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SSttuuddiieess TToo BBee MMoovveedd ttoo 88((ea)) DDoocekkeatt aEPA Submision Cherical/ Studs Submission Date Product Name SusTide Laboratory SudyNo. Dare StudyType Date Ch emical/ Product Name Study Title Laboratory Study No. Stud)' Date Study Type -- e carE e KooseOSuncrToerRatoy ahe emvroaremvne 460 ours fbSe=em rshers 04/21/2000 K PFOS Oral (Stomach Tube) Developmental ToxicRy Argus Research Laboratories, Inc. 418-012 01/11t1999 Health Effects: Developmental Study of PFOS in Rabbits Toxicit7 aE 04/21/2000 ao 04/21120G0 ws 05/041'2000 RKPEHOSTENS K PFOS; T-6245; FC-5 moses PFOS; PFHS; Fon PFOA; NSalen EtFOSAA; FOSA: Teale N-MeFOSAA: He PFOSAA; M570; feM556 oeApmos rom DEA PFOS; FC-99 BRRoETmp New Formula; T- Seg vos iawron Single Dose Intravenous frets Pharamacokinetic Study ofTmem 6246 in Rabbits. 3M Environmental Laboratory Samir soe Study #AM DT-042095.1 Pieovemcibows Fluorochemical Exposure Revvoeed Assessment of Decatur SGoOTA Chemical and Film Plant Employees Two esol Two Week Oral RE i R Tous uy Rangefinding Toxicity Study Tema 3M Te~nical esc Medical Oapement Department, 3M EV Company Shon, Riker Laboratories, Inc. feJ a Pmriemohs AMDT042095.1 11/11/1995 Health Effects: Pharmacokinetic & Metabolism Stutties eros EPI-O006 TORR) 179RR023 comes 08/11/1999 10 02/25f1980 temooms Human Data & oa Incidents: Medical ries Surveys, Clinical Sl Studies, Repor[s or Satins Sonar Allegations of Worker price or Consumer Effects ffnoEe Ace Health Effects: Acute Toxid~ JER 05/0412000 2509 CoC K PFOS of T-2509 CoC in Rats Stos Onl Toy (L050) Acute Oral Toxicity (LDS0) Study in Rats maart lntematior~al Reena Research and SeDevelopment Snr Corporation aes 137-083 css 05/31/1978 Teonnrecs Ace Health Effects: Acute Toxicity, [ES 05/04/2000 Goouaio 05104/2000 Goons 05/04/2000 K PFOS KprOS TENS K PFOS; %6295 KPOSTENS K PFOS; T-6295 vos ADwmic PFOS: A Dietary LCS0 i eitatan Study with the Northern SsBobwhite Tor eekDmy Cone 104 Week Dietary Chronic Toi rCacnohn Toxicity and Carcinogenicity rit Study with PFOS Potassium wa Salt in Rats IothekCgm Toy 26 Week Capsule Toxicity TOE IE, Study with PFOS; T-6295 in Siar: Cynomo]gus Monkeys i (Volume I and II) wbeenewers W~ldlife International aComrear. . .C.ovance . Laboratories, Inc. G Conee Laboratories, Inc. ison 454-103 nm 6329-183 nan 6329-223 oman 04126/2000 Enemraoe Environmental Fate pas & Toxicity Data: ATSat mee Avian & Other Wildlife weangtics. Health Effects: mares Carcinogenicity sar ~Studies owsfoSrresoainnbSscaoesi 04/~212000 Health Effects: Chemical-'Rssue Observations soz) 05/04/2000 50200) 05/04/2000 KPFOS TERNS Erowsey OnOm K PFOS; T-6295; es ae: Telomer Alcohol; ToomerAes Telomer Acrylate; HERE Cj5 pSoRheienEaH atReFaoyoves PFBS; PFHS ~Exploratory 28-Day Oral Toxicity Study wit,~ Telomer Alcohol, Telomer Acrylate, PFBS, PFHS, and PFOS (positive control) By Daily Garage In The Rat Followed by a 14/28 Day Recove'y Period mWaeynean 3M Environmental Laboratory (FACT) Pahercstyrds cds OrriTnet Say Eskaton Perfluoroethylcyclo jist =i hexyl sulfonate ERLE mn DEA Salt; FC-90: = %2960 CoC Acute Ocular Irritation Test with T-2960 CoC in Albino Rabbits Safety Evaluation