Document Radr7eXz3BQK3Lw2N9qLR21xE

flfcl ll. 069 INTER-OFFICE CORRESPONDENCE 1IO-TIST AUmbitt, M, OLT October 8. 1969 Files DHJ^ MLK, JP. DA. JFV, OL and CM Moniuto - Tissue Samples for Analysis in Connection with Monsanto Arodor Studies Ai Chicken Study 1- &**. The following pooled samples for each group are to be cclJoctea: 1) one pre-hatch collection, 2) one hatch collection, 3) recovery week 1. 4) recovery week 2, S) recovery week 3, 6) recovery week 4. 2. Tiisuea . Pooled samples of fat. liver, muscle and kidney from each group are to be retained at the time of the original sacrifice and at the r.- of the recovery period. An effort should be made to obtain approximately the same quantity of each tissue from each anirr.al. It is probable that Monsanto will analyze samples from only the highest no-effect lev. 1 groups. We must provide an opinion as to the identity of these groups. All other samples will be retained until the studies are complete in case there is need to do analyses on tissues from other groups. B. Reproduction Study It is desired to analyze pups from all groups at some point during the study. These pups should be sacrificed before they are old enough to begin eating the mixed diets (approximately 10 days). MLK has suggested carrying some extra Fib females for the sole purpose of collecting their pups for these analyses. 2 DEPOSITION EXHIBIT -32% to ,fT-fL 004375 STLCOPCB4030752 070 Dos Study Composite samples of liver, kidney, fst and muscle are to be col lected from dogs la each group at the time of sacrifice (40 samples). An effort should be made to obtain roughly equivalent quantities of each tissue from each animal. Male and female tissues will be pooled. In this case also, Monsanto may elect not to analyse all samplee. rtsh_3tudies Details of sampling will be settled between CM and Scott Tucker. Rat Study We are to eliminate the nine-month sampling. Male and female tissues are to be pooled. Monsanto has requested that we store the tissues and that certain samples be transmitted to them as requested. :-':psh Otis S. Fanchar 004376 STLCOPCB4030753