Document QgQ4M7kejRnmwBJogNjONwLYE

FILE NAME Manville JMA DATE 1950-1952 DOC JMA318 DOCUMENT DESCRIPTION Report - Quebec Asbestos Mining Assoc RE Dust in Asbestos Mines with Letters & Memos RECEIVED F.H.H DATE BU ; M.E.M April 27 1951 3269 - Mr. Ivan S^...bourin Aldred Building Montreal P.C. . Canada Dear Ivan Attached is a copy of the survey form which we have prepared in connection with the asbestosis and pulmonary cancer study As you know this study concerns the chest roentgenograms of cases in the files of both Doctor Cartier and Doctor Sith I have forwarded copies of this form to the earing for their comments before we process a sufficient quantity for their use If you have any sugg-- B- tions please let me know With every good with Sincerely yours AV Exc Arthur J. Torwald M.D. Director The Trudeau Foundation and The Saranac Laboratory ent 4 25821 a | we * A copy that the A copy of the letter ofof May from from Trudona report Trudona PULIONARY that the first first interin on ASBESTOSIS ANDPULIONARY CANCER sup- You portad by the Quebecreport MiningMining AssociationwasPULIONARY being sont Sup~ was being sont to If you I assume you have could assume assume copy of copies of it to Dr. this If If you - Lean got ono do you Saranac sufficient copies Copy Copy J. P, Woodard University Bellevue to Dr. Dr. Institute Institute Institute New New University 477 477 York New New York 16 New Bellevue Medical Cantar be: 4, bc M. PERSONAL ' ee IVAN IVAN SSTN MEADA'RRUGS MEADA'RRUGS NBAN 458TNTE45T8TNTET 458TNTET 458TNTET MEADA'RRUGS MONTREAL July 9th 1952 Paige Woodard Esq Executive Offices . Manville Corporation Wi 22 East 40th Street New York 16 N.Y. Dear Paige Re Saranac Asbestosis and Pulmonary Cancer First Interim Report I was away for a couple of weeks and regret much delay in forwarding you the five copies which you will find enclosed Carmen and I hope much to have the pleasure to see you and Mervyl soon at the house There are many things to talk about 10/17 encl 5 Cordial regards {i o tc . Ivan Sabourin . 6 tat PRODUCED PRODUCED fo PRODUCED - PRODUCED Murti. of Use Fell Mage is lesa clear than thie | RPT notice, it la due to the ASBESTOS FOR CANCER, of the document QA with RELATED CORRESP ag wRiSe V quality CIRCA I 5 5 Bor Cwo044 being filmed AES 2 ES ee ES SSE Or if , i A ~ . t " oe |aaaa 5 He sai os He aity HEPORT OF EXAMINATION OF ATMOSPHERIC DUST COLLECTED AT THREE ASBESTOS MINES IN THETFORD AREA October 31. 1952 Samples of atmospheric three asbestos mines in the dust vere collected at various Thetford area as follows at operations at the King mine on April 29 Bell mine on 1952 at the May 9 1952. Johnson mine on May 6 and 7 1952 and at the The sampling apparatus employed was the same Manville as that used for the dust survey at the plant of the Canadian at Asbestos Quebec on September 20 to 26 1951 and the samples Company of dust collected were subjected to studies like those made on the Manville samples 1. CONCENTRATIOCONCENNTRATION OF THE ATMOSPHERIC DUST The weight of dust shaken off each filter disk and the concentration of atmospheric dust calculated from that weight and an nasumed average sampling rate of 40 cubic feet of air per minute are shown in table 1 II SIZE DISTRIBUTION DISTRIBUTION FIBERS IN THE ATMOSPHERIC DUST he distribution of fibers longer than 5 microns as determined by suspending each sample in alcohol and examining the suspension at a magnification of 1200x is recorded in table 2 Fibers shorter than 5 particles microns were not included in the classification because fibers and of such small dimensions cannot always be differentiated from each other being NOTICE quality NOTICE filmed clear If filmed the the the due documefinltm this imagimeage - QAMA QAQAMMAA | ASBESTOS 1950 WITH MISC CANCER | RELATED RELREALATED TED RELATED Box CORRESP CORRESP CORRESP VCW04 quality quality quality less quality filmed , less Thetford Mines Quebec Asbestos Mining Assoc October 31. 