodeurnivtaiteivsestoinpdriovviiddeuianlfocorumnattriioesn regraergidoinnsg.onSegvoeirnaglcprooducutionnh,aviremaplocrreta,sdaynndtutsesdoefffPorFtOsStocaonldleitts o"nfoportmenattiailosnnubPstEiOtuSteasndfsordespaetciivfeuss,es oCf PoOuSnaanndtdiirsnddueisriveatiisvlels.ls Idbeeallcy, hois wuoultdrpirnocvaliuddegifnfoorermmaattdiioonn rSeignacredeixnagmhiunmatainonanofdpoetnevnitroinamlesnutbasltihtauztaersdiss,ceurnrveinrtolnymaenntoanlgofiien,geexffpoorst,urseuschanidnfloeramsaetiso,nfsch.ooufldhbeleepmraoivviedsea.sd it becomes available. reviewedhnearetseunlttatoivfetlyhpcaanlnlaebdoriantfiovremaalsseexspsemretntmeaentdinhgeorignafnoirzmeadtiboyn obnienoefdthebcyoltlhaebSoercatroertsarpioasswiobullydinbea 1 September-20O00cttimaefbraemer. The goalofthsmeetingwillbeto preanpassaesrsmeentat a level similar to thatof a SIAR with additional interational exposure information mentioned above on PFOS and its derivatives. The assessment will include robust study summary level information on key studies (human and environmental hazards, pharmacokinetics, vironmental fate,biomonitorinegt,c),more extensive exposureand use information than is typicalof a SIAR under the refocused program (the information available from 3M provides afir degreeofdetail on ongoing prodiction and uses by that company, additional information willbe developed via the OECD request to Member countries and others; there is als relatively extensive information onbiomonitoringwith more information expected from 3M), and an intial screening level assesosfhmazearndts, exposures, and risks. The countries wil also attempt to develop inital information (and, where posible, Judgements) regarding the critical use of this classofchemicals, considerth issues associated with and gaps in understanding regarding proposed substitute, idenify needed steps, and develop proposals for continuing, necessary work. The results ofthis effort would be communicated tothe Joint Meeting in November 2000 to inform that body as to developments and to obtain guidance regarding additional activities as appropriate by OECD. "Theparties which have already indicated an interest in collaborating inthis assessment effort include the United States, the United Kingdomth,e European Commission, Canada, and Japan. The initial thinkingregarding division of labor for assessing existing information is as follows: health effects and pharmacokinetis of PFOS (US) and selected PFOS derivatives (Canada); environmental effects (UK, Canada): environmental fate and distribution (2); human biomonitoring (US); environmental (biomonitoring (Canada); exposure and uses (10 be co-ordinated through Secretariat). Japan will let the other collaborators know as soon as it decides on areas it can collaborate on. Other intOeECrDMeembsertcouentides areencouraged o indicate thir interest in contributing to this effort, Countries are also encouraged to consider initiating new (biomonitoring efforts o further characterize humanandenvironmental presence (deontthaeanialylticsal method devbey3lMaoreapvaielablde.) Consideration by individual countries and regionsof the issues presented by the possible phaseoutof PFOS and its derivatives should continue even as collaborative work is being initiated. 2