Document VGxoRdM96mbxb2D8NG29Ee7Vp

Th e Pe n n s y l v a n ia St a t e Un iv e r s it y 226 CHEMICAL ENGINEERING II UNIVERSITY PARK, PENNSYLVANIA 16802 Center for Air Environment Studies Area Code 814 865-1415 Form Approved Budget Bureau No. 85-S69020 Reference Number.: 27.5b AIR POLLUTION RESEARCH PROJECTS 1969 If you have research projects during 1969, please complete the entire questionnaire. If you have no air pollution research projects during 1969, please check the box below and return, p--| Organization: Address: Eden Avenue, Cincinnati, Ohio 45219 Title of Project: Hunan Exposure) to Particulate Lead Compounds in tile Air Under Experimental Conditions Principal Investigator(s): Robert A. Kehoe, M.D., Professor Emeritus Cin charge) with various members of the Staff of the Kettering Laboratory -principally, J. Cholak, Professor (and Chief Analyst), Lawrence J. Schafer, Assistant Professor (and general Supervisor), and others (physicians, clinical mlcroscopists, biochemists) Location of Research: Kettering Laboratory Expected Duration of Project: General investigation of lead metabolism in human subjects has been under way since 1939; will continue indefinitely - the practical problem of the tolerable concentration of lead in the ambient air is but one phase. Or community health since in Brienf Summary or DDeescr` iption: Has been supported supplied for a period of five 1th Service, Division of Air PollutS (SEE OVER) Title(s) of Resulting Paper(s), Author(s), Journal, Volume, Date, and Page(s): (SEE OVER) Please indicate, on back of one of the report forms submitted, names of i Raymond Suskind, M.D., who will be here by the middle of August. trector, V, V SUMMARY : Brief summary useless. The purpose has been that Of determining th level of the concentration of lead in the air which when added to the background of other environmental factors (chiefly that in food and beverages) can be handled by the excretory, mechanisms of the body without any measureable elevation of the daily output of lead or any measureable increase in the concentration of lead in the blood - that is without measureable indication of an alteration of the equilibrium now being maintained (by normal individuals) between their intake and output of lead during prolonged periods (months and years) of experimental observation. PUBLICATION : Incomplete - periodically in relation to significant results of prolonged experimentation, by RAK, speaking for the group in publications best d described as Progress Reports. (1) Kehoe, Robert A.: The Metabolism of Lead in Health and Disease. The Earben Lectures of 1860 - J. Roy. Inst, of Public Health and Eyg. 24:(April) 81-97, (May) 101-120, (June) 129-143, (August) 177-203; 1961. (2) Kehoe, Robert A.: Experimental Studies on the Inhalation of Lead by Human Subjects. Pure and Applied Chemistry 3:1-2, 129-144, 1961. (3) Kehoe, Robert A.: Criteria for Human Safety from the Contamination of tne Ambient Environment with Lead. Proceedings of the KV International Congress on Occupational'Health, Vienna Austria, September 1966, Vol. Ill, 83-98 - Verlag der Wiener Medizinisehen Academia, Vienna, 1966. KE 0019698