1952 filmed filmed the clear | due ' due than i document document proportion an, The of fibers 20 microns or longer in size reported as a per cent of all fibers longer than 5 microns extende from a mini document this | document document mayo document mamyayoo ' of 19.5 per cent for sample J to a maximum of 43.8 per cent for sample J For the Manville samples the corresponding values were 9.5 per cent and 47.9 per cent III OF FIBERS TO PARTICLES PARTICLES THE DUST Besides making size measurements of the fibers the total number of fibers longer than 5 microns and the total number of particles in each microscopic field were counted From the data the percentage of fibers and of particles in each sample was calculated the values are listed in table 3. The percentage of fibers in the dust extended from 3.0 for sample J to 13.0 for sample J This range of values is about the sane as that reported for the N nvillesamples The number of fibers 20 microns or longer in size seemed to comprise cso - te ~ QAMAat"om = Circa ASBESTOS 1950atepniman ASBESTOS Elles En WITHWITH eh * AE MISC CANCER RELATED CANCER Box 5CORESPRPT FOR VCW044 VCW044 a somewhat greater portion of the atmospheric duct samples from the Thetford area than from the Mamville mine at Asbestos Quebec Thus the long VCW044 fibera longer than 20 microns made up more than 40 per cent of the dust VCW044 in 3 out of 29 samples from the Thetford area but in only 2 out of 28 samples from the Manville mine Also 28 out of 29 Thetford samples VCW044 VCW044 but only 23 out of 28 Kanville samples had a fiber content greater than 20 per cent Values on a per cent basle are given in table 4 is quality notice being less NOTICE Thetford Hines filmed Quebec Asbestos Nining Assoc October 31 1952 clear of it if is the the dtuoe than film ane document IV COMTENT the this image In order to obtain a single value which would indicate approximately the concentration of long fibers at the different operations the dust concentration table 1 was multiplied by the percentage of fibers longer than 20 microns table 2 and the product for each operation and each mine vas recorded table 5 An examination of suggest that a hazard from long asbestos fibers the data would be in table greatest 5 would in the Johnson mine and least in the Bell mine with the King wine and the Johns- Kanville mine occupying intermediate positions Since that rating of the four mines differs from the rating derived from clinical experience with workers exposed in those mines it is apparent that a simplified compar ison as carried out in table 5 is not justified and that a more careful and detailed study of each operation must be made The method of esti- iting total dust concentration in this study that is by weighing the dust collected on the filter paper disk and by assuming an air flow of 40 cu ft per min is only very approximate and is a possible source of error Furthermore the mumber of long fibers present in a sample bears no correlation to the weight of the sample since that weight may be influanced greatly by large particulate mineral substance other than asbestos Thus it becomes clear that air samples must be collected in a manner which will permit a total count of fibers per cubic foot of air and identification of the number of fibers below and above the mean length of ten microns That information