Document Yrv0p2arD8EBV8ywMVjQ2v2ky

FILE NAME: Drywall Spackling Compounds (DWSC) DATE: 1975 Sept DOC#: DWSC038 DOCUMENT DESCRIPTION: Newspaper Article with Government Press Release f. .. snas have been ` .own {or both mri D m f y ' b." ` Although they h ive not yel pro duced ati r.nligen-.xmibody reaction for Duffy negative, the scientists believe there is tt substance there, and that 'stance provide* immunity against IX ix malaria. For e; am ple, vivax malaria does not n- exist in West A.frica, where 90 per cent :a, of the population is Duffy negative. re Most blacks in the United States also ey are resistant to vivax malaria, and 6S h e per cent arc D u ffy repalive. .-a (Because o f tliesc facts, tire scien tists were able ro transfer their la bora- : Z y . .j o i i * . -.H4 1 . .4 i . ' riK\*'. : i '. 1 . f ,. % 1 . V V ::; . i J J h\:., 1 1 i J --T '/ . *: - -v! Llf.fi f '-f.; :i .J_w.i --UJS. Medicina photos M ary MxGiuniss 7X ut 6/f '7 `Sr*- ^ rJL*tUf ? , fl W<*w ^t f -.***/>iFP**"**>e1''-' 5P'SK&rr'r9* h k` t i aUW -j> oi lasers, ranging from low-powered ones producing no harmful effect.; to those that could cause biological dam or age from reflected as well as direct ex od posure. Those which could produce damage must carry warning labeis. cd Lasers used for medical treatment of must, in addition, have a means o f o- measuring (he radiation intended to ir ,-d radiate the hitman body. -:.C F D A said most o f the required standards cither aheady arc in use or .as can be incorporated into existing prod *us ucts at little experre. Under the regulations, lasers must ..a e protective housing- 1risers also must have a system for ses indicating when they arc ready for use. ,S - ;p - *Ml.,,1'-. i-/ I*,hi|ilii ?' A 1;!.: :., ' , , t , J! , .......... , * ' : , v j ' 'i : '; ? ? ; : ' ' ! ;j:.;' :i . ` i!'-tl V i ' . i 'i - i . i ; ' '! --.O': ! t .r W *, j . ;*'' ' : ` ; ; ; M ; T : J ;.-;':. ` d I'' if. i * J * *\ <:1[ 1 ! . J;, . , tl` J. '.(J .ilt( il) 11 . ,., j '* K ! . ' f i ' 'i*'- ''* iyi':K d\U U 'liili{ ' iijiiii ...-v* i ' t ` |i - 'C ;}l; 4 . . . I <} Inverted microscope sequence fa!;eu ai N I H sliov's (lof! o right, Iro.r. top) in vasion o f red blood ceil by malaria parasite. After attachment hv U.x parasite (arrow) there is marked distortion o f ti.e cmi, iolio.ved by slow invasion. tory results using monkey malaria to vivax malaria.) Further, screening showed that all Caucasians tested were D u ffy posi tive. " This is highly suggestive that the double D u ffy negative is the del;uminant o f resistance," Dr. Miller said. This leads to tire possibility-- still in the future, however-- c f developing a neutralizing antibody tc tire D uffy positive antigen that would block in vasion by the malaria parasite. Su ch a preventive approach could offer new hope for populations unable to rid themselves o f the disease as the United States in effect has through medication and through environmen tal controls. For example, in West Africa, where falciparum malaria-- the ino.-t virulent o f the three common forms', vivax, falciparum and m ahriae-- is preval ent, nearly ICO per cent o f prc-schooi children' have the disease. Airo'her form o f malaria. Ovale,'exists only in West Africa. i f the genetic factor involved in these forms o f malaria could be found, a simple vaccine might be developed to stop the growth cycle. One merozoite. once it penetrates a cell in the laboratory, fer example, multiplies into 10 in 24 hours. c , h : ^ f * (ppcs R - ^ n r o g fc f^ iv F c s {TJ Va* S fc / l U iq U w Vu?- t. V j f '<a H.-?* x k.*-- Hh yr* 3'w 'V'S vZLl?i!**oe*?:iTl f** o'*?/'!." r-fc <*2* P H ?!Vjrf (13 R e se a r c h T r ia n g l e P a r k , N .C .-- A p - during home co__n__s_t_r__u_c__t_i_o_n_____a__n_d_____r_c__- preciable amounts o f chrysotile or pair," D r. David P . R ail, N i H S oi- other asbestos minerals were found in ~7ccior, saTcT ~ samples o f sparkling and patching --"TuISTtibnal work by the scientists compounds analyzed by grantees o f suggests that members o f the entire the National Institute o f Environmen household or other occupants of a tal Health Sciences. building may also inhale asbestos ft- The investigators tdso found sub tk-.rs. This could occur during mixing, stantial amounts o f quartz, talc, and sanding, or cleaning up o f debrs," i>e other minerals. sc id. Furthermore, air samples obtained D r. Rail said the investigators, all o f during the use o f asbestos-containing the M ount Sinai School o f Medicine, spackle compounds were analyzed and N ew Y ork , have accumulated oilier showed concentrations frequently in evidence indicating that far less ilian excess o f the cuirent . occupational the intense exposure o f the work en standard for permissible asbestos ex vironment is capable o f producing as posure levels. . bestos-related disease. Fiber counts measuied during mix The investigators analyzed 15 repre ing were found to be 7-12 limes greater sentative samples o f consumer 'pack- than the current occupational stand ling and patching compounds and 10 ard. Detectable fiber concentrations o f industrial rirywal! lacing com were found in adjacent rooms during pounds for asbestos mineral contents. mixing, and fibers were still sus Five o f the 15 consumer spackling. pended in the room air at least 15 min and patching samples contained ap- utes after mixing had ceased. picciab'e amounts o f chrysotile or " These f'tidings sourest th^ possibil other asbestos minerals, as did 9 ot u<>: ity of significant asbestos exposure J O industrial p r o d ^ jj ,,A / ' /, /? 75~ A- - .-V'arir 7) ,;/ ? (; - C ' c ? .. v c / ; / V PLAINTIFF'S EXHIBIT sp : U. S . DEPARTMENT O P HEALTH. EDUCATION. AND W ELFARE _ - - National In stitu tes o f Health : ~ Dr. David P. Rail FOR RELEASE IN A.M. PAPERS . _ O ffic e : (919) 549-8411. e x t. 3201 Analysis o f representative samples o f sp ack lin g, patching, and taping compounds by grantees o f HEW's National In s titu te o f Environmental Health Sciences* has shown th a t some contain asbestos minerals as well as other p o te n tia lly harmful su b sta n ce s._ Measurements suggest that home repair or construction work involving use o f such m aterials may re su lt in exposure to dust a t concentrations s u ffic ie n t to produce d ise a se .** Workers exposed to asbestos have been shown to face a g reatly increased risk o f developing lung cancer, mesothelioma (a rare form o f cancer), cancers o f the g astro in testin al t r a c t , and asbestosis (a scarring o f the lu n gs). These e ffe c ts generally do not show up u n til two or three--and sometimes even f o u r decades a fte r the f i r s t exposure to asbestos. R ecently, Drs. A .N . Rohl, A.M. Langer, I . J . S e lik o f f , and W .J. Nicholson a t Mount Sinai School o f Medicine analyzed 15 representative samples o f consumer spackling and patching compounds and 10 o f in d u strial drywall taping compounds fo r asbestos mineral content. These NIEHS grantees purchased four o f the : -- -=-- '.. 2 1 (more) *The National In s titu te o f Environmental Health Sciences (NIEHS) in Research Triangle Park, N .C ., i s a component o f the National In stitu te s o f H ealth, one o f the s ix agencies o f HEW's Public Health S erv ice. Additional support fo r th is work was provided by the Health Research Council o f the C ity o f New York. **D etai1s o f these findings by Drs. Rohl, Langer, S e lik o f f , and Nicholson are being published in the current issue o f SCIENCE. 2 ( ( packling and patching compounds at hardware stores in the New York C ity area in 1972 or e a r lie r , and the remainder in January 1974. Spackling and drywall taping compounds co n sist o f fin ely-grain ed white powder or premixed pastes. Although P iaster o f Paris is supposedly the major constituent, other light-colored materials including clay s, micas, quartz, ta lc , and ground limestone supplement or replace the p laster in many form ulations. A d d itio n a lly , ch ryso tile asbestos is added to some products, apparently because these minute fib e rs a c t as reinforcing agents. Analysis o f the 15 consumer spackling and patching samples has shown that fiv e contained appreciable amounts o f ch ryso tile or. other asbestos m inerals, as did 9 o f the 10 in d u strial products. Many contained substantial amounts o f quartz, t a l c , and other m inerals. Once embedded in the lu ngs, quartz or s i l i c a p a r tic le s --lik e those o f asbestos--may never be removed. They can produce chronic obstructive and fib r o t ic diseases a ft e r p'rolonged exposure. Talc also can produce pulmonary fib r o s is . i- A ir samples obtained during the use o f asbestos-containing spackle compounds were analyzed and showed concentrations frequently in excess o f the current occupational standard fo r permissible asbestos exposure le v e ls . Fiber counts measured during mixing fo r example were found to be 7-12 times greater than the current occupational standard. Detectable fib e r concentrations were found in adjacent rooms during m ixing, and fib e rs were s t i l l suspended in the room a ir a t le a s t 15 minutes a fte r mixing had ceased. These findings suggest the pos s i b i l it y o f s ig n ific a n t asbestos exposure during home construction and re p a ir. Additional work by the s c ie n tis ts suggests that members o f the en tire household or other occupants o f a building may also inhale asbestos fib e r s . This could occur during mixing, sanding, or cleaning up o f debris. ( ( These resu lts are a lam in g when considered in relation to other evidence being accumulated by the Mount Sinai group th at indicates that fa r less than the intense exposure o f the work environment is capable o f producing asbestos- related disease. X-ray examination o f 210 fam ily contacts who lived with the men who produced asbestos in su lation a t a Paterson, New Je rse y , plant from 1941 to 1954 has shown th at 40 percent have the kinds o f abnormalities in th e ir lungs common to asbestos workers. In some ca se s, the worker had been a t the Paterson plant fo r only a few days. Thus, i t appears lik e ly th at the use o f sp ackling, patching, and taping compounds containing appreciable le v e ls o f asbestos minerals in home repair work d a y expose the user and other members o f the household to concentrations o f asbestos th at may lead to d isease. nn.. IHHTW7W)I i V. +