Document XzzpN2Van2r9QEBGVxZNM6doG

j M K M ' ' if J.^ic of |*ofv<*liIt*i**n(<*tl fliplH'nyls, ATc?l;iIs, umi C)l her Klcmcnf *; in Papers I'Vil In i! LncIntinK Cows A. KHlh Fwr, David R, MrHenn, Wnlln M, (Mitriimniin, Cnrl A. Hnrhr. nod Jhmnld .1. I .ink* i f.nrtnf in t mv* '`'ip frrl 9M% of rifher nrw-ipoper, Of li'mnr-'i. Milk |irr-ilm Iinn di-r lined VO :i:t*:t. d-ar. ;I |! hinwil or r.rry cnriUmnrd. or rnmputrr paper m n rrlhilf'-r . lr-1 iI*iIf- in their ration for periods up inj; llio paper frrdinj; rtpefinirnt hoi the animals wore endni)' I lieu InrlMwins nml wnrr |<rr,hMv to 3fl days. Polvrhintiivilpj hiphenvis (I'Clls) more eiu.r rpl (file to ration rhnnees />t r'li'> dev pir'.rnf perhaps ns ink dve carriers in lire* paper matter diy.e- .Uhditit-, were ',0.0, MO, 0,17. nod were f*r reled in milk up 1o level* of 70 ppb nitcl 77.51% for newi.pnpor, htnwn or fn-y r nidtnxud, timed in li".nrn nurh ns ttnnl fnl up lo levels of nml rnmputrr paper dirts. respectively. Cntre. I,'HO pph Dilfrrriilinl toil nhotinn nod ntornj:r of r|l*mditij; m film div matter digest diili lie* f"t I he rcrtniit of the l'(.'ll* weir indicated. Analyse' fur pnpiT r uoliuoinf: pellets were 00.2, 00.0, Ml 0. <7 mrlnl* nod olher rUtncnl* <1 id not imiimte fitxl 7S.I%. nlppficnnl transfer of thrso from the diet to milk Wo'lP paper 0ns Wen incorporated into farm onininl frrds ns n inruns of disposal nod to nerve ns n substitute fnnn of hIImImnp in Mir ilniry rnlion. Mrrlrns rf nt. (V.nit) uu unwonted up to 2U% newsprint in duds of Inctntioj! rows. (Ilfirt- paper tins lirrn fed to sheep (KislmnuIn rf (., )fifty). Mom* rrcrotly dirts motnioinr; up to 90% ! nrwr.pnper Imve hern rupnimrnlnlly fed lo cow* (S)irrrod 1 f.nd Hnn*n, 15*7.1). Severn! nth'-r invcr.ticntois Imvc also oiprriinrutrd with pnper ns n form niiutnd feed r.upplc* , Rirnl (Diinirln rf nf.. 1970; Thomas cl /., 1970; WHIiams fl nl., 1999; Milled rf ol., 1979; Hook nod Cninplinr?, 19.M); Kettle? rf at, 1907; pinius nml Olfjrn, 1971, 1972). In mmt of these experiments only rmp paper source wns used. In vilto .holies indicate that there ate lacf.p differrnrea in direstihilily hotwrrn pnprr types (Mrtfons el nl, )97M; Mrileos nod Von Smod, 1971) si>n;cs(inR tlint refrnfrli w*ll vsuniii pnprr Mirro is needed. In a irrrnl iimdvlicrd nurs'ey of pnprr* for the pcwsilde jirrseorn of tosie roostilorni.s nt'prrrinble conernlrntions of polyehlminnlrd biphenyl (l'( H) type rnmponnds nod vaiinns henvy mrtnla writ found in rrrtnin nnvspnprrs, riMtllmnrds, and computer pnprr (Serum rf p/, 1979). IMUU have nlso hern reported in pnper hnnrtl (Thotnn* nun Hrymmis, mr.l) nmi rniiionirss ropyinp, pnper (>\l.isvdn and l<ri|;nvn, 1972) which mnv hr mrluded in paper ptmhirls rrrvch-d info pnprtlionrd. I'Clts hnve idso trrrn repnitcd in n wide vonrfv of pnpr-r prodnris fry others (Hhnhird rf nl, 19/9; Xlnoovhk r( of . 15179; V'rmd Chrinirat N-. S, 1971). I he 1o*i ol,-ir sl(;idfirno< e of PCIU in the rmiiomoeot hns lrn* nmplv levievrrl (Penknll, !!/?; I'hlvnuh, 19(1'. I'nviummeotid llenlfh I'etvprrtivfs, )'.T.,,( I'rnknH nod l imn, 1P7( In the work rrportrd, p.s|>ers known l*v nmdwis to innlnio |*('Us (Arrrlors) nmi mi hds liave hern led to Imfolini; rows with Ridwripirnt nnolwis of milk nod t i-.-.m-n fm the- r foii< nof s. KXmttMI'.NIAI. SW'IIOM I'nllle Veidioft. Ktt.w..nii. rinllinaul. rtev caidtromd, noil ompuh^_irililCt__r'nnpry1rL_fmir lii;>rr (Ind ies o| pnpei^u'hirfr mnv rnntnin ITHs unit litee uir elM'M'U m, . li|v7 t fie nev\'.p:p|.r\<.u<L (tio Hultnlo V.vemiu: News ollei t d hrlw. ro |rcrmher. 1970. mill April, 197) hhtrli'.ri Ucolot f.:>).itoiv, Viri'ioin I'nlvlerbnir )re.|*. | nlr, Him I.- It.up, Vii|;iriin ;* |ci;| (A.K.)