plus the occupational history will permit correlation -QAMA -QAMA ASBESTOS . -QAMA : ASBESTOS ; WITH MISC CANCER : MISC CANCER 8ox eI. BUT FOR + ( me 9 VCW044 VCW044 1 atin! > VCW044 * VCW044 VCW04VCW044 VCW044 VCW04 Thetford Mines Quebec Asbestos Mining Assoc October 31 1952 between the concentration of long fibers the years of exposure and the occurrence of asbestosis in men who have worked in the environment of the respective samples Unfortunately the data obtained to date does not permit conclusive statements regarding the respiratory hasard attending certain jobs We are examining certain samples in an attempt to learn the relationship between the weight of sample and the total count particles vo fibers greater and less than 10 microns in length and this make possible the calculation of the mumber of particles and fibers per cubic foot of air Values derived in this way may not be entirely valid however since the volume of air sampled which can be estimated only approximately is a possible source of error It may be necessary therefore to collect samples using the electrostatic sampler technique This technique although more tedious than the filter paper method used in the previous program is a more precise one and will permit the actual count and measurement of par- ticles and fibers collected from a known volume of air If at all possible we would appreciate assistance in identifying the approximate degree of respiratory hazard attending each of the job samples Perhaps this could be accomplished in retrospect namely by spotting those which job samples which have been productive of asbestosis and those have not From previous discussions with Dr. Ken Smith and Dr. Paul Cartier it is our impression that from a chest point of view the respiratory baz- ard attending certain jobs has some referance to the following | ase a NOTICE beingquality notice less -NOT-IC-E of it if is clear --- filmed the due the - - to than film -- document the thisimageques up - ASBETOSCircaQAMA QAMA 1950WITH& Misc RELATED CANCER Box CORESP5 RPT FOR CORRESP | VCW044 VCW044 VCW044 VCW044 Thetford lines Quebec Asbestos Mining October 31 1952 ABBOC 0 - No exposure office workers etc. 2 Very slight exposure open pit . Slight exposure driller - open pit driller - underground primary crusher skipper - out side 3 - Moderate exposure floor man grader sweeper cobber 4 - Reavy exposure mill workers 5- 5- Heaviest exposure baggers The impressions however are not supported apparently by the data derived from our study of atmospheric samples collected by the filter paper method For example the bagging samples Table 1 10F 10AK 10BK from the King mine indicate a relatively low total concentration of dust per cuble foot of air and except for sample 10AK Table 2 show no relative increase in fibers longer than 20 microns which would make bagring more hazardous than other sample operations operations Attention is invited to these data with the hope that comment will be forthcoming which will allow ultimate resolution of these problems I - What operations in asbestos are attended with high total dust counts particularly operations associated also with high fiber counts - In asbentos what is the frequency suspended in the atmosphere ambient to operations in asbestos and what is the and below a mean length of 20 microns of fibers certain ratio above ATV: gn 3 What is the frequency of clinically demonstrable asbestosis correlated with 1 and 2 above 5 - qualiNtOTIyCE qfiulmaedlitNyOTICE filmed clear the due than the than document document this film image this image | - QAMA QAMA QAMA AASSBBEESSTTOOSS 1950 ASBESTOS 1950 & WITH ; CANCER