Document YGv1Bd0oypeQRrv8qkJM0XVN
APPENDIX A
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Andersen, M.E., O.E. Thomas, M.L. Gorgas, R.A. Jones and L.J. Jenkins, Jr. 1980b. The significance of multiple detoxi fication pathways for reactive metabolites in the toxicity of 1,1-dichloroethylene. Toxicol. Appl. Pharmacol. 52:422-432.
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Chieco, Pasquale, et al., Effect of Administrative Vehicle on Oral 1,1-Dichloroethylene Toxicity, Toxicology and Applied Pharmacology, 57:146-155, 1981.
Cooper, P., The Varying Fate of Vinylidene Chloride, Fd. Cosmetic Toxicology, 18:435-436, ______ .
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Hong, C.B., J.M. Winston, L.P. Thornberg, C.C. Lee and J.S. Woods. 1981. Follow-up study on the carcinogenicity of vinyl chloride and vinylidene chloride in rats and mice: Tumor incidence and mortality subsequent to exposure. J. Toxicol. Environ. Health 7:909-924.
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Humiston, C.G., J.F. Quast, C.E. Wade, J. Ballard, J.E. Beyer
and R.W. Lisowe. 1978. Results of a two-year toxicity and oncogenicity study with vinylidene chloride incorporated in the drinking water of rats. Report of The Dow Chemical Company.
Jaeger, R. J., et al., Biochemical Effects of 1,1-
Dichloroethylene in Rats: Dissociation of Its Hepatotoxicity from a Lipoperoxidative Mechanism, Toxicology and Applied Pharmacology, 24:457-467, 1973.
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18 hour fast and glutathione depletion of 1,1-dichlorethyleneinduced hepatotoxicity and lethality in rats. Exp. Mol. Pathol. 20:187-198.
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Landau, E., and Manos N. 1976. Epidemiology Studies: Estimation of Population Residing Near Vinylidene Chloride Plants. U.S. Environmental Protection Agency 560/6-76-022.
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Lee, C.C., J.C. Bhandari, J.M. Winston, W.B. House, P.J. Peters, R.L. Dixon and J.S. Woods. 1977. Inhalation toxicity of vinyl chloride and vinylidene chloride. Environ. Health. Perspect. 21:25-32.
Lee, C.C., J.C. Bhandari, J.M. Winston, W.B. House, R.L. Dixon and J.S. Woods. 1978. Carcinogenicity of vinyl chloride and vinylidene chloride. J. Toxicol. Environ. Health 4(1):15--30.
Leibman, Kenneth C., et al., Metabolism of Halogenated Ethylenes, Environmental Health Perspectives, 21:91-97, 1977.
Liebler, D.C. and F.P. Guengerich. 1983. Olefin oxidation by cytochrome P-450: Evidence for group migration in catalytic intermediates formed with vinylidene chloride and trans-1phenyl-l-butene. Biochemistry 22:5482-5489.
Liebler, D.C., M.J. Meredith and F.P. Guengerich. 1984. Reactive metabolites of vinylidene chloride: Characterization of covalent adducts formed with proteins and glutathione in microsomes and isolated hepatocytes. Cancer Res., In Press.
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Maltoni, Cesare, Recent Findings on the Carcinogenicity of Chlorinated Olefins, Environmental Health Perspectives, 21:1-5, 1977.
McKenna, M. J., et al., Covalent Binding and Glutathione Depletion in Hepatic Tissue after Inhalation Exposure to [14C]Vinylidene Chloride, Abstracts: Seventeenth Annual Meeting, ____:257,
McKenna, M.J., P.G. Watanabe and P.J. Gehring. 1977. Pharmacokinetics of vinylidene chloride in the rat. Environ. Health. Perspect. 21:99-105.
McKenna, M.J., J.A. Zempel, E.O. Madrid, W.H. Braun, and P.J. Gehring. 1978. Metabolism and pharmacokinetic profile of vinylidene chloride in rats following oral administration. Toxicol. Appl. Pharmacol. 45:821-835.
McKenna, M.J., J.A. Zempel and P.J, Gehring. 1979. A compar ison of the pharmacokinetics of inhaled vinylidene chloride in rats and mice. Report of The Dow Chemical Company.
McKenna, M.J., J.F. Quast, H.O. Yakel, M.F. Balmer and L.W. Rampy. 1980. Vinylidene chloride: a chronic inhalation toxicity and oncogenicity study in rats. Report of The Dow Chemical Company.
McKenna, M.J., J.A. Zempel, E.O. Madrid and P.J. Gehring. 1978a. The pharmacokinetics of ^14C] vinylidene chloride in rats following inhalation exposure. Toxicol. Appl. Pharmacol. 45:599-610.
McKenna, Michael J., Letters to the Editor, Environmental Health Perspectives, 28:311-314, 1979.
Moore, Leon, 1,1-Dichloroethylene Inhibition of Liver Endoplasmic Reticulum Calcium Pump Function, Biochemical Pharmacology, 31:1463-1465, 1982.
Moore, Leon, Inhibition of Liver-Microsome Calcium Pump by In Vivo Administration of CC1, CHCI3, and 1,1-Dichloroethylene (Vinylidene Chioride), Biochemical Pharmacology, 29:2505-2511, 1980.
Murray, F. J., et al., Embryotoxicity and Fetotoxicity of Inhaled or Ingested Vinylidene Chloride in Rats and Rabbits, Toxicology and Applied Pharmacology, 49:189-202, 1979.
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Murray, K. D., et al., Teratology and Reproduction Studies of Vinylidene Chloride in Rats and Rabbits, Abstracts: Seventeen Annual Meeting, _____ :341,
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Quast, J. F., et al., Chronic Toxicity and Oncogenicity Study on Inhaled Vinjlidene Chloride in Rats, Fundamental and Applied Toxicology, 6:105-144, 1986.
Quast, J. F., et al., A Chronic Toxicity and Oncogenicity Study in Rats and Subchronic Toxicity Study in Dogs on Ingested Vinylidene Chloride, Fundamental and Applied Toxicology, 3:55-62, 1983.
Rampy, J.W., J.F. Quast, C.G. Humiston, M.F. Balmer and B.A. Schwetz. 1977. Interim results of two-year toxicological studies in rats of vinylidene chloride incorporated in the drinking water or administered by repeated inhalation. Environ. Health. Perspect. 21:33-43.
Ray, Prabhati, et al., 1,1-Dichloroethylene Inhibition of Liver Microsomal Calcium Pump in Vitro, Archives of Biochemistry and Biophysics, 218:26-30, 1982.
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Reichert, D., H.W. Werner and D. Henschler. 1978. Role of liver glutathione in 1,1-dichloroethylene metabolism and hepatotoxicity in intact rats and isolated perfused rat liver. Arch. Toxicol. 41:169-178.
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Gehring. 1980a. Effects of vinylidene chloride on DNA
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Szabo, Sandor, et al., Modification of 1,1-Dichloroethylene Hepatotoxicity By Hypothyroidism, Toxicology and Applied Pharmacology, 42:367-376, 1977.
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