Laboratories, Riker Laboraties, Inc. FA0CT3TOX FAC%TOX120.3 BKOEOLSS 0880EB0598 0811 HE est EteS c 06/11/1999 Health Effects: Subchronic Toxicity 02181081 HSeomnaEct:eer 02J18/1981 Health Effects: DermalfEye Irritation e113 Ex2h7i4b9it 22774499..00000011 PoEPA Suman Creme Submission peacrfeadheomSeusbTTe ALdaebowrna Date Chemical/ Product Name Study Title iS RpEmEeR n 05104/2000 PFOS Fiuorochemica! (FC) Levels in Naive Rats - Further Laboratory 3M wuiloe Dtseur_SsuutsTiyee Study No. Stud.v Date stu, Type To se gen T-6318.9; 5 aEma DT21 05/1411999 Envirormental Fate & Toxicity Data: Investigation of Rat Chow Other Environmental EH TEST 135/04/2000 PFOS Fluorochemical (FC) Leve!s in Naive Rats, T-6316.9 Bo=rs 3M Medical Department, Toxicology TQS316.9 05114/1999 Information mSem, Health Effects: Pharmacokinetic & Metabolism Studies on 05104/2000 on 05104/2000 i 05il 2/2000 pms PFOS; PFHS: WEEhS PFDS: PFOA; Si. PFOSAA; M556: M570; M463; M513 e mmre Potassium frye perfluoroethylcyclo ER hexyl sulfonate: TmEoRe FC-98; T-2308 CoC PFOS;FOSA: PFOA:PFHS pSSrHeRsC en Analysis of FCs in Samples of Children's Sera SmaImReE Acute Inhalation Toxicity Stuoy ofT-2308 CoC in the Rat m mmmmr Quantitative Analysis of FCs in Environmental Sam!31es Services sires 3M Environmental R=ET Technology & Services ar Bin/dynamics, Inc. MwoSwE 3M Envimnmental Labora~ (FACT) nsUWe FACT-GEN011 nw78-7187 ooFACT LEeEGen021, Gen024, gax5Gen030, sane 05~1/1999 samen 04/12/1979 ws 05/10/2000 nome Human Data & Eretriee Incidents: Medical Surveys, Clinical EreStudies, Reports or Eth Allegations of Worker or Consumer Effects sees et Health Effects: Acute etToxir.4ty peer Environmental Fate FB=a & Toxicity Data: Goneral a 05/18/2000 roa FOSA; T-342~ fmom amate Acute Oral Toxicity Screen fornia Gen033 Riker Laboratories 0883AR0287 or 01/17/1984 epedinpe Health Effects: Acute FE05/18/2000 05/18/2000 wn 05/18/200C N-EtFOSA with T-3421 in Albino Ra:s SRT A Developmental Toxicity Study of 313401 in Rats N-EtFOSA Sy N-EtFOSA; NEEEEE.. EtFOSE Alcohol; Primary Eye Irntatior~ mhmmmsm Bioaccumulation of FC in Tennessee River Fish Ir~c IT. V'4L Research Laboratories, Inc. Product Safety =Labs Memes 3M Environmental un Laboratory Tnic~ty 157016 wy Fwreeed 3871 nie smn = EpFroeene. ernr 78-2740 05/30/1997 Health Effects: Developmental Toxicity 11103/1995 Health Effects: Dermal/Eye Irritation 05/22/1979 Environmental Fate & Toxicity Data: rn 05/18/2000 mae 05/18/2000 N-MeFOSE AJcohol vero E eSFHE mEeeoennE Fn s . N-EtFOSE AJcuhol Absorption and -B]otransformation of N-ethyl FQSE and ~ssue Distribution and Elimination of Carbon 14 after Administration of N-ethyl FOSE14C in Feed eros fEseIam oy N-EtFOSE Alcohol Oral (Garage) Developmental Toxicity sw Riker Laboratories Inc. ar 0111911983 Bioaccumulation/Persi stence gmt Health Effects: pbeo, Pharmacokinetic & Metabolism Studies apoi era %6316.7; 418-011 12/17/1998 mes Health Effects: EEosm Developmental mae 05/18/2000 rca N-EtFOSE Alcohol Study of N-EtFOSE in Rats guste Oral (Stomach Tube) Paomhe, Developmental Toxicity pmamtms Argus Research Laboratories, Inc. aoiode41~-010; 6316.8 one 01/1111999 Toxicity untes Health Effects: pa Developmental Study of N-EtFOSE in Toxicity ners Page 2of3 Rabbits 22774499..00000022 EPA SSuubbEmDmiPasitAssesiioonn Date osrezun 05/18/2000 osrean 05/18/2000 osrezm 05118/2000 OStez 05/1812000 crazy 05/18/2000 S180) 05!18/2000 SSE 05,'18/2000 Osa 05/25/2000 casa 05/25/2000 PCCrhhoeedmmuiccictaalNl!