Document VyeVmxdVBvqGzn5L8pyQzO0q

AR226-2778 FOR DU PONT USE ONLY E. I. du Pont de Nemours and Co., Inc. Haskell Laboratory lor Toxicology and Industrial Medicine Elktton Road, F. 0. Box SO, Newark,'Delaware 19711 HASKELL LABORATORY REPORT NO. 736-81 Material Tested Octanoic acid, pentadecafluoro-, ammonium salt* Haskell No. 1) 14,180 2) 14,181 Study Initiated/Completed 10/20/81 - 10/21/81 t a w ! -----Material Submitted by Textile Fibers Department Richmond p p p W jOqCLUDED SKIN TEST ON RABBITS Summary:(`^ ^ ^ l i l m p r e g n a t e d J ' f i H I B ^ c impregnated{jHHBQstrips were apprled to rfhaved intact rabbit skin for 4 hr, 8 hr or 24 hr. After each exposure period the rabbits were unwrapped and the exposed areas wiped with ethanol:water (50:50) soaked gauze pa^ s . All wrappings and pads were then sent to Textile Fibers Department f o r U H B H P ^ a n a l y s i s . No skin irritation was observed during the study. Procedure: The purpose of the study was to determine the amount t if a ny, of im S H t h a t might migrate from the fabrics to the skin on the rabbits backs. fw_e_nt.__y_^one mal e_ *N_e__w_ _Z__e__a_alanjd tWi LhJite rabbite *s wer e cIlipped fP wraea^ oa f( khaa4iri* movrea rr pthh ea back and trunk areas and J it ted with clastic collars. f l ^ M i m p r e g n a t e d IB l B B J s t r i p s o r f r B f l B A m p r e g n a t e d y | | | ^ B V j s t r l p s were applied to the back of each_rabbit. Three rabbits aervetr as controls and were wrapped with a o n - H f l V R r e a t e d material. The trunk of each rabbit was wrapped with a layet of plastic wrap, gauze Stretch bandage and adhesive stretch tape. After 4-hr, 8-hr or 24-hr exposure periods, the wrappings were removed and the exposed areas were wiped With gauze pads which were soaked in a 50:50, ethanol:water solution. The atnimals were observed,after unwrapping,for skin irritation. Yarn fibers and gauze pads ware returned to Textile Fibers Department for analysis. ' - 1- ompany Sanitized. Does not contain T S C A C8I Results : Haskell Mo. 14.180 14.181 Controls Exposure Time 4 Hr. 8 Hr. 24 Hr. 4 Hr . 8 Hr. 24 Hr. 4 Hr. 8 Hr. 24 Hr. * Composition : 1) H-14,180: 2) H-14,181: Other Names: Skin Reaction None None Nne - 2ofTspSRv nanltizeo. T S C A C'.' Approved by; LSP:jrg :WP:12.17 Date Issued; January,28. 1982 Report Ho. 736-81 Gerald L. Kennedy^ Jr. Section Supervisor Acute Investigations - 3- s not contain TSCACBl CoiW ^SaniU "0"