Document VG169EMZmN7LnEZOGqGgb7qK4

FILE NAME: Oil Industry and American Petroleum Institute (API) DATE: 1951 June & July DOC#: API025 DOCUMENT DESCRIPTION: Letters, Memos, Reports, Financial Reports & Other Relevant Documents from June & July, 1951 u t TIRIN O lao o n ato n y L| .a OF N I0 ICIN I t o o eton"*ti ' 0M, AVtMUC i UNIVERSITY OF CINCINNATI DCPABTIKMT o f FU V tN TlV Z U IC IN I ANO IN D U fTU A L HIALTM January 1 2 , 1951 ,L/ V o< C A B U ao o n cas, a i u i . Cin c in n a t i T1U VN O M : CAMTOL UM Mr. D. V. Stroop, .American Petroleum Institute, 50 West 50th Street, yew York City 20. Dear Mr. Stroop: I herewith acknowledge with thanks receipt of American Petroleum Institute's check in the amount of $9,005.12, covering payment " due January 1, 1951 for experimental work to be done on their P behalf. Very truly yours, E . F . Fortlag' D r . Kehoe Secretary to s/ \ \ \ \' API 05050 API 05051 1 r UNIVERSITY OF CINCINNATI OEFAHTMEHT OF PREVENTIVE MEDICINE ANO INDUSTRIAL HEALTH tH l UTTER.N IA.OEATOET Zat<*f" DlclHI-tDINAVMUI CjgCINNATI I OHIO January 2 3 a 1951 Mr. d . V. Stroop American Petroleum Institute 50 West 50th Street Nev York City 20 Dear Mr. Stroop: Thanks very much for your letter of December 20 to vhich my reply has been delayed because of a brief holiday at Christmas time and because of the difficulties ofgathering up all of the ends since. I write primarily to call your attention to a fact that is of some consequence in connection with the fourth paragraph of your letter. As it happens, Doctor Townsend has retired from his activities in the Industrial Hygiene Division of the United States Public Health Service, and his place is being taken officially on February 1 by Doctor Seward Miller. My own acquaintance with Doctor Miller is utterly indirect, but he is well known to Doctor Phair, and we have no doubt that we shall be able to maintain wholly satisfactory relationships with him and with his whole group. The fact that this group is in Cincinnati, and that they have actually gone out of their way to create and maintain good relations with all of u s , is sufficient indication, I think, of how the wind blows. There is no reason that I can see why you might not find out the reactions of your people toward our collaboration with Doctor Miller, in a manner as close as that of our collaboration with Jim Townsend. Obviously, we shall proceed with every possible care and discretion, and we shall also undertake to know how the present situation develops in this phase of the work of the Public Health Service. All I can say at present,is that one or two of the people we know rather well in the group are rather pleased by the appointment of Doctor Miller, and feel that it augurs well for the future. We shall keep our own counsel on this matter, but will certainly do everything we can to maintain wholly satisfactory relationships. You will be interested in knowing that the financial support for the continuation of our investigations on fluorides has now been assured. The original agreements with the sponsors in this relationship terminated at the end of December. However, all of the people continued in their interest in the matter, with the single exception of the Du Pont group, who may well have had good reasons for following up more extensive interests in other directions. At any rate, they are sponsoring other work hre in the Laboratory, and therefore we do not feel any great let down from their decision. Their place has been taken, in the financial sense, by the Tennessee Valley Authority. Moreover, we anticipate obtaining additional funds from other sources, and I am making such efforts in that direction as seem feasible. In any case, we shall be able to continue through the present year on an unabated scale of investigation. API 05052 I I Mr- D. V. Stroop - (2) - January 2 3 , 1951 With kindest personal regards, Sincerely yours, RAK ef Robert A. K e h o e y M . D> API 05053 M. IM. N E W O U IS T . M. D. M ED IC A L D IR E C T O R THE TEXAS COMPANY 135 EA ST AZ'iP ST R E E T NEW Y O R K 17, N.Y. December 12, 1950 MArm. e Dr i.c a Vn . P S e troop trole u m Institute 50 West 50th Street New York 20, New York Dear Mr. Stroop: After discussing with you Dr. Kehoe's letter of November 1 5 , 1950, I have come to the following conclusions: 1. Sending a copy of the report to Dr. Hine seems to be In order 2. The studies on the carcinogenicity of certain petroleum fractions at the Kettering Laboratory are continuing and Dr. Kehoe's report rendered prior to the recent API meet ing is in the nature of a progress report. Therefore, dlstrioutiDn of this report should be very definitely limited. The Medical Advisory Committee of the API has recommended the exchange of information as we go along, with the Institute of Petroleum in London which has been represented by Colonel S. J. M. Auld. I would be In favor of latting Colonel Auld have two or three copies for the use of his committee. If he or the committee of the IP wish to release any or all of the information in Dr. Kehoe's report to Dr. John Rogan of the Medical Research Council which is a governmental setup, I presume that would be his own business. I do not think that it is our place to recommend it. 3. In connection with Dr. Townsend, I think we should drag our feet for some time yet. The principle expressed in Item 2, above, is applicable in that the studies are under w a y ana this is o n l y a progress report. Therefore, a re port should not be rendered to Dr. Townsend at this time. API 05054 2 3 Dr. Heyroth should be able to handle his situation on a verbal basis only and I feel that that will satisfy the parties concerned for the time being. ij.. Dr. Kehoe's comments with reference to the hydro fluoric acid review seems to be appropriate. Very truly yours MNN-gh cc: Doctors. Kieffer Davis B. B. Reeve Mclver Woody API 05055 I / towtfter , 1 0 B r, Robar! A . la te a galtarsltgr of Ciao In n ati X atterlag Lab an tary of A ffilia* A jilf llo ir ra In a rtt 19, Ofalo Baar B ester afana i te la r r y l? te ^oar la t ta r a f la te n te r 15 baa baaa dalajad bjr ajr abaaaeaa Ares la v lorie aad agr teafa te rii imana ju a r re ro-- nricfirma a lte Doctor Woody, ate ocatlaaas te aorta aa cfaalxaaa a f tea sabeatadttaa <mC a rcla o ja a lclty a a t il Tlancnhwr 30, na* a lte Doctor te a q a la t, ate a l l bacca* te* a tilim v ftta * e te ln a a aa a r aeaa fte r aanargr 1 . Ha a te n te tnrjr fia d te tefaa car* a f tea ragaast 70a re ca lta * trm t e t a lia * S t e lla r i? aa afaall tete jra a ft n a tica a jtmt n m m t lo a nbaa t Baater Tote Bogteu Aa aoaa na tea alaatea of tea lo a Anadea acat ia g ara n i f i ate* Baater facaAy, na afaainaa of tea anbsoaaltt** aa Caeelansaalelty# t e li aaa* aayias o f tena Ite caftan a f tea SeU arlag reyerta te C alcas! AalA, la asaeteas** te te te* laflaraal eooysratlta m a p a n t as catrtllnfaa* sea* fata* ap< Za A la la t ta r a f ti esani t ta l Doctor Veo*? t e li atete ja sa raacaaaaiatlea nbaat Beater Jaba Anana lfa* raicU naafaly batacna Baater in cassa* na* fai* gruny na* tee telo n i A rlaery CdM ittas la s t i l i a b it fan7 la toa In sita * te nttaa* tea eem nltts* aaafin g la Los ln U i, na* 1 fa s i tara tea com i tesa t e il te te fala te fas* aste la fcn a a tlsa na pal* basa basa osallahA* te fata a t ten aa*tin g i faaanscr, ten nanas te te st aa* re arte? fnrtfacr ce n a lia ra tlna. te t e a ll ifa n w r te aoonre a teyrote. M assa acaayt car tenate fa r je s r carneas! nbont Doctor It e r coaacat ca ten b ftro fla a rl* n a l* Batear la nppraelate*. a cay? la b a ia i aaat te Bocter C1 la to s. I m aara ba t e li rita te jo s i nagr fB M tlaa n rlao a. 818 ta cat Doctora Klafffar Batea I. Baagalat 1. 1. Basta citar 00*7 API 05056 Doctor M. I . le v a a la t Doctor Molvor WocCjr QcbIm m u PungueoI r o a ( H l f t re p ly te Doctor Khoa'a le tta r of Tf u te la i 15 (a eopy o f te le * la aaln--i ) tea tea ra ja ra >1. Ib 1 2 v ltB car raoaot eomwreatdU*. P ic a rea l t e r lt la a lly . IT yoo h a n aosgastlena b r atenga* placee le t se teta tte a oa or te fcre Daetebar l t . ID tte ate ence of o tjeetlco a reoolrod ty tte t tSaa tte le tte r a l l te aalled te Doctor lo te e . v t7 to ral/ you ra , DVBsa oes t e . E le ffa r Darla t e . . B . Beata API 05057 S2 X m jw tw m or Protetti* Ih llitw ato Xafetftrlol la tito eiail-- tl 19 l o 19, 199 , 9. . seroof j^ rle o n P o tre i It e t i tote strato gvvTBrfe e i v Dato i r . strooft X Ocold bevo wU aa oceu l r far tolti ito job at lo AagelM, tot tisi pto u d meato to te filini, oo tot X w | rito atemt o ft Batter. Vltk n|Mt to tl ilatrltotiaa f a v rtycrt, X b m o noto fn> Setter Ila, teo attonito tto ti oo teOalf of Itoli, rofa-- tlag o eojgr of ho nyart. loo ili kaov totOar or aot to 1 tolti* to lt, u A lf to 1, to If o ay la ndliUa, fra a a ot a-- trilaglf H a lira la Ojo t o Strato, toarfrllla, callfavolo. Attaollf, to tto potiti-- oooaplto to Itoli alto rtp*ot to atdlaal rtjrt-- afcatloa, lt 1 alfaatagtoat to to alla to tool trito o pOptlelaa ataoclatti alto ttoIr ootiritira. Ubo* I oo in Loto-- Z aot Ito tto g r erlrtog oo tto I r lt lt o iro O lta tOroogO tto eo artetj jf Deetot Jo ta agaa zi tto --l ie t i 2--oareO C a to ill, Oo 1 tto a c a ti rf --e rtte rp f tto fa a ttlta la g g r . Colpool 8. 