Misc CANCER RELATED Misc CANCER RELATED Box CORRESP RPT CORRESP CORRESP FOR VCW044 VCW044 VCW044 VCW044 VCW044 VCW044 VCW044 Thetford Mines Quebec Asbestos Mining Association October 31 1952 Table 1 CONCENTRATION OF ATMOSPALNIC DUST AT VAJIOUS OPLIATIONS OPLIATIONS AT T^ HEEASBESTOS MINES IN TILTFORD AREA The dust samples were collected on filter pupor disks with a suction suction motor and ware forwarded to The Suranac Laboratory where the just wes suazen off and weigned and subjected to frequency studies The samples were taken in April and May 1952 Sample number Operation King mine . Weight of Volume Concentration dust sumien | of air of dust off filter zumpled grans cu ft mg per cu ft 3 K K 4 5 K K 6 7 K 3 9 K K 10 101 (K) 10B K 19 K Secondary crassing Rock storage - catwalk Rock storage tunnol Distributor - 3rd fioar Primary screening - 2nd floor Fiber screening - 3rd floor Fiberizing - jumbos Bagging - long fiber Begging snort fiber Bugging - fead to machine Graders - 3rd floor Jounson mine 1.270 0.317 4.503 11.302 4.142 3.127 10.094 0.176 0.650 1.945 1.157 2 (J) 3 J 4 J 5 J 6 J B J J 9 10 J 19 J Primary crashing Secondary cranning Rock storage - cctual Rock storag0 - tunnel Distributor - 5th floor Primary screening - 3rd floor Fiber screening = 4ta floor Fiberising - jumbos Bagging - feed to machine Graders - 5tn floor 3.065 -[ 11.095 5.500 4.438 3.626 1.035 1.387 6.896 1.204 0.890 1200 400 a0 600 600 500 400 1200 1000 600 600 1200 1200 200 600 1200 1400 1200 800 400 1200 1.1 0.3 5.6 18.8 6.9 3.9 25.2 0.1 0.7 3.2 1.9 2.6 9.3 27.5 7.4 3.0 0.7 1.2 8.6 3.0 0.7 is NOTICE quality notice being leas fl filmed clear of it fF If is the due theey to than film the this yf document Image- ~~ -QAMA ASBETOSC-IRQCAAMA 1950WITH& ; MISC RELATEDCANCER Box 5 CORESPRPT CORRESP VCW04 Thetford Mines Quebec Asbestos Mining October 31 1952 Association Table 1 Continued Sample Sumber Operation Operation Bell mine 2 B 3 B 4 B 5 B 6 B 7 B B B Primary crushing Secondary crushing Rock storage - catwalk Rock storage - tunnel Distributor Distributor - Sta floor Primary screening - 4th floor Fiber screening - 3rd floor Weight of dust stuen off filter . 3.000 1.862 2.132 0.297 0.925 1.437 0.246 Volume of air sampled Concentration Concentration | of dust 800 1400 600 1200 300 800 800 . 3.8 1.3 3.6 0.2 1.2 1.8 0.3 NquOaTlIitCNyOETICE | filmed clear if if filmed the the the than ddoocucmuenmtefniltm image image image image [ - QAMA Circa ASBESTOS QAMA | QAMA ASBESTOS 1950 ASBESTOS 1950 WITH WIWITTH H ; CANCER CANCER | MISC CANCER MISC CANCER 1 RELATED Box | CORRESP CORRESP CORRESP FOR Vso CW04 . Thetford Mines Qu^'becAsbestos Mining Association October 31 1952 Table 2 SIZE- FREQUENCY COUNTS OF FIRERS IN ATMOSPHERIC DUST COLLECTED AT THREE ASBESTOS MINES IN THETFORD ARRA The dust samples were suspended in alcohol and examined at a magnification of 1200x frecq ountsu of fe ibersn fromc Kingy mine Sumple member | 2 K 3 K Length of fiber Kieroos per cent | per cont 4 K per cent 5 8 6 K 7 K For cent | per cent | per cent 5-10 10-20 20-30 30-50 50-80 80 48.0 2804 15.7 5.9 1.9 0.0 99.9 48.6 29.7 12.6 504 2.7 0.9 99.9 39.0 22.7 16.4 12.7 5.5 3.5 99.9 46.5 27.7 10.9 8.9 4204 28.0 13.5 7.2 3704 26.2 14.9 9.3 4.0 6.3 6.5 3.0 | 3.6 [| 5.6 100.0 100.0 99.9 Semple mumber } Length of fibor microns 5-10 10-20 20-30 30-50 50-80 > 80 8 K 9 r per cent per cen 39.6 31.7 4405 31.7 13.8 13.8 6.9 5.0 6.0 2.0 fa2.3.0 100.0 200.0 10 K 101 K 10B K 19 K per cent 43.9 30.2 12.9 6.0 403 2.6 99.9 per cent | per cent | per cent 38.5 22.2 14.4 10.6 45.1 27.5 11.8 7.8 40.7 27.8 14.8 8.3 6.7 409 5.6 7,6 100.0 | 3.9 | 100.0 | 2.8 100.0 is eae beingquality