/ame ee Product Name Ncn-EoetnrFOoesSeEfuzz Alcohol; FM-3422 SSttuuddyy TTiitllee Eason oie Evaluation of the Bacencansaion Penta of Bioconcentration Potential of ty FM 3422 eLLaaebboorraattoorryy LI3WMiEbEnenvvroirosonnm(eFennAstCalTl ) Laboratory (FACT) wesose N-EtFQSE Hora Tere Alcohol: %5874 nerosER N-EtFOSEA emstonate Determination of the PantonContant Partition Coefficient (nonanoi T8874 by octanoliwater) of T-5874 by Ri sarraren aud high performance liquid Srumtegasty (HPLC) chromatography (HPLC) Oelrrosin tpn. Determination of PhysicoCram Pupetiesst | Chemical Properties of Singeo Sample D-1 norox NOTOX tse Mitsul3ishi Crem Say Chemical Safety Ft Institute, Ltd. sNzEFOSEAT N-EtFOSEA; T- 6322 NAaEwCROSREanms N-MeFOSE Alcohol; FM-3925 TueryeshicaRepeuss Twenty-eight-day Repeated Dose GaiTouch Styl Dose Oral Toxicity Study of Srv Bm TAS Sample D-1 in Rats, %6322 DaSviuteonCnosaa Fl Distribution Coefficient of FM- 3925 in N-Octanol Water Seeses Bio-Medical Resear Research Umeseres Laboratories ILNaEorosome(rFiAsClT 3M Environmental Laboratory (FACT) NMSOSEAT. N-MeFOSEA: TShes5869 P3OSTED PFOSAA; %3290 CoC wmPROAT NH4 PFOA; TrarCre 397,4; FC-126 TPraOAlenFusItNerE PFOA emuisifier, T-6564:FC-1015 Densoofnt Determination of the Pon Coan Pollution Coefficient (nSars 4a octanol/water) of %5869.4 5 anporance Laue by high performance liquid remacashy HLC) chromatography (HPLC) AceOw Tort Soren Acute Oral Toxicity Screen wn TSRaCiC ARs with T-3290 CoG in Albino Foros Rabbits Pay Eemmenn Primary Eye Irritation in Rao Tae Rabbits, T-3974 Pray Ere Primary Eye mstonorSoesnoof Irritation/Corrosion Study of Te fa k ORE %6564 in Rabbits (OECD Coanioes) Guidelines) sorox NOTOX Riker Lavoscrer, Riker Laboratories, 1neInc. Cebseesatrns Hazelton Laboratories CIoneme Hasson Corning Hazelton Inc. SSttuuddyy NNoo.. SETOSIZ623 9570612623 2s 121275 SSDtuuadtdsey Date OM1BNSTS 08116/1978 oss 04/07,fl 994 SSttuuddyy TTyyppee Enonrersl Foe Environmental Fate &TonDui & Toxicity Data: Basmisinpers Bioaccumulafion/Persi ince stence EnvonmeFnaa Environmental Fate &Toutoats & Toxicity Data: [eb Bioaccumulation/Persi fry stence asses 4B223-4B227 BRC BMR 143C 1s 02/14/1998 ote 02/16/1993 EnwonmerlFan Environmental Fate & Tose Du & Toxicity Data: Bamscmianpors Bioaccumulation/Persi stence Hos hes Health Effects: SirchonsTorcsy Subchronic Toxicity SEYCIZEDD 9970012600 Tames %5869.4 OVENS 01/10t1979 oomsse 04107/1994 Ervine) Foe Er~viro~mental Fate Tonescui & Toxicity Data: Bavciminswpers: BioaccumulationtPersi stence EnvormensiFas Environmental Fate &Tou Oui & Toxicity Data: Sasamisnren BioaccumulationfPersi oer stence CHSIARCISZ | TIOSISR2 HTeoautchhyElects Acts 0882ARQ362 11/05/1982 Health Effects: Acute Toxicity 0050s 61005209 essCeHsCHW 60504574 Gurenss7 GMeoamniEtsec:sien 01/14/1987 - Health Effects: Dermal/Eye Irritation CoTI1SS6 HGeomaaiEgfyesmason 09/05/1996 Health Effects: Dermal/Eye Imtation Pigesors Page 3 of3 22774499..00000033