*.). Animnl Setroi e llep.ulHirtrt, |mvn Mate I Inivif v. Ames. |own J.llOtO (|) H h) I, nod IV-liridr Itr'olor l.nlmmlory, Drpmtnieol pf Srieme, New Vmk Stnle Cn1hi;r of Atpirulfme, Comrll ttoi\rilv. Illinrn, Nrw York HJl.M (Wilt!., r.A H .sndP.I f,). The lirmui rnidl.nnrd cr*xe i>.tcd of vnnuox n-.rd l.nri ml. Irelrd Inrnllv. The |;rny enrdbonrd mo-uled <( rofU of I'.fry pnperhniird (lh>t;us 1'oprr, 1'(`1*' 1`nprr (*o , Itm In-trr, N Y.). VJ'ied computer pnper was olitrimed from the f,,f. nHI Universilv Dairy Records Profession I .nlimnlmv. Ahout (Ifto l(> of em h pnper wns nroond in n hnomier mill. Tltr pulveri/.ed mnlerinl ws mited with olhn (crt fdostitorols so ns to comprise n complete linin' rnfioo The level'of 90% pnper in the pellets wns .rleclnf in n| tain a rumimnm intnke of pnprr nod PflH roulno'innlion T)te feed composition is shown in Tnldr I I he fml *on slitueuta were thornncblv toned nml I hrts pir-ed mlo 1,27-rm pellets. I'our cows (three I |nt<il-ms nod one Ayr shire) were each fed pellets rn>Uiomf. one of Mitm- |>o )>rrs. 'Hie pellets were frrl (hrmifhoid piriorls up to .IP days lici;itmtii|; with nn ft dnv ronitilinninn penl. IIimimi; Dm rni.tiiHinmij porio't tt*c ooniH dnd >'.....< i,,,,. nod prnin were progressively rertore*! while the <pimilitv of pellets wns inerenserl It wns nreessnrv to cooimoe ferrlmt; I ,H-7 7.R kp of liny nod (I 'M I ft? k,: of ,;tnio d.idv nir-f the rtriolitioninjr period in order thnl the rows woobl ,i, rrpl the pnprr-rnnlnnmip pellels. Moimiiic nml evrioor samples of (hr tolnl mired milk weir token prim lo (< < d lOft paper t<cmtui:t nod dsitv thuwiyomit the tn-dmi; pmi nd. Ihr morning nod eveomp milk samples were fmu hioril mill rfny prior to non lysis h'ri rs wns c nlh r I, d mi: sper inllv rlrsi|pted fpitler itnys nml om-p wns ,.Ifr * tr-rI mo crtthrtri for 7 dnvs nl the end of emit frodmi; peuo.l ) >rv lonttef nod Kiildnhl nitro/eo noth...... win- pmlmioed hv slimhird mell>nd<i. fell e.jill deter muml nun on.I itt iiltti flir.e't lhilit e\ of the paper i not iinioi; prtfel'i we,,- Alter mined Ity the ptm rdmi ", of (i,.ei,,|i .....I \'<n, i ( l`i,ui Al I lie end of the ferdilli; pr-rioif the ooi>o'il< mie on fin tl nnrl fissile samples taken (or niudv <" I aide H h t- prrlimiil dnl.i iooii< mni; the fi.-ium ImmI I lie told m take of I'CHs hv ent h tow <v:i*i ;i I f I ;i 11-I tnor, (lie lilies of the pirlirohu paper imd elfidt i i on-iioi-d .uid (hr- < omcol ml ioi-i of |'t M'i |o.,,,.{ iml.ollv in Ho e I. . .| eonipnoenlf ee 'I'nltle III) Methods of Annhsis. The no-ds- i' fot I'Cll-. x-n-i il. .n. iv-iur. the puhlv heil mi tle-d tl'c.ln ote Amilvtii) Muoonl. 15*711 involvio|. fnt ilr,uluoi, >.,<|nlioo uior m elmoh de pmtitirmioi:. 'ind roll...... i litMotitloernphv mi flon<d l*'eies imopb"; ^ere piore-'ted nsutc prori'ihiie ft l.t in I lie nlimr nfi'ieiire luod deletmuctmo wn*: perfoitoeil hy rteefroii /dliuilv r,n% i hiomnlopinphv o" pievnoedv ip polled (Srimo ,( nl , 197,1) ereepl th.il llie fro; (luoooilo ipnptiic rolioon roolnioed r-% ()V 17 m* MM |MM roe-h ( !llrnoi,H.ii<|i AW nor) n n'. fi ft lone (pin o 1,1 nl ,oi .. *r>nde ly men' oriof the I1 t of Hie ihr--e p-el * m- # fS i aor rnrHClism . Vat 77. MmA tSfl MQNS 086349 t I' ll rl > i y.Ufiv, llcrriv.rv nl I'CM. limn Bami-ln. ' Simple Added, ppm Me- EeltniMrd fnvcrjr, SCnsUlvlly, % PI* r>s Milk Urine Trrel Drain * IIpiiH Kldnfjr Idrer rplren Iirtnkel fat Omrnlll ltd llrn*l fat Cl'-wrli Mound Crmind alfalfa Corn mrnl (iiiyhrin mrnl Sodium chloride MononuMum phonphnln Molaaaee o.ot 0.1 0.2 0.2 0.2 03 0.2 0.3 0.2 0.3 . 0.2 0.3 0.2 0.3 0.2 Mi 0.0 l.f>8 0.0 1.00 0.2 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.2 ns 77 04 ' 103 , 38 57 08 57 no 09 06 05 07 . 