Document XR8MppraYaZ0qV0xggBmw40eG

,','J ' -. "t f\ 401# JO I- 42nd St. Kr * *. &Us (2) U .v/*- - i 4 - . ,-rt mr ? * If l < * Ir* 17# I* S >3 4;'. February I94A Ri > 4P _,-' . ' :$$.' . <Tp>'> - - *-' X^iik *v ' - * 14.'-;^ Boor Mr* Hsllasi Or* Oroe asks in his report of call of l/fi/48 to Corbett Clinic, Chisago, If Sr, Corbett*# practice of applying our filo# VB-1925 and VB-1900 clear directly to the akin In his treatment of lmbago and sprains, etc,, is dangerous. Would say that applying these films directly to the skin and keeping In continued contact night lead to o dermatitis in seme few indiTiduals, partly because of the lmperviousneas of the film and partly because of the sensitising action which the film might cause In some few oases. We hare patch tested VU-1900 dear on 151 human subjects and found that in 13 per cent of them some sensitisation reactions did occur* Wa bare not patch tested VB-1925, but hare the basic resin,the VZHW, and found that it did cause o slight reaction in 8 per Cent of the subjects. Also the stabiliser used in TB-1925, arm in 1 concentration on gause, caused definite sensitisation reactions in about 9 per cent of the subjects tested. However, should such sensitisation reactions occur during treatment such as Dr. Corbett Is dairying out, they would probably disappear with no residual effects upon discontinuance of such treatment. So X would say that applying our films VB-1925 and rj-1900 dear directly to the skin is not dangerous. Such application might cause a dermatitis; in some popple, which would dear up in all probability upon discontinuance of the contact with the filn. Very truly yours, T, b W, Wale1 M, D. IHDUSTRIAL TOHCOLOGX DEPARTMENT UCC ' 063514 ._