Document RjM1e2eOzre6a8o1axg4y3vg7

S0153614 ** * THIS IS AN OFF-LINE BIBLIOGRAPHIC CITATION LIST GENERATED BY ** * MEDLARS II * * N.L.M.'S NATIONAL INTERACTIVE RETRIEVAL SERVICE * * ** **.**********************#******************* VBWL CHUUU GlSiAS* NUMBER OF CITATIONS PRINTED =3 ^ THIS SEARCH HAS PERFORMED ON THE SORT MAS NOT REQUESTED REQUESTED BY RNW JULY 11. 1981 FILE. PLEASE SEND THIS LISTING TO 3- SHIRLEY 0. CONNER UNION CARBIDE CORP. PO BOX 8361 SOUTH CHARLESTON. MV 25303 ucc 020662 S0153614 x*xxxxxxx#*x#*xxxx*xxx#xxxxxxxxx*#xxxx#xxxxxxxx*xx'*xxxxxxxxxxx#x#*x##*## ** x THIS IS AN OFF-LINE BIBLIOGRAPHIC CITATION LIST GENERATED BY ** * MEDLARS II x * * x N.L.M.'S NATIONAL INTERACTIVE RETRIEVAL SERVICE X * XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXXX VINYL CMtOHXM DtSKAM^ NUMBER OF CITATIONS PRINTED = 3 THIS SEARCH WAS PERFORMED ON THE T0NM8K7| SORT HAS NOT REQUESTED REQUESTED BY RNH JULY 11, 1981 FILE. PLEASE SEND THIS LISTING TO SHIRLEY D. CONNER UNION CARBIDE CORP. PO BOX 8381 SOUTH CHARLESTON. MV 25303 ucc 020663 00023167 VINYL CHLORIDE DISEASE PAGE 1 1 SI AU AO TI SO AB KW KW KW RN ^EM SI fAU TI SO - IPA/77/00383 - Ward AH > Udnoon S i Watkins J ; Walker AE > Dark* CS - Protein Reference Oiit, Dept. of Immunology, Hallemshir* Hoipi tai Medical School) Sheffield S10 2RX, England - Immunological mechanisms in tha pathoganssis of vinyl chloride!) d1s*a*% - Br. Mad. J.J VOL 1 ISS Apr 17 1976. P936-938. (REF 23) - IPA COPYRIGHT: ASHP Immunological invasligations war* performed on 58 workers from a vinyl chloride polymerization plant and the results explain the pathogenic mechanisms of vinyl chloride disease and allow some conclusions to be drawn about its etiology. Vinyl chloride disease is a multisystem disorder incorporating Raynaud's phenomenon) acro-osteolysis, thrombocytopenia, portal fibrosis, and hepatic and pulmonary dysfunction. Immunological and immunochemical investigations showed the presence of circulating Immune complexes in 19 out of 28 patients with the disease and in a further 2 out of 30 workers exposed to vinyl chloride. The Immunological data were reviewed in relation to the clinical picture of the disease and to the available evidence on the metabolism of vinyl chloride. The results suggest that vinyl chloride disease is an Immune complex disorder and that the Immune response Is initiated by tha adsorption of vinyl chloride or a metabolite on to tissue or plasma protein. - Vinyl chloride toxicity, environmental - Toxicity, environmental vinyl chloride - Mechanism of action vinyl chloride - 75-01-9 - 7707 - TOXBIB/77/02 7965 - Friedel HP - (The so-called tfllMPiUm I* .jt lflpii Germany! the Federal Republic of - Fortschr Mad! VOL 99, ISS 26, 1976, P1916-9 IS - 0015-8178 AB - A short outline is given of the historical development of the so-called vinyl chloride disease in the Federal Republic of Germany. It Is a report on the measures taken--including the research work. Latest statistics about the cases of occupational disease are shown. KH - TOXBIB i Chemical Industry "/STANDARDS l English Abstract KH - Environmental Exposure i Germany, West i Human KH - Industrial Medicine STAM1ARDS ; Maximum Permissible Exposure Level KH - Occupational Diseases "CHEMICALLY INDUCED KM - Vinyl Chloride "POISONING ; Vinyl Compounds "POISONING EH - 7707 00023166 VINYL CHLORIDE DISEASE PAGE 2 3 SI - TOXBIB/75/167545 AU - Kind R ; Hornstain OP TI - [Acro-osteolysis (acro-oateopathta ulcero-mutiIans) In a worker exposed to vapours of aynthatica (author's tranil)] SO - Otach Mad MochenachrJ VOL 100, ISS 16, 1975, P1001-4, 1007 LA - Ger CD - DMWOA IS - 0012-0472 AB - Tha neuro-cutanao-osseous syndrome of "apopadie" aeroataolyaia (of Buraau-Barri ere), localized to tha anda of tha faat, hat occatlonally baan aaan In workers engaged In tha polymerization of vinyl ehlorida, A caaa of tha diaaaaa la daaenbad In a 42-yaar-old worker axpoaad to diffarant vapours during tha manufactura of plaitic producta, but ha had navar worked with vinvl ehlorida. Outatanding aigna uera dyiprotamaamia, moderate thrombocytopenia, uhtla symptoms of Raynaud'a diaaaaa aa wall as aclarodarma-lika changat in hands and fast (typica > were absent, Tha onset of tha oa as corraapondad to prolongad axpoaura to cold on tha job. It la, tharafora, assumed that thara was concaalad chronic intoxication with synthetic vapours which, in connection with cold exposure and other individual factors, may have aided in the manifestation of tha disease. It is possible that under certain conditions synthetics other than vinyl ehlorida may contribute to tha occurrence of sporadic cases of aero-osteolysis. KM - T0XBIB ; Adult i Blood Protein Disorders COMPLICATIONS KM - Casa Report ; Chronic Disease ! Cold i English Abstract KM - Foot Dermatoses "CHEMICALLY INDUCED/COMPLICATIONS ; Human KM - Plastics i Skin Ulcer "CHEMICALLY INDUCED/COMPLICATIONS ; Syndrome KM - Thrombopenia COMPLICATIONS EM - 7512 "* END OF OFFLINE PRINT *""** ucc 020665