Document VGJzq66YEx60omqY0d8dKKROj

Page 57 1 this is the kind of thing I talk about regarding state 2 of the art? 3 A I'd be happy to. 4 Q Okay. Would you please do so? ; 5 A Sure. With respect to asbestos and state of : 6 the art I would say that asbestosis was thought to be 7 occurring, they didn't know it was asbestosis, but some 8 lung ailment in the early 1900s right at the turn of 9 the century. It took until 1930 for them to know that j 1 10 asbestos did cause a unique disease called asbestosis. 11 That's made very clear in Meriweather and Price. 12 In 1955 the suspicions that sufficient doses of 13 asbestos in one form or another, if the dose is 14 sufficient, can increase the risk of lung cancer and 15 that's Doll's paper. 16 In 1960 Wagner is fairly certain that the 17 amphiboles can cause an increased risk of mesothelioma. 18 In 1964 Selikoff shows that things that were 19 thought to be not of significant risk with respect to 20 end product insulation, he finds there's an elevated 21 risk if the dose and duration are sufficient, certainly 22 for the amphiboles. 23 And then there becomes a regulatory flurry of 24 activity that begins around 1970 and continues through 25 1994. And that's both in the United States and in ; j > ESQUIRE DEPOSITION SERVICES (415) 288-4280