4. II. Aul or vita tal g r ad vae ot un notlag. l t la agr t o a t llt r t i rtm --nadatlo* tto t la fa ro o rilag a aopf f tto rap ar* ta Coloaol A a li, fa r tto O rltlaO fto re lta a la t t i ta te , oo a d iltla m l aoju te a lt o rai ia ti to Dottor Sogni altO or tOroogO Calcool Aa li or ilr t t o l/ . XOia to o OlgOlf rotyaotlO lo graap ItO Oca o, p re fe ttio te U f tp--k iag , -- auto v a r i r w j a lo e tlf, it o Ito Oca, tto la ia t t r j, laolaA lag tto t la tO lt ramtr7 , Oooli te on tto te s t ito m a la to to n a . I topo to te aoia to toa Dottor io rto a or Dottor B tjro te T lt lt un ot tin to aoa la tto aot tee A lateat fa u n a , la o rio r to tote toteaftogt of t t e lr t r i ta te la tOl f i a l i f o ri. gorlag ateo tto poppola t it a anootorf to eolloO orotlaa ito to n i X ItO to fo llo ttroagO Ito appropriate orartetp . I op ali aa* to rito to Dottor Sogaa lo t e la t i-- to tto t aotte r, te ttartfaro jaar aotlaa, poar lovpolat, ai tto loto of A.P.I. la tto aotter ili iotomlao, la por*, Oot I abol oop. Culoool Aali 111 Altea tOla aotter ItO tto pooplo la oap eoa, a tOeoli tote tto AAltloaol aetloa atnittory to rtop tto tatto la goto 111 7 tto xrsia t e n t o ai Ola gr. X Otoli lite Tooaatai to bava o aopp of tto rapar* te Ola 1iteraitloa. 901 eoa 0 aolo at ctafUotolol at aop te ioolrto, ltOar Oy ay lo11og ItO Ola ilraotlp ai la 0tarlitato, or Of 01 telag appUto ItO a roport fra* /oar offlto. Ite teiltltaal paia* lo tOot ot Dottor loprotO'i ralatie-- Olp te tto Poaal oa Tarir-- atei Carar of tto aatltaol t o n n o Conoil. to rfrt arai aot te toc amllaOlo toc, tot lt ili te noicmy far Sagrato to tool frooklf ito 01 oli-- g a tOl laaol, Ite roopott te tto API 05058 m I w . . T . Stroop J 15, 199 y H ia , INI, M M i -- taallp IM nulte af tkia wrk a a l o tter S aft a 4a Im t e il fla lA . I m m haha mm a f h l-- i r u l a f th ia altemtiom u i M p m rte te h t , hat i l 1 ohrloaa t e il ha i -- t m U i m t H a i of aaaraap v ith raapaat ha It e patralamm ia a a *7 , a-- p t in raapaeh ha r t r la t l/ ao afliam tlal lm fanatlam . pat 1 haf-- all, x aaaha ha m ap arlhialmi ULI aaaa aa aa i t ha h in . Z aa ha teim 41-- hljr, a-- p% far faah hhah lh la ho da! through pou. I athaeh harata a fer oha-- mitten li Im p--11 am M* f * hha aa4 ra a la v 7 . Hr vlhh tha jra a ia a u i ao ai n iflk.eh ace, out t hm 1 hgr thaa w ill, Z ha m aconthlp claar. Zf th-- la I ' i ha gla to am C llstan 'a A H la a ll tha -- h in la Laa / -- l n -- jpaUfyiJM I ha a a . r n p i m ia h alas aada am a -- har f frooha, a la v lj hut -- ly . V ita teT-- a l -- la , M l af Sw. * QmrAJtellp paar, /*/ iateu*t A. ahoa la h m A. Sa-- , M. S . API 05059 1 i Citflaitt 19, CU M r Doctor totasi ftli raply ti |r lotear f M m 1? feu tes talaya* Ay m t t e w M fte t e Krk n i ay vite te llareta jaw reeameadatle* vite M W Vooy, tea nntolrere te esrre aa tea 1rata of tea MAoaatottea re Ciinlaatre1r1*rr atll Baoaater 30 ate vite Botter Bavfalat, tea vlll Maaaa tea auliaiittaa oAalrrea re r aore after JAnrery 1. Va a to ll te re ry g la* te tato ara o f tea raq reat iv a raoalvta frm Doctor Hlao. Slallarly va atoll teto jrrept retire re jnr aaiiatlre otate Poster Jato Bogaa. Aa aare aa tea alretoa of tea Laa Iagolea aaatlag ara eoaglate* Doeter VooAj) aa oAalraaa of tea Sateore&ttea re Carolaagatealty vlll aote ooplea of tere vite eaploa f tea totearlas raparte te Celaaal Aal la aaaeraaea vite tea laTerrel eooperatira a m a p r e t aa eetaAUaAto aare tire age. la Ala latear af traaaatttal Doeter Voody vlll atete yoar m iarenflntl m bout Doatar Jo ta Bogaa Tto ra la tie re A l? te tre aa Dooter Tovaaeto ata Alo grrep ato tea tolaal AAvlaory Cnrertttaa la o tU l a A lt to sy. la rea ir r it a i ta ateato tea aerettea aaatlag la Loa Aagalaa, ato I f r e vara tea cre a ltte a v l l l v ito A la t tova eveA la fe ra a tlre aa v o a li Aova Area avallaA la te A la a t tea aaatlag ; Aovarer, tto reare te tto t ato ara vartey of fv rtto r earelA ero tlre. Va a to ll aalaavrr to aaaara a oaereare oa te la meare la Pleaae aaaayt ear tto ato fa r jo u r ereaoto otate Doeter leyrotfe. Toar ooaaret re tto A y iw flu rla a e li ftarlev la appraeiate*. A oopy la Aalag o ret te Dooter C U atea. X re rere Aa v l l l r it e te yo if rey taret ir e a rla re . Yeiy troly jours# DIB ta oai Dosto ra . U o fT ar D arla I. I w p irt 1 . 1 . Breva m i m e VooAy fa Aa algato Ay D. . Stroop API 05060 rom th# offico of DAVID V. STROOP O..M. .... V" 0 mots Jp ^ T C o P* f s f c t API 05061 f , U T T U IM 6 LABORATORY OF MEDICINE-- ADAM AVAMMI j j r CIMMATI 1 . OHIO 1 I UNIVERSITY OF CINCINNATI DAPARTMENT OF PNSVBNTIVt MEDICINA AMD INOUETRIAL HEALTH November 15 > 1950 CABLA A D M ASS ATLAS. CINCINNATI TELEPHONE: CAPITOL I4M Mr. D . V. Stroup, American Petroleum Institute, 50 West 50th Street, Mew York City 20. Pear Mr. Stroup: I should have made an occasion for talking with you at Lcs Angeles, hut time sped and seemed to he filled, sc that.I must write about a few matters. . With respect to the distribution of our report, I have a note from f Doctor Hine, who attended the meeting on behalf of Shell, requesting a copy of the report. You will know whether or not he is entitled to it,and if he is, and if a copy Is available, you can act accordingly. His address Is 456Q Horten Street, Emeryville, California. Actually, in the position occupied by Shell with respect to medical representation, it is advantageous to be able to deal with a physician associated with their activities. When I was in London I met with the group working on the British problem through the courtesy of Doctor John Rogan of the Medical Research Council, who is the executive secretary of the functioning group. Colonel S. J. M. Auld works with this group and was at the meeting. It Is my considered recommendation that in forwarding a copy of the report to Colonel Auld, for the British Petroleum Institute, an additional copy be made available to Doctor Rogan either through / Colonel Auld or directly. This is an highly responsible group with I whom we, professionally speaking, should work very closely, and with whom, the industry, including that in this country, should be on the test and frankest terms. I hope to be able to have Doctor Horton or Doctor Heyroth visit some of these men in the not too distant future, in order to take advantage of their experience in this field of werk. Having made the association necessary to collaboration with them I wish to follov through with appropriate courtesy. I shall want to write to Doctor Rogan in relation to this matter, and therefore your action, your viewpoint, and the wishes of A.P.I. in the matter will determine, in part, what I shall say. Since Colonel Auld will discuss this matter with these people in any case, we should take the additional action necessary to reap the utmost in good will by the exercise of every courtesy. . ' There is also the question of our, relationship with Doctor Townsend and his group. I should like Townsend to have a copy of the report for his information. This can be made as confidential as may be desired, either by my dealing with him directly and in confidence, or API 05062 1 t Mr. D. V. Stroup - (2) - November 15, 1950 >,tt his being supplied vith a report from pour office. ir^he additional point is that of Doctor Heyroth's relationship to the panel on Environmental Cancer of the National Research Council. The report need not be made available here, but it vill be necessary for Heyroth to deal frankly vith his colleagues on this Panel, vith respect to the/purpcses, scope, methods and eventually the results of this vork and'other vork ve do in this field. He can take care cf himself and of this situation in an appropriate manner, b u t it is obvious that he cannot act in any kind of secrecy vith respect to the petroleum industry, except in respect to strictly confidential infor mation . Finally, having gone ever the revievs recently put out before publi cation, I have certain editorial suggestions to offer on the material on Hydrofluoric acid. I spoke to Marshall Clinton about these very minor matters, so that my criticism vill come as no shock to him. I vould make my recommendations to him directly, except for the fact that it is good form to deal through you. I attach hereto a copy of the^ reviev vith the suggestions for change vritten in in pencil on pg. 6 and 7- My precise vords are of no significance, but the ideas repre sented by them vill, I think, be reasonably clear. If there is any question on Clinton's part, I 'd be glad to correspond vith him. All in all the meeting in Los Angeles vas gratifying to me. Progress is being ra de on a number of fronts, slovly but surely. With kindest regards, Cordially yours HAS ef Enc. API 05063 1 i UNIVERSITY OF CINCINNATI w u n m ornuvann i w a n and indurbul maltn ,anu lamoatoot orumiciw-- n n avuihc a ,,eidAATI W . OHIO cam*ambo* otiaa.cimcmbati tunmii cAftm iam February 6 , 1951 Mr. D. V. Stroop Director Department of Safety American Petroleum Institute $0 West 50th Street New York 20, New York Dear Mr. Stroop: I have returned finally to Cincinnati and before leaving for Florida for a short vacation, I wanted to drop a note thanking you for meeting with me Tuesday, January 23 during my recent visit to New York. I was very happy that I again had an opportunity to dlseuss with you the various problems which we have encountered In organising our epidemiological studies. It is certain now that after we have been going for awhile, many of the apparent obstacles will fade away. There is a need, however, for the partici pating medical departments to continue and extend their cooperation, insofar as feasible, in these projects of the Medical Advisory Coasdttee if the standards of medical care in the petroleum industry are to be raised. It is my hope that all of the companies will establish a firm policy regarding this participation In the near future. There is a tremendous need, as I attempted to point out during each of my visits, for a united front. I know that you are In agreement with me about this question. With very best personal regards, I. am Sincerely yours, API 05064 r t ' January 3, 1951 AIRMAIL Dr. "ohn J. Fhalr University