Document XvoaMM2zaK6jvOQpO6bx3oBJ

.// Industrial Hygiene Digest INDUSTRIAL HEALTH NEWS LITERATURE ABSTRACTS MEDICAL ENGINEERING CHEMICAL TOXICOLOGICAL LEGAL * * - decision* and txanda MAY, 1933 (Vol. 17. No. 5) INDUSTRIAL HYGIENE FOUNDATION MELLON INSTITUTE 4400 FIFTH AVENUE PITTSBURGH 13. PA. MTOIt*C FOUNDATION FACTS /)> Foundation Faoto la a monthly nowo-lottor loouod to Industrial eoncorna holding momborshly In Industrial Hyglcno Foundation. Tha Foundation la a nonprofit aaooolatlen of Industrlas far tho advancement of hoalthful working conditions. Volume 15 May, 1953 PREPARATIONS FOR. ANNUAIy The Board of Trustees of Industrial Hygiene Yale Club in New York on May 27. One of the major item program for the Annual Meeting. The various Committees are also meeting this mouth to shape up plans for the Conferences to be held on November 18. The^Medical Committee met in Chicago -`.on May 6. The Chemical-Toxicological Committee has scheduled a meeting for May -20 at Mellon Institute. The Legal Committee will meet in New. York on May 26. A number of suggestions have already been received for the Engineering Conference ;that will.be given attention at a later date. DR. HUSSEY DIES ... -Dr. Raymond Hussey, Scientific Director of the Council onlndustfialHealth: :jo.r the American Medical Association, Chicago, died on Anril 15. DrHussey.was ^member of the Medical Committee of Industrial Hygiene Foundation from 1^42 to "- *4952 and of the Foundation's Air-Pollution Control Committee since its `formation ianr*' "1950. A ' ' ' '-.`'y- * ..i.r NOISE PROBLEM DISCUSSED .'V ..--j ' ... V- h Dx. Walmer presented a paper on "The Need for7 a Center .for.Coordinating^ ^ f'Data oh Noise (Historical Background and the Legal Problem)" at the IndustrialI.v- ^ health Conference in Los Angeles, Calif,/.which was held froth April 18 to;-25, .^jralmer^s presentation was'a part of the;Symposlum on Nbise, jointly sponsored by ^' -the Industrial Medical Association and the, American Industrial Hygiene Association;: v*. >held on April' 22.The paper was published in the May issue of Industrial Medicine?'. yand Surgery and reprints will soon be available. " -- ' NEW REPRINTS ! . . Reprints of a paper on "Noise, Its Effects and Costs" by Sam L. Hooper Sy(Remington Rand, Inc. j Past President, National Noise Abatement Council) are /available on request. The paper was presented at the 17th Annual Meeting of Ind- >.utrial Hygiene Foundation on November 19, 1952. *3: Also available are reprints of another paper given at the meeting on "Review Latest Developments in Outdoor Air Pollution." The paper is under the author ship of W. C. L. Hemeon, Engineering Director of the Foundation. HVOICNS FOUNDATION .. - I-H-F 4400 FIFTH AVINUI V FiTTsaunan (iX fa. :In<iu<trial Hygiene Digest - 21 May, 1953 494 A Critical Review of the Chemical Theory of Silicosis. Luise Holzapfel. Beitr. Silikose-Forsch. No. 15, 1-19 (1952) German. The solubility theory is first reviewed and reasons are given why it cannot be maintained in its original form, which says that silicosis is due to dissolved silica. The main argument is that silicosis requires years to develop while the solubility of quartz drops in the course of days or weeks. A modi fied solubility theory is suggested by the author's published work and on her recent results with carbohydrates. From plant extracts, a fraction containing carbohydrate and silica could be isolated, and experiments with blood and quart: showed specific adsorption of a galactose complex. The galactose adsorbed on quartz still reacts with hydrazine, demonstrating that the aldehyde group does not take part in the reaction with quartz. Next follows a very speculative _ chapter dealing with the structure of silica-galactose complexes. Collagen is said to contain galactose but there is no evidence on its structure. The osazone reaction can be used to demonstrate quartz in human silicotic lesions, as well as to demonstrate galactose adsorption on quartz, and a number of colored illustrations of this effect are shown. Electron micrographs of serpentine asbestos after disintegration in water are also shown. -- Cond. from Bull. Hyg. 495 Considerations on a Case of Progressive Massive Silicosis Following Past Limited Exposure. M. Bodo and L. Briccarello. Rass. med. ind. 