Document RJKYo7r4enRvDvqgD3vm1k2XB

W I LLI AM J. L. M CCU LLO U G H , M. D. CL A R E N CE J. M cCU LLO U G H , M. D. JO H N W . G. H AN N ON , M. D. J. P A U L P R O U D FI T, M. D. 625-635 Wa shingt on Tr u st bu il d in g Wa sh in g t o n , Pennsyl va nia Au g u s t 8, 1941 R . A . Ke h o e , M. D. Un i v e r s i t y of Ci n c i n n a t i Ci n c i n n a t i , Oh i o De a r Do c t o r : 'j. . I hear d y our t al k i n Pi t t s b u r g h i n Ma y of t h i s y e a r on l e a d p o i s o n i n g a n d wo n d e r e d i f y o u c o u l d g i v e me s o me i n f o r ma t i o n . - I h a v e r e c e n t l y e x a mi n e d a g r o u p of me n i n t he c e r a mi c i n d u s t r y a n d f o u n d c l i n i c a l s y mp t o ms a n d s i g n s wh i c h c o u l d b e i n t e r p r e t e d as s y mp t o ms and s i g n s of l e a d p o i s o n i n g . We h a d s t u d i e s of t he u r i n e s of s e v e r a l of t he me n a n d f o u n d l e a d c o n c e n t r a t i o n v a r y i n g f r o m 0 . 2 2 5 t o 0 . 4 0 0 mi l l i g r a m per l i t er of ur i ne and ex c r et or y r at es per hour of . 0 3 7 0 t o . 025 mi l l i g r a m p e r h o u r . Th e s e me n h a v e b e e n e x p o s e d t o l e a d b o r o s i l i e a t e wh i c h we h a v e s i n c e b e e n i n f o r me d i s non- sol ubl e and non- t oxi c. As I c an f i n d n o t h i n g i n t he l i t e r a t u r e a b o u t t h i s p r o d u c t I wo n d e r e d i f y o u c o u l d i n f o r m me as t o i t ' s s o l u b i l i t y a n d t o x i c i t y a n d as t o wh e t h e r t he a b o v e c o n c e n t r a t i o n of l e a d i n t he ur i ne c oul d be t oxi c. Ve r y s i n c e r e l y , PP',G- //^Z) . J. W. G. Ha n n o n , M. D. J WG: l b a' 'Is V) `