of Cincinnati The Kettering Laboratory College of Medicine - Eden Avenue Cincinnati 19, Ohio Dear Doctor Phair: This is to acknowledge receipt of your letter dated January 5th and to let you know that the week of Janaary 15th probably will be my busiest week this winter. My personal obligations are such that I cannot make any promises to see anyone during the first five days of that week. If you will telephone after you arrive in New York, we may find time to get together before you return to Cincinnati. Sorry we can't make a definite date at this time. Sincerely yours, DYS:rd t11 API 05065 (IlfA111* H T T iR *" uaronatort OF M E D ICI-- iolU 1 of 0 gClpPAJT|I 1#. OHIO I UNIVERSITY OF CINCINNATI DEPARTMENT o r PREVENTIVE MEDICINE AND INDUSTRIAL HEALTH CAALK A0 ONCSS: U T LAS. CINCINNATI TCLVHONK; CAPITOL MI4 January $, 1951 Mr. E. V. Stroop Eirector, Eept. of Safety American Petroleum Institute 50 West 50th Street New York 20, New York Dear Mr. Stroop: I am planning a trip east to review with the various medical directors the present status of their arrangements to report cases under the API project. I want to discuss at length also the proposal to assemble certain descriptive material regarding the various refineries and other installa tions of the participating companies. I have advanced the date of this trip due to other commitments and plan to leave here January 10, reaching New York via Pittsburgh, Washington and Philadelphia. Can I see you the afternoon of the 17th? Will you answer as soon as possible so that I can make final arrangements. With the season's greetings, I am Sincerely yours, JJPthp API 05066 r u t t er in laroratort [ u s e of m edicine- eden aven u e ^,eiit**TI" 0H' i UNIVERSITY OF CINCINNATI DEPARTMENT O r PREVENTIVE MEDICINE AND INDUSTRIAL HEALTH 71StT'US.r*'*?' 24 > 5C"1 CABLE ADOBEIS: EETLAB. CtNCtNMATl TCLEFMOME: CAffTOi. MM ylV. 3 . V. Stroop py-e American Petroleum Institute =0 Vest 5 ith Street Vev York City 20 Dear Mr. Stroop: ~ I send you herewith, for your information, a statement of expen ditures made on behalf of American Petroleum Institute during it :he fourth quarter of 1950. I believe that the statement is self-explanatory, but if you have any questions or comments, Doctor Kenoe would appreciate your bringing them to his attention. Very truly yours, 3. k. t ortiage /Secretary to D r . Xehoe v I API 05067 UNIVERSITY cf CINCINNATI 2ETTERING LABORATORY ACCOUNT 0? AMERICAN PETROLEUM INSTITUTE FOR 'THE FOURTH QUARTER 1950 (Based on Proportion of Time Actually Spent on Project) Robert A. Xe'noe Il Francis Heyroth John Phair Wesley Horton I Frank Cleveland Fred Shaffer Russell Tye Ruth Pierle % Dorothy Templeton Waldo Younker Robert Lampe Marion Duvall 'tnvT.IAJTSOUS EXPENSE Supervision Toxicological Assistance Coordination of Experimental Work ` Pathortlogical Assiitstance Technical n n it it Assistance h n n it n 100.00 31.25 1375-02 20.00 1050.00 II2 5 .OO 517.12 47p -55 317.35 3 3 4 .00 7153.20 purchase of Animals Laboratory Supplies ........................................ 190.30 1213.50 Traveling Expense ........................................ 1512.90 proportion of Secretarial, Library, Janitors, Wash Boys, Draftsman, Shipping Clerks, Animal Caretakers, Histopathological preparation etc ....................... Proportion of Heat, Gas, Electricity, Steam, Telephone, Postage, pensions, Annuities, Maintenance, Animal Food and Supplies etc ...................................... :o.;c 3263.92 TOTAL Balance Available for Work in 1950 at Ena of 3rd Quarter 1950 . . Expenditures - 4th Quarter 1350 . Balance Available for Work in 1951 at End of 4th Quarter 1950 . . 19, 974.93 $71,442.01 1 9 ,974.98 51,467.03 API 05068 Copy from D. V. Stroop for Information of Members and Associates of the Medical Advisory Coanittee. _________________________________________________ 3-26-51 MORT GILBERT OL. 1^00 X 658 CLINTIE KENNEDY OL. 1^00 x 2137 FEDERAL SECURITY AGENCY Public Health Service National Institutes of Eealth National Cancer Institute FSA-B30 FOR RELEASE THURSDAY, MARCH 15, 1951 The possible harmful effects of certain petroleum products and radioactive ores and dusts from uranium mines and mills, of key importance in the Nation's defense effort, will be tested on laboratory animals in two university research centers through Public Health Service cancer control grants, it was announced today by Federal Security Administrator, Oscar R. Ewing. Drs. John W. Mehi and Hugh A. Edmondson at the University of Southern California School of Medicine, Los Angeles, will study hydro carbons found in crude oil and in products formed in oil refining and catalytic cracking. Dr. John Z. Bowers will establish research facilities at the University of Utah, Salt Lake City, to expose animals to dusts under conditions similar to those found in uranium mining and milling. These grants are two of a list of 22 special control grants which have been approved by Surgeon General Leonard A. Scheele of the Public Health Service following recommendation by the National Advisory Cancer Council. The grants going to the University of Southern California and the University of Utah are part of a program to foster cancer prevention studies in universities located in areas where possible cancer hazards occur. Southern California is an oil-producing area which is subject to waste fumes and gases from oil refineries, and Utah is the scene of extensive uranium mining and processing. In both these areas, environmental cancer field surveys supported by the Public Health Service are now in progress. The special cancer control grants of the National Cancer Institute are awarded to State and local health agencies, universities, hospitals, and other non-profit organizations to assist the development of cancer control methods and services. A list of the control grants follows: API 05069 * ? t SPECIAL CCIOCL GRANTS Cli-=rnia INSTITUTION & LOCATION AMOUNT GRANTED California State Department $ e,5co of Public Health, San Francisco, Dr. Wilton L. Klaverson SUBJECT Occupational cancer of respiratory tract. University of California at Los Angeles, Los Angeles, Dr. Andrew H. Dowdy 23,995 The evaluation of a seroflocculation reaction as an aid in the detection of cancer. University of California, San Francisco, Dr. Herbert F. Traut 5,*2U Cytology training center. University of Southern Califor nia School of Medicine, Los Angeles, Dr. John W. Mehl and Dr. Hugh A. Edmondson 19,116 Investigation of potential carcinogenic environmental hydrocarbons. University of Southern Califor nia School of Medicine, Los Angeles, Dr. Edvard G. Jones and Dr. Ian Macdonald 9,560 Epidemiologic study of uterine cervical cancer. Colorado University of Colorado Medical Center, Denver, Dr. James J. Waring 18,000 Occupational cancer survey of the State of Colorado. Connecticut Yale University Medical School, New Haven, Dr. Ira V. Hiscock Maryland University of Miryland Medical School, Baltimore, Dr. Bussell S. Fisher 25,000 6 ,26h Teaching program for health administrators in cancer control. A study of precancerous changes and carcinoma in-situ in the human uterine cervix during pregnancy. Missouri Washington University, St. Louis, Dr. Evarts A. Graham 9,568 Experimental production of cancer by tobacco products. New Jersey New Jersey State Department of Health, Trenton, Dr. Carl E. Weigele 36,950 Survey of occupational cancer in.the State of New Jersey. New York Division of Laboratories and Besearch, New York State Depart ment of Health, New York, Dr. Bfrank Maltaner 12,300 Memorial Center for Cancer and Allied Diseases, New York, Dr. Allen 0. Whipple 12,722 * Continut ion grants Immunologic studies of cancer. Experimental surgery. API 05070 * -3- % *mm *r-r SPECIAL CONTROL GRANTS (Cont'd) INSTITUTION & LOCATION AMOUNT GRANTED SUBJECT \v Y^rlc '(C -. ",,ia"'^J'^ New York University - Bellevue Medical Center, New York, Or. Locke L. Mackenzie $ 2,592 Detection of genito-uriary cancer by means of betaglucuronidase enzyme, and correlation accuracy with cytological diagnosis. North r >_roLinZ O h io The Bowman Gray School of Medicine of Wake Forest College, Winston-Salem, Or. Robert P. Morehead 3,29^ The Ohio State University, Columbus, Dr. Madge T. Macklin 10,300 Pennsylvania Trustees of the University of Pennsylvania, Philadelphia, Dr. George C. Lewis 10,000 Establishment of a tumor follow-up service, and provide material for a course in oncology. Role of heredity and milk virus in causing human breaBt cancer. A study of the geometric distribution of radiation during the treatment of carcinoma of tr.e uterine cervix, with reference to both the survival rate and the damage of contiguous pelvic viscera. Texas Nix Tumor Clinic, San Antonio, Dr. Eudley Jackson University of Texas, Medical Branch, Galveston, Dr. M. Mason Guest 7,9kC 5,022 Study cf breast secretions: cytological pattern as related to type cf breast pathology and hormonal unbalance, and comparative study of ceil types in tissue culture. An investigation of the fibrinolytic enzyme and inhibitor systems in blood and urine. The University of Texas, M. D. Anderson Hospital for Cancer Research, Houston, Dr. William 0. Russell 6,000 Microbiological assays of blood from cancer patients. Utah University of Utah, Sale Lake City, Dr. John Z. Bowers District of Columbia Georgetown University Medical School, Washington, D.C., Dr. Charles F. Beschickter ' Continuation grants 19,602 3,650 Cancer hazards associated with the mining and milling of uranium ores and other radioactive materials. Follow-up and experimental production of benign and malignant bone tumors. API 05071  -u- STATE SFECIAL CONTROL GRANTS (Cont'd) INSTITUTION & LOCATION AMOUNT GRANTED SUBJECT Territory of Hawaii, Depart ment of Health, Honolulu, Dr. Walter