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WEBSTER 3-6111 R I K E R L A B O R A T O R I E S , I NC. LOS AN GELES. CALIFOR N IA ( Et iia a C eS i aia tie.i. MAI L a d d r e s s : P. O. BOX 3157 TERMINAL ANNEX LOS ANGELES 54. CALIFORNIA Jun e h , 19 53 R o b e r t A . Ke h o e , M. D . The K e t t e r i n g La b o r a to r y o f Ap p lie d P h y s i o lo g y Ci n c i n n a t i 19, Ohio Re ar R r . Keho: I t v a s a g r e a t p le a s u r e t o c h a t w i t h yo u d u r in g my v i s i t t o Ci n c i n n a t i a f e v weeks back In acco rdan ce w ith yo u r re q u e s t I s e n t you an a d d itio n a l s u p p ly o f c a lc iu m d is o d iu m EDTA upon my r e t u r n t o Lo s A n g e l e s . I t r u s t th a t i t reach ed you in good o rd e r. I am w o n d e rin g i f yo u h ave be e n a b l e t o g e t th e i n fo r m a tio n on th e c a s e s t r e a t e d i n Panama by R r . K i t z r a i l l e r a s y e t ? We wo uld be m os t g r a t e f u l f o r a ch an ce t o lo o k a t t h e s e c a s e r e p o r t s o r a t l e a s t a summary o f th e r e s u l t s when yo u have be e n a b le t o e x t r a c t them from our La t in Am erican n e igh bo rs . I am s i n e t h a t yo u h ave s e e n th e r e p o r t b y R r . S id b u r y w h ich ap pe are d i n th e Pro ce e d in gs o f th e S o c ie ty fo r Expe rim e n tal B io lo gy and Medicin e r e c e n t l y i n w h ich he p o i n t s o u t t h a t o r a l c a lc iu m EDTA pro du ce d a d e f i n i t e i n c r e a s e i n le a d e x c r e t i o n . On th e b a s i s o f t h i s i n fo r m a tio n we a r e some w h at e n co u rage d t o c a r r y on some; f u r t h e r s t u d i e s w i t h th e o r a l m a t e r i a l in asym ptom atic c a s e s . I f you would be in te re s te d In h avin g seme o f th e ta b l e t s t o t r y i n t h i s c o n n e ctio n we would c e r t a i n l y be happy t o send them to yo u and would va lu e yo u r im pre ssio n o f th e ir p o s s ib le u s e fu ln e s s . Thanks a g a i n f o r th e p l e a s a n t c h a t w h i le I was i n Ci n c i n n a t i and f o r a l l th e in fo rm atio n you gave me. S in ce re ly yours RIKER LABORATORIES, INC N W K i g N o rm an W. K a r r , M. R . D ir e c to r , Ch e m ical R e se arch N9774