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Industrial Hygiene Digest
April, 19
experiment, arrangement, and the analysis. The results show that the active ingredient
is absorbed by the plant neither through the leaves nor the roots. Animals that take in
the active ingredient, perhaps during harvesting time as residue on green (odder, very
rapidly excrete it almost completely with the ding. Small amounts which are absorbed
are.partly discharged in the urine, partly distributed over the whole body, broken down,
and within a few weeks also excreted. A graphical analysis of the excretion curves shows
that the active ingredient leaves the body with a biological half life of 20 hours while its
metabolic products have a biological half life of 8 or 70 days, the latter being attributed
to inorganically bound tin.
-- Nuclear Sci. Absts.
359 Effect of Zirconium Citrate on Early Femur Uptake and Urinary Excretion of Radioisotopes.
B. Kawin. Health Phys._9_, 1031.1034 (Nov. 1963).
'
Effects of single intraperitoneal administration of non-radioactive zirconium
citrate on femur uptake and urinary excretion of either simultaneously injected intravenous
Ce-144, Pu-239 (VI) or Y-90 were compared in rats during the initial post.injection hour.
Zirconium treatment was associated with increased plasma disappearance of Pu.239.
Comparisons in control and treated animals indicate that zirconium citrate treatment
has no effect to alter rates of femur deposition for the early time interval studied, and
that it enhances urinary excretion of Ce.144 and Y.90, with only a very small effect on
Pu-239 excretion.
.. Nuclear Sci. Absts.
360 The Work of an Occupational Hygiene Service in Environmental Control. R.l. McCallum.
Ann. Occ. Hyg. (London) 6, 55-64 (April June, 19<>3).
Industrial hygiene services which deal with industry as a whole face difficulties
arising from widely varied industries, their geographical position, and the different outlooks
of individual firms. The work of the North of England Industrial Health Advisory Service
is briefly described. Among other problems, it is at present concerned with lead absorption
and poisoning in burners in the shipbreaking industry, and skin irritation and pneumoconiosis
in antimony process workers. Studies were made in which the data indicated an excessive
amount of lead to be present in shipbreaking yards. There are between 20 and 24 such yards
scattered around the coast of Britain, employing between 6 and 60 burners each. Burning
through steel plate and girders with oxyacetylene torches was introduced in 1918 as a method
of reducing the size of metal pieces as naval vessels were scrapped. The method is currently
the same except that the fuel may now be propane or coal gas. The high temperature of the
flame vaporizes the lead in the paint work. Air samples taken at 2 shipbreaking yards showed
the levels of lead to be considerably above the maximum allowable concentration of 0.2 mg/
cu.m even in the open yard where conditions were such that one would expect good natural
ventilation. Samples taken during the breaking up of a tanker show that there may be little
difference between the amount of lead in air when burning is done aboard ship (1.54.-- 1.72
mg. /cu. m.) as compared with the open yard (1.15--2.16 mg/cu.m.) and that there was an
excessive amount of lead in the air of tne yard as a whole~and that it often persisted for some
time after work had ceased.
APCA Absts.
361 Environmental Factors in Childhood Lead Poisoning. R.C. Griggs, et al. J. Am. Med. Assn. 187, 703-707 (March 7, 1964).
In a series of 906 children contacted by door-to-door survey, information was
obtained on pica and environmental factors related to lead poisoning, and urine samples were
analyzed. Urine was abnormal for lead and coproporphyrin in 216 of 801 children living in
old housing and in 3 of 105 children of similar socio-economic background living in a new
housing project. Thirty.eight children from old housing, but none from new housing, had
significant evidence of lead intoxication. A history of pica for paint, dirt or plaster was
obtained more frequently in the old housing but was not an adequate screening test for lead
intoxication. Flaking paint on the inside of the home was the environmental factor most
frequently associated with an abnormal urine.
-- Authors' abst.
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