21, 233-238 (May-June 1952) Italian. The authors discuss a case of progressive massive silicosis of the lungs which was seen by them in April, 1951. The patient was a metal work er, aged 28, who had been employed, 'for 2 years only, at chiseling grindstones in 1939-40. Signs and symptoms of silicosis, which are described, appeared in November, 1950. At the time of the examination, signs and symptoms were said to be stationary. .Tuberculosis was absent. X-rays showed a generalized deep and confluent shadow on the lungs, except for clear areas which may have been due to spontaneous pneumothorax or to localized emphysema. In the light of this case the authors question the statement that simple pneumoconiosis can be arrested by removing the patient from exposure to dust. The tendency to progress varies with the physico-chemical properties of the dust and the individual tissue reactivity. As in the case of hepatic cirrhosis, the causative agent may start a chain reaction which does not stop progressing after the cause has been removed. -- Cond. from Bull. Hyg. 496 Usefulness of the Photoroentgen Method in Silicosis and Asbestosis Investi gations of Workers? E. Zanetti. Rass. med. ind. 21, 130-132 (1952) Italian. A comparative study of several tens of thousands of photoroentgen films and roentgenograms has produced several interesting conclusions con cerning investigations of silicosis and asbestosis among workers. 35 mm. photoroentgen films were found to represent clearly massive silicosis, advanced nygiene Lugest - Z2. May, I'm asbestosis, and nodular silicosis. Ir. silicosis which is represented by reti culation,identification is more difficult^ hut it is still possible in the hands of an expert. The identification of mild or moderate asbestosis is still more difficult. Only a great deal of.experience which is integrated with a knowledge of concentrations and exposures of the dust involved makes possible an intel ligent interpretation of such films. - Biol. Absts. .i 497 Does Silicosis Affect the Silica Content of Human Blood? G. Worth and G. Campen. Z. physiol. Chejn. (fioppe-Seyler1 s) 288, 155-164 (1951). Gernsa#. The authors determined the silica content of blood of 264 persons, half of whom were coal miners with various stages of silicosis, using the molyb. denum blue technique.1 The mean result for the whole group was 8.3 + 2.4 micrograms silica per ml. of blood. Neither sex, different kinds of inflamma tory or other diseases, nor silicosis caused any difference in the silica content of the blood. Tests were also made after ingestion of organic silicon compound!. Here a rapid rise of silica content of blood and urine was found, but the blood silica had dropped to its normal value after 9 hours; The bearing of these find ings on the silica solubility theory is discussed. If the theory is to be main i tained, it must be assumed that the amounts dissolved are too small to be demon-': strated in the blood or that excretion through the kidneys is too rapid. -- Cond. from Bull. Hyg. 4*. ii to 498 Silicotic and Tuberculosilicotic Lesions Simulating Carcinoma.- F G. Kergin. J. Thoracic Surg. _24, 545-567 (Dec. 1952). ir The appearance of unilateral massive densities in the-lungs of eight men between the ages of 49 and 69 with chroftic pneumonitis has been reported. In each of these patients clinical and radiographic evidence strongly suggested bronchiogenic carcinoma. Five of the eight patients had prolonged exposure to silica-containing dust in various occupations. Five patients were treated by % pneumonectomy, one by lobectomy, and one by thoractomy and biopsies were made. The fundamental feature of the pathological process in this group of $' patients was complete or partial bronchial obstruction by pressure of lymph nodes, which were the site of a chronic inflammatory reaction secondary to inhalation of silica-containing dust. In five patients the chronic obstructive pneumonitis was non-specific, and in three there was an added tuberculous infection. It is suggested that this condition be called "chronic silicotic lymphadentis with obstructive pneumonitis (nontuberculous or tuberculous)." The I 4 patients are all alive; the six patients treated by excision have been relieved of their complaints. -- Cond. from J. Am. Med. Assn.