Document Qk6gLnY61qoVjpko1VMBvNzkk
BFG35931
I;
* 128
Annals New York Academy of Sciences
In the (mure, periodic control examinations of oil PVC workers, especially of those engaged in VC polymerization, at short intervals employing sensitive methods should be obligatory unless it should prove feasible to eliminate com pletely any possible air contamination.
Some of the many scientific questions connected with the problem of vinyl chloride disease may not be answerable until results of further extensive animal experiments**''*'*1'"' and of prospective and retrospective large-scale studies'* as well as of continuous monitoring of working treas"'***'"*'"* are available.
References
1. Adah, Y. G., A. G. Huvos A S. I. Hajdu. 1972. Malignant vascular tumors of liver. Ann. Surg. 175: 175.
2--AmuoiiTrU-fi iistr. yiiiyrUiimiue aiumm. ciiun. Cm. 71 (mk 27)i m.
of vinyl ehloilde, Chain, Engr-94 (April tO):
___-Chew.' Cn,. VV'liuhr-,. ...
7. Anguelescu, Ft.. M. Otoiu, E. Dobrinescu, L. Haoi-Parascmiv-oossios, Gh.
Dobrinescu A V. Oania. 1969. Consideralii clinico-paiogenice asupra fenomenului Raynaud la munciiorii din industrla pollcloruril de vinil. Med. Interna , 21:473.
A 1--Aurnw, O.-Tr l9T4:'-tmhisulaliysignificant oiganie shcmicalj (Part-9). CIh.hi. Sufrt--K `ay
9. IlAAoea, E. \V. I960. Kllnische Grundlagen der sechsundvierzig meldepfiichligen Berufskrankheiten. Urban A Schwarzenberg. MQnchen, West Germany.
10. Baader. E. \V., Ed. 1961. Handbueh der gesamten Arbeitsmedlzln. Vol. 11/1:
Berufskrankheiten. Urban A Schwarzenberg. MUnchen, West Germany. It. OAdmxzAoe, M. F., S. U. Hlrtel A P. Schumacher. 1971. Hkmangloendo-
theliom (Reticulosarcoma angioplasticum) der Leber und alle Echlnokokkusinfeklion. Acta Uepato-Splcnol. lit 224.
12. Baretta, E. D., R. D. Stewart A I. E. Mutculex. 1969. Monitoring exposures
to vinyl chloride vapor; breath analysis and continuous air sampling. Am. Ind. Hyg. Assoc. J.JOtiJI.
1). Basalaev, A. V., A. N. VxztN A A. G. KodETXOV. 1972. K patogenezu Izmenenii
voznikayushtikh prl dlitcl'nom vozdeistvii vlnilkhlorida. Glgiena Truda Prof. Zabolcvaniya 16(2): 24.
14. Basu, a. K., J. Boyer, R. Biiattaciiarya, K. C. Basu Mallik A K. P. Sen Gupta.
1967. Non-cirrhotic portal Abrosis with portal hypertension: a new syndrome.
Part 1. Clinical and function studies and results of operations. Indian I. Med. Res. S5t 2)6. .
11. Basu Maluk, K. C.. X. P. Sen Gupta, A. X. Basu/S. X. Biswas, N. C. Pal A J. Uovsa. 1967. Non*clrrhotie portal Abroslt with portal hypertension: a new syndrome. Part II. Hfslopathological studies. Indian I. Med. Res. 5St 211.
-Idrllei'ic, If-rW. OuciiLea, Mi limit, Bi Kuun, Ife-Sictunam. A R. Ttwieer. 1988.
17.
- iVrti der Leuaiusiupta, P: k. fhjiallama Vet leg, 5mugni, WESt Gitfifiany. BtcKta, V. A k. BOsscttaa. 1961. Uebcr da* HKmtngloendothcliom der Leber.
Acta tlcpato-Splenol. It 256.
16. Bianciii, L. 1970. Zum Problem der LebcrAbrose. Schweiz. Med, Wochschr. lOOt
1214.
19. Bover, I. L,, ;<. P. Sen Gum, S. K. Biswas, N. C. Pal, K. C. Basu Mallik, F. L. teas -It A. X. Basu. 1967. Idiopathic portal hypertension. Comparison
v'iift.
hypertension of cirrhosis and extrahepatic portal vein obstruc-
den. A. . "mil Med. 66(1): 41.
it). bstT. '.'it.. ,i~A. Vinyl chloride and cancer. It 590.
21. BRCWi::::;;i.t,?. Sciiaffnee * H. Poffer. 1966. Fat-storing cells (lipocytes) ir. r.'jr'.jr U-t-.r. A rch. Pathol. Eli 447.
22. DhCJjj.
/; 17. Patologia da rcsinc pollviniliche. Med. Bull. 52(2): 102.
