Document Z4EmgdXy50KLdEvN7nX0K8ag8

PLAINTIFF'S EXHIBIT ffovewb-er 20, 1936 LeRoy U. Gardner, V. D., Director, The Saranac Laboratory, Saranac Lxxe, New Yoric. '.Dear.Dr.\ 'Gardner : & u. k It a meeting yesterday attended by certain braxa lining manufacturers, lir. Slapaon and I were able to present to a fairly large group of Interested corporations the proposal that one of your dusting chambers be engaged far further experi mentation with asbestos dust. The proposal was very well received and it appears that not less thin eight, and perhaps tengn-aerrj--corpor-a-vians will participata in financing tliesefnmSer experiments along the lines discussed when we net wi-Ct: Dr. Lanxa and Dr. McConnell \ a few days ago." C _______ ______ Accordingly, you may consider this letter as an authorization to you to commence the contemplated experiments with asbestos dust for the purpose of deter mining more definitely the causes and effects of asbestosis. It is ay understanding that, among other questions which it Is anticipated these axperiaents will answer, are the following! (1) ^hat concentration of dust is necessary to produce the fibrosis of the lungs which is designated as asbestosis. (2) Whether exposure to asbestos dust will produce asbestosis without the existence of previous infection and whether the X-ray changes found in advanced human asbestosis can be reproduced in animals without Infection. (3) Whether the fibrosis produced by asbestos is of the progressive type, that is, will the fibrosis increase (once it has started) after exposure to the dust has ceased. 04037063 / 1/ ~ I *7 m -2- PUINTIFF'S EXHIBIT J0O5.C (l) Whether the fibrosis resulting from expo sure to asbestos dust Is occasioned by the silicon con tent of the asbestos or by Its fibrous structure. (5) Whether the presence of "asbestos bodies' has any diagnostic significance. It is also our understanding that these experiments will require approximately three years, which will mean that they lill not be concluded until about the end of the year 1939; and that they will cost <5,000 annually, or a total of $15,000. f It is our further understanding that the results obtained will be considered the property of those who are advanc ing the required funds, who will determine whether, to what extent and in what manner they shall be made public. In the event it is deemed,desirahle that the results be made public,.the manuscript .of your study will. be, submitted to us for approval:prior .to publica tion. I shall appreciate your advising me if the foregoing accurately expresses the proposition 70U had in mind. Also, let me know the ainner in which you would lilce to have the funds ad vanced to you. Would you, for example, desire to have $1250 paid quarterly in advance, or Just *hat arrangement would suit you best? Any method you suggest will be satisfactory. Since the experiments are being underwritten by s rela tively large group, it has been suggested tl:at, as a matter of con venience, any communications regarding the work be addressed to and I will, where necessary, communicate the contents thereof to Hr. Simpson and the other parties. You will be provided with funds by either Johns-iianville Corporation or Raybestos-Manbattan, Incor porated and we or tj.ey will secure from the other parties tr.eir pro rata contribution. I will advise you Later of the trlbuting parties. s of the other con- . I shall appreciate your informing me at the earliest possible moment whether the arrangement as outlined herein meets with your approval. Yo:T Sincerely yours, / I'L ^ Vandiver Brown General Attorney 04037064 J v >