Document VJ0KQkprOOJ5MO4zd1Nk9V37q

Page 1809 1 mesothelioma occurs over a many-year period and all of 2 the asbestos contributes to the development of the 3 tumor, as we understand, by the mechanism of cancer 4 development. 5 One could maybe wonder about when the tumor 6 actually started and nobody knows that for certain, 7 but most data suggests that it starts many, many years 8 before a person clinically presents with the tumor. 9 It probably was there 10 years before he 10 developed symptoms and maybe longer. 11 Q Ten years before symptoms would have been 12 sometime in 1928? 13 A That is correct. 14 Q Is mesothelioma,in your opinion, a 15 cumulative exposure disease? 16 A It is. 17 Q What does cumulative exposuremean, what you 18 have described as each exposure? 19 A Yes. And another way to look at it is dose 20 response, the more a person is exposed to asbestos, 21 the higher the incidence is of that type of cancer.