notice less NOTICEweere : documentfilmed clear of it is If G2 the due theEve, to than film Ga the thisimageaww aD eed - QAMAASBESTOS e Circa Circa Circa a ee ASBESTOS 1950 WITH & ; Misc RELATEDCANCER Box CORESP5 RPT FOR CORRESP VCW044 VCW044 VCW044 VCW044 VCW044 VCW044  Also Thetford mines Quebec Asbestos Mining Association October 31 1952 Table 2 Continued of fibers from mns Sample number Length of fiber aicrons 5-10 10-20 20-30 30-50 50-80 80 Sample number Length of fiber microns an 5-10 a 10-20 20-30 30-50 50-80 80 2 B 3 B 4 B 5 B per cent 51,7 27.2 11.4 7.9 1.8 0.0 100.0 per cent | per cent | per cent 41.2 25.4 16.7 8.8 38.6 27.7 14.B 8.9 6.1 5.9 1.8 {| 4.0 100.0 99.9 39.8 30.1 13.6 8.7 4.9 2.9 100.0 6 B 7 B 8 B per cant 41.6 29.7 14.8 7.9 3.0 3.0 100.0 per cent | per cent 43.9 32.7 26.2 23.6 14.9 17.3 6.5 10.0 4.7 8.2 3.2 99.9 | 8.2 100.0 being quality HULIO filmed of IS IN the UUS LV document Lid -QAMA H2DCCirca-QAMA -QAMA 314- 1950 WITHWITH ; MISC RELATEDRLATED Box 5CORESPA VCW04 Thetford rines Quebec Asbestos Mining Association October 31 1952 Table 2 Continued Frequency counts of fibers from Johnson mine Sample mumber Length of fiber microns 5-10 10-20 20-30 30-50 50-80 > 80 2 5 3 J per cent per cent 55.8 2405 11.7 409 2.9 0.0 99.8 47.5 27.7 13.9 | 7.9 2.0 10 100.0 4 J 5 J per cent | per cent 35.3 30.4 16.7 8.8 3.9 42 100.0 36.2 25.7 16.2 10.5 6.7 sl. 100.0 6 5 per cent 33.4 22.8 18.1 12.4 7.6 57 100.0 Sample number Length of fiber microns 5-10 10-20 20.30 20.30 30-50 50-80 > 80 7 J 8 J 9 J 10 J 19 J per cent per cent 35.2 27.5 257 257 8.8 609 59 100.0 35.2 257 257 133 12.4 6.7 67 100.0 por cent Fer cent 42.1 31.4 ah 7 7.8 2.9 10 99.9 39.3 27.0 15.0 8.4 6.5 | 37 99.9 per cent 32.3 25.5 196 196 10.8 6.9 62 100.0 being being being quality filmed NOTICE filmed filmed filmed due due ddocoumcentument document film this image document image image - ; Q|AMA ASBESTOS 1950og QAMA or ASBESTOS WITH ; MISC RELATEDCANCER BoxCORESPRPT CORRESP VCW044 VCW044 VCW044 VCW044 VCW044 VCW044 . being NOTICE Thetford mines Mining Association Quebec Asbestos October 31 1952 Table 3 RATIO OF FIBERS TO PARTICLES IN ATMOSPHERIC DJST quality NOTICE filmed If filmed clear If the the than document film image document image image CONLECTED AT THREE ASBESTOS MEIES IN THETFORD AREA . l ; . suspended in alcohol seen at 1200x magrification Per cent of fibers and of parti les | ASBESTOS | QAMA Circa ASBESTOS AASSBBEESSTTOOSS Sample number 2 K 3 K I 5 I 6 X 7 X 8 K 9 K King aine Johnson nine | Bell mine Fibers | Particles Sample number | Fibers Particles Fibers m^ber Particles per cent | per cent 3.1 96.9 {1 2 J 5.5 | 9405 J 11.8 ; 3 88.2 91.5 J 1 5J 3 94.5 6 J per cent } per cent 3.0 97.0 | 32323931 | 32323931 | 95.4 90.4 32323931 32323931 87.0 92.8 per cent cent 2 B | 405 | 95.5 3 B | 6.2 4 B |} 9.0 | 93.8 | 91.0 5 B | 5.9 | 94.1 | 6 B | 5.5 9405 3 93.2 | J | 32323931 9404 B | 6.6 | 93.4 | | h 96.0 8 B 15.7 84.3 J: 3 92.1 J 32323931 3 . 5.1 o 9 J 5 32323931 95.0 | WITH WITH ; CANCER RELATED Misc CANCER CANCER Misc CANCER RELATED Box CORRESP CORRESP FOR VCW044 VCW044 VCW044 VCW044 VCW044 10 X 108 K 3 11.6 93.4 88.4 88.4 10 J _ 32323931 32323931 91.4 1 VCW044 | VCW04 108 X 5.9 94.1 _ _ ~- 19 K 7.5 92.5 19 J 11.1 88.9 Thetford Minen Quebec Asbestos Mining October 31 1952 Association Table PROPORTION OF FIHFRS LONGER THAN 20 MICROMS IN DUST ATMOSPHERIC COLLECTED AT ASBESTOS PINES IN THETFORD AREA AND AT ASBESTOS QUEBEC Proportion of long fibere longer than 20 microns in atmospheric dust samples per cent of total fiber count . per cent Per cent of included in long fibers all dust samples each category of that would be