B. Quiaenberry $9,178 A study of hospital records for the past 10 years to determine the morbidity of cancer. * Continuation grants Total special cancer control grants $26^,977 API 05072 e' ? H >VVw>7ve -- ------ A i . f - - i T r e i C T U-V. 1lV .2-l-iA'l \X UNIVERSITY OF CINCINNAtT DEPARTMENT OF PREVENTIVE MEOICINE AND INDUSTRIAL HEALTH ,u i eettewn laeon atm t L U S F MEOICINE-- EDEN AVENUE Se." '*0H` Aprii 2, 1951 CAELE ADONE**; KETLAE. CINCINNATI TELEPHONE: CAPITOL MM Mr. D. V. Stroop, Director Department of Technical Services American Petroleum Institute 50 Vest 50th Street New York City 20 Dear Mr. Stroop : I send you herewith the account of the receipts and expenditures in connection with the prosecution of the investigation of fluorine compounds in 1950. Since the receipts and expenditures for the prior years were reported, and since any debit or credit balance of funds was carried over from one year to the n e x t , the present account portrays the financial status of the project at the end of 1950, with the exception indicated in a footnote on page 2. Inasmuch as the deficit of $2,026.20 can be carried over into 1951 (the project is to continue with the support of most of the previous sponsors plus certain others), there seems no necessary reason for dealing with this matter at this time. However, any disagreement with this viewpoint should be expressed, and if there Is such expression, it will be transmitted to the other sponsors. The work will be continued under the sponsorship of the following groups in the amounts pledged per year and for the total periods 4 specifically designated: * K. Contribution Further Commitment 1951 Pennsylvania Salt Mfg. Company Reynolds Metals Company 2 ,ooo.oo 4 ,000.00 Year to year Presumably 1 addi- tional year Tennessee Valley Authority 4,000.00 3 additional years Aluminum Company of America 4,000.00 3 additional years Kaiser Aluminum and Chemical Corp. 4,000.00 American Petroleum Institute 2 ,500.00 Universal Oil Products Company The Harshaw Chemical Company 500.00 1 ,000.00 1 additional year Year to year 2 additional years Year to year The final report has been in my hands, for such further consideration and editing as may be required, for some v e e k s . Mr* Largent`s task in preparing it was considerable, as is that of studying it critically. I must ask your indulgence in the matter of the time API 05073 *aken thus i*ar 2111(1 required further to complete it. For a number * reas0ns, vhich probably require no elaboration, I have had to alce ay contribution to the report as time could be found. Such f7Be has been fragmentary, but progress is being made, and, one ;'jsts, will be more rapid from nov on. n-he bibliography on the organic compounds of fluorine has progressed, hut since it is a heroic job, and since further time will be required to"complete it, Mrs. Campbell has set it aside for the moment in c-der to bring the section on inorganic compounds up to date. This "s being done with my approval in the belief that the latter may have greater immediate usefulness than the former. -"he other work of the library, as of all other divisions of the Laboratory, has increased greatly. Another library assistant is being sought for employment. This will not increase the cost of the library work for this project, but rather it will enable us to do more work for other sponsors. Comments and suggestions will be welcome on any phase of this r e p o r t or on unreported matters. Sincerely yours, i PAK ef i Znc F.obert A. Kehoe API 05074 i ) OTIV28Ir CP CUiCIKHAI AccoggXrETHERnIaBOflLoABoOrRiAseTOpRkY ojict 1950 (Based on Proportion of Tino Aetually Spent on Project) Robert A. * * oe ranci* Eeyroth jacob Cbolak yard Lergant i_lao Blackston jla Zollar Robort Hesterberg Morris Blaeknton Aston Hieb#1 Bernard Signan irvm Spottoi K*therile Largent Richard Suelotto David Cain irono Campbell yrslyn Vldaor - Supervision - Oearel Technical Supervision - Supervisin of Analytical Work - Principal Investigator - Experimental Subject - Technloal Assistance - Literature Berlov - Literature Berlov rtT.T^wopa E X P O S E 350.00 9*.03 242.30 2622.24 580.00 623.06 307.56 1 0 2 .0 0 630.18 936.14 673.73 640.00 r?9.24 323.74 495.00 11,123.31 laboratory Supplies............................. X-rays of Experimental Subjects ........................ rood and Expenses Incurred In the Collection of Staples by Experimental Subjects......................... * Proportion of Secretarial, Library, Vash Boys, Shipping Clerks, Draftsman, animal Caretakers etc . . . . . . Proportion of Seat, Oas, Telephone, Poe tags, Pensions, Annuities. Postage, Maintenance etc .............. 2.705.77 78.00 2,001.00 5.256.38 3,634.22 TOTAL $25,004.18 API 05075 I i  9 2 - B6l*ie# tanalnlng f r a 1 9 * 9 .................................. $3,*77*98 /{bla Isoliate $1500.00 racalvad tram 4-- rioin patrolaiai Institute in 19*9 for sa in 1950) gaaalpts - 1950 $8*,500.00 for orar d m f t 19*6 far ovardraft 19*9 8000.00 *000.00 6.000.00 L^sriug far Uso in 1950 ................................ i goti! 6 * Tiilatols far Uss in 1950 . . .......... 18.500.00 21,977.98 gotti Espanditurai In 1950 .............. .. 85. 00*. 13 orordrift of Xxpandlturss orsi* ipproprlatlan 1950 ir 3,026.80 Ab iddltlanal sia of $1000.00 to laro b m siqiplled by Onlvarsal Oli Frodxaots Oo^iny, ss not pald in tbrough an ororsisht. ftais hns sin boon pai* (nftnr jaauary lst, 19517 and ia Tallitola to radusa tba orardraft in dioatad atooro. fhis trasse tiaa vili appair in ttoa aeeounta for 1951* API 05076  3 M * * W <* >-- r U + t i n of l y w M X t d M ........... .. j*0lpt 1950 .............................................. $4000.00 4000.00 0 - Mtrolmm Institat sbtro of l i p M M i X t a d M d .............................. punte t e t e l n d Is 1949 far Dm is 1990 ........... .. 1900.00 1500.00 f. I. SM n at m a i l u I t r t n l ................................................000.00 teoolpta 1950 4000.00 y^eylvesls salt Rfg. Caspasp otite of b p m M z t s l A ........................ .. Punte R i N l r i d for 19*8 ippropristlao paste Raoairte far 1949 appropriation 8000.00 4000.00 8808780 teeaipta far 1990 ............... .. 4000.00 4000.00 4000.00 PMMO a n t a tetla Coop oration (Kaiser Aluminum and Chemical Corporation) I b o * of lapon as z t a d t e i ........................ .. Bolpta 1990 ............... ......... 8900.00 2500.00 Insalda Mtala o-- p -- p State af T i p i a Zt o n i a t e ......... ................... t e e a l p u 1990 . ................................. .. 4000.00 4000.00 fetonti oil P r o t e t Cony n j Stasn af t e n t e a Zt o n i a t e ............................ Batesa da os 1950 S h a n of Kapos 1000.00 Total S n Du . . . . . . _ _ .................. .. 1000.00 1000.00 API 05077  A m e r ic a n P e t r o le u m In st it u t e 8 0 W EST BOth STR EET NEW YORK 20. N. Y. tnruorr or technical a n tv ic u ^ david v. rrnoop, d h c i n April k, 1951 To Members Subcommittee on Fluorides Gentlemen: For your information we enclose copies of two communications, as follows: 1. Letter dated April 2, 1951 from Robert A. Kehoe, M.D., giving account of receipts and expenditures in connection with the prosecution of the Investigation of fluorine compounds in 1950 at The Kettering Laboratory. 2. Letter dated March 20, 1951 from H. P. Caldwell outlining research project at Boyce-Thompson Institute to study fluoride damage to vegetation. Very truly yours, D V S :c Enclosures me: Members and Associates, Medical Advisory Committee API 05078 (C 0 p Y) UNIVERSITY OF CINCINNATI Department of Preventive Medicine and Industrial Health Tbe Kettering Laboratory rolle&e of Medicine - Eden Avenue Cincinnati 19, Ohio April 2, 1951 Mr. D. V. Stroop, Director Department of Technical Services American Petroleum Institute 50 West 50th Street New York City 20 Dear Mr. Stroop: I send you herewith the account of the receipts and expenditures in connection with the prosecution of the investigation of fluorine compounds in 1950. Since the receipts and expenditures for the prior years were reported, and since any debit or credit balance of funds was carried over from one year to the next, the present account portrays the financial status of the project at the end of 1950, with the exception indicated in a footnote on page 2. Inasmuch as the deficit of $2,026.20 can be carried over into 1951 (the project is to continue with the support of most of the previous sponsors plus certain others), there seems no necessary reason for dealing with this matter at this time. However, any disagreement with this viewpoint should be expressed, and if there is such expression, it will be transmitted to the other sponsors. The work will be continued under the sponsorship of the following groups in the amounts pledged per year and for the total periods specifically designated: Pennsylvania Salt Mfg. Co. Reynolds Metals Co. Tennessee Valley Authority Aluminum Company of America Kaiser Aluminum & Chemical Corp. American Petroleum Institute Universal Oil Products Co. The Harshaw Chemical Co. Contribution 1951 Further Commitment _________________ $ 3,000.00 k,000.00 Year to year Presumably 1 additional year If,000.00 3 Additional years h,000.00 k,000.00 2 ,500.00 3 Additional years 1 Additional year Year to year 500.00 2 Additional years l, 000.00 Year to year The final report has been in my hands, for such further consider ation and editing as may be required, for some weeks. Mr. Largent's task in preparing it was considerable, as is that of studying it critically. I must ask your indulgence in the matter of time taken thus far and required further to complete it. For a number of reasons, which probably require no elaboration, API 05079 Mr. D. V. Stroop (2) April 2, 1951 j ^ v e had to make my