Document RJr7dbZp9r5GxLjpQjev0O688

% Time 1 ?, 3-935 D r . Joh n D# E l l i s 122 Sou th M ich igan Avenue Ch icago, I llin o is Dear Dr# E l l i s 1 In r e p ly t o you r l e t t e r o f Ju n e 12 t h con cer n in g a sp e o t r o gr a p h ic a n a l y si s o f a specim en o f sp in a l f l u i d , I sh ou ld Ilk to p oin t out two t h in gs# F i r s t , a sam ple of sp in a l fl u i d fo r spectrgraph ic a n a ly sis i s very lik e ly to he contami n ated w ith lead in the p rocess of c o lle c t io n , u n less a s p e c i a l l y made le a d - fr e e sp i n a l p u n ct u r e n e e d le I s u se d In w ith d r aw in g th e flu id # The huh o f th e u su a l sp in a l flu id n eed le co n t ain s sig n ific a n t amounts o f le ad and I s lik e ly to cau se m islead in g a n a ly t ic a l fin d in g s# Secon d , th e a v a i l a b l e d a t a on th e le a d con ten t o f sp in a l flu id i s r at h e r m eager w ith r e la t io n t o le a d a b so r p t io n , so t h a t a d ia g n o sis 0 th e b a si s o f su ch eviden ce i s co n sid er ab ly l e ss con clu sive th an i t would b e i f b a se d upon a n a ly se s o f b lo o d , arid more p a r t ic u la r ly , u rin e# In th e case o f b lood withdrawn fo r apectrograph ic a n a ly sis, i t I s n ecessary a lso to us a sp e c i a l n e e d le , and in t h e c a se o f an y m a t e r ia l i t is n ecessary to have a eisrefu lly prepared, ch em ically c le a n c o n t a in e r f o r th e sam ple# A n aly se s mad on m a t e r ia ls w ith out th ese p r ecau tion s ar e lik e ly to be m isle ad in g, and ar e on ly tr u stw or th y i f th e amounts o f le a d a c t u a lly foun d b y a n a ly sis ar e exceed in gly low . Th at i s to say i f th e r e su lt s ob tain ed f a l l w ith in th e normal v a lu e s, one may ign o r e t h e sig n i fic a n c e o f p o ssi b l e con t am in at ion # Thus le a d may be in some m easu re e xclu d e d b u t i t s p r esen ce can n ot be a sc e r t a in e d a c c u r a t e ly u n le ss one i s a b so lu t e ly ce r tain th at no con tam in ation h as occurred* W ithin the lim it s of th ese r e se r v at io n s we sh ou ld b e q u it e w illin g t o make a sp e c t r o gr a p h ic a n a l y sis o f a sam ple w h ich you may w ish t o sen d t o u s# Th is i s n ot a d ia g n o st ic la b o r a t o r y an d fo r t h a t r e aso n we ar e n ot in th e h ab it of ch argin g fe e s beyond th e act u al c o st of us o f c a r r y in g ou t th e a n a l y s i s , w h ich I s approxim ately 5#00 p er sam p le. Our I n t e r e st I s r a t h e r alo n g I n v e st ig a t iv e l i n e s and fo r t h a t r eason I sh ou ld be q u it e agr e e ab le to m akin g th e a n a l y si s w it h ou t c h a r ge , p r o v id in g we a r e su p p lie d w it h t h e c l i n i c a l in fo r m at io n on th e p a t ie n t # I sh ou ld h e s i t a t e t o make an I n t e r p r e t a t io n o f th e a n a l y t i c a l r e s u l t s  \\ ' %, - 11 ' . . ' . . . ' . ! ' 1 ' } V `'i'i v . v ;' !' . without having adequate information as to. the character of the lead exposure* the period of time which has elapsed since cessat ion of exposure* and the general cl i n i ca l pict u r e* . ... ;. . 'V 'v p : ; '! 'k> v k V e r y t r u l y yours* R&Ksi - ' . . ;' feerfellJ* Kehoe* M.D* ;- i; v k'" Y ; i ` ; ; . ... . '