77 07 03 00 03 ' 08 04 ' ' 73 72 Gt 67 75, 101 ei 70 75 09 93 1 10 14 5 5 S 5 5 5 5 5 .1 1 5 3 5 5 5 3 5 5 5 5 0 5 64 4 2 o r* io' ir ''3o A` no days Flflwe J. Giflfl* showing tt,0 rnnrrmltnllnm nl I'CMi (pi-ul-. pm nIH*on. Ircr-h wnlpht) In nulk n* n fvnr.ilpn of Inntjlh nt Him* nl (OOtflnn hK'wn f ntUbonrd In tl*n rtnlry fnllnn * r 30 20 10 i--i--ib--i!r .ifr~ &* -l> DAYS Rgui J, Gmoh j.Ik>iviiici llm t.tinipnliiitlnn* i I'C-ll* (unK < million. Iiof.h wnlpAt) in milk in a (unction nl longili ol limn til fording grey crndbonid In (Imi dnliy tnliun d fi 0S lb "lb 20 ?5 jb" DAYS flqiHt 1- OiAnh Owmlng ((* rnnnnnlrnl>on" ol PCn*. (pn<l'i pv million, f*.* wl<|i|| m rniik n* n (unction ol ImiQlh ol limn cil fpoilinn npwM'Apn In lln dnliy inUnn. rirjmn 4. Oidjili slinwlrit) Ihn r nm rn|r nl 1*1 M [nnili p'i iryllkitl, Imi' Ii V'rigM) In unlit ;r. n linn linn i.l ll. nl (lion <1 fpnillntl rnitipiilM pnppr l>t llir H.iuy i nlinn ink, tir'|in(. pln-dir Imp*, noil pt*-lir prodnHi II ktimiM fir nnfi-d lh.il llm rnlr* of hv wir mniinf.ir- lirt |Mum*f *n ) in inOy linvr 1*<-rn ir*.l, led In ill M-nlnl MiimM TIu-m nr in ink* mnv thMrfnti* <ln liiir f|fnt'>|Tti"lil lltiiur nl iiiilnttf >i tni-il on f;duii< ivliirli mnv ' ami v i vf iri \ I mi* Inn V i nln Ml nm I \ |>ir''l j'i | *<-1 4II* r.;i llir hpinp |>"|.. f Imi n v:.7, nip innlrnll nir MiU'llirr pn'i ||1>- Mi.ifi ii| mill..... . S|nMiiMiv j-n*. f |iMilunl(i|'Mi|ill jc prnl< linve |mi limn nl.-mvi-d in crnirn -Iniril in rlnlli Imp* (1/-* find Nimuki. 1'IT/J, 'I'ltfv nmv nl-n nrnii in ||,rriuilinr* ii'i-il m dm (Skimtlny rl nl. 1*1711. Tim innvrtir* pud t-.liinnlfij snntil ivil ir nf (lie nulli ml for IVM* nr iJimcn in TnMr IV. Tlr rrcidurf* of I*< Me found in milk n* n funrtinn of lltr Implhe of lime of |o( *c illmlnlnt in ripiiic, I 4, Thr I'CM mm-fnlrntnm ,lliml fnf <li>V ?MI> t ><l fl'r|'"l''ll-1 11* lli>- )il rl.-. . | i. |- t --i.l M-l levi-l Ki-plii nlr lunilv'i-'. mmi- m-i.l. n| ii iIimm nnpl. lllu- 71- mill .!* ilnv milk ;mi!*. m I ii-nn- .1) I In i ml rulintri nl mi-i inmid m llm mi...,,.. I, ,, ni'l.i nil' 1i- 11 11 in 'I nlili- V 1 III' t mu inlriilimm nl I I I! . uuMi mill f i-.-.in--t n-i '.lunvu in I ipmi I I mul in tnMi- V w-tf iinl i nun I r-i| Ini pm t Mil in nvi i v 'I In* iiu in Hu- , nli if mu l |*f l< ' in llu* unlli nf llir ihiiumI Ir-il ui iv p.iprr mul Ihim, ii un*l pi.v i .nt Ii.'ImIi n't (ilinp |i<M|-rr" rrl i-, i-vntciil til li|-i||i-i I .1 |t,i<.n| iiu llu* lrvr-1 nl I'ril inlnkr 11 - ...iv If rl i-i.v i,.nl lin-Kil c j.f. Ir.lly Imi'Ii.'I llir Im.-Ii.'-I I'f II h-iiiimIi-i tiniri wrir nl-n fniiml m ||u (nl 'ninplf-. n| II,n mu ( luld- V). I'lir (iniill.ll It-il tnilipnlrr |>n|iM tin un<<- *> k mi.l Vt'lnpnl flinuliM, nlii, ti mnlni'u.l I Ii,..mcIi-'-i* '(-* *i J Api .......IChnni.Vnt ?. No 0. |Of4 MOMS 086350 1 j Tnl.le I. l-'red 1 ConMIlucnf W(, % rijwr Ground Alfalfa Corn nmal Soybean meal Rndlum rhlnrldr Mnnnondluru phor.phale Mnl.iisnen 30 30 30 3 1 1 5 |nr M rrfrnlintt lime. of HD 4, 14 .1. nnd 44 ft mm which fOlirfpmulrd Jo Mime in gns chrninnlfinTAiiis of Ami lor 17.M, The method of isnlnlinn nod drlrrininAli.m i*ko per 1mitted rmnlysis of Ann lor I24Z whirl* inny lie cmumnnly prren1 in wn'-tc pnper. Annlv'.is lor 44 element* (A1, Ar, A*. An. Du. Mr, Cn, O, Cl. Go, Cr. Cn. Gu, Kn. K. Kc. Ilf. I. In. K. I,n, I,.., M|!. Mo. Nn. Nl. Ni. III*. Ho. S, S*. Sr. Sr. Rm. So. Sr. Tn, Till Ti. U, V, \V, V. nor! Zn) wns performed using Mcmdrnlnictivr rindf'-' ?:Mvnt*on nnnlvis. Milk `nmoles wete hWndrd pnd (e-nr '-ample* wrtr ipmmd nnd mixed. Tlir samples wrir dried nod l r ol r-nrh was siilisnmpled (Mill weighed Inin n pnlyrlItylrnc viol {I..