Document XzJBJDq99Op2zX8ERgmnkGqQJ

. . WaT7f 3M SM Spectaty Merit a Saenetm r s e . wee FYr-1202 001378 ARR26_ 1p8 ' : . December 16, 2002 VIA FEDERAL EXPRESS Document Control Office (DCO) OfficeofPollution Prevention and Toxics (OPPT) US Environmental Protection Agency E12P0A1 ECaosnts,tiRtoutoimon6A42v8ene, NW. `Washington, DC 20460 " I 1-00-001378 FY Attention: Docket No. AR-226 and the FYI Docket Dear Sir or Madam: `This continues `compounds, as 3M's voluntary submissionsofdata on part ofour ongoing dialogue with EPA perfluorooctane sulfonates regarding fluorochemicals, and related Included in this submission are the following: P"BaicoedAengarlaydtaitciaolnSSertvuidcyesR,epIoncr.t:StBuidoydeNgurmadbaetrioCnASOcSrSe,en3SMtuSdpyonfsororTeSltoumdeyrNTuympbeerAlEcOo1h-o0l6"8,4. + "Comparative Analysis of Fluorochemicals in Human Serum Samples Collected by 3M and Obtained Commercially", 3M Environmental Laboratory Study Number E02-1053. * 3"MAEnnvia roonflmEeny ndtoaslgei Lnaobs uosratFolruyorSotcuhdeymiNcualmsbeinrNEo0r2m-a10l39P.ooled Human Serum and Plasma", + "Analysis of Pooled Human Sera and Plasma and Monkey Sera for Fluorocarbons Using Exygen Method ExM-023-071", Exygen Research Study Number 023-082, 3MSponsor Study. CONTAIN NO CRI ---_----_--_--__t_------ 85030000001 TT I 000001 Page 2 Document Control Office (DCO) `The analytical method usedfor the respective analytical studies has been fully validated for PFOS in rat liver and plasma matrices down to 50 ppb. Limited cross validation for PFOS, PFOA and the other perfluorinated carboxylates in human sera and plasma down to 0.1 ppb was performed. Additional validation is recommended. Very ly your, We will continue to provide information as it becomes available. if you have any questions. Please feel free to contact me HkAE Ce: Dr. Charles Auer Dr. Oscar Hemandez Michael A" Santoro Director of Environmental, Health Safety and Regulatory Affairs Specialty Materials Markets 3M Center, Building 236-1B-10 St. Paul, MN 55144. EU 651-733-6374 (phone) 651-733-1958 (fax) 000002 z