Document QkGy7xnyMNx63OerKGd5gvzb8

3M Katherine E . Reed, Ph .D . YN 1 E m ironmental, Health and Staff Vice President Safety Operations ~ J U~ ~ 6 6~ - 0 706 3 C/ p. 1 900 Bush -Venue . Building 4 ~_'-'E-'6 PO Box 3333 1 St_ Paul, MN 55133-3331 651 778 433 1 _ - ~$ #,~Li q Certified Mail June 29, 2006 ~"~~i~ Document Processing Cente r EPA East - Room 6428 Attn : Section 8(e) Office of Pollution Prevention and Toxics US EP A 1200 Pennsylvania Avenue NW Washington DC 20460-0001 N0c0 C131 II ~ Is~ II IeI II ~6I li~ o~!~ ~oI~~ I~nI~I 1o111 ~31i III 111~~11 111 Re : TSCA 8(e) Substantial Risk Notice : Sulfonate-based and Carboxylic-based Fluorochemicals, Docket Nos . 8EHQ-1180-374 ; 8EHQ-0381-0394 ; c =J~ 8EHQ-0598-373 - Pilot Study to Assess Serum Fluorochemical Concentratit~ in Americ an Red Cross Blood Donors, 2005 . t - ..- --~ Dear Sirs : -~ ~--t 3M is submi tt ing this notice to supplement its previous submissions on sulfonyl an d ca boxyli P based fluorochemicals . 3M has recently received the enclosed final repo rt for seru m fluorochemical concentrations in a small sample population of American Red Cross blood donors in 2005 . The purpose of this pilot study was to determine whether general population PFOS and PFOA concentrations, as measured in 2005 in a small sample of American Red Cross blood donors, may represent a decline from prior general populations measurements made in 2000 . The study found that there was an approximate 50 percent decline in serum concen trations of PFOS and PFOA consistently observed across sex and two age categories for both PFOS and PFOA . 3M does not believe that these data indicate a "substantial risk of injury to health or the environment ." Neve rt heless, 3M has decided to report these data, recognizing the ongoing work by U .S . EPA to assess fluorochemical exposure pathways and potential risks . If you have any questions, please do not hesitate to contact Dayna Blomquist at 651-736-5413 . Sincere l Ka erine E . Reed Staff Vice President Environmental, Health and Safety Operations -