* cm i,d X V. cm high). `lire Romples were irrndinlrd I wire, oner for n *1uh( pnind (which vnrird depending on sodium nnd < Itlorinc rnnlrnt Iml on Mm ortlrr of I min) nnd ngnm for n period of npprmimntrly 4 hr. The nrnlron flux lo which Mir inm. (dm weir cipnsed wns nlmul 10n nentrons/cm* per see (1.2 X |0'* for Mir nhnrt irrnrlintion nod I 1 X (O'* for Ihc lone irr/uliidionl. After (lie slmri irmtlintions (hr Rumples were conntrd within n few minutes on n Gc(Li) counting tytfrm for a period of ft min. Dnln were Acquired using n mirlrnr dn(n No. 4(20 miiKichnimcl nonlyrrr ntul stored on mnrnrlie (ope for Inlrr processing. For Uic long irrndinMnn*. (hr sAinptcs were counted ns soon ns prncMcnl. ronsideriof the level of the Activity doe to sodium, This prt(ol of lime vnrird from 2 to 6 dnys nftcr (he eml of the mAtlinlhm. After nrquisitinn, (he dnta were processed using no HIM 370 computer nnd n developed pingrmn. The main func tion of tiiit* pmgtnm is to find the nrrns mulct preselected pent* in (hr y spedrn. The program fit* the penks In n mollified RoUMsimi dislrihution, Assuming n smnll n'vm- melry for (he peaks, on n background represented hv n ipindioln 11*. program is cflpnblr of ol*. trnrtinr inlerferrnre due to peak* close lo Ihc pe/*k of in- To hie III. ( <io rol r.itiou >if I't |i toil i nil i (`fell < `on*|irnen1 S.itii|*le rch-i, (ph New.spa|KT Drown ranllm.ird Grey (Mrdlmuid (!oinjr.|(er paper Ground alfalfa (a*rrt meal Soylieaii meal Sodium chloride Monn'tndiutn ptiospli.ile Molarr.en 120 17 r. io .170 ft < Ti ir> <i "i *2 lrres(. Hie rumpulntinu nf ports per million whs lm.d'.n rnmpini-nii of the penk nmn determined n- nlmve wiM penk nrcft'i determined for sl/inHaid'i run nmli-r knot* n i if cnuvitnnces. The di'tiiininiilion of e.idmiiim nnd lead wn-i p>-l......... hv dry nslung .r* g of Mir '.nmpli-i (up (o 47!*') |*v Mie i>Sprelive AUAC iprMind'! (IfKV-) followed 1v *i*'d\-i" lemr ronvetil innnl flame ntoniie ole rupt ion S|ier1 lophoimm Irv with (i J'eikin Mnier Moil--) .'KM tiv.l ninirnl, I ),e .l.liinii lint inn of inrrcu'y wns net oruplished hy oxvnrn (t.e k nun hnstion ((iolenrnntir* nnd hiU. IPfiO( of t f snrnr<li<t ilrv wriidil) nml flnnieless nh.mir nlicnrplion nnntvrei tllnith oml Oil. JPOfl). itr.stn;rs and discussion The concrntrntioos t>( I'CMs in the feed rnmpnm nl" -nr listed in Tnldc III. Pnper wns the mnin rmthImiI.r o. I *(' MShlMie^fUMl^thH s-n7T^rHrTTTor7t^m^TMmrp^7!MI cnrdlmnrrlr, nrc in/iiie from irrvi led puprr. I`t `M* u me ftr inslAiire, ns dvr curriers in Mir ink nppnrrjiilv 'u"'-1 Mir i nh Trjunvnl r"'l rrrrpprni;,,p miirMt Im roni i.inm ilr (lie cftul('r( joedurlr.. Ink lived f*rp*in on me enri fllU* Kinlnlmte lo Mm ITU f'm'rn*. nr.unllv pcrpnrrrl from viiein wood eellulo.r nw.lr t. d" nod dors not rontnin fervt letl < toul H nc-nls Ink >e - d i-n i>, however, inny npnin c<mlnin l`( The jm-".rm r >f l rm of ITIln in oilier of (In- feed rmitlilnntik mnv In iIik- In the idiirpntoilK pMSenrr of these roniponruli. A*- pmnhd out l*y 1`iire rf nl (1972) ITM'i luivr hem identified in n rnnee of snmples inrhuling Rediments, river ivnter 'enure, TnMe If, Dntn llelevnnt to the Feeding Trlnl l',1|l'T Newnp iprr Mr on n tai dtoiard r.r**v r rsril - lunril Ouopuler p.ifire Callle hr-eed Itrdr.teln tlnhdeln Ayrshire llolsleln Wl of row. hr fiR?. 105 Tnl.il peHets* rin;iiimri| during hint, Mi ToMl Mil Intake, mr./M: lusty w'l nt fiVO o.nu 0.0(5 500 lift 0.151 512 3.11 0.001 hum (inn of 01(11111'. days I'til ;>l ntIlk pi ( rlured dm trig a ilmll.ir Total milk pel !( 1 iitiiu ill produced dm Inp airly P.t".e .................. Ill luMI- (rial, kp trial. Up pi 1*1)0 1 Il 30 790 111 ftVA mi no l'll ? 