Document Razz2n6oGvX8JaKgY1epYa0vv

March 3, 1986 H. W. Dietz Subject: Toxicology Activity Report - February, 1986 1 .D^T^sl sted the FPD in preparing a preliminary information package for submittal to EPA. Following this activity we met with EPA to determine the requirements for pesticide registration of four Promac products. The FPD has askecLthat every effort be made to expedite testing. As a resultMwflaSje requested the necessary protocols which will be hand delivered to ^wt^next week at the SOT annual meeting. 2. I have been working with the^^MA-ftttbbe^ Additives Panel in developing comments onthejjj^poeed^testrule for MBT. These comments were subrnitted-~to EPAon February 28. 3. We have been notified that EPA is preparing a CHIP (Chemical Hazard Information Profile) pn^Cure-rite 18. With the assistance of the SP&C business group*T^Sa^ assembled a detailed package covering physical chemical properties, workplace and consumer exposure, environmental fate, and human and environmental effects. This is a very important project because of the attention rubber chemicals are receiving by EPA (l.e. test rules). Fortuitously, we have developed a considerable amount of data. In the futureJf,planto review information deficiencies with the product group. Hopefully if we can complete the development of a minimal database, we will be able to avoid an expensive test rule on CR-18. 4. The Estane business group is continuing to pursue potable water pipe clearances through a joint project with Shell and Insitu Form. Earlier this month we met with representatives of Shell and the N.Y. State Dept, of Health andwfevvewed the limited toxicological data on Estane polyethers with them. No estimate was given as to when we might have a response. However, Shell is taking the lead role and will keep us informed. 5. I continue to be involved^tii--ttiCT3ppion lung cancer case and am now completing m^jv+efiof the background information. My deposition and the tri4-'fsscheduled for March. 6. The New Products Group is woHpH-rgwith Velsicol in evaluating some chemicals as plant growtM'tfgulators. I have provided guidance regarding TOSCA anjPF'TF'llA test requirements. 7. ^r/^melTwi th the SP&C Group to assist them in prioritizing research to find alternatives to benzene as a solvent for Carbopol. Additional toxicity information review was requested on several solvents. BFG23145 T T006TG32 8. OSHA has begun preliminary maneuver1ng__fce'Tgulate BD. I am working with IISRP In preparing commjps-r'''We believe that the present ACGIH TLV of 10 ppm Is adequaJe-'aTfifthat OSHA does not have any scientific basis to set a standsrfcTof 1 ppm. 9. The VI Technical Committee met this montji^ai'rtr T provided an update on the baboon and rodent studies on Hl<^''fill work is proceeding satisfactorily. The medical/o*Tcolog1cal subcommittee has also been asked to review the hasfs for the EPA dioxin risk assessment; an FOI request has been ^jjblnltted to EPA. 10.3^j!&ve^repared a draft submission for compliance with the TOSCA 8d health and safety reporting rule for vinyl acetate. This draft has been submitted to the Geon Company for their review. R. K. Hinderer JP BFG23146 22919002