contribution to the report ae time could he found. Such time has been fragmentary, but progress is being made, and, one trusts, will be more rapid from now on. The bibliography on the organic compounds of fluorine has progressed, tut since it is a heroic Job, and since further time will be required to complete it, Mrs. Campbell has set it aside for the moment in order to bring the section on inorganic compounds up to date. This is being done with my approval in the belief that the latter may have greater immediate usefulness than the former. The other work of the library, as of all other divisions of the Laboratory, has increased greatly. Another library assistant is being sought for employment. This will not increase the cost of the library work for this project, but rather it will enable us to do more work for other sponsors. Comments and suggestions will be welcome on any phase of this report or on unreported matters. Sincerely yours, RAK ef Enclosure /s/ Robert A. Kehoe Robert A. Kehoe, M. D. API 05080 f f UNIVERSITY OF CINCINNATI KETTERING LABORATORY ACCOUNT OF THE FLUORINE PROJECT 1950 SALARIES (Based on Proportion of Tine Actually Spent on Project) Robert A. Kehoe jTancis Heyroth Jacob Cholak Edward Largent Elmo Blackston jim Zoller Bobert Hesterberg Morris Blackston Anton Michels Howard Sigmon Erwin Spettel Katherine Largent Richard Sucietto David Cain Irene Campbell Evelyn Widner - Supervision $ 350.00 - General Technical Supervision 9U.03 - Supervision of Analytical Work 2L2.30 - Principal Investigator 2,622.2h - Experimental Subject - Technical Assistance 58O.OO 623.06 - Technical Assistance - Technical Assistance 807.56 102.00 - Technical Assistance - Technical Assistance 63O.I8 936.1h - Technical Assistance - Technical Assistance 673.73 6ho.oo - Technical Assistance - Technical Assistance 1,059.59 hh9.2h - Literature Review - Literature Review 823.7U h95.00 $11,128.01 MISCELLANEOUS EXPENSE Laboratory Supplies .................................. X-rays of Experimental Subjects ...................... Food and Expenses Incurred in the Collection of Samples by Experimental Subjects ......................... Proportion of Secretarial, Library, Wash Boys, Shipping Clerks, Draftsman, Animal Caretakers, etc......... Proportion of Heat, Gas, Telephone, Postage, Pensions, Annuities, Maintenance, etc....................... 2,705.77 78.00 2 , 001.00 5,256.38 3,63h.22 I TOTAL $25,00h.l8 API 05081 f 1 - 2- B a l a n c e Femaining from 19^9 .............................. (This includes $1,500.00 received from American petroleum Institute in 19^9 for use in 1950) p e c e i p t s - 1950 .......................... $2U,500.00 Less (for overdraft 19^*0 ( , (for overdraft 19^9 $2,000.00 h,ooo.oo 6,000.00 L e a v i n g for UBe in 1950 ................. ................ Tctal Sum Available for Use in 1950 * .................... Total Expenditures in 1950 ............................... Overdraft of Expenditures over Appropriation 1950 $ 3,^77.98 18,500.00 21,977.96 * 25,00U.l8 3 , 026.20 * An additional sum of $1,000.00 to have been supplied by Universal Oil Products Company, was not paid in through an oversight. ThiB has since been paid (after January 1st, 1951) and is available to reduce the overdraft indicated above. This transaction will appear in the accounts for 1951. API 05082 f I -3- lumlnum Company of America Share of Expense as Itemized ...... ...................... Beceipts 1950 ........................................... $ U,000.00 k,000.PC American Petroleum Institute Share of Expense aB Itemized ........................... Funds Received in 19^9 for Use in 1950 ............. ..... 1,500.00 1,500.00 j, i. duPont deNemours and Company Share of Expense as Itemized ................... ......... Receipts 1950 ............................................ U,000.00 U,000.00 Pennsylvania Salt Manufacturing Company Share of Expense as Itemized ............................. Funds Received for 1 9 ^ Appropriation 2,000.00 Funds Received for 19^9 Appropriation U,000,00 6 , 000.00 Receipts for 1950 .... ............ U,000.00 U,000.00 U,000.00 Permanente Metals Corporation (Kaiser Aluminum and Chemical Corporation) Share of Expense as Itemized ............................. Receipts 1950 ............................................ 2,500.00 2,500.00 Reynolds MetalB Company Share of Expense as Itemized ............................. Receipts 1950 ............................................ U,000.00 U,000.00 Universal Oil Products Company Share of Expense as Itemized ............................. Balance due on 1950 Share of Expense 1,000.CO Total Sum Due ............................................ 1,000.00 1,000.00 API 05083 1 I rommittee on Disposal of Refinery Wastes from W. T. Gunn for - 3/26/51-___________ _____________________________________ _ v c o f i. COPY ------- 211 SOCONY-VACUUM LABORATORIES A Division of Socony-Vacuum Oil Co., Inc. Research and Development Department Paulsboro, New Jersey March 20, 1951 Proposed Study of Fluoride Damage to Vegetation --- Pile: 502153', 11'474'7!>---- Mr. w. T. Gunn American Petroleum Institute 50 West 50th Street New York, N. Y. Dear Sir: As you will recall, at the Cleveland meeting last year, a proposal for partial API support of a research project at BoyceThompson Institute to study fluoride damage to vegetation was pre sented to the Committee on Disposal of Refinery Wastes. At that time, the proposed program was somewhat indefinite. Probably for this reason, and because only part of the petroleum industry has Interests related to the project, the proposal was rejected. During the past year the proposed project has been partially underwritten by other segments of industry and a definite program has been established. We believe that the Information which will be obtained as a result of this project will be valuable in the defense of possible suits against Industry claiming fluoride damage to vegetation. For this reason, we again desire to place before the Committee on the Disposal of Refinery Wastes a proposal for the partial support of this research project. Since not all the petro leum industry is concerned with the problem of fluoride damage, we would suggest consideration of the project on the basis that it be sponsored by API through contributions from only that portion of the petroleum industry operating HF alkylation units. The following information relative to the research project Is presented for the consideration of the Committee: API 05084 ) ? 2 March 20, 1951 organization The Aluminum Company of America initiated the organization f the project. Inquiries were sent to twenty-nine companies, inluding the major smelting and fertilizer companies, several chemical ompanies, and one petroleum company. Of these, thirteen indicated interest in sponsoring the project. At a meeting of the interested companies in February, 1951, the project was discussed in detail and definitely organized. The project will be under the direct super vision of Dr. P. W. Zimmerman of the Boyce-Thompson Institute for Plant Research, Inc., Yonkers, N.Y. A committee consisting of representatives of the sponsoring organizations and companies will review and give general guidance to the project at a yearly meeting. The data obtained will be made directly available to the sponsoring organizations and will be published by Boyce-Thompson as academic research in an appropriate journal. Cost and Financing The program for the project covers a three-year period at an estimated cost of about $30,000 per year. This cost, which is exclusive of the direct supervision and general laboratory facilities supplied by the Boyce-Thompson Institute, is to be shared on a voluntary basis by the sponsoring organizations. tributions pledged (as of 2/ 16/ 5 1 ) are: The yearly con Aluminum Co. of America Kaiser Aluminum and Chemical Corp. Reynolds Metals Co. U.S. Steel Corp. of Delaware Pennsylvania Salt Manufacturing Co. $5,000 5,000 5,000 5,000 1,000 *21,'TOO Other possible contributors are: Tennessee Valley Authority Victor Chemical Works International Minerals and Chemical Tennessee Corporation Coronet Phosphate Company Wilson and Toomer Fertilizer Co. American Smelting and Refining Co. Although the full yearly cost of the project has not been pledged, Boyce-Thompson has been authorized to proceed with the project. The Aluminum Company of America has offered to serve as treasurer for the sponsoring group and will sign the necessary agree ment with Boyce-Thompson, advance the entire yearly amount to BoyceThompson, and collect the individual contributions. API 05085 I Hr. W. T. Gunn - 3 - March 20, 1951 Objectives The objectives of the project, which are described In more detail in the attached "Exhibit A," prepared by Boyce-Thompson, are: , to determine and compare the effects on various plants of long ' time exposure to very low concentrations of HP and short-time exposure to higher concentrations, with humidity as a variable. 2. To determine whether airborne particulate matter containing com * bined fluorine can damage vegetation. 3 . To determine whether the fluorine content e f the soil is a ' factor in damage by airborne fluorine. 