21 37 nr7 975 it r, 10 527 790 11.3 MONS 086351 TaWcV, Hr shine* *( I'CM-in Cattle Tissues nml Kxrri'ln ) TlAtwir Pen ennen (ppl* Irrtsh wt) In cow fed Hewnps|er Itruwn ftarcthnnrd Grey card- board Com* isifcr |).iprr Hrttln Heart Kblff7 iJver fipfecn llrlhket fM Omenlal (al llciial fat Clmck lUnirid Urine* Fcccw* , 22 to .1.1 fi. 7 111) m 111 17 7 <10 <14 0.0 0.7 12.7 in.3 5.0 10.0 77.3 70.0 16. a 25.7 < 10 <14 at ni no 210 <1.5 120 Id no into - tn 20 <10 29.0 i.n 25 17 5.1 5. 4 07 00 no 11 5.5 <10 <14 j * lliim f.v.*; *!b-tH *'** U*( <|*y milk wo* r.m|>ltd. 5, (,Iihm,>1hh< mns tal (Inpl mHV ..imples on the (1/IM rf.iy >< tl.e row leaf prey t .Mfltmaul: pmrWI*| u"`Y e.*t- pon-H ntul .ii<| Aim hit '.noalaiaf* 1?-*? (.f-r'ieal lio-t .'< mrnl. 'Pip nh.ntir *( elevated "iirrnl rnl imn nf f'Clb. in fit'* milk nml loll v mif:lit appeal In trtlrrl lh-i d> mini'liril nlv-mplinn nmne t'* a shorter n-irfrme time nf f*s| rn*h rial* in On* r."l. This mnv fimir the me ismrd in I'ii'n difestiliility nf computer paper In !>r somewhat lower I>nh man*"! A nannha-t nf mdisarnplr* nl rath nf the j-, m<d p,( i* n i ip taken nml Ihnmitf llv nmrrf pu* In imiiK- iin In ii'inimi/p On* pm nltpil v O.nl n l.ia'r.l .......ph- nl paper was inmlv/i'il I Ini'i TItr vnhu u h-r. >1 in I ..l.l- III for Oir initial rum rnlfnlmm nl I'O.O'i in Uip |ni|"'ii fi t nre Itelieved In he reprer.r ntalive nml vnta.l Ir/pire 5 i.lnnv. fliminfilrij imnn of liar nulk sampl'd mi I he Im* dav ('Will ilnv) (ruin Hip iihv fed prrv ranlhnaid flop il)n>>iit<i,iom), fnv rnidhnard (middle ilanmiatn. pi.-nnl, mid An..has I/1 ; (111v;)*p11 line) nml I2M (bottom F >i(/(tnl>7;inin) ') lip rniii" (iMiiilnif; jh.iIi iilrnliun linn * in Oip (liinnmlc|Mmn* ate ividrnl Mf | f l,r* peaks in I)ip fliriMiuildcrnm1) nl Aieelms 1712 nml I'.'M nl*.n nppi nr in the i hinmainprarus nf f.trv rnrdhnard. Certain p.-sks nrtrb n*. Oner' of Arorlnr 1712 nml nnlnMv lime in the l hnminlnj'inm nf prev ran I hoard Unvini; ret* nl i<*n limes nl IO.fi. 1.1, mnl 'fi r, mm were /,!>., nf in (In* .. ............ pi.im nf milk ('nnsi.lrnllv, rrilaiti pink' mill m lli** p rinrt/;i)<i: n| l.* nml min * )ic.|..n I ininiU v smaller in tin* milk rtm>ninlc|;rnin I Unit l|p i 'irir |>nn*l- i*VJ |>r*k* in Ilif* i;irv rir<JJn.nirJ rJirmnnlnrmm, Oimi imliriiliitq Inrk of nli!'i|>tinn nr pni'iililr im Inle.li-m nflir nit. Ampljon. `I |r .` /Jinr rj'i i limn nf r1>t'mirln|;i njilnr penli*, willl (lip spci ific ones nienlmnrd ftlmvr inlmnl in i(p, fll.'f) Apjirflilli in Im- Jii.itniln;:.';'r>'. nl Ivmic* U Oip ( n-v fed r.iev ffiirl'inAld. I'.in li <( llit n(| f t Ivpr* Im-ivx. poper, blown ntdlinnrd, nml nmipuli r pnpril )r><) prot* cnM<-*pnmUnc lo Amrlor )?\7 on well n* l/M I Ip nnlV nml lA'.r* limn Ibr.'ir r.nw* nl*n r.lmwrd nppin<imn< ly llp imiir ftprrlnun of peaks, i.r mainly lbo*.r of Ai*lr J2T0 Ald only small nl nrclijplilp levels nf Om'-e m A:ilnr 12-12. 'Ilio name peaks (bat appeared smaller in milk nml tissues of the cow fed j;icy cttrdbnnid n^ain wnr n-*lm(d in ftir.c in Ibc milk and lissups erf Oir oilier row* llm would Iheieforp further indirnle rliffprenlial ahomplinn *ir nietaholism of errlaiit of the mniponeids of Aim lor l.'M and 1212. Il should be noted, however. I list Ihe rlerlmn affinity deleclor rrs(*op*:r nf Amrlor 1?(2 is imlv nl*>**d one Ihird that of Arm'lor l?M. The ah-rnre or near ah. seiife of Arorlnr 1212 may n! least in pail therefore have hern due to a lack of dHertor sensitivity Differential metftholiMn (Omni rl of. 11*71) ruul atninre (Cnihv rl nl . JD7J; rf I'{*!' *o rats has ob-o been indu ntnl. 'Hie mu* lion And peisv-tenre of I't 'lt* in mwi milk, its Hmnje in tissues (Fries rf n/,, ld'12, l!*7.t; 1`latnnmv >1 nl . t't/l; f*aa cheulirei Iter el of, t'W7) anti it* f irue-pl u entol lniif"i m the l*ovjiie fl'lidnitow am! (ihen. have been stmla-d I^IC le^inn nf Wilts in Ihp mine "ml frre<. was tnium m i*n rbrlahle (Tahir IV) hnl v-nme elimination of n ib -rr ohserved in lltr urine anil feres of pter.dnb...... . rnb. H'lirer/fl/. 