Document Y9DogZZDGya9a7MNvvLKXB4jy

3M Specialty Materials 3M Center St. Paul, MN 55144-1000 651 733 1110 ( ^ 6/4776 Fil- Uox -oonys December 16, 2002 VIA FEDERAL EXPRESS Document Control Office (DCO) Office of Pollution Prevention and Toxics (OPPT) US Environmental Protection Agency EPA East, Room 6428 1201 Constitution Avenue, NW Washington, DC 20460 FYI-00-001378 FYI-00-00137B Attention: Docket No. AR-226 and the FYI Docket Dear Sir or Madam: This continues 3M's voluntary submissions of data on perfluorooctane sulfonates and related compounds, as part of our ongoing dialogue with EPA regarding fluorochemicals. Included in this submission are the following: "Biodegradation Study Report: Biodegradation Screen Study for Telomer Type Alcohol", Pace Analytical Services, Inc. Study Number CA085, 3M Sponsor Study Number E01-0684. "Comparative Analysis of Fluorochemicals in Eluman Serum Samples Collected by 3M and Obtained Commercially", 3M Environmental Laboratory Study Number E02-1053. "Analysis of Endogenous Fluorochemicals in Normal Pooled Human Serum and Plasma", 3M Environmental Laboratory Study Number E02-1039. "Analysis of Pooled Human Sera and Plasma and Monkey Sera for Fluorocarbons Using Exygen Method ExM-023-071", Exygen Research Study Number 023-082, 3M Sponsor Study. CONTAIN NO C 85030000001 85030000001 I OOOOOl Page 2 Document Control Office (DCO) The analytical method used for the respective analytical studies has been fully validated for PFOS in rat liver and plasma matrices down to 50 ppb. Limited cross validation for PFOS, PFOA and the other perfluorinated carboxylates in human sera and plasma down to 0.1 ppb was performed. Additional validation is recommended. We will continue to provide information as it becomes available. Please feel free to contact me if you have any questions. Very truly yours, Cc: Dr. Charles Auer Dr. Oscar Hernandez Michael A. Santoro Director of Environmental, Health Safety and Regulatory Affairs Specialty Materials Markets 3M Center, Building 236-1B-10 St. Paul, MN 55144 651-733-6374 (phone) 651-733-1958 (fax) E-mail: masantoro(immm.com 000002 JU