4. To develop means for differentiating between damage caused by soil-borne and air-borne fluorine. The general methods and equipment to be used in the pro ject are also discussed briefly in "Exhibit A . " The share of the total cost of the project to be borne by API, if it is decided to sponsor the project, is not fixed, but would be entirely on a voluntary basis. It is our suggestion that the Committee on Disposal of Refinery Wastes consider this proposal only on the basis of its value to the industry, with the thought that the amount of the support would be determined by the willingness of the individual companies to contribute to such support. The above proposal and discussion is submitted at this time with the request that it be placed on the Agenda for considera tion at the Spring Meeting at Tulsa. Respectfully submitted, /s/ H. P. Caldwell HPC:fnc Attach. H. P. Caldwell Member, Committee on Disposal of Refinery Wastes API 05086 1 1 COPY 2.Q.H February 28, 1951 Exhibit A THE EFFECT OF FLUORIDES ON VEGETATION Set forth herewith is a summary of the problems to be considered in connection with the project at Boyce Thompson Insti tute on fluorides in relation to plants. unsolved problems 1 . Effects of fumigating with low concentrations of hydrofluoric acid gas over comparatively long time periods. 2. The effect of low concentrations over long time periods as com pared with higher concentrations for shorter time periods. 3 . The source of the fluorides which accumulate in plant tissue. 4. Variable susceptibility from HF gas in the air after the plants absorb fluorides from the soil. That is, if the plant stores fluoride from the soil, is it more or less susceptible when exposed to HF gas in the air? 5. The maximum capacity of different species of plants to store fluorides after absorption from soil and how this differs when fluoride is absorbed from the air. 6 . The reasons for variable susceptibility of different species of plants. For example, squash is very resistant to HF gas as compared with peach, prune, or gladiolus. 7. Structures of leaves which show characteristic markings to a given gas. For example, HF gas is known to mark leaves at the tip or the edge, whereas SOg gas causes interveinous markings as well as some marking at the edge. API 05087 - 2 Kinds of fluoride compounds which can "be absorbed from the 8. soil. The capacity of plants to absorb fluorides from different 9 soil types. 10. The translocation of fluorides from the point of absorption, for example, by the leaf to different organs of the plant. In a similar way there should be a study of translocation from roots to various organs of the plant. For example, if the source of fluoride is from the soil, would the con tent stored in the roots be greater than that of other organs of the plant, or, stated in another way, if the content in the roots were high, would that indicate that the source of the fluoride is from the soil? 11. The manner in which the plant utilizes, stores, or other wise tolerates fluorides when no evident damage occurs. 12. Similarities between plants which are exposed to fluorides in contaminated air around industry and plants which are intentionally exposed to fluorides by HF gas fumigation. 13. The effects of high and low humidity immediately before and during exposure of plants to HF ga s . 14. The susceptibility of a given species when grown in Washington versus New York. For example, it appears that the Italian prune grown in Washington may be more suscep tible than the same species grown in New York or Utah. Phaa es of the project to be attempted during the first year 1. It is proposed to build six portable greenhouses to be used iu field plots and to limit the species during the first year to a reasonable number that can be handled. For example, API 05088 1 - 3- it is proposed that during the first year ve attempt to study corn, gladiolus, alfalfa, and tomatoes in particular. Fruit trees vill he planted in the field and pruned to have them prepared for greenhouse fumigation during the second and third years of the project. It was suggested that we compare Italian prune, peach, and apple for comparative susceptibility. It appears to he desirable also to make a survey of other garden, ornamental, or crop plants for comparative susceptibility and use the information as a basis for selecting species to be studied during the second and third years. 2. In order to make this a live project throughout the year, fumigating chambers in a greenhouse vill be made available for year-round experimental work. 3. The portable greenhouses will be equipped with blowers and apparatus for supplying a measured amount of HF g as. Attempts vill be made to set up some method for automati cally recording concentration of gas, but it will be necessary at all times to absorb the fluorides from the air and titrate solutions to check the concentration in the greenhouse. Details of these methods vill have to be worked out and will require considerable time in the first year. Tissue analysis at Intervals after exposure of plants to the gas vill constitute a major part of the analytical work during the first year. API 05089 1 5 . Absorption of fluorides from different soil types will be attempted during the first year, and enough information should be gathered to furnish a good basis for experimental work during the second and third years. In this connection we shall attempt to locate good test objects. We are now using buckwheat for that purpose. Perhaps there are better species. Comparison of disease symptoms and soil deficiency symptoms v i t h Inducted damage from HF gas_____________________________ 1 . From a practical standpoint many disease and fertilizer deficiency symptoms are mistaken for HF gas injury. It may be possible to induce certain deficiency symptoms and compare them with HF induced injury. 2. A comparison should be made between susceptibility of well fertilized and poorly fertilized plants. The stage of growth or maturity of a plant in reference to susceptibility needs to be attempted. For example, it is claimed that corn is most susceptible at the roasting-ear stage. The foregoing problems, of course, cannot all be solved during a three-year period. The first year will neces sarily involve a study of methods, obtaining and arranging equip ment, perfecting the overall arrangements so that the problems can be well in hand during the second and third years. It Is hoped, however, that some phases of the work can be completed during the first year. API 05090 1 UNIVERSITY OF CINCINNATI DIPAKTMKNT O f MtCVtNTIVC MEDICINt AND INDUtTIIAL MIALTH U **AT0,T TN* o f M10ICIN-- D M AVENUE N*T. . O'0 June 7, 1951 CABLE AOOBBSS: U T L A ft. CINCINNATI TELEPHONE. CAMT04. U M Mr* D* V. Stroop American Petroleum Institute 50 West 50th Street Nev York City 20 Dear Mr- Stroop: For your information, I am sending you herewith a statement of expenditures made on "behalf of American Petroleum Institute during the first quarter of 1951* I believe this statement will be self-explanatory, hut if you have any questions or comments, Doctor Kehoe would appreciate your bringing them to his attention. Very truly yours, ef I Enc. E. R. Fortlage, ^Secretary to D r . Kehoe API 05091 ^ U N IV E R S IT Y QP CI B CDOCA T I KETTERING LABORATORI ACCOUNT OP. AMERICAN PETROLEUM IN STITU TE por the First Quarter of 1951 oTES (Based on P r o p o r t io n o f Tim e A c t u a l l y Sp en t on P r o je c t ) Sup ervision jobs Ph&ir Jesley Horton " - C o o rd in a tio n o f E x p e rim e n ta l Work Bussell Tye Buth Pierle - Technical A ssistan ce - N N 5rank Cleveland - P a t h o l o g i c a l A s s i s t a n c e Jorothy Templeton- MftTion Duvall - Botert Lampe - Alexander Koncz -- T e ch n ica l N N N A ssistan ce M H H j . Ralph Den^*M * N M I I Carrie Siveley - H jarl Erautle - n n faldo Younlcer - jd Pelta - * N 1.95 1375.02 1759.84 1 0 5 0 .0 0 1 2 0 0 .0 0 133.69 523.62 344.75 1 1 0 .8 8 73.81 498.44 160.45 39.50 155.81 136.08 f/rgT.LAWEOUS EXPENSE purchase o f Anim als Laboratory S u p p lie s Traveling Expense . Proportion o f S e c r e t a r i a l , L ib r a r y , J a n i t o r s , Vab B o ys, Draftsm an, Sh ip p in g C lerics, Anim al C a re ta k e rs, H is to P a t h o l o g i c a l P r e p a r a t i o n e t c . . . . . . . . .' . . . Proportion o f H eat, G as, E l e c t r i c i t y , Steam , Teleph on e, P o sta g e , P e n s io n s , A n n u i t i e s , M a in te n a n c e , A" 1TM * 1 F o o d and S u p p l i e s e t c ................................................ $7563.84 376.60 941.91 897.68 TOTAL Balance Remaining for Further Vork In 1951 at End of 195 . . . . . . .................. $51,4 6 7 .0 3 Receipts - January 12, 1951 ........ Expenditures - 1st Quarter 1951 . . . . . . . . . 9,065.12 $5&i53r.l5 21,061.29 balance Available for Further Work in 1951 at End of 1st Quarter 1951... * ............ 39,470.86 $21,061.29 API 05092 I J m m 12, 1951 B r. N. I . B a v q slst, Chalrana 8alinn-- It t -- aa CareInon lo lt j c/o Tto Texas Conpanj 135 t o t %2od S tre e t Bea Torte 17 to v Torti V Dm t Dootor Bw fp lr t t Ter j -- r In fo rn a ti-- a n i f ila * t n n la anelo -- A 0097 off la tta r AateA Jwm 7 , 1951 v lth attaetod atata--n t r f espandita ra * -- Aa tgr C a tta r li* Latoratorp -- Wtolf c f tto A--rio -- Petrola-- In s t itata d a rla* tto r a t f --r t a r a f 1951. Try trm ly jo n rs. ! BVS:o ce: B r. B . B . tosa* API 05093 ICOTtt uetosict or c o c u u n D epartm ent o f P re v e n tiv e to d lc ln s and In d u s tr ia l H e a lth jit t e r in g la b o ra to ry r o lle s s o f M*41c in * " 2 d an 19, Oblo venue Jtoe 7, 1951 M r. D . 