Document VKLjGN3QgndvnpNbYqEaqE4j8

MANUFACTURING CHEMISTS ASSOCIATION 1825 CONNECTICUT AVENUE. N. W. WASHINGTON. 0. C. 20009 (202) 483-6128 RECEIVED NOV 2 9 1971 lR- n. wheeler TO: Vinyl Chloride Producers November 19, 1971 Subject: Trace impurities in vinyl chloride Gentlemen: Interested members of the vinyl chloride industry are now considering a proposal to conduct studies in which animals will be subjected to long-term exposures to vinyl chloride monomer. In order that the test materials be properly representative of current American practice, we are requesting that you provide the following data on (a) your current industrial product, and, (b) a "highest purity" product you would be willing to provide in tonnage quantities to a guaranteed analysis specification. Requested Data 1. Production process (identified by appropriate patent refer ence or commercial process description.) 2. Raw material source, i.e., acetylene from calcium carbide, from hydrocarbon cracking, etc. 3. Assay: Minimum % Typical_____% Maximum------- % 4. Identified impurities: Minimum Typical Maximum a. ppm PPm ppm b. ppm ppm ppm c. etc. For each item under question (4) please identify method of analysis and limits of detection. A copy of the list of the im purities reported as being in material used in an earlier Euro pean study is attached for your information. -1- UCC 000446 Particularly for compounds that may be suspected of being highly toxic or carcinogenic (such as methyl chloride, methyl bromide, or bischloromethyl ether), presence or absence at the fractional ppm level may be of interest. Sincerely, KDj/cj Enclosures Staff Representative -2- ucc 000447 Impurities Present in Vinyl Chloride Monomer 1,2 dichloroethane 1,2 dichloropropane Tetrachloroethylene 1,1,2-trichloroethane Acetaldehyde 1,2 dichloroethylene-trans 1,2 dichloroethylene-cis Chloroprene Methylene chloride 1,1 dichloroethane Carbon tetrachloride 1,1,1 trichloroethane Chloroform Trichloroethylene Benzene Water Ethane Ethylene Propane Isobutane Carbon dioxide Propylene n-Butane Acetylene Cyclopropane 1-Butene Isobutene 2-Butene-trans 2-Butene-cis Allene 1,2 Butadiene Methylacetylene Methyl chloride Ethylacetylene 2-Chloropropene Ethyl chloride 1-Chloro-1-propene-trans 1-Chloro-1-propene-cis n-propyl chloride Vinylidene chloride Isopropyl chloride Vinyl bromide n-pentane Isopentane Methane Mercury ucc 000448