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Proposed Agenda Page Two June 14, 1978 11:00 - 11:15 a.m. 11:15 - 11:45 a.m. 11:45 - 12:30 p.ra. 12:30 - 1:45 p.m. 2:00 - 2:30 p.m. 2:30 - 3:30 p.m. Carlo H. Tamburro, M.D. Immunological and histopathologlcal studies in chemical injury a. Antigenic markers b. Imraunocompetence c. Glycosaminoglycan studies in chemical injury and angiosarcoma d. Collagen deposition with age and malignancy H. Philip Fortwengler, M.S Research Associate Charles E. Kupchella, Ph.D. Associate Director G. Randolph Schrodt, M.D. Professor of Pathology Discussion with investigators and future research C <j ro Enrique Espinosa, M.D. Professor of Pathology Richard A. Greenberg, Ph.D. Professor of Biometry Medical Surveillance and epidemio logical studies in a chemical indus trial environment Carlo H. Tamburro, M.D. Working lunch with discussion Richard C. Feldhoff, Ph.D. Bioassay of potential carcinogens in isolated mammalian liver cells William J. Waddell, M.D. Professor of Pharmacology and Toxicology Tissue and cellular disposition of industrial chemicals Carlo H. Tamburro, M.D. et al Summary overview New future research activities Open for discussion with all the investigators VISIT OF THE MANUFACTURING CHEMISTS ASSOCIATION PROPOSED AGENDA - JUNE 14, 1978 8:30 - 9:00 a.ra 9:00 - 9:20 a.m Carlo H. Tamburro, M.D. Professor of Medicine John L, Wong, Ph.D. Professor of Chemistry 9:20 - 10:00 a.m. Uldis N. Streips, Ph.D. Assistant Professor Microbiology and Immunology Uldis N. Streips, Ph.D. 10:00 - 10:15 a.m. Joseph T. Joseph, Ph.D. Research Associate Mr. Arthur Chang Research Assistant John L. Wong, Ph.D. Carlo H. Tamburro, M.D. 10:15 - 10:45 a.m. 10:45 - 11:00 a.m Julie T. Du, Ph.D. Research Associate Richard C. Feldhoff, Ph.D. Assistant Professor of Biochemistry John L. Wong, Ph.D. Carlo H. Tamburro, M.D. Overview: Relationship between clinical research and Medical Surveillance Program Analysis and synthesis of chemicals and their use in bioassays for the identification of carcinogenic potential Discussion with investigators and future research J3 <j= cr rOo Use of biochemical enzymatic systems for the detection of vinyl chloride and other chemical toxicity in animals and man a. Biochemical studies in humans b. Animal studies Discussion with investigators and future research COFFEE BREAK