7 . Stroo p Am s r l c a a P e tr o le u m I n s t i t u t e 50 t o s t 5 0 th S tr e e t le v fo r k C ity 20 Sear M r. S tro o p : ? o r y o u r in fo r m a t io n , I sm s e n d in g y o u h e r e w ith a sta te m e n t o f e x p e n d itu r e s made o n b e h a lf o f A a s r lo a n P e tro le u m I n s t it u t e d u rin g th e f i r s t q u a rte r o f 1 9 5 1 . I b e lie v e t h is sta te m en t w ill be s e lf-e x p la n a to r y , b u t i f you h are an y q u e stio n s o r c a o n e n ts , D o c to r Z eh oe w o u ld a p p r e c ia te y o u r b r in g in g th a n to h is a tte n tio n . ery tr u ly you re, /a/ X . B . F o r tla g e X . H . P o r tla g e , S e c re ta ry to & r. Xehoe f i API 05094 ' dutiesin ar cacaiATi D i m a LABCBAZOBT ACCODI! OP ARPICAI PgTOOIZDM IETITPTg For the P in t Quarter o f 1931 in s c i* H e y r o th - S u p e r v la lo a jo b s F b a lr - V e s le y lo a r to n - C o o r d in a tio n o f K x p e r la s n t a l B u s s e ll T P - T e c h n ic a l A a a la ta n c e B u th P ls r le - jr a n k C le v e la n d - P a t h o lo g ic a l A s s is t a n c e D o ro th y T s s p le to n - M a r lo n C a v a li - B o b ert L ssp a - A le x a n d e r K o n e z - B a lp h D e n h a a - C a r r ie S lv e la y - f a r i E r a s t le - V a ld o T o o n k s r - Id P e lt a - T e c h n ic a l ss 1 91 n m 99 A a a la ta n c e 9 I 99 9 N W ork iggciLLAgODS SXFBKE Purehaae of Aalaali ........................... Laboratory Suppliea ............................ Traveling IsptoM ............................ Proportion of S e c re ta ria l, L ib ra ry , Ja n ito rs, Vaah Boya, D raftasan, Shipping C la rk s, A n lsal C a rsta k srs, K lato Pathological P reparation, a te ............................. Proportion of H aat, Oaa, E le c t r ic it y , 8tean, Talaphoaa, Postage, Pensions, Am m ltiee, Malntananoa, A n lsal Ioo4 and Su p p lies, e tc ..................................................................... .. 1.95 1,375.02 1,759.8b 1,050.00 1,200.00 133-69 523.62 3bb.75 110.88 73.81 b98.bb I60.b5 39.50 155.ai 136.08 $ 7,563.8b 376.60 9 b l.9 1 897*68 7> bll.87 3,869.39 TOTAL................................... Balance Regaining fo r Farth er Work in 1951 at End of 1950 ................................................................... 651,^67.03 Receipts - Janaary 12, 1951 ............................................... 9.063.12 *0 ,5 3 2 .1 5 Xzpendltarea 1 st Barter 1991 ....................................... 1,061.29 Balance Available for Farther Work in 1951 at End of 1st Quarter 1951 ................ 639,^70.86 $21,061.29 API 05095 * Jons Xk 9}1 fir* Bobart A* Kshos TBdoarsltf of Cincinnati tettarli Labaratory ef Affilai Fhyalology Cincinnati 19 Obl Baar Deeter tehoe: Z bava Jwmt rariaaad joar lattar af Ayrll 2 19% sai tte alaataa of tte Ihlrtaratk Nm U af tte Institata*a Mailaal Adrlaory CcMlttss, bnt Z io aot eons to aj iefialta conclusi as to te statar af tte flaorlaa irTsatigatioa. is yon knov oar raaaarab baigsta bava basa fissai vfoc a fiscal ysar basir it tte fatar baglnalttf ftlf 1. At jrsasat aa te tei-- tal far tte flaaal faor 19%% te asm af $2,^00 sa a sontribntlon to tte flnorias laiaatl-- tlon, tet pspnsat ls oontlngsnt pon eontlanatlon of eooparatlTs ork bj tte otter industriai particifasta and upoa tte condtlon ttet tte API sbara of eost steli aot exoaod 2^ par cast of tte total eoat darlag tte porr* Zt vili ba apfroelstod If poa ili gito n sufflelast infornatlon to Jastlfy a ioeislon abomt thls aattor. Ysrjr fcrulgr jroura, BV&ts osi Ir. 1 1. Bsota P.8. to Boetor Basto! Z ondar if jmt sboali apyolat n mw far tte SnbooMdttoa on P lssrld a s to aneoooi Bostor loag ho la no lon--r a naabsr of tte teiloal Adolsory Canaltta a t BIS API 05096 i I 14# 1991 Br. B. 1. Imh I M M O U Coaptagr (latita) 910 Botta B i k i p i m m M ef Mat: k m ai API 05097 k \ Copy from M. N. Nevquist for information of Members of Subcommittee on Carcinogenicity. _______________________________________6-19-51 AMERICAN LOCOMOTIVE EXPORT COMPANY, INC. New York, U. S. A. 25 Victoria Street London SW 1 11th June, 1951* Ur. M. N. Nevquist, M. D., The Texas Company 1 3 5 East 42nd Street jiev York 17, New York ' pear Dr. Nevquist, Thank you for your letter of May 11th just received enclosing two copies of the "Report of Progress in the Appraisal of the Potential Carcinogenic Properties of American Petroleum Products". I am circulating one of these copies to the Members of the Institute of Petroleum Research Council "Committee on Carcinogenic Action of Mineral Oils" by whom it will be circulated to Members. We are all anxious to ensure that the valuable information emanating from the A.P.I. ex the Kettering Laboratories should be used here to the best possible advantage and for that reason would be grateful if you could send us six copies of each of these reports as they are produced. You will understand how important ` it is that the individual workers at the Universities .and other ' Research Laboratories dealing with different aspects of this problem should be able to refer to their own copies. This'is also the case with the oil technologists engaged on the choice of material and its fractionation. In order to avoid any possible lapse in this exchange of official documents they should continue to be sent to me at the Institute of Petroleum. At the same time it is highly desirable that on purely technical matters there should be the fullest ex change of knowledge, through direct correspondence, between the individuals concerned in the U.S.A., and the U.K. There will therefore, we hope, be increasing correspondence between the Medical Research Council and Dr. Kehoe and between the individual chemists and medical men concerned and their opposite numbers. This however will leave the main arrangement unaltered for the ex change of official documents between the A.P.I., and the Institute of Petroleum. I API 05098 * 2 - I am looking forward to meeting Dr. Phair personally, and having a discussion on the various aspects of our joint Problem. I have already been in telephonic touch with him. During the recent Petroleum Congress at The Hague I also had the opportunity of discussing oil carcinogenicity with Dr. Mackenzie 0f your Company and shall take the opportunity of inviting him to one of the I.P. Research Group Meetings. Please accept my best thanks for your collaboration and 0v assurance that every endeavour will be made to keep you in the fullest touch with the work which is being done over here. Believe me, Yours sincerely, (signed) S.J.M. Auld S.J.M. Auld SJMA/GBM API 05099 API 05100 Pi ' , u w m i c f f AMERICAN LOCOMOTIVE EXPORT COMPANY, INC. NEW YORK, .S.A. 25 Victoria Street London SV 1 K, N. Newquist, ** Texas Company, 5a York w17 / ?* " M.D., 11th June, 1951* P'gr Dr. Newquist, Thank you for your letter of May 11th juat received closing two coplea of the "Report of Progreaa in the Appraiaal the Potential Carcinogenic Propertied of American Petroleum products". I am circulating one of theae coplea to the Membera Iftie Institute of Petroleum Reaearch Council "Committee on Carcinogenic Action of Mineral Olla" by whom it will be circulated to Membera. We are all anxious to enaure that the valuable information aanatlng from the A.P.I. ex the Kettering Laboratoriea should be used here to the best possible advantage and for that reason would be grateful if you could send us six copies of each of theae reports as they are produced. You will understand how important it is that the individual workers at the Universities and other Research Laboratories dealing with different aspeota of this problem should be able to refer to their own copies. This is also the case with the oil technologists engaged on the choice of asterial and its fractionation. > In order to avoid any possible lapse in this exchange of ; official documents they should continue to be sent to me at the Institute of Petroleum. At the same time it is highly desirable that on purely technical matters there should be the fullest exchange of knowledge, through direct correspondence, between the individuals concerned in the U.S.A., and the U.K. There will therefore, we bops, be increasing correspondence between the Medical Research Council and Dr. Kehoe and between the individual chemists and "*^eal men concerned and their opposite numbers. This however 1#ave the main arrangement unaltered for the exchange of official documents between the A.P.I., and the Institute of Petroleum. 1 . I am looking forward to meeting Dr. Phair personally, and 2 Tln8 * discussion on the various aspects of our joint problem. "*** already been in telep h on ic touch w ith him . During the recen t API 05I0I # * pr M. N. Kewqulst, M. D. June 11, 1951 petroleum Congress at The Hague I also had the opportunity of discussing oil carcinogenicity with Dr. Mackenzie of your Company and shall take the opportunity of inviting him to one of the I.P. Research Group Meetings. Please accept my best thanks for your collaboration and my assurance that every endeavour will be made to keep you in the fullest tough with the work which is being done over here. Believe me, Yours sincerely, (signed) S.J.M. Auld S.J.M. Auld. sjma/g b m . API 05102 I A m e r ic a n P e t r o le u m I n st it u t e SO W EST BOTH STR EET NEW YORK 20. N. Y. . N T o f TECHNICAL V I C E * t r o o p . D.RECTOR June 25, 1951 Board of Directors UniTersity of Cincinnati Cincinnati 19, Ohio Gentlemen: This communication is authority to continue -work on Investigation of the toxicity and mode of action of certain petroleum products for the year ending June 30, 1952, according to the terms of the agreement dated January 8, 19^6, and on the basis of a maximum budget far operating expenses of $100,000. e Upon receipt of your approval of the continuation of the project with this imrriunnr budget we shall pay you the sum of $50,000. The balance of $50,000, less the unexpended balance in the fund on June 30, 1951, will be paid on January 1, 1952. It is understood that any balance remaining in the fund on June 30, 1952 will be returned to the American Petroleum Institute, and that no excess over the amount of the budget is to be obligated or spent without written authorization. Very truly yours, * AMERICAN PETROLEUM INSTITUTE Accepted and Approved UNIVERSITY OF CINCINNATI Throt^ its Boarc^of Directors By ^ \ - t . __ ChairmalT, Board of Directors By Clerk, Board of Directors API 05104 r f ( I Ananry 10, 1951 Br. Bbert A. bkoi uairereltor of Cincinnati The Eetterlng Iabarmtorjr College of Medlelne - Eden Avenue Ciaclomtl 19, Ohio Beer Doctor lehne: Psraaut to oor cootlaaatloa eoatrect vlth the Unlveralty of Claclnaetl, ue ehoeld hr* amt oor eeeoad flaoal j m t Budget pejaent ob Jeaaury 1, 1951; bornrer, joor flaulei etateaente ooea to lndloete e eabetaatlal unoxpondod Balance oa depoelt et the Ualrerelty. In eoncrrtaire vlth the jrarlalaoe of the eeoocd paragraph et the oontreet, ue enoloeo the Inetltate'e check la the a w r t of $9,065.12 vfaich p pu eat the Alfferenee totalen $50,000 and the unexpcnded balaane of $J*0,93^*88, ea reported et the ead of the eeeoad Quarter, June 30, 1950. Thle check coapletee the payaenta dae ander the preee&t contrect for the jeer endlng Jane 30, 1951 ery truly joure, DVS:e c e : I r . B . 