TOCKUSfcZ
Marsteller el ai: Splenomegalic Liver Disease
m
23. BttOiiL, W. 1966. Zwischcnftlle und Komplikaiionen bei der Laparoskopie und gczicllcn Leberpunktion (Ergebnis eincr Umfrage). Deut. Med. Wochschr. 9li
24. Canada, DerARTMENT of National Health and Welfare, Industrial Health Division. 1949. A guide (o the diagnosis of occupational diseases. King's
Printer. Ottawa, Ontario, Canada. 25. Carr. I., R. M. Burgison, i. F. Vitciia A I. C. Krantz. Ir. 1949. Anesthesia.
XXIV. Chemical constitution of hydrocarbons and cardiac automaticity. I.
Pharmacol. Expll. Ther. 97: 1. 26. CiiaTElain, A. & P. Motillon. 1967. Un syndrome d'acro-ostlolyse d'origine pro-
fessionelle ct de consiaiaiion nouvelle en France. I. Radiol. Electrol. Med.
Nud. 46: 277. 27. Chemical Economics Handbook. September 1973. Vinyl Chloride and Polyvinyl
Chloride Resins. Stanford Research Institute. Menlo Park, Calif. 28. Cl IEMIEWIBTSC11AFT IN ZaIILEN. VCRBANO OER ClIEMISClIEN INDUSTRIE E.V., Ed.
1972. !5lh edit. Econ-Verlag. Dilsseldorf, West Cermeny. 29. Ciienoweth, M. B. A C. L. Hake. 1962. The smaller halogenated aliphatic hy
drocarbons. Ann. Rev. Pharmacol. 2: 262. 30. Chief Insfector of Factories. 1953. Annual Report for the Year 1911. Cmd.
8772. ll.M.S.O. London, England. 31. Cook, W. A., P. M. Giever, 0. D. Dinman A H. i. Magnuson. 1971. Occupa
tional acroostcolysis. II. An industrial hygiene study. Arch. Environ. Health 22:
74. 32. CoROttR, J. M., C. Fievez, M. J. Lipivte A A. Sevrin. 1966. Acro-ostfolyse ct
llsions cutanies sssocifcs chci deux ouvriers affectft tu nettoyage d'autoclaves.
Cahiers de Mideeine du Travail (Association Profcssionnelle beige del M6de-
cins du Travail 4 janvier 1966). 33. Creecii, J. L, la. A M. N. Iounson. 1974. Angiosarcoma of liver in (he manu
facture of polyvinyl chloride. J. Occupational Med. 16: 150. 34. Caoil, M. N., L. W. Bbadv. 1. Baoosxy A L. Stanton. J965. A new agent for
splenic scanning: BMHP. Radiology 84: 492. 35. DAHLoaEM, S. 1961. Thorolrasi tumours. A review of the literature and report of
two cases. Acta Pathol. Microbiol. Scand. 53: 147.
36. Danisiievskii, S. L i N. M. Eooaov. 1961. V komofckulyarnvkh soedlnenii. Gigiens True*
37. Danzigei, H. I960. Accidental poisoning by Can. Med. Assoc. 1. 82: 828.
28. Deese, D. E. A R. E. Iovner. 1969. Vinyl a
nksikologii v khimii vysontya 5 (9): 26. on of two cases.
chronic human ex-
posure. Am. Ind. Hyg. Assoc. 1. 30: 449.
fo o --F-39.
OEAHc.emdwLtUwiiecrPW* u:.jBj.rH*a*t---W11.
W. 101
OLmauLr-ISOf k7f17Y.
40. DcvtoNEVtELiE, Da. A A. M. Flucnir. 15
des rlsines pofyvinyliques. Service Mid
ugs jiiirtlKiiiiulsr
.gique expfrimentale ires de Saint-MarccI,
Vernon, avrtl 1953. As cited InTruflerl, 41. Dimov, D. A T. Deritic. 1971. Profesii
Arhiv. Hig. Rada
Toksikol. 221 53.
42. Dinman, B. D.. W. A. Cook. W. M. Wi check. 1971. Occupational acroosleo
4agnuson A Tit. Drrniological study. Arch.
Environ. Health 22t 61.
43. Dodson. V. N.. B. D. Dinman. W. V Maonuson. 1971. Occupational aert
.. N. M. Nase A H. 1. clinical study. Arch. En-
vlron. Health 22t 83. 44. Dominingiiaus, H. 1972. KunststoBi
sortcn-Anwcndungcn. 2nd edit. VD 45. Dominihoiiau*. H. 1973. Kunmtoffe
Eigenschaften-Kunilstofl-
rf, west Germany. Oberfllchenveredeln- Urn-
fornten. 2nd edit. VDI-Verlag. DUsscldorl. *_. ' many. 46. DuaLtN, L. I. A R. 1. Vane. 1933. Occupational hazards and diagnostic signs.
47. Dublin, LI.6R. 1. Van
Occupational hazards and diagnostic signs. U. S.