per cent of King mine Johnson mine Bell --... ---- Johne- Manville per cent | per cent | per cent | per cent 8 100 100 100 96 8 100 95 100 81 41 70 56 43 8 8 0 20 14 10 8 ") 0 0 0 being notice being quality notice quality filmed filmed the is clear due due than document ' document th^<a | document if if | QAMA CIRCA QAMA ASBESTOS WITH WITH ; CANCER RELATED Misc CANCER CANCER Box Box CORESP | CORRESP CORRESP CORRESP CORRESP | FOR = VCW044 VCW044 ' VCW044 ; VCW044 VCW044 a Table 5 Thetford mines Quebec Asbestos Mining Association October 31 1952 CONCENTRATION OF LONG FIBERS IN ATMOSPHERIC DUST ia being quality notice leas filmed clear of it is the due than to document the this .. Oo, AT ASBESTOS MINES IN THETFORD AREA AND AT ASBESTOS QUEBEC The values in this concentration table 1 table were oltained oltained by multiplying the total dust by the percentage percentage of fibers longer than 20 microns table 2 Sample number Operation N Primary crushing 3 Becondary crushing 4 Rock storage - catwalk 5 Rock storage - tunnel 6 Distributor 7 Primary screening 8 Fiber screening aga Fiberizing aga Bagging 19 Graders Concentration of fibers longer than 20 microns co per ca. ft of air King | Johnson | Bell | Manville 0.3 0.5 0.8 0.7 0.2 2.3 0.4 1.8 0.3 9.5 1.2 1.5 1.4 2.8 0.1 0.3 5.8 1.3 0.3 0.7 2.5 2.1 6.0 0.3 0.5 2.2 0.5 0.1 1 3.0 2.3 0.7 0.0 1.0 - 0.1 0.6 0.3 1 0.8 CIRCAQAMAASBESTOS QAMA ASBESTOS 1950WITH& CANCER MISC RELATEDCANCER Box 5CORESPRPT FOR VCW04 f C.MMOGE wink next convent convent - Hospital June 1950 On June 12th Dr. Cartier and I visited Dr. Lansa at his Institute of Industrial - Medicine in New York We met Dr. Helson of the Institute and Dr. William Smith of Memorial and Kettering The problem of asbestos and lung cancer was discussed and these man were asked if it would be possible to carry out some research in this field Materials to be used in any experiments would probably be 1 - Three types of pure fibres a b c Viny M or King South African Blue and Munroe These fibres should be used in two lengthsi 1 - Short 2-3 aicrons Long - 15-50 microns 11 - Atmospheric asbestos and rock dust samples taken at the breathing leval of workers in the mills i Dr. Lanza and his group will prepare a program for experimental studies 2approximate length of time it will take for the study and the cost Dr. : and I will receive copies of this proposal the Cartier On June 13th I visited Dr. Vorwald in Saranac Lake and asked him to submit a p; rogram similar to that of Dr. Lansa When these two programs are received Dr. Cartier and I will be able to make recommendations to the Q.A.M.A. Today it is impossible to say whether the research program should be carried out at Saranac or New York or the two centres in collaboration Possibly no animal ' experimenta>forpublication should be contemplated today but rather we should have a statistical survey of our men and rays as well as the general population in our two towns No one knows the cause of cancer in the lung and it is impossible to correlate absolutely the findings in animals and humans in this field For this reason it may be advisable first to study our people who live and work in the dust A further report will be made when the recommendations to the Q.A.M.A. are ready h.n Kenneth W. Smith M.D. CC K. V. Lindell A. R. Fisher GHQ Box 91 J. P. Woodard GHQ Box 91 Privileged Insurer Acest PRODUCED Confidential General Headquarters August 17 1950 S G. K. Foster - Montreal Cancer Research Please excuse the delay in commenting on was due to my inability to find a former liminary fashion the idea that was to be your letter of July letter which set up followed 28 which