1 . B eere M r. L a c e y W eih er lote to Mr. Welker: Ihle dlehureenent le to he eherged egelnet the epeclel Medloel A&vlncry Tand. STB API 05105 J ) ) ti-- T 10, 1991 t STB ta lo t* to Mr. W alkart Thla dlaVoraoarat la to Wo okargad ag alaat tka ap o d al Madloal A dvisory Fvad* 9TB API 05106 <fr r t * i | ,s l a b o r a t o r y / 0 r m edicin e-- eden aven ue ^,,R A T I OHIO UNIVERSITY OF CINCINNATI departm ent o f preven tive m ed icin e and in d u st r ia l health July 26, 195- ~u. V CASLC ADDRESS: KETLAS. CINCINNATI TELEPHONE: CAMTOL M M Kr. D. 7. Stroop, American Petroleum Instv _ L vi 6 f 50 Vest 50th Street, New York City 20. Dear M r . Stroop ' - v-e-^evith acknowledge with thanks receipt, of American Petroleum institute's check in the amount of $5 0 ,000.00, covering expendi tures to be made on their behalf during the period July 1, 195'- to June 1951* Very truly yours, E. R. Fortl&ge, Secretary to D r . Kehoe<^ ef API 05107 T I a u s i , 1930 S r. iB k r t K, f e l-- e lty o f eiMiMtt C o llo o f rniimim C lo n i-- t l 19, tod fely 18, oaA tko 1950-31 f***l or, H $30,000 111 of C *o kook tt 1 tto of tory truly your, DVB: eos t e . H e ito r D arlo lo fe to Mr. fe lk a rt f e l l i M o d in i A drleary lo to to API 05108 r SS " " " > i UNIVERSITY OF CINCINNATI d epartm ent o f p r ev en t iv e m ed ic in e and in d u st r ia l h ea lth July 13, 1S50 C A B U ADDRESS KETLAR. CINCINNATI TELEPHONE: CAPITOL 1414 Mr. D. V. Stroop, :jnerican Petroleum Institute, 53 Vest 50th Street, New York City 20. year Mr. Stroop : ' return to you herewith, according to the request in your letter of July 6, two copies of the signed agreement. I have noted the comments on the application of a certain portion of the funds to graduate education for the one year only. I'll he clad to discuss this matter subsequently with all concerned. I think the point of it has been missed by some of the members. Cordially yours, F.AE ei ;nc . lictated but not read. r. Robert AT ehdeL> M . D API 05109 O F THE PRESIDENT srf'c i ; A merican P etroleum Institute SO W EST SO th STR EET NEW YORK 20. N. Y. M U 1, 1950 Boari of Directora UniTarsity of Cincinnati Cincinnati 19, Otalo Itale eoanaodcatlar In sn th e rlty to onatlnaa verta on in ra stlg a tlo a of ttaa tcn d elty a n i noia o f actio n o f e a rta la p e tro le u jrodnota fa r ttaa ja a r andine M m 30, 1951, aceariln g to ttaa ta n a o f ttaa agreanMKt d a ta i imammrj 8 , 19$6 , and on ttaa beala o f a a c ri-- tardeet fa r oparetlng npaaaaa o f $100,000 atleta la eoadltlanad npaa a a la i-- naaTjianiail baiarne of $8,000 i-- Inln la ttaa f u i a t ttaa U n irrro lty a f C in cin n a ti aa of Zana 30, 1950 a n i Ritta ttaa s a iarata a i ta f ttaat a p o rtlo a, not to e s s a i 10 par eanct, f ttaa tanieat ataall taa aTpaadatala la arypart a f ttaa Bnl Y ir a ltys p rn p w o f gradnata tra in in g in la d n a trla l n ad leln a. Upea raoalpt of jonr approval of ttaa eeatlnaatlaa ani expanalen of ttaa project ritta ttala onditianal u t Iu b tardent va ataall pay yen ttaa ana af $50,000, ttan taalanee of $50,000, laaa ttaa empandad balana of $8,000 or nera aa of fana 30, 1950, to ba pali an Jauarj 1, 1951. It la vadaratood ttaat any balana roanialng In ttaa fond on Jone 30, 1951 LU taa ratarnad to ttaa Aaarlean Tetrolsrn Institute, and ttaat no aseas orar ttaa avrai af ttaa tardent la to ba obliente! or apaat rlttaort arittan aathorisatloa. Tary traly yerra, Acaaptad and Approrad U liU H U R or C] Ita of Directora Chairman, Board of I>lrectors r Clerk, Board of Directors API 05110 > A merican P etroleum Institute SO W EST SOTH STR EET NEW YORK 20. N. Y. _ . T Of TECH N ICAL B E V IC E P ^ V v I D V. ST E OOP. D.MCTO June 29, 1951 Dr. Robert A. Kehoe University of Cincinnati Kettering laboratory of Applied Physiology Cincinnati 19, Ohio Dear Doctor Kehoe: * Please accept my thanks for your letter of June 16 which served to clarify my understanding of the current status of the fluorine investigation. Enclosed is a check in the amount of $2,,500 to cover the Institute's contribution for the fiscal year ending June 30, 1952. Very truly yours DVS:c Enclosure cc: me: D r . B . B . Reeve Dr. Geo. M. Saunders Mr. Lacey Walker Members and Associates, Subcommittee on Fluorides API 05111 r COPY P UNIVERSITY OF CINCINNATI Department of Preventive Medicine and Industriad Health Tbe Kettering Laboratory College of Medicine - Eden Avenue Cincinnati 19, Ohio June 16, 1951 Mr. L. V. Stroop American Petroleum Institute 50 Vest 50th Street New York City 20 Dear Mr. Stroop: I am sorry that my letter of April 2 was not clear to you. Evidently, the third paragraph, including the table of pledged funds, was not regarded as guaranteed. I can assure you that these funds are available for the further prosecution of the work in 1951- As to 1952, the least sum that will be available on the basis of present commitment is $17,000.00 exclusive of API funds. It is probable, although not a matter of firm agreement, that all of the sponsors will continue to be represented on the same basis in 1952. It is apparent, therefore, that the two contingentconditions, i.e. (l) of the continuation of other sponsors, and (2) of the assurance that the API contribution will not exceed 25 per cent of the total co6t during the year, are assured for the fiscal year 1951-52, of API. II I trust that this covers the situation, but if I have failed to understand your query, please do not hesitate to restate it. With kindest regards, Cordially yours, RAK ef cc: Dr. B. B. Reeve /b/ Robert A. Kehoe Robert A. Kehoe, M.D. API 05112 (C o P Y) / A merican P etroleum In stitute SO WEST S O t h STREET NEW YORK 20, N. Y. tm en t 0 F TECH N ICAL v ic e s DAVID V T R O O P . DIRECTOR June lL, 19 51 Dr. Robert A. Kehoe University of Cincinnati Kettering Laboratory of Applied Physiology Cincinnati 19. Ohio Dear Doctor Kehoe: I have Just reviewed your letter of April 2, 1951 and the minutes of the Thirteenth Meeting of the Institute's Medical Advisory Committee, but I do not come to any definite conclusion as to the status of the fluorine investigation. As you know our research budgets have been placed upon a fiscal year basis with the year beginning July 1. At present we have budgeted for the fiscal year 1951-52 the sum of $2.500 as a contribution to the fluorine investigation, but payment is contingent upon continuation of cooperative work by the other industrial participants and upon th? condition that the API share of cost shall not exceed 25 per cent of the total cost during the year. It will be appreciated if you will give me sufficient information to Justify a decision about this matter. Very truly yours, BVS :c cc: Dr. B. B. Reeve /s/ D. V. Stroop API 05113 . arrutLATO.ATOOT ^ o f HID IC IN O -U a A VU U E iMaati M". oomm,, UNIVERSITY OF CINCINNATI MftumwtT or ru w m v E m w am aid wmimiAL i J u l y 2, 1951 HIj.. r. V- S t r o o p American P e t r o l e u m I n s t i t u t e 50 V e s t 5 3 t h S t r e e t Nev Yor k City 20 Dear M r . Stroop : I herevith acknowledge with thanks receipt of American Petroleum Institute's check in the amount of $2500.00, covering expenditures to he m a d e on t h e i r b e h a l f in the i n v e s t i g a t i o n of f l u o r i n e f r o m July 1, 1951 to Ju n e J > 0 , 1952* Very truly yours, ef API 05114 UNIVERSITY OF CINCINNATI DEPARTMENT or P U Y E N T IV I MEDICINE AMO IN DUETUAL HEALTH HE lANONATOMT IOICIM E-- EOBM AVEMOE July 1 , 1951 M,,. t). v . t r o o p Department of Technical Services ynrican Petroleum Institute cq West 50th Street jjev Y o r k C i t y 20 Dear Mr* Stroop: T am forwarding to you herewith two copies of the of a g r e e m e n t b e t w e e n A m e r i c a n P e t r o l e u m I n s t i t u t e of C i n c i n n a t i to J u n e 30, 1952* executed extension and the University Very truly yours E . R . Fo r t l a g e , S e c r e t a r y to Dr. Kehoe Enc. API 05115 t Mjr IO, 1991 iv. Botar* . afta OBiwalty of Cinainnati rum KattarlaB Ubanti/ reiin# of Nndlalaa - U hi Av m m Cine in n a ti 19, Ohio Dur Xtoetar Ita Thia U *o aakaenlofo wiript of jroar lottar atta JAly 3# 19 ta tka tv aayioa of tka ilcoi taTMHoat far 1951-52 fi-- al j*ar. tool-- jaa SUI fiat tka Znatltato* taek w i U o to tka tal-- valf f Mvlaatt la tka -- nont of $50,000 pwoaant u tka tana f tka lary traly yonra, m i Ir* ! 1* Booi a Boto to ltr. altari Stia oxpanAltnra la to ta etarsai afaiaat tka NaAleal Aiolaavy Ini. P Ia Jjsts-kJ API 05116 ^ jhouoomtow K**0*"BIDICIMI--CBU AVENUE ttl o # UNIVERSITY OF CINCINNATI w u n a r or peeventive h u ic in i and indueteul health July 15, 1951 Mr. D. V. Stroop, Director Department of Technical Services American Petroleum Institute 50 West 50th Street . He* York City 50 pear M r . Stroop : I herevith acknowledge with thanks receipt of American Petroleum Institute's check in the amount of $5 0 ,000.00, covering expenditures to be made on their behalf. Very truly yours E. R. Fortlage, Se/cretary to D r . Kehoe . 1 ef API 05117