Department of Labor, Division of Labor Standards. Bulletin No. 41 (revised).
U.S. ffqyctnmtnt Printing Office. Washington, D.C., f. 65. As cited in Dan-
c* CO
O\n' O
CQ
S'
i
id rH XI <u 'U Q / H H id / u 0. <u T}
24870002
64 OCCUPATION HAZARDS AND DIAGNOSTIC SIGNS
123. Turpentine
SYMPTOM, CONDITION, OB DISEASE TO LOOK FOB
Irritation of mucous membranes of eyes, nose, and upper air passages, bronchial inflammation, salivation, headache, vomiting, abdominal pain and vertigo, state of excitement resembling drunkenness, irritation of kidneys and bladder, strangury, odor of violets in urine, severe irritation of skin.
OCCUPATIONS WHICH OFFEB SUCH EXPOSUBE
Art-glass workers Cable splicers Camphor makers Oementers (rubber) Compositors Decorators (pottery) Dry cleaners Dye makers Enamelers Enamel makers Feather workers
Furniture polishers Ink (printing) makers
Insecticide makers Japan makers
Japanners
Lacquerers Lacquer makers Linoleum makers Lithographers Millinery workers
Painters
Paint makers Patent-leather makers Petroleum-refinery work
ers Pharmaceutical workers Photographic workers Polishers
Polish makers
Printers Rubber workers Sealing-wax makers Sbelluckers
Shellac makers Shoe factory operatives
Textile printers Transfer workers (pot
tery) Turpentine extractors
Varnisbers
Varnish makers Wax makers
124. Uranium
Uranium, reported to be one of the most toxic of metals. Is a source of radiant
energy. A high frequency of cancer of the lungs in Czechoslovakian miners of
uranium is beUeved to be due to the radioactivity of the ore. Very little has been published on the effects on man of exposure to uranium salts. The con ditions reported Include purpura of the legs, reduction of leukocytes, as well as diminution of red corpuscles, a reduction in urinary elimination of nitrated salts,
and an Increase in the chlorides. Experiments on animals with uranium nitrate are reported to show nephritis,
glycosuria, albuminuria, gastro-intestinal disorders, degeneration of liver, affec tions of nervous system.
OCCUPATIONS WHICH OFFEB SUCH EXPOSUBE
Dye makers Dyers
Glass mixers
I Paint makers
I Tile makers
Pharmaceutical workers Uranium miners
I Photographic workers I Uranium workers
`
125. Vanadium
SYMPTOM, CONDITION, OB DISEASE TO LOOK FOB
Anemia, cachexia, irritation of respiratory tract, dry cough resulting in hemorrhages, diarrhea or constipation, emaciation, Involvement of kidneys, hysterical manifestations, melancholia.
Alloy makers Dye makers Dyers .
Glass mixers
OCCUPATIONS WHICH OFFEB SUCH EXPOSUBE
Ink (blue) makers Mordauters Photographic workers
Sulphuric-acid workers Textile printers Vanadium-steel workers
126. Vinyl Chloride
nils compound is used in the synthesis of organic compounds, principally
resins, i 1
SYMPTOM. CONDITION, OB DISEASE TO LOOK FOB
The United States Bureau of Mines studied the acute response of guinea pigs to a single exposure to the vapors of vinyl chloride. According to this Bureau, vinyl chloride produces in these animals unsteadiness and motor
LIST OF HAZARDS, SYMPTOMS, ETC.
65
utuxiu, incomplete and Anally complete narcosis. The principal gross patho
logical findings .were congestion and edema of the lungs with hyperemia of the kidneys and liver.
This same Bureau determined that men exposed to 2.5 percent for approxi mately S minutes soon began to feel dizzy and disoriented as to space and
size of surrounding objects and complained of a burning Bensation in the soles of the feet. They immediately recovered on leaving the chamber, and
complained only of a Might headache which lasted about SO minutes.
127. Xylol. See Benzol
128. Zinc
SYMPTOM. CONDITION, OB DISEASE TO LOOK FOB
Metal-fume fever characterized by: Irritation of respiratory tract, dryness of throat, dry cough, malaise, headache, nausea, severe chills with fever, pains in limbs, shaking in limbs, sweating, leukocytosis.
Metal-fume fever may also be caused by fumes of lead, mercury, manganese, cadmium, arsenic, antimony, and many other metals. Metal-fume fever resulting from metals which may cause systemic poisoning should be regarded as a warn ing that continued exposure may have more serious effects.
OCCUPATIONS WHICH OFFEB SUCH EXPOSUBE
Blowera-out (zinc smelt ing)
Brass founders Braslers
Bronze-powder makers Bronsers
Core makers
Gulvanlzers Junk-metal refiners
Luters (zinc smelting) Metallizers
Molders (foundry) Pourers (brass foundry) Sherardlsers Welders
Zinc smelters
rf-1t m mr'->t
;?
O w-< o
.T