Document RpgvaDKvpEGMOnNV42dMoLr38

UnitCode 8308 1/14/99 2:54PM UROBILINOGEN, 48-HOUR, FECES ,SeneraIlnformaton FEE: $122.70 LABORATORY AREA: Porphydn-32/HC25 ANALYTIC TIME: I day DAY(S) TEST SET UP: Monday throughSaturday TIME OF DAY: Continuously LABORATORY HOURS: MAXIMUM LAB TIME: 3 days COMMENTS AND OTHER REJECTION: -cv 6%. -ifthawed butcold,notetolaboratory. -ifRANDOM SAMPLE Isrecd, REJECT. Ifcj!enItnsistosn tesdng: 1.ConsultatiownithDr.McConnell must occurbeforelabwillaccept specimen and performtheassay, 2.We have NO NORMALS fora RANDOM specimen, 3.IftestIsrun,thereportwillbe as grams ofspecimen. --Shouldbe a 24,48 or72 hour collection, Lab willNOT do on anythingotherthantheabove listetdimed colledons. -Pleasedo notcalltheroutnelaboratorfyorapprovalofspecimen not meetingcollectiodnurationedto(te. SPECIMEN RETENTION TIME: Untilreported LAB CONSULTANT TO CONTACT Ist: Dr.McConnell 4-7437 LAB CONSULTANT TO CONTACT 2nd: LAB CONSULTANT M CONTACT 3rd: CLINICAL CONSULTANT, CLINICAL SERVICE: TECH M CONTACT lst: Paul Ch&ick 4-8081 TECH M CONTACT 2nd: Chuck Kroll4-3232 LABORATORY: Porphyrins4-3232 2'd S13b"l-WIC34 Okbl4WJOP:EO 66,, PT WUr UnitCode 8308 1/14/99 2:56PM UROBILINOGEN, 4"OUR, FECES '4ethodand Reference METHODOLOGY: Colodmetfic METHOD: Urobiliinnthefecesisreduced to urobilinogebny treatmentwith alkalinfeerroushydmxide. The urobilinogeinsthenallowedto react withEhrlich'rseagenttoform a redcolorwhich can be measured spectrophotomstdcally. E'd S8brl-tOIa34 OKUW WDOP:EO 66, 'PI NUf UnitCode $308 1/14/99 2,-56PM UROBILINOGEN, 443@-HOUR,FECES linir.Ianlformation CLINICAL INFORMATIO N: -Urobilinogenconsistsofthecolooessend productsofbillrubin metabolism which areoxidizedby intestinmailcroorganismstobrown pigments(ste=bllin). -Normally,fecalurobilinogeanppmximates thetotalexcretionof bliepigments(thebreakdown productsofhome). USEFUL FOR -DiagnosisofdisordersInvolvinhgemolysisand hepaticobstructive conditions INTERPRETATION - Increaseddeswcdon ofredbloodcous,such as inhemo"C anemia,increasesthe amount ofumbilinogenex=ted. - Liverdiseasesingenerallessentheflowofbillrubtionthe intestinaend thusdecreasefecalexcretionofumbignogen. - Complete obstructioonfthebileductredum theumbilinogenof thefecestoverylow levels.Clay-colorefdecesInobstrucuve jaundiceresultfsrom theexclusionofbilepigmentsftm the intestine. -Oraladministrationfb=d-spectrum antibiotidcisminishes conversionofthebillrubtionurobilinogeinntheintestines. CAUTIONS - Informatioanboutoralbroadspectrumantibiotitcaskenrecentlbyy the patientmust be accurate.Oralbroad spectrum antibiotics decreaseurobilinogemneasurements by diminishinbgacterial conversionofbilirubtionumbilinogeninthefem, leadingto falsellyow values. IMMEDIATE fixatioonfspecimen by theprescribedpreservativ(esodium carbonate/petroleuomther)inan opaque containerisessentials,ince urobilinogeinslighstensitiveP,oorfixatiognivesa falsellyow reading. REFERENCE - Schwartz S, Sborov V. Watson CJ- Studiesofumbilinogen: quantitativdeeterminatioonfurobilinogebny means oftheEvelyn photoelectrcioclorimaterA.m J ClinPathl14:598-604,1990 17'd -RIOIT3W OATIW WDOP:EO 66, NUr