1M72). Apparent diurnlihditv r neffii ierda. the rnn-mmed input mirun fbe fn,i| milpul divided hv th* mi >nm >1 inp**l. were rletorininerl fnr diy matter, ri ll wall, .ind i null p*n Irill. Sum p f liere was mil v mop imimnl p*-i I ***! m* nl. mi im lilm tei liniiplr war al-.n ir id dl * iml"C d< V tmil 11 * nml rrlf v)l di|:*'\tibiljtv *>f the paper rmit 'iiniiii1 pi lb-ta I In- rhimii at tmipo'-iti<m ami dip.* trlnlilii nl tin- p ip' t (*>n faif'ini; and tatioii. are rivim in I abb* VI nml \ II Table VI )...... that tin- addition *'l (be *-maH 0..0.1..I nf Jt.'M* anil ('i.iiii tn ))>* paper root iin*ii|- p< 11*1 ; <l-l not < mliiilllllv iliimpe the * la mu id 1 mopo .it ion I - f'll til* <napb-lf' 1.limit nml Ihr | *-)) I - Tin- ......... .. I*** *'>' 1 D".' pl llels iviie. lin- moomil nl It.r lolitl > 11 >i villa I hr </.-. (Cii.i.mmi: ? .1. * '), *'. am) .' O'- trf lb... l--v .v< l.l I<iiIv - p< ltd-.. lin /l., liladtlb-s rp.en m I i)>h VII , oi.Imoi the v-,,,a I inn in ihf- libddv .-noonr rliMi <* ol tvj'i . ol pipr !* MW.I In- Mr dens ,.nd V.-m -f (l'1/l) J he ,, ff.nd>V Ui.atli-r all;* ' t al ail it u-. ii|M r with llio e i>f Mi (t> o ranat V-.ai S's'-f (|U/I| in that minj'ilh'f paper ami nml ilir' r !<- fnllmvrrl hv Inown r nrdb"`>td, ftey 1 iinlbnsrrl. ami n*a- paper. Ifn-va vaf. Ihf* trt imil lllfi - I lluhl 11 1 H* t.......... nn*l ipev r.irdhoard'. ware muih |ava-f than Iho pudor el hv the ni I'ltlil rail l|ll^lmt f'r.rl. o. -I.* - *'.. MOMS 086352 U)K " < Tttde VI. Chemical (*nrnp"itinn of I*n|rr*C'n<fttnlOf! IV Hot m nml the ('nmpbte It at inns IVI In (lip < otvi Li................. ...... ............. - llruwn cardboard - ivifrfo ItAlfon Orniader paper IVItelA U.ifton Newspaper IVttetn it.iltmi firay cardboard VrlU-in Hatton ` # Cnulc protein, X , , Cell wall, % . . Olhtlntte, % (lignin, X 11.ft di.n 21), C 0.3 ... fZ.fJ 43.7 27.4 7.9 (7.9 4V7 ?.D. 5 5. r l.l-O 43.7 2r..& 5.3 f.t.n 41.0 23.n 7.7 1.7. ft 40.7 22.9 fl.D 11.4 30. f. 31.0 0. 1 12.4 4n,o 2fl. 5 n.4 Table VI1. fn Wlro* nnd in Vino k ItigealMilUlles af the I'nper -('ontnininr* I'ellets and tbe Complete It ntiona FpdlothoC/Ow* ,, , Drown . Compiler ' Gray r.ardlrnnrd, % paper/ % New-. paierf % mrdboArd, % J'ellel HuHon relict nMlrm relict Ration Pellet Ration ` )3ry m;dlc.t' ea c. ot.c. 75.1 77.0 GO.2 59.0 59.5 52.7 Cell wall 50.0 2C.. 0 70.0 73.1 30. n 31.2 10.7 72.4 Protein 47.1 72.7 04.4 49.3 I'llbt Hir.r'lil<i>i1ic* w<rc ilrleiminrd iin infcn. * Ration dlscslibilllie* were (Iclrimtued in vine. ' Tire aniinnl frit ronipulr, papp, irk Hmlnji llr (m-l 2 day* of (be digentinn trial. Hr" for tHrw* two rntinna were also lower than expected. ITir protein dlgeislibililira of oil four rations should have been rimilnr because the r.atnc protein Mnircca were used to supplement each diet. Mnr.it there was only one nnimAl ptr treatment. it i" probable thnl the difference" between in I'li'n and m m'fro digcsfihilitic* could be attributed to Animal variation. Tbe rrrwlta of nnnlyri* tf (be paper* fed, milk {"rtrnplcd on Ilift laM day of feeding paper to each row), liver, kid ney, mol miracle (round) (tnken At llio time of r>faugMrr| lor tittiln mol other Momenta by neutron activation nod "(molt r.nfdvris are hMed in Tables VJU nod IX (r.er paragraph at end ot paper regarding htippli inertia* ry malninl). 