Document QkY9EXOYqJzExb9QZ8jbNKKKk

FILE NAME Manville JMA DATE 1967 Aug 25 DOC JMA079 DOCUMENT DESCRIPTION Memo RE Asbestos and Cancer ~ j : # American American Mutual Mutual Mutual OT , 1967 fi e a ee Cu) eeeny oS prom 4 ee - ge - 49 DE ^ 49 DE @ a.) M 1 M M M M M M INFORMATION INFORI MATION NFORMATION SERVICE Cs pia diet wen enabe iM ADRS OE M M M IESE ORT 30. 67-1 IMOSTRIAL HYGIENT SERIES NO 8 American Mutual Insurance Alliance ACCIDENT & PINE PREVENTION ORPARTMENT ORPARTMENT ORPARTMENT 20 NORTH WACKER DRIVE CHICAGO ILURGIS 00000 August 25 1957 1957 AQUESTOS ARCO CANCER Aubertos has long bean recognized as a material producing a hazard to the Builth of those v^ o inbale its dust in excessive amounts over a long period of . Ortensive study of the relationship between dagres and length of expoBUFE maid the development of the lung disease zabestosis has been documented by the U. 8. Publio Health Service in the taxtile Industry 7 During the past decade more attention has been focused or the developr^m 5c^ntarof the limg and of other body areas fellowing openre to asbestos ist Besoral of these studies strongly succent the possibility that esbertos is a carcinogen a cancer producing substance 2 3 4 5 5 10 er very flu or those cancer victims have been wout of these studies are medical and exposed to asbestos alone statistical and there is no Unfortunately data respecting degree and length of exposure of those who have developed cancer ^ zualarming feature of at least two of these reports 4 10 in the suct thes parsons living in the vicinity of mines and mills processing nebestos bere developed pleural or peritoneal mesotheliorms without any occupational exposexpuosurre e . Another report 7 describes two cases of pleural mesothelioms with simitel or so esbastonis One person living in an area of mines and mills is reported to art the While several of the published studies relating asbestos to lung cubce begressive the group of studies made by Selikoff at el bave probably hat greatest impact on the general public The Buffaly of one of their cost recent studies is to be found below 5 In this study sons 2,500 autorales autorales vero revieved and azong them asbestosis was recorded to 26 cases Of these 36 four diad of pleural mesotheliom three of peritoneal mesothelioms and seven of bronchogenic carcinom an incidence of almost 54 par cent This mesothelioras contrasts with another study of 3,000 were recorded for un autopsy incidence autopsies in which of 0.07 per cent 36 Other mesothelioras studies have subex ASB ... PUGLIES704 ... ... ... Tard Fa Fa Fa Fa Fa QUQUET QUQUET COs to me Pe PUGLIES704 PUGLIES704 are br DEVELOPER DEVELOPER cen be eras BPC byt ry ; HER ARR CE Ge LM- ... ,, flaby 08976-4 08976-4 BILDE BILDE POE TE CU PMEE TEES DO EEE teces bees & * 08976-4 140 Pu ed PARTLICE ng PARTLICE ng PARTLICE ng } ti Le. oes PARTLICE ng PARTLICEng PARTLICEngPARTLICEng a j 1100-0385 * THUSTRIAL HYGIENE SERTES xo 8 eg 2 of particular revealed incidences about 0.77 per cent mesothelioms In this study there were no mesotheliomas in the absence of asbestosis Bie A second phase of the Selikoff study was concerned with the findinogf - asbestos partiales in the lungs of victims of pleural mesothelioms These partiales were found in 12 of 45 cases Asbestos is easy to find in lung : tissue and is often overlooked | The third phase of this study was an insulation workers all Of these 307 deaths four were pleural gastroicnantceerss2t 7 wiern e oathler 166 attr to oi theb r cau usestofe ded ath deaths were due to mesotheliomoavesr analysis of 307 consecutive deaths of unions in New York city and ware from breachogenic carcinos peritoneal mesotheliouns 34 vare SUMMARY - Baos n the e wd ork of the U. s Public Health Service 1 the American Conference of Industrial Hygienists has adopted a threshold linit value of five million particles per cubic foot a.p.p.c.f. 8 such produce disease whether cancer or asbestosis & threshold limit of five exposure { REFERENCES Dreesen W. C. Xt al A Study of Anbestosia 15 the Asbestos Textile ex 4 Public Health Bulletin No. 241 U. 5. Government Printing Office WashingIA D. C. 1938 8 Dall R. Nortality from Lung Cancer in Asbeston Workers Bitish Journal Bitish Bitish Bitish of Industrial Medicine 12 81-86 1955 Braun D. and Trump T. D. Epidemiological Study of lucy Chacer is Asbestos Miners AMA Archives of Environmental Health 17 634-653 gan, Nagner J. C. Blegge C. A. and Marchand P. Diffuse Pleural Moscthallons and Asbertos Exposure in North Western Cape Province Seftist Journal of Industrial Medicine 17 260-271 1960. 3 Salikoff Irving S. Churg Jacob and Hammond Cuyler E. Asbestos Exposure and Neoplas Journal of the American Medical Association 188 22-25 1964 Balikoff Irving J. Churg Jacob and Hammond Cuyler E. Relation Betwe Exposure to Asbestos and Hasothelioma New England Society of Medicine 272 11 560-555 March 18 1965 Cartior Faul Discussion of British and European Tumor Problems Archives of Industrial Bygiene and Occupational Medicine 5 262 1952 A.C.O.I.K. Threshold Limit Values for 1956 Annual Meeting A.C.S.I.E. Pittsburgh Pennsylvania May 16-17 1966 9 Quide to Diagnosis of Occupational Diseases King's Printer Castric Castric 2949 Fevhouse Mariel L. and Thompson Hilds Mesotheliom of Fleura and Perito Perito Following Exposure to Asbestos in the London Area Industrial Medicine 22 261-269 October 2955 British Jouraslg: