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~ Industrial Hygiene Digest
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4U Silicosis Hazard in ft Lead and Zinc >lini in Rajasthan. Report No. 21.
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Government of India, Ministry of Labour and Employment. 78 pp. (1961).
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AVAILABLE FROM: Office ol the Chief Adviser of Factories, 2-A/3 Asaf Ali Road, New Delhi, z
India. ' PRICE: None given.
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.. This is a medical and environmental study ol the dust hazard at the Zawar lead and
zinc mine in Rajasthan, India. This mine was opened in 1942. Environmental studies included
a comparison of the weighted exposures of the different Categories of workers. Only mill work*
ers at the crushing plants were exposed to dust concentrations exceeding the threshold limits.
The silica' content of the rock averaged 22 %. The medical study was made on a sample of 17}
workers out of 606 miners and 101 workers at the concentration mill. The medical examination
included a blood examination, vital capacity'measurements, and a IS x 12 p0stenor.-ante.nor .
chest X-ray examination. The results obtained were that .52 (30. 4%) of the workers had evidence
of dust deposit in the lungs. In workers who had been employed only in the Zawar mine, the per
centage was 21.2. On the other hand, 21 (84%) of the 25 workers who had also been employed tn
other mines showed evidence of pneumoconiosis which was of a higher Category than that of the
patiente from the Zawar mine. The vital capacity measurements were not helpful. The blood
examinations revealed that 11.5% of the workers Buffered from anemia, the cause of which has
to be investigated. Recommendations :are given for improving the environmental conditions.
Medical measures recommended are examinations of new entrants, the risk of employing work ers from other mines.is noted. Periodical x-ray examination of miners and certain surface
workers is advised.
-- Cond. from Bull. Hyg.
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INDUSTRIAL MEDICAL PRACTICE
412 The Dispersal of Staphylococci in Hospital Wards. W. ,C. Noble. J. Clin. Pathol. 15.. 552-55.8 (Nov, 1962),
The air of .3 hospital wards was examined frequently for staphylococci for nearly 4
years using slit samplers. "Broadcasts'' of staphylococci into the air were observed with the
air count rising well above the mean of .0.2 staphylococcal particle per cu. ft. ,'and these broad
casts often appeared to be due to single patients. Eight of the 3,675 patients admitted to the
wards possessed an ability to disperse staphylococci into air of th wards which was markedly
greater than normal. The actual dispersal about the ward appeared to be mediated by the bed-
cloths, lor when these were disturbed, large numbers of staphylococci were disseminated into
' the air.
-- Public Health Eng, Absts.
4 I 3 Evaluation of Drugs in Industry, A Method for Comparing the Effectiveness of Drugs in the Treatment of Acute Functional Disorders. L. J. Warshaw and H. j. Bennett. Arch, Environmental Health 6 , 22 7-234 (Feb. 1963).
A method lias been elaborated fpr comparing the effectiveness of drugs tn the treat
ment of acuts functional disorders that ft particularly suitable for clinical pharmacology investi
gations conducted in the setting of the industrial medical department. Its essential features in
clude: (1.) the use of rigid arbitrary criteria for selecting suitable cases of acute functional
disorder under Investigation; (2) comparison of the drug being investigated with other more or
less effective preparations and a placebo; (3) employment of a randomized block design for as
signing suitable subjects to the different treatment groups; (4) use of the doi|ble-blind technique
to minimize observer bias; (5) observation of the number of doses and the amount of time re
quired to obtain the desired effect, the frequency of recurrences of symptoms following Initial
improvement, and the response of individual symptoms independently of the over-all response
of the patient. As a demonstration of the manner in which It may be employed, a study is des
cribed in which this method was applied to the evaluation of several drugs In the symptomatic
relief of acute gastrointestinal upset,
-- Authors' summary
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