1 here was no correlation between tbe con* rentrAlinn of pnrlifnlnr clnnrntA in the varirmn paper* Oixt their levela in lire respective tisauen or milk samples. Aa would Ire expected, certain element* m< h a* lead nmJ cadmium troded tn tie higher in liver and kidney tissue ffian in inur.rfe er nil*' *ee (hose organs Are known In concentrate heavy metal*. Considering tone elrmenlft, a high concentration of lead (flO pml (mntil in newspaper mny hnve derived Inffelv (torn the inks used in the eulmrd pages. Itnnkin rf of. UDl'l) Mpmtril a range from ft jipm of lead in Mark ami while page* to IMkXt ppm in colored pngra. Tbe inks fArtged from '/>!> ppm ol lend in black ink to 2tV*X> ppm in yellow Ink Onlv a -mll (less iban (bOPS.) proportion of ((-ltd fed as lead iithnlfi to nm*r was found to be excreted In milk (Slnoiry ct of , 1971). The rnnccrilrntinict of h -u| in the Oiifk (7 i f .7 R'i ppm) aoi| tissue snmfdrs ? Ii ppm) are in about tbe winr range as lluve npmlrd ni l^mnl (nr lend in dmiv pimpicls amt nieufn INchmedi-i , ( l., 11It11). 'I be tom rulratums of bniimn found in Hu- v.iri- run milk III 7 H ppml and Hvur <0(11-71 I ppm) samples Appemi'l high and of imteetn, These emu enlint inm;. h**w. HTt. Me in the am** range as those touml in liumnn ternr-s <Sr I'WII) Itarium ndmini' lered tubi ur.t iwsoedv a* liiiiim 1ilmid< In t'.uinra pur* was 'lm ii to anumutafe in tbe f.dbuiinp Ii'mi in drfiri-.m,. m>|< r Unix, nooih', bone maioov, (bpestive tr/ul, bmps, kul nevs (1'ndiant ami Heimd, I'WliM. Ibioiets rt al framd ivi a<rmnulntion of minerida by beef liver in cattle , Ini newspaper. In Mimmarv, rattle ennaurninc a diet routaimnn 1tt`,f fin rirbll paper ru n trd up In 7R ppb f Pf-Hs <io cm>v rw*'s.*nl> in tlie nulV. Itc'idnes of i't'lts In milk Appear In increase asviuplntically after aevera* .lavs cf tievoitoiiip paper (see I'icmes 1-3). Hrsirlues of ITUs in ti'.'ocs at laiued tlieir bii'bc't Irvil (IMU ppb) in rrnat (nl o( llie row fed j.'rry ratrltmanl. 'l^iejuesrnMoleyyj^^jtJ^ili in fat iin.sis, b'nl suluhle"comiiminds kucIi ns iRf^iohrldfui rnteiMerplienyl* can fontaminate cciinin nn^rr modmls (ViJIrmAIIWt H r>wi moy hr pofrntiAl rmilnou- nants nf animal produrta (I'lies find Marrow. |'.t7.'H. ITIW arvf related compound* are now no burger perutl/-/f for use in naper modoefa. ~ Certain I'tlft"jKomm^ftm^enred fo show differential nfi- rr>iilmn^ucTaTioMSiii^^ni^SS1>^_:.ti,riMV^T*m)l animation of unlit and tissues by imic elements in paper pn-im.'. did rml appear to be nigmfirnnl. hi iu-a ihy mailer <li- gC'-libilitirs were fn.W, M fi, J7.7, ami 77.P% for nnvpa per, brown ru grey rardbnnril, and toinpiilrr pap'-i dvi-i, irspeclively. ('nrre'ipnmling in rihn div matter dipp'ifilnbtics for the paper rontniniog pellets were t'.U 7, Wlt.'l S, nrul Vb.l'Si. The dccreree (?0.2 .1.1 in milk pf'-iIlK lii'O found (see Tnblr H) in Ibis experiment was also noted in tbe work of Meifeii* rt nl ft?t/ln.M. The nnioiats were ending lU'ir lari at ions ami wrie pmbnblv more aurrpt ilili In in (inn changes. ACKNinvi.t.liCMKNr Tlir autlmrs ttiank (' Iv Cnppock lor f a(li' l< iiMO|' and It. <;, Win lie t Mill P. I. Van ''.OX'I l..i i..|m, r dmior t Ur experiment. I tn v are indebted to tin* Anooal Si lem r ( p iilimnl for :e i .lame in milkinc ami no.or l..i ll.i om ni.-d'i, to.) M King Inf :uti(iring Itwm noil l. i.i .i pling, ntv\ to N (' Ib.irlv (or limmi ml < i lime Supplement irv Material ArndiMe, I'abli : VIM I IX giving reMilP: of annU' i'. for met if-, amt uMu-r < t. n>< ut i will np|-at f<<llntviu|' line | i.ipi-*. in (tie mil tollin' i.|i*.i.ti of ibei \olnme of (tie ioonu.l I'lml... ..|.n n of dll' iipple lUeiil.liv innleinl limn till' |>npei imlv 01 toil o<< IIIU'i X I !! nun. I X rrilmlion. ue|;at ut ) i out inning all ol 1 bx MI(i|t)i |oeMrmi mntiiml /or lt>e j.itpei.. in ||.<^ i- ..o mny be nlilained fonn tbe .Imnnals | lepnit ment. Amemnn (.'lii'iounl Sorietv, ft'.'