in pre- Attached is a copy of a letter of June 19 from Dr. K. W. Smith to C. M. Me^ awwhich I m sending to you inamuch as it appears that you did not receive a copy This was Dr. Smith's suggestion as to the setting up of the program and you will note he was to receive from Dr. Vorwald and from Dr. Lanza separate suggested programs on the basis of which may have additional information since he wrote this letter I expect to see Dr. Lansa in a day or two and will ask him what he knows about it as of this time and will pass on to you any informatIimoany We should like to be kept in touch with the developments and should hope we could have it reviewed with Dr. Langa before a program is undertaken provided that is considered the proper approach in the matter You mentioned that we are to bear a considerable portion of the expense and inasmauscDrh. Lanzias alvising with us on such problems I think it would be helpful if we could have his advice I have not discussed this with Mr. Fisher recently but I believe his viewpoint is the same as that I have expressed here ene eer A. R. Fisber Privlegd Privileged inserer Except J. P. Woodard PRODUCED FILE COPY Cancer Research WithWith my letterletter of August 17 replying to yours of July 28 I sent you a McGew Sith's mentioned that Dr. Lanse progrnaimght studies experimental program seen have Directors could for this should information least has definite oportunity further Expert Expert Expert 1. Fisher C. M. Medew Asbestos J. P. Wesdard AJL The meeting of the Q. A. M. A. is to be about September 20th I judge your suggested program can be sent in shortly from what you said here the other day JPW PRODUCED JM - 83 COPY CONFIDENTIAL C. M. McGaw Hospital August 31 1950 Pulmonary Malignancy I am enclosing copies of a letter and contract received from Dr. Lanza It will be noted that Dr. Lanza has agreed with Dr. Cartier and I that the program should consist of two parts 1 - An epidemiological or statistical study 4 2 - Animal experiments consisting of a Inhalation experiments b Implantation or injection I still believe that the statistical study can be carried out by a Canadian authority and thus be more acceptable to various groups in this Province inhalation Also I believe that the best results from ed through the Saranac Laboratory studies will be obtain- Concerning the Implantation Experiment Program proposed by Dr. Lanza I believe that their methods are sound and the results will be scientifcally interesting I would prefer to make no decision until the Saranac proposal is received The contract appears to leave little choice to the Donor if the results of the study are unfavorable to Company interests and are submitted for publication However I fail to see how they can find anything more unfavorable than that which already has been published by Merewether and Heuper 1 CC - K. V. Lindell Except JM - 83 Confidential _ | Fu September 1 1950 1/30 Industrial Hygiene Asbestos Asbestos and Lung Cancer Dr. Cartier and Dr. Smith and were later in Saranac Dr. Vorvald the matter of whether asbestos produces were hare in New York several discussing with Dr. Lansa and the proper program that would lung cancer months ago with determine Dr. Lanza was to miggest to Dr. Cartai ndeDr r. Smith what he thought would be the best approach and Dr. Vorwald was to do the same It was later to be determined what program would be undertaken Attached is my copy of the report made by Dr. Latn o tg he s two doctors After you have had a chance to review this report would you please Hu it g to Hh ugh Jackson who can in turn give it to me 001 H. M. Jackson J. P. Woodard PRODUCED JM PRODUCED