Document QwNXwXyjrQoR4RNmz6M00XNL

FILE NAME State of the Art Literature SAL DATE 1930 DOC SAL011 DOCUMENT DESCRIPTION Industry Report - Excerpts from Various Medical Journals on Pulmonary Asbestosis it; J pstyt yehogrT och ; t. : pisX ae oh ; bd aleSALA, TAS aee mas AOL woid AQT ae MoUAse y : Cait ! Vale poe A sy i tye i 2 sineens ty oo wee porwr es eo at ow erat Sy does, rathforeANTELt. =e Loiic45 wey Pate PATA,aeere & eeaAF osRIG ot ou Nn tace Bemba Lae mN . my,Sots at : | . . . [ _@ . aes t \ . , ee oe * . eee EXCERPTS EXCERPTS FROM VARIOUS MEDICAL JOURNALS ON . PULMONARY ASBESTOSIS aaet bay eae ent Cc ae MENO REPORT 122 BEL | AoE ea eaee 2 ey _ L a ae ee . ne . he March 21 1950 Market Analysis Analysis Section Sales Promotion Departaent Manville Corporation MARKET MARKET AMALYBIE AMALYBIE SECTIOM SECTIOM BALES PROMOTION PROMOTION DEPARTMENT DEPARTMENT DEPARTMENT DEPARTMENT DEPARTMENT JOHNS MANTILLE COMPOMATIC COMPOMAT COMI POMACTIC + ste FOREWORD aan ane) vo A few scattered articles have appeared in medical journals in recent years concerning occupational disease of asbestos workers noticed of late A tborough study and aiagnosis apparently disease has not yet been made as the disease has not pre- viously been generally recognized Excerpts of articles on this disease were taken from medical journale in the medical Library : eof. at Fifth Avenue and 103rd Street and are presented <n in this report r . ry 4 Macatee MARKET AMALYSIS AMALYSIS SECTION BALES PRISHUTION PRISHUTION UFPANIMENT UFPANIMENT UFPANIMENT SHOWS FLOJKATLILONFLOJKATION FLOJK FLOJKATA ION FTLOI JKAOTIN ON (- ~~ * _" EXCERPTS FROM VARIOUR MEDICALJODIJIALS JODIJIALS ASBEST ASBESO TOS1S 3 AS1 BEST3 OS13 Canadian medical Asociation Asociation Journal Feb. 1929 - Page 155 Pedley Frank G. - Pulmonary Askertorio | ae Mortality and mobility records of asbestos workers ari not available Information as to the effect of such work on the worker is extremely limited Death of an usbriston vorker which occurred in 1999 1 reported by Dr. Murray trial Diseases and the due to an occupational in England to the Deportaat of Imbsevidence suggested that the death wis discare oi study Asbestos is ergentially Cunndian asbestos asbestos is said to iron oxide a menesium silicate Tur contain about 41 zilien su 1.5 Clinleally orbentos affects two lissues First it say produce samil warty growthe in the skin the called bestos corns Secondly it may give rise to a fiimoir of the Emir somewhat similar to that produced by silien Investigation of asbestos corns indicates that they are granulontong granulontong in and have for their cure a tiny spicule of montbos fiore miture ay ^' It is believed that silic in in to the remntion of pulmonary fibrosis At present tile the occurrence of pulmonary asbestosic annot be uimprovel by since benlos it Ar is a silicate Ho amlysis has been revic of pulmoury tirauc for silica in cases of asbestosin ; It might be thought that lesion in this condition var ennen tially the same as that of ordinary siliconir if it were not for the fact that certain very chincteristic codies are report- ed unlike those seen in any other pathological picture . peter to the called curious houie Microcoole sections of bu of nobestos workers show large clongnben movies varying in length = MARKET ANALTBITIO ANALTBITIO ANALTBITIO SALFI PROMOTION UIFANIMENT UIFANIMENT SON eee ree CORONATION fi bd e _ . frforom m 10 ttoo 100 microns TThheeyy mmaannyy hive hive sim simlele clubbeal clcluubbbbeeaall uun ndd or tmsay appear as elongated dumb bell and sometimes simple coceni or streptococcal forms are seen They do not stain with ordi- nary oniline dyen brown Apparently but are tiracelvan pale yellow or yellowish they are composed of centralcentral core which is probably an ambestors spicule upon which collodial aggromles of blood proteins have been aborcofl Since the reported caseosf this diseang hove it llaarrgge el lyy a ammoonngg sppiinnnneresrs anadnd wweeaav veerrss it in in pornille pornille pornille occturngi tthhaatt thtehe miningmining and crushing of asbestos does not present a hamarn The failure to recognize the disence in Canada however in no eviomies of this for in other occupations experiene ivir chown tmt luge groups of men suffer scriour occupaltunni effects effects which go in- recognized for years _ : @eeeeoee Bulletin of Hygiene Hygiene - Junior- Dec. V. 4 12 Pap~ 078 19 ote : Abstract - Glone M. koodhonse Nood 1.A Pulmonary Asbestorin Radiographic Appearancen in kingrams of the Cheet of borkers