* Ifilti St , N W . tVm Jiinplnn, ft (!. ^OfUfi. Iteinil berk or money order for (X> for plx.tn copy or fJ fXI fur miln>fu tie. rrfettuig fa rodr nnintirr lAR'-7< ft'if MONS 086353 jj rcRAimiK crmi Cmlry, A . ft...... . V. W. f}m. M. H.. H. W.. Un.frr, M K.f'! IIm MMUftMI. Dm.wk ). M.. f il, |. H . Mmu, K. A.. An iw.Am ,1ft. V If, l>, J, A , Ollp o, K i< ,.l A turn AW >1. nttflDfl). Im..r.I> A . 0|l|< it, M n .,1 Af>.'n *' i H. 117(10775. P/f. M*. /,,./ u.....Im.l. IIU'OWII Knvirtuitiirntl Nniimml liiM'i'ilr of f'tivi- hintl.fitlnl llmllh Sitr-mn !<<> > li TAnnf;!* Orb, H. C., K** fiffimf n*) ! tir I In, V At'id l'.*/?. ... S',,-,, n oj-vn. run, Fltfl, 0 V,, Mnilow, <;. a , ,t. Af flfftr. Annl. Chfn Rf. 1002 1137.11, Frr, <* F,, 15. S, .!,, Cmilon, C. If., fluff. f`m>iro*i, f'oMin-i J'muof 7, 7'i2{!!*/?!, , Ff**, (5. 7., f! S . ilr , fJonlfw, <!. If.. J Agr. Point Chrm it, inrno.iF Grritiif, |`,, V'mi Sfwi. )*, J,. 11, S, ftrpitilmrnl of AgiimUtir* fJo 17't, I'*70. C'/ml, |5. b., Phillip*. 'v l'< !. Villrnniv<. |>, C-. Ihill. Environ Cnnltnn Tntttnl 11)7111*50. Oolrmnoou. '.V. It . ../ Apt. >W Or.-m. ft. 300<in<Vl|. lUnVm, I., HricUft. <!. ft . Hi<iwii, ii. A,, Clin, /'niinl. 12, C&t ftnhh. IV fl.OMl'V ),.Afir.J (Vm 4ft,?H!l'.(11WM. Kt'lor, P. M . OliamHrf, I' T,, Mlrvr. A. K., J Unity Sti f.O, WUP'lil) ` l#vj, I., )J<tibi, 'J\ \V,, flirll, f.'iinrrx* Cmilnm Tnn'rol. 7, 13.1 (1-177. MmmiI*. V., It., Nnfiirr (Inintintt) 17, 4) (lft`17). Mrittfi*. I) II., Ci1m7.iv II. H. H, hUrtr, V. A., HiMiwhtumJ, K. f*../ JAfrtrn*. 1). H., Mu.cr, F. A.. Cmdw)l, .1. H., J. f)nity Srf M, fllMMUlhl, * Mottf rw, f>, |l., V# Swl, l\S.,.r Aw'"i A'ci. 54, 77A{ISI7I>. Mitlfit, M, A., lifter. A. J . Sllrr. b. I),, McOevrm, J, N,, DO Ohrt, I). h.tJ. Amm ,SW. ,17, Ml!f>73>. J, )' , Slinml, 0. 11., Futr, ft, D., Hftfwn, l(. J. Anim.Eti. 27, Prof "It, ti ll . ((. // ,. tt. I fl ')77) j'lrtVitll, I). 111.. r 1, .1 fl.i.Sf I. ..r.- 7ft. P\A{ f*70 |V> l.r \P 'll M V11V, 1, U !i. 1 liirol Ilf tfr-r'l'l., {.iliMn.ii.it nit.l | V| a(,,J |l,iy A)rni>.i*linl mo. Wn-'l*. i'Hlim. !.<*., it vt* i'il, 1-ITt. ?.Vil...M /III Oi. 7i. 1 j.i noil f'litfrui'iiv. N , Ox I\ H V, Vl nrr fWim.*, n. s , 1 oi.tt.i5,11., nuHivb, i>i>. an. i.MtittnViT, r. w .c.irtp.n <: ,/ ri,,,.v r.{, t;*'ifi!7ii. I w. N t),, V/'iij').. n W, I'm V in..,111, .1. K, r,.u flmf Afr-rf |.V, r:''('>ll,//5. f Hi*iV, ,1. A, I- . fiti'ii'lii.r, |{.<:,, 7 a," Kri. Vl, ? 0 (I'f.ftl, SwrliMil.if'Vni. 1', NV . I'ltitnilt. II. S., N, ft,, \'rt n.r. ftiliii.rili.f, 11. A , Ah (p.ilitir M.T.'.|'rrt(i>t ?0)7, Arno*rni* I'f liitlrtim Itf'ltlii**.. "V.littipli.n. M (! . I't7<* Sr|| a X j11. It, Y. R . VfttMijn, S U ,.t. n..r It, V'UIV.H. !ir|itttt, .1, \V , 'li.i'r, ... CI . si .fi.litt; {. F... .If, Puffin. I Mritrit,. J) )( t |,|. V. I 1. P11PU11. llnll Irvinmt li.itlnni 7" Sl.nliinl. S. I., ........... if V.. It. I'.. MrNthirff, l>. *., 7Ai-vtf*.*. F., ................. urn r.ii.lmn 7ri'-'.l l. ( K*/ll SliMfi.il. I, |t. Mnn-f it. K. II .1 A itini .`if 1 \r.v17 <ri:n iibtntluv, It. F., Ur-diVfij. M. \V,, t)i.nn>^)i. ){. W,, 5*nl| {.Mi.iinrt (..moiii 7m in.,' f.. tfn(f'i/U Siuitlt'V, It I',. Mtillnt, A. A., IttrllliniH-r, f`, W . Hmlili titvt 21,71111071). Slnnitviib, It I* , filiittiii'rJ. S. J., Mm,ifl*i M, 7lrfl F'M'iioft r,,nrni.. T/I.iiIII in. tot (lfl/,11. T5ioii>". (i, M.. Hi viflil, I,. M.. Hi.(I TiitM'im ('niitnm Tmifof HI. .17(107.11. TIhhmiiii, .1 W., Vu. V . Hoffrr, 5 A.,.t Arum AV*. .71.7'.'.110705. TruliMil. II . Iti rnxl.r., Ann flmnn ft. 70,^17(1^.77. VilIrnfMVft, l). 0,, HovhoM*. b. M.. 'Iliitntn*. (5, H., Phillip*, W. .A**. (I/AV Anof.Chrm J.f.. `.m I If* CO (5. K.. Mi'i:tftVf. S. ().. Silmh, J. ().. MucVif nr, M. W.. J, Ooiry Sri. <1, .1t!M Rftrfivfd iot ffivirw April 12.1*174. Arrrptrd A**f*it 2. 1(174. MOWS 036354