Document XzKVZL2jyBZeMa2nNm63dNa3x

fvuiiuiiiv wnvttmui wvmpuii]' *VI||Ulill VIIOIIIIIUI* IMVI9IV 800 North Lindbergh Blvd. St. Louis 66, Missotir CHEMICAL SPECIALT IES DATA REPORT The* information in this report was compiled to assist you in your evaluation and development of special uses for Monsanto products. Kvery effort has been made to include pertinent material benring on the subject. This information is intended to guide your development work, but Monsanto cannot tAke part in the specific formulation or evaluation of any finished product . . . since knowledge of such should be reserved to yourself and is often your most valuable trade secret. No. Date CS-6 March, 1961 MONSANTO AROCLOR* RESINS FOR INSECTICIDE FORMULATIONS A Discovery A simple method of increasing the service life of expensive lindane sprays was developed several years ago by U. S. Depart ment of Agriculture scientists at their Beltsvll.le, Maryland, testing station. The technique was to incorporate Monsanto's "Aroclor" 5^60, a resinous chlorinated terphenyl in the lindane solution. This pale yellow 3olid reduces volatility of thelindane -- slows it down to an effective, but not wasteful, evaporation rate. The result is an insecticide deposit on treated surfaces that lasts up to ten times longer than that left by straight lindane solutions". Normally, simple solutions of lindane leave a crystalline residue that dissipates within a few weeks. On hard surfaces such as glass, metal or painted areas, the residues last only about a week. Because lindane is a well established and effec tive pesticide, U.S.D.A. researchers sought a way to improve the lasting qualities of lindane residues. Of numerous com pounds tested, "Aroclor" 5A60 gave the best results at lowest cost. Test Work A major objective of these Btudies was to develop a suitable formulation for application to crops and other plants. Al though results under carefully controlled conditions were quite promising, subsequent tests by other agricultural ex perimenters gave only moderate success. Consequently, interest has been slow to develop in agricultural circles. Apparently, the vagaries of sunlight, weather, and plant growth represent too many variables for effective study of the formu lation residues by direct application to exposed plants. * Aroclor: Reg. U. S. Pat. Off. 0212803 The information In this bulletin la, to our best knowledge, true and accurate, but all recommendations or Nuggextion* are mad* without guurantee. since the oondltionx of uxe are beyond our control. The Monsanto Chemical Company disclaims any liability iocurrad in connection with the une ol tht-e data or suggestions. Furthermore, nothing contained herein shall be construed aa a recom mendation to ue any product in conflict with existing patent* covering any material or its use. ad 74 TOWOLDMON0043532 WATER_PCB-00028001 A New Idea But another possibility for putting the U.S.D.A. discovery to work has lain dormant until recently; this 13 the possibility of using to good advantage the ability of "Aroclor'' resins to make the lindane adhere to smooth hard surfaces like metal, glass, painted areas, etc. This would oonslst of painting or spraying "Aroclor"/lindane formulations on such areas as the Inside of garbage can lids, on window screens, doorsllls, the painted walls of outbuildings, dairy plants, storage areas, etc.. In order to obtain lasting control of files, ants, roaohes, silverfish and other troublesome pests. Suitable formulations can be readily packaged In shoe-polish type "dauber" bottles, aerosol spray cans, and bulk packages for meohanlcal Bpray application. Development of this idea 1b based on the following! Advantages of Using "Aroclor" Resins In Insectlclde Formulations * A suitable "Aroclor" (Monsanto makes seven) can remarkably extend the effective life of lindane and other chlorinated insecticides as much as ten times (up to 2 and 3 months). * "Aroclor" reBins are very low in cost (around 20^/lb.). * Small quantities are sufficient (5 to 25 parts per hundred, by weight). * Formulation is extremely simple -- the resin Is dissolved in a suitable solvent compatible with the insecticide. * Stable In inventory and in insecticide formulation. "Aroclor" resins are fire-resistant, non-oxldlzable, non-corrosive, withstand weather extremely well. * Non-stalnlng "Aroclor"/insecticide films formed when the solutions dry are practically Invisible. "Aroclor" 5460 has a pale yellow color as supplied. Other suitable "Aroclor" products are nearly colorless. , * "Aroclor" resins are odorless -- won't impart "chemical" odors. * "Aroclor" resins are safe to handle as long as they are not volatilized and inhaled. They are practically non-volatile at ordinary temperatures, do not Irritate or sensitize normal skin. * The nature of the residue can be varied. Monsanto supplies a variety of "Aroclor" resins. These are ohlorlnatod to various degrees and vary in physloal properties as follows! Monsanto Chemical Specialties Data Report CS-6, ....Page 2 OZI^01* | TOWOLDMON0043533 WATER_PCB-00028002 Aroclor 5560 Aroolor 54}t2 Aroolor 5465 Chlorinated Terphenyla Yellow, transparent, friable solid (drieB hard) Yellow, transparent, 3ticky semi-solid (dries tacky) Yellow, transparent, brittle reBln (dries sticky) Chlorinated Blphenyin Aroolor 1262 - Light yellow, sticky, viscous semi-solid (dries Btick Aroclor 1260 - Pale yellow, soft, Btioky semi-solid (dries sticky) Aroclor 1251* - Pale yellow, viscous oil (dries "wet") Experimental Work and Formulations The following Information was derived from preliminary reports on work done by U.S.D.A. research groups. These data are not to be construed as recommendations by either the U.S.D.A. or Monsanto, but rather are intended to serve as a guide or starting point for the development of private formulations. Fifty to 200 milligrams of lindane per square foot of surface haB given good Insect control on nonporous surfaces. The ratio of lindane to "Aroclor" 5460 has been varied from 1:1 to 1:4. For most purposes a 1:1 or a 1:2 mixture is satisfactory. Formulations as used in the U.S.D.A. experiments are: 1) For application as a solution. Lindane "Aroclor" 5460 Carbon Tetrachloride 5 parts by weight 5 parts by weight 756 parts by weight (Carbon tetrachloride 1b toxic and should be handled with extreme caution. Less toxic solvents are easily obtained.) 2) For application aa an emulsion. Lindane "Aroclor" 5460 Xylene "Triton" X-100 (available from Rohm & Haas) 20 parts by weight 20 parts by weight 100 parts by weight 3 partB by weight To obtain a stable 1# lindane emulsion, mix 1 part by weight of the above concentrate to 13 parts by weight of water. Monsanto Chemical specialties Data Report CS-6, .......... Page 3 0212805 | TOWOLDMON0043534 WATER_PCB-00028003 3) For use as a pressur.1 zed (aerosol type) spray. a) Lindane "Aroclor" 5460 Methylene chloride "Freon" 12 (DuPont) 5 porta by weight 5 parts by weight 40 parts by weight 50 partB by weight b) Lindane "Aroclor" 5460 Cyclohexanone Ortho-dlchlorobenzene "Freon" 12 (DuPont) 5 parts by weight 5 parts by weight 10 parts by weight 35 parts by weight 45 parts by weight Experimental Results - American Roaches Using Formula 3a or 3b, the toxicant was applied onto a painted wall, depositing about 200 mg./sq. ft. of lindane and a like amount of "Aroclor" 5460. When the toxicant coat was one month old, It gave 90-100# kill of Amerloan roaches when the roaches oontatned in a petrl dish were placed against the surface of the treated Wall for two hours. The U.S.D.A. research team found that the llndane-''Aroclor" 5460 mixture (used at the rate of 5 mg. of actual lindane per sq. ft.) would kill 80# of all cockroaches exposed for 2 hours to a bO-dayold treated surface. It remained lethal to 66# of the roacheB after 90 days. Regular lindane sprays used at the same rate killed only 4# of the roaches after 6o days. Results with Houseflies Deposits of 25 mg. of lindane plus 25 mg. of "Aroclor" 5460 applied from carbon tetrachloride onto glass and aluminum (hard surfaces) gave 100# kill of normal houseflies exposed for 2 hours to these treated surfaces after they had aged 18 weeks, the duration of the test. Without the "Aroclor" the hard surfaces treated with lindane alone were effective only about a week. A lindane plus "Aroclor" mixture sprayed as an aerosol onto leaves of a willow tree continued to kill houseflies after 2 months of outdoor weathering. Careful inspection of the treated leaves showed that the toxicant was held firmly to the surface and notwithstanding rain and weather, the costing re mained in good condition. Also, within limits of a preliminary inspection there seemed to be no in.lury to the willow leaves. Monsanto Chemical Specialties Data Report CS-6, .......... Page 4 0212806 TOWOLDMON0043535 WATER_PCB-00028004 (Note: The primary purpose of this report lo to provide in formation for the development of si.il table lnoectlci.de formula tions for application to "nonsensllive" surfacos such aa metals, glass, paints, and other materials that will not be damaged by the application. Development of formulations for living plants requires sufficient test work to insure that the formulations will not be injurious to the plants or their products.) Another Formulation Reported A more recent development in these experiments is the following simple formulation: "Aroclor" 5460 Lindane Methylethyl Ketone (MEK) 25$ 25$ 50$ Work on this was reported in the August 14, 1954 issue of Chemical Week magazine. This simple formulation appears to be most suitable for "painted on" formulations packaged in bottles but should be used with caution in mechanical spray equipment since the MEK solvent will Boften rubber and certain plastics. The formulation could also be modified easily for aerosol packaging. Since MEK evaporates rapidly, it should riot seriously affect painted areas unless too heavy applications are made. The package label should include a caution to this effect. Also, MEK is flammable. Possible substitutes that are less flammable are methylchloroform or a mixture of methylchloroform and methylene chloride. Formulating Other Insecticides The beneficial effects of "Aroclor" 5460 apply generally to other chlorinated insecticides including ohlordane, aldrin and dieldrin, but do not apply to phosphate type insecticides such as TEPP, parathicn, methylparathlon, malathion and chlorothlon. ' For samples of the "Aroclor" products mentioned in this report, contact the nearest branch office (see attached list) or write to: MONSANTO CHEMICAL COMPANY Organic Chemicals Division Plasticizers Department 800 North Lindbergh Boulevard St. Louis 66, Missouri Monsanto Chemical Specialties Data Report CS-6, ....Page 5 o?l287 | TOWOLDMON0043536 WATER_PCB-00028005 MONSANTO CHEMICAL COMPANY Organic Chemloals Division District Sales Offices ATLANTA: 1401 Peachtree St. N.E., Atlanta 5, Oeorgia BOSTON: Everett Station, Boston 49, Massachusetts CHICAGO: McQraw-Hill Building, 52 N. Michigan Ave., Chicago 11, 111. CINCINNATI! 2330 Victory Parkway, Cincinnati 6, Ohio CLEVELAND: *427 Hanna Building, Cleveland 15, Ohio DETROIT: 18230 Grand River Avenue, Detroit 23, Michigan HOUSTON: 2472 Bolsover St., P. 0. Box 6863, Houston, TexaB LOS ANGELES: 6670 E. Flotilla St., Los Angeles 22, California MINNEAPOLIS: Foshay Tower, Room 515, Minneapolis 2, Minnesota NEW YORK: 445 Park Avenue, New York 22, New York PITTSBURGH: 20 Cedar Boulevard, Pittsburgh 28, Pennsylvania SAN FRANCISCO! Ill Sutter Street, San Francisco 4, California SEATTLE: 911 Western Avenue, Seattle 4, Washington SYRACUSE: 731 James Street, Syracuse 3, New York WILMINGTON: 2005 concord Pike, Fairfax, Wilmington 3, Delaware ****** LONDON! Monsanto HoUBe, 10-18 Victoria St., London S.W. 1, England MELBOURNE: 256 Flinders Street, Adelaide, Australia MONTREAL: P. 0. Box 900, Montreal 3, Canada TORONTO 183 Front St. East, Toronto 2, Ont., Canada VANCOUVER! 1550 Rand Avenue, Vancouver 14, B. C., Canada 0 *v TOWOLDMON0043537 WATER_PCB-00028006