Asbestos Tubicle 19 V. 10 85-6 12 . figures on 6 pls 12 ref The cardinal symptom of pulmonary selectoris like that of other forms of silicosis in dyspnoen whitch progresume until in the advanced stages of the disease it becomes extrein Th dyspnoca may be accompiled by cynnosie and the cumplusion of . most patients has a slightly londen hue Chest expansion may be * reduced to one inch or less Cough in -luon escorrive and ex- pectoration is moderate in mount of even nusent ~ physical signs are those of a bilateral pulmonary Fibrosis chiefly affecting the long bases Pulmonary tuberculobis may suporvene or modify the clinical picture Then Live ai 150 is well established the nosis appears to he grave veo Post mortem the diagnostic feature which server to dis- tinguish the the presence condition from other form of in the lungs of golden yellow phononoconjorie is foreign bodies wilu MARMIT A~ALTISA~ALTIS SECTION SALA POMOTION POMOTION OLCANIMENI OLCANIMENI 101145 eee TILLE LUMTUN610 LUMTUN610 segmented outline and clubbed extremitier boring boring a ruperficial resemblance to minute crustacean forms oes Fy, aeeeevave . ee D ; British Medical Journal - Sept. P. 578 23 1923 Asbestos Lust and the in Pulmonary Curious Fodies Asbestoris Found . A scientific treatment of the lysis of the found Just bodies some outstanding extracts taken I have mentioned that the greater portion of consiis of slender translucent asbestos dust of fibres In sections and extracts lung there is a recarkable paucity of there fine | The results of digestion how the fine grumlar dussptiacnudl the large black blue and brown particles emi vht vht appears to be _. pieces of quartz Relatively few fine spiales are foumait Ji curi ous bodies of all descriptions are present in enormous numbers numbers . numbers . All these fact lend un to imagine the bonies bonies central nuclei of asbestos to consist of of blood proteins plus spicules upon which collodial ug pregates pregates possibly soluble factions of and in the case of chrysotile workers an iron asbestos absorbed and talt have been moulded by currents in the bronchi and Alveoli -- --...sionalbliyotite fragments fragments into fine black if our reasoning be correct come at least of the mislpliicounleosf curious bodies should show a central core of this mineral and @eneesne Lf. MALT ORT Ets . wee, - : s a Y. Lets British Medical Journal - Sept. 28 1919 Haddow A.C. - M.D ... Clinical Aspects of Pulmonary Asbertonin Asbertonin A clinical and scientific study of specifice specifice .disease specifice of thin MARKET ANAL asbestos workers - Significant extracts taken * tee Be me Oye NSe ad rte Tote, a MAB EN mel YM ... ... ... " ... \QL 3 , 4 .: BI ce & a3 St ' a i gf o Sf ae ah as # a zs hae oe sooo. f Of these four fatal cases the average al death was 41 and the average years actually spent in the factory were under 20 all in asbestos making for most of the time The male patient had worked until two days imore dmth on a Light job but the other three had been incapacitated for an average _ two and half years 3yrs 5 mon k yra 5 nos 1 ST of 10 mos Only in one of them had tubercle builli been foun~ in the sputum o ee - %" Advanced Cases In practice these workers do not call for much attention " until they reach the stage of total incapacity Until then they are naturally more prone to chert troubles during the winter months and sometimes unfit for weeks at a tine _ -) Clinically T+ ; oS : Four women Average - 35 years of age 11 14 years spent in Inctory w 3 children apiece thil^/remall henltby ) Suffer from shortest of breath Have cough without expectoration Lenn although not losing in weight Pain is variable and occurs from time to time with localized pleurisy Hight absent 13 been no hemoptysic No tubercle bacilli have been found Heart normal - Pulse rote 90 at runt Average full range of inch in the chest upper expansion is only one thor and even leng around lower ribs . Onset of symptoms OO It is very difficult to ascertain the unte symptoms but the patients generally believe it ' years of work of onset of was after five ry ee { aN ai : . on is - eee .?, Conclusions ; - 7 The following conclusions have been established 1. That the inhalation of asbestor dust sill in the leng and run produce state of fibrosis the distribution being peripheral and basal the right base becoming more advanced and upp uppereupr per lobes tending to develop compenmitory emphysema emphysema at first the uin- | phragmatic gradually the entire pleural curfaces becoming becoming