Document VZ56j5ZzGXVgkOGBepo1QD2g

1 start out with a larger number. Page 2246 2 Q Other witnesses have told the jury because 3 you would expect to see really only one to two cases 4 of mesothelioma per million in the general population. 5 And if that is true, then you would need a 6 very large cohort, for example, in order to study what 7 exposures would lead to meso? 8 A That is true. If disease is rare, you need 9 more people. 10 Q That is one of the benefits of a case 11 control study? 12 A Potentially if the cases and controls are 13 collected properly. If you don't, you can bias the 14 study very easily. 15 Q Okay. I think you testified that asbestos 16 is toxic. 17 Can you tell me what you mean by toxic? 18 A Well, hygienists, and I think the public in 19 general refers to toxic as the ability to cause harm. 20 Frankly, if